Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,629 recruiting studies in this area right now.
By phase
- Not applicable4,297
- Phase 2850
- Phase 1471
- Phase 3425
- Phase 1/Phase 2310
- Phase 4208
- Phase 2/Phase 368
Top conditions
- Lung Cancer425
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer180
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea156
- COPD143
- Breast Cancer110
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer86
- Pneumonia79
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Ovarian Cancer74
- Acute Respiratory Distress Syndrome72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)40
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California393
- Alabama174
- Arizona155
- Massachusetts128
- Florida117
- New York113
- Maryland110
- Texas90
- Pennsylvania84
- Colorado71
Recruiting studies6,629 total
- NCT07447596Recruiting
Lung health study using breathing tests and AI
This study uses a simple breathing test called oscillometry along with machine learning to better understand lung conditions like COPD, asthma, and interstitial lung disease. It may help find new ways to diagnose and track these diseases.
BarcelonaAges 18–99 - NCT05965830Recruiting
Diaphragm testing in babies using ultrasound or a breathing-recording test
This study compares two ways to measure how well a baby’s diaphragm (main breathing muscle) works in babies and children who need breathing support. It may help doctors choose the best test to guide safe breathing changes, like when to remove the breathing tube or support.
LeidenAges birth–1 year - NCT07383051Recruiting
Helping children breathe on their own after ventilator support
This trial tests whether a special type of high-flow nasal therapy can help children come off a breathing machine (ventilator) more successfully. It compares standard care with this extra support to find what works best for kids ages 2 months to 13 years.
Cairo, Cairo GovernorateAges 2 months–13 years - NCT07491497RecruitingPhase 1/Phase 2
Study of TRI-611 for ALK-positive lung cancer
This trial tests a new investigational drug called TRI-611 for people with ALK-positive non-small cell lung cancer. It is designed for people who have already tried other ALK-targeted medicines, especially lorlatinib, and whose cancer may have stopped responding to them.
San Francisco, CaliforniaAges 18 years+ - NCT06587126Recruiting
Can a Cough Monitor Work in Children?
This study tests a way to monitor coughing in children at home, including children with cystic fibrosis and healthy children. It will help researchers learn how well a cough monitor works in real life.
Aurora, ColoradoAges 1–18 - NCT06573450Recruiting
Breath test study for allergic rhinitis and asthma
This study is looking at certain substances in your breath to better understand allergic rhinitis, asthma, and the combination of both (CARAS). It could help doctors find new ways to diagnose or treat these conditions.
Henan, ZhengzhouAges 18–80 - NCT06563167Recruiting
Predicting air leaks after lung needle biopsy
This study is testing a way to predict serious air leaks (pneumothorax) after a lung needle biopsy. The goal is to find patterns that could help doctors know who might need a chest tube.
Hong KongAges 18 years+ - NCT06331364Recruiting
Treating lung infections with better antibiotic decisions in Sri Lanka
This study tests whether a new way of deciding when to use antibiotics helps patients with lower respiratory infections (like pneumonia or bronchitis) in Sri Lankan hospitals. If you were recently admitted with a new lung infection, you may be able to join.
BalapitiyaAges 14 years+ - NCT07730931Recruiting
Breathing test for lung problems after bone marrow transplant
This study tests a simple breathing test called Forced Oscillatory Technique (FOT) to detect early signs of a lung condition called bronchiolitis obliterans syndrome after a bone marrow transplant. Participating involves breathing normally into a mouthpiece during your regular lung function test.
JerusalemAges 6 months+ - NCT07729891Recruiting
Vital sign monitoring after urological surgery
This study tests a system that constantly watches your vital signs (like heart rate and blood pressure) after urological surgery, to catch problems early. It's for people who are not expected to need the Intensive Care Unit after their operation.
Parma, ParmaAges 18 years+ - NCT06556433Recruiting
Smoking Cessation Trial with Family Support and Financial Incentives
This study tests whether offering financial rewards to both you and a family member can help you quit smoking. You will be asked to quit smoking, and both you and your nominated family member can earn payments for meeting certain milestones.
Anchorage, AlaskaAges 18 years+ - NCT06546943Recruiting
Glucose monitoring in youth with cystic fibrosis
This study uses a continuous glucose monitor (a small sensor on the arm) to track blood sugar levels in young people with cystic fibrosis during a lung infection flare-up (called a pulmonary exacerbation). It aims to see if glucose changes can help guide treatment.
Aurora, ColoradoAges 6–25 - NCT06575530RecruitingPhase 4
Remimazolam for sedation after non-cardiac surgery
This trial tests a sedative called remimazolam besylate in patients who need a breathing tube and light sedation after non-cardiac surgery. The goal is to see if it works well and is safe.
Beijing, Beijing MunicipalityAges 18–64 - NCT06990711RecruitingPhase 1
Siltuximab for antibody-mediated rejection after lung transplant
This trial tests a drug called siltuximab to see if it can help treat a type of lung rejection called antibody-mediated rejection (AMR) in people who have had a lung transplant. You may be eligible if you are currently hospitalized for AMR and are already planning to receive standard treatments.
St Louis, MissouriAges 18 years+ - NCT06545851Recruiting
Automatic oxygen system for exercise with low oxygen
This trial tests an automatic oxygen system that adjusts how much oxygen you get during exercise, so you can breathe easier and exercise more safely. It may help if you have a chronic lung disease and low oxygen levels during activity.
Schönau am Königssee, BavariaAges 18–80 - NCT05991193Recruiting
Study for lung cancer with brain spread and EGFR mutation
This trial tests a treatment for people with advanced non-small cell lung cancer that has spread to the brain or spine. It is for those whose cancer has a specific EGFR mutation (19Del or L858R) and who have not yet received treatment for their advanced cancer.
Changsha, HunanAges 18 years+ - NCT06537531Recruiting
Video study of breathing tube placement in Spain
This trial records videos of the breathing tube placement process during planned surgeries at hospitals in Spain and Portugal. The goal is to study different techniques and improve safety.
Madrid, MadridAges 18–90 - NCT06535074Recruiting
Monitoring lung function in preterm babies with low oxygen
This study looks at how well a non-invasive device can monitor lung function in preterm babies who have frequent drops in their oxygen levels (hypoxemia). The goal is to help doctors better track and care for these babies.
New Brunswick, New JerseyAges Any age - NCT06532591RecruitingPhase 2
Cadonilimab plus chemo before and after lung cancer surgery
This trial tests a new immunotherapy drug (cadonilimab) combined with standard chemotherapy, given before and after surgery for lung cancer that has very low PD-L1. The goal is to see if this combination helps shrink the tumor and prevents it from coming back.
Chengdu, SichuanAges 18–70 - NCT06528743Recruiting
Testing primer shot radiotherapy for lung cancer
This study is testing a new way of giving a very short, high-dose radiation treatment (called 'primer shot' radiotherapy) for people with non-small cell lung cancer. The goal is to see if it’s safe and practical for shrinking the main lung tumor and relieving symptoms.
AmsterdamAges 18 years+ - NCT06525857Recruiting
Observing body changes in long-term oxygen therapy
This study will observe how patients with chronic lung diseases change when they start long-term oxygen therapy at home. It aims to understand how the body adapts to oxygen treatment over time.
BernAges 18 years+ - NCT06520605Recruiting
CMV reactivation in ICU patients on ventilators for a week or more
This study looks at whether a common virus called cytomegalovirus (CMV) becomes active again in ICU patients who need a breathing machine for a week or more. It may help doctors understand who is at risk and how to better care for them.
Lucknow, Uttar PradeshAges 18–80 - NCT07102043Enrolling by invitation
Glucose study in cystic fibrosis related diabetes
This study looks at how the body handles sugar in people with cystic fibrosis related diabetes. Researchers want to learn more about glucose metabolism to improve care for people with CFRD.
Birmingham, AlabamaAges 21–75 - NCT06516198Recruiting
Ear acupressure before lung surgery
This study tests whether ear acupressure can help people get stronger before major lung surgery. You'll wear small seeds on your ears and do exercise prehabilitation.
Chicago, IllinoisAges 50 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,629 recruiting pulmonology studies from the U.S. registry right now, out of 10,546 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.