Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,629 recruiting studies in this area right now.
By phase
- Not applicable4,297
- Phase 2850
- Phase 1471
- Phase 3425
- Phase 1/Phase 2310
- Phase 4208
- Phase 2/Phase 368
Top conditions
- Lung Cancer425
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer180
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea156
- COPD143
- Breast Cancer110
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer86
- Pneumonia79
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Ovarian Cancer74
- Acute Respiratory Distress Syndrome72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)40
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California393
- Alabama174
- Arizona155
- Massachusetts128
- Florida117
- New York113
- Maryland110
- Texas90
- Pennsylvania84
- Colorado71
Recruiting studies6,629 total
- NCT06499480Recruiting
Italian registry of allergy shots and drops
This trial collects information from people of all ages who have allergic rhinitis, conjunctivitis, or asthma and are prescribed allergy immunotherapy (shots or drops). The goal is to understand how these treatments work in real life.
Rozzano, MilanoAges 1 year+ - NCT06107907Recruiting
Oxygen flow and pressure in heart failure patients
This study tests a new way to measure pressure in your lungs while you receive high-flow oxygen therapy. It may help doctors better understand how to use this treatment in people with heart failure who need extra breathing support.
TaipeiAges 18 years+ - NCT02282969Recruiting
Testing a lung cancer screening decision helper for eligible adults
This study tests a patient “decision aid” to help people decide about lung cancer screening. It may help you understand risks and benefits and feel more confident about next steps.
Galveston, TexasAges 55–80 - NCT07301151Recruiting
Quit smoking study for Black adults in Minnesota
This study tests a smartphone app to help Black adults in Minnesota who smoke quit smoking. You'll use the app to track your progress and get reminders.
Minneapolis, MinnesotaAges 21 years+ - NCT05536505RecruitingPhase 2
After-surgery targeted pill to prevent relapse in EGFR lung cancer
This Phase 2 trial studies whether an EGFR-targeted pill, given after surgery, can reduce the chance of lung cancer coming back. It specifically looks at people whose tumors have certain EGFR changes and where “minimal residual disease” (tiny leftover cancer) is being used to guide treatment.
BeijingAges 18–80 - NCT06479421Recruiting
AI study to personalize care for sudden breathing failure
This study is developing an artificial intelligence (AI) tool to help doctors choose the best treatment for people with sudden breathing failure. It compares patients who need breathing support to those who do not, to find patterns that improve care.
Seoul, GangnamAges 18 years+ - NCT07728279Enrolling by invitation
Breathing muscle training and brain health in older adults
This study tests whether a special breathing muscle exercise program can improve thinking and memory in adults aged 60 and older. If you are generally healthy and can walk and communicate on your own, you may be able to join.
Istanbul, IstanbulAges 60 years+ - NCT06467318RecruitingPhase 1/Phase 2
Do painkillers affect lung sealing surgery?
This trial is testing whether common painkillers (NSAIDs like ibuprofen) affect how well a surgery to seal a collapsed lung works. If you have a collapsed lung and are planning surgery to fix it, this study may help find the best way to manage your pain afterward.
CairoAges Any age - NCT06464224Recruiting
Breathing effort patterns in patients coming off the ventilator
This study observes how your breathing effort changes as doctors try to remove you from the breathing machine (ventilator). It helps understand why some patients have trouble breathing on their own after being on the ventilator.
Rio de JaneiroAges 18 years+ - NCT06453421Recruiting
Breathing and exercise rehab for long-term breathing machine patients
This study tests a special breathing and exercise program for people who have been on a breathing machine for a long time through a tracheostomy. The program is designed to help them get stronger and breathe better.
FlorenceAges 18 years+ - NCT06424314Recruiting
Trial on why some patients fail to come off a ventilator
This trial is studying why some people have trouble coming off a breathing machine (ventilator). It's for patients who've been on a ventilator for at least 2 days and don't have certain other conditions.
Guangzhou, GuangdongAges 18 years+ - NCT06043973RecruitingPhase 3
Almonertinib plus anlotinib for first-line advanced lung cancer
This trial tests a combination of two targeted drugs (almonertinib and anlotinib) as first treatment for advanced non-small cell lung cancer that has specific gene changes (EGFR and TP53 mutations). The goal is to see if the pair works better than standard care.
Jinan, ShandongAges 18–75 - NCT06548802RecruitingPhase 1/Phase 2
Baricitinib for lung injury after brain bleed
This trial tests a pill called baricitinib to see if it helps people recover from lung injury after a brain bleed. It is for patients who need a breathing machine due to ARDS that started within a week of the bleed.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT06412081Recruiting
Lung ultrasound to guide physical therapy for breathing problems
This study tests whether using lung ultrasound can help guide physical therapy for hospitalized patients with new breathing problems. It aims to make therapy safer and more effective by seeing how the lungs look in real time.
Brussels, Brussels CapitalAges 18 years+ - NCT07052669RecruitingPhase 3
Shorter Chemo-Radiation Plus Immunotherapy for Stage III Lung Cancer
This trial tests a new schedule of chemo-radiation (fewer, stronger sessions) followed by an immunotherapy drug called tislelizumab. The goal is to see if this approach works better than the standard longer schedule for people with stage III lung cancer that can't be surgically removed.
Chongqing, Chongqing MunicipalityAges 18–75 - NCT07467265Recruiting
Testing a breathing test to safely remove ventilators
This study is testing a simple way to measure how well you breathe on your own when coming off a ventilator in the ICU. It helps doctors decide the best time to safely remove the breathing tube.
Cairo, AbbasiaAges 22 years+ - NCT06396767Recruiting
Breathing test before heart surgery to predict lung problems
This study uses a simple breathing test before scheduled heart surgery to see if it can help predict breathing or lung complications after the operation. The results may help doctors identify patients who need extra support during recovery.
London, OntarioAges 19–99 - NCT07676435RecruitingPhase 2
Fisetin trial for healthy lung aging
This study tests whether a natural supplement called fisetin can help slow lung decline in older adults who are either lifelong nonsmokers or long-term smokers. You would take fisetin or a placebo for a period and be monitored regularly.
Los Angeles, CaliforniaAges 60 years+ - NCT05906082Recruiting
Vape-free texting program for young adults in rural North Dakota
This pilot study tests whether vape-free coaching by text message can help people quit e-cigarettes. You may be eligible if you are a young adult who vapes daily and plans to quit within a month.
Milwaukee, WisconsinAges 18–24 - NCT06367218Recruiting
Opioid-free anesthesia with spontaneous breathing for VATS lung nodule surgery
This trial tests a way to do VATS lung nodule surgery without using strong painkillers (opioids) and while you keep breathing on your own. It may help you recover faster with fewer side effects.
Wuhan, HubeiAges 18–70 - NCT06361589Recruiting
Lorlatinib for advanced ALK-positive lung cancer
This study is testing a targeted therapy called lorlatinib in people with advanced ALK-positive lung cancer. It aims to see how well this oral medication works in a real-world setting.
Chengdu, SichuanAges 18 years+ - NCT07219290Enrolling by invitation
Lung function study based on birth order in the litter
This study looks at how your lung function might be related to your position in your mother's litter. It may help us understand more about breathing health.
Fresno, CaliforniaAges 18–65 - NCT06334562Recruiting
Study of domestic sugammadex for reversing muscle relaxants after lung surgery
This study tests a domestic version of sugammadex sodium (a drug that reverses muscle relaxants) after lung surgery. It aims to see how well it works to help you wake up and recover from anesthesia.
Yiwu, ZhejiangAges 19–75 - NCT06319274RecruitingPhase 2
Prostacyclin for lung infection patients on a ventilator
This study tests a medicine called prostacyclin (given through a vein) to see if it helps people on a breathing machine with a lung infection. The goal is to reduce inflammation and improve recovery.
CopenhagenAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,629 recruiting pulmonology studies from the U.S. registry right now, out of 10,546 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.