Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,347 recruiting studies in this area right now.
By phase
- Not applicable4,045
- Phase 2834
- Phase 1458
- Phase 3422
- Phase 1/Phase 2311
- Phase 4213
- Phase 2/Phase 364
Top conditions
- Lung Cancer415
- Asthma193
- Non-Small Cell Lung Cancer182
- Non Small Cell Lung Cancer178
- Non-small Cell Lung Cancer157
- Obstructive Sleep Apnea142
- COPD133
- Breast Cancer111
- Pulmonary Hypertension104
- COVID-1988
- Colorectal Cancer88
- NSCLC87
- Chronic Obstructive Pulmonary Disease85
- Chronic Obstructive Pulmonary Disease (COPD)78
- Cystic Fibrosis77
- Interstitial Lung Disease75
- Ovarian Cancer71
- Pneumonia69
Leading sponsors
- Assistance Publique - Hôpitaux de Paris73
- AstraZeneca65
- Mayo Clinic52
- M.D. Anderson Cancer Center45
- National Cancer Institute (NCI)42
- VA Office of Research and Development40
- Shanghai Chest Hospital35
- Memorial Sloan Kettering Cancer Center33
- University Health Network, Toronto33
- GlaxoSmithKline30
Where studies are running
- California383
- Alabama175
- Arizona154
- Florida121
- Massachusetts120
- Maryland114
- New York111
- Texas87
- Pennsylvania81
- Illinois73
Recruiting studies6,347 total
- NCT07555483RecruitingPhase 3
Weekly injection vs IV infusion for alpha-1 antitrypsin deficiency
This trial tests whether a new weekly injection form of alpha-1 antitrypsin replacement therapy (a protein your body lacks) works as well as the standard IV infusion you may currently receive. The goal is to offer a more convenient treatment option for people with alpha-1 antitrypsin deficiency (a genetic lung condition).
Birmingham, AlabamaAges 18–80 - NCT07559019RecruitingPhase 1
Safety study of BI115 for advanced small cell lung cancer
This early-stage trial tests a new immunotherapy drug called BI115 in people with advanced small cell lung cancer (a fast-growing type of lung cancer). The study will check if the drug is safe and whether it helps slow or shrink the cancer.
Chongqing, Chongqing MunicipalityAges 18–75 - NCT06598930Recruiting
Nurse-led follow-up after mild lung blood clot
This study compares two ways of following up after a non-severe pulmonary embolism: standard medical care alone versus intensive monitoring that includes an advanced practice nurse. The goal is to see if the nurse-led follow-up improves your recovery and quality of life.
DijonAges 18 years+ - NCT06739928RecruitingPhase 2
Irinotecan liposome with immunotherapy for extensive-stage small cell lung cancer
This trial tests a combination of irinotecan liposome (a chemotherapy) or etoposide with adebrelimab (an immunotherapy) and carboplatin for people with extensive-stage small cell lung cancer who haven't had prior treatment. It aims to see if these combinations are safe and effective.
Guangzhou, GuangzhouAges 18–70 - NCT06281678RecruitingPhase 2
Study of IBI363 for advanced solid tumors
This trial tests a new drug called IBI363 for people with advanced solid tumors. It aims to see if the drug is safe and effective. You may be able to join if you are generally well and have not had other cancer treatments recently.
San Francisco, CaliforniaAges 18 years+ - NCT06699433Recruiting
AI virtual pediatric patient training for primary care doctors
This trial uses artificial intelligence to create virtual standardized pediatric patients. It helps train doctors who work in primary care settings, like community health centers and clinics.
Guiyang, GuizhouAges Any age - NCT06732674Recruiting
Home-based care for lung disease in rheumatic conditions
This trial tests whether people with lung disease caused by a rheumatic condition can safely manage their care at home using a smartphone or tablet. It aims to see if home monitoring is as effective as in-person visits for keeping your lungs healthy.
OsloAges 18 years+ - NCT06742021Recruiting
MRI test to predict immune therapy response in lung cancer
This trial uses a special MRI technique (4D FreeBreathing) to see if it can predict how well immune therapy or targeted therapy works for your lung cancer. It may help doctors choose the best treatment for you more quickly.
Kunming, YunnanAges 18–75 - NCT04654650Recruiting
Study of adults with pulmonary hypertension for long-term data
This study follows adults with pulmonary hypertension over the long term and collects information (and possibly samples) to better understand how the condition changes over time. It may help researchers learn what factors affect outcomes, which can improve care in the future.
Hamburg, Free and Hanseatic City of HamburgAges 18 years+ - NCT07550218Recruiting
Surfactant Delivery Methods for Premature Babies with Breathing Problems
This study looks at different ways doctors give a life-saving medication called surfactant to premature babies who are struggling to breathe. Researchers want to understand which delivery methods work best and help improve care.
GothenburgAges Any age - NCT07546981RecruitingPhase 3
New Asthma Inhaler for People on Standard Therapy
This study tests a new three-part asthma inhaler (CHF 5993) in people whose asthma isn't well-controlled even though they're already using two standard asthma medicines together. The goal is to see if adding this new medicine helps control asthma better.
Beijing, Chaoyang DistrictAges 18–75 - NCT07545564Enrolling by invitationPhase 4
Immune Response Study of Nasal Flu Vaccine in Children
This study measures how your child's body builds immunity after receiving a nasal spray flu vaccine. Researchers will collect samples to understand how the vaccine triggers the immune system to protect against influenza.
Hohhot, Inner MongoliaAges 3–17 - NCT06074614Recruiting
Breathing and brain control in Parkinson's disease
This study looks at how the brain controls breathing in people with Parkinson's disease compared to healthy volunteers. It may help us understand breathing problems that can occur in Parkinson's.
Nijmegen, GelderlandAges 18 years+ - NCT06532591RecruitingPhase 2
Cadonilimab plus chemo before and after lung cancer surgery
This trial tests a new immunotherapy drug (cadonilimab) combined with standard chemotherapy, given before and after surgery for lung cancer that has very low PD-L1. The goal is to see if this combination helps shrink the tumor and prevents it from coming back.
Chengdu, SichuanAges 18–70 - NCT07551258Recruiting
Immune System Changes and Lung Infection in Critically Ill Older Adults
This study looks at how the immune system changes in older patients on breathing machines in the ICU, and whether these changes affect the risk of developing pneumonia. Understanding this may help doctors better protect critically ill patients from infection.
L'Hospitalet de Llobregat, BarcelonaAges 18 years+ - NCT07545304Recruiting
Testing MRI scans to help diagnose childhood lung disease
This study tests whether MRI (a safe imaging scan) can help doctors diagnose a specific type of lung disease in children. Your child would have an MRI scan to see if it gives doctors useful information before they do a procedure called a bronchoscopy.
SheffieldAges 5–17 - NCT07543601Recruiting
Better COPD care for people evaluated for lung cancer
This trial tests whether people being checked for possible lung cancer can also get improved care for a breathing condition called COPD (chronic obstructive pulmonary disease). It focuses on patients whose lung function tests show airflow problems.
VejleAges 18 years+ - NCT07543588Recruiting
Physiotherapy assessment for unexplained breathing problems
This study evaluates how physiotherapy can help adults with unexplained breathlessness or breathing pattern problems. Breathing pattern disorder happens when your breathing becomes inefficient or irregular without an obvious lung or heart disease—and physio may help retrain how you breathe.
London, LondonAges 18 years+ - NCT07548060RecruitingPhase 2
New drug combination for advanced lung cancer after prior treatments
This trial tests two newer drugs (sacituzumab tirumotecan and furmonertinib) together for patients with advanced non-squamous lung cancer whose tumors have specific genetic mutations and have stopped responding to earlier EGFR-targeted drugs and chemotherapy. The goal is to find out if this combination can help patients whose cancer has progressed.
Tianjin, Tianjin MunicipalityAges 18–75 - NCT07545499Recruiting
Daily rhythms and physical recovery after COVID-19
This study looks at how your body's natural daily rhythms (sleep-wake cycles, energy patterns) affect physical function and daily activities in people recovering from long COVID. Understanding these patterns may help develop better recovery strategies.
Ankara, AltindağAges 18–65 - NCT07550738Recruiting
Breathing machine settings during laparoscopic cancer surgery
This study compares two different ways of controlling breathing machines during laparoscopic (minimally invasive) abdominal cancer surgery. Researchers want to see which method keeps your heart and blood flow stable and protects your lungs during surgery.
AsyutAges 20–80 - NCT07543939Recruiting
Breathing measurements during minimally invasive abdominal surgery
This study measures how your lungs respond to a specific breathing machine setting during planned abdominal surgery. Understanding these measurements may help doctors use ventilation (breathing assistance) more safely during surgery.
RiyadhAges 18–65 - NCT07545954RecruitingPhase 1
DSP-0390 plus Atezolizumab for Small Cell Lung Cancer
This trial tests a new drug called DSP-0390 combined with atezolizumab (an immunotherapy) in patients with small cell lung cancer who have already completed initial chemotherapy treatment. The goal is to see if this combination can help prevent the cancer from coming back or growing.
St Louis, MissouriAges 18 years+ - NCT07549555Recruiting
Chest Wall Vibration After Lung Surgery to Help Breathing
This trial tests whether gentle vibrations applied to your chest wall after lung surgery can help you breathe better and reduce how long you need a chest tube (a tube that drains fluid from around your lungs). The study includes patients recovering in the hospital after thoracic surgery.
IstanbulAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,347 recruiting pulmonology studies from the U.S. registry right now, out of 9,965 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.