Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,347 recruiting studies in this area right now.
By phase
- Not applicable4,045
- Phase 2834
- Phase 1458
- Phase 3422
- Phase 1/Phase 2311
- Phase 4213
- Phase 2/Phase 364
Top conditions
- Lung Cancer415
- Asthma193
- Non-Small Cell Lung Cancer182
- Non Small Cell Lung Cancer178
- Non-small Cell Lung Cancer157
- Obstructive Sleep Apnea142
- COPD133
- Breast Cancer111
- Pulmonary Hypertension104
- COVID-1988
- Colorectal Cancer88
- NSCLC87
- Chronic Obstructive Pulmonary Disease85
- Chronic Obstructive Pulmonary Disease (COPD)78
- Cystic Fibrosis77
- Interstitial Lung Disease75
- Ovarian Cancer71
- Pneumonia69
Leading sponsors
- Assistance Publique - Hôpitaux de Paris73
- AstraZeneca65
- Mayo Clinic52
- M.D. Anderson Cancer Center45
- National Cancer Institute (NCI)42
- VA Office of Research and Development40
- Shanghai Chest Hospital35
- Memorial Sloan Kettering Cancer Center33
- University Health Network, Toronto33
- GlaxoSmithKline30
Where studies are running
- California383
- Alabama175
- Arizona154
- Florida121
- Massachusetts120
- Maryland114
- New York111
- Texas87
- Pennsylvania81
- Illinois73
Recruiting studies6,347 total
- NCT07545954RecruitingPhase 1
DSP-0390 plus Atezolizumab for Small Cell Lung Cancer
This trial tests a new drug called DSP-0390 combined with atezolizumab (an immunotherapy) in patients with small cell lung cancer who have already completed initial chemotherapy treatment. The goal is to see if this combination can help prevent the cancer from coming back or growing.
St Louis, MissouriAges 18 years+ - NCT05233605Recruiting
Study sedative effects on ongoing brain inflammation after severe COVID
This study looks at whether a specific ICU sedative (dexmedetomidine) affects long-term inflammation in the brain after severe COVID with ARDS and deep sedation. It uses PET and MRI scans and special tracers to understand persistent inflammation and why it may last.
ParisAges 18–74 - NCT06156943Recruiting
Fluid monitoring during lung surgery for high-risk patients
This study tests a new way to monitor your body's fluid levels during lung surgery, especially for patients who are at higher risk for complications. The goal is to improve recovery and reduce problems after surgery.
BronAges 18–80 - NCT06020716RecruitingPhase 4
Antibiotics for chronic wet cough in toddlers
This study tests whether the antibiotic Augmentin helps children aged 9 months to 3 years with long-lasting wet cough (more than 4 weeks). It aims to find better ways to treat and understand this common problem in toddlers.
ÅlesundAges 9 months–3 years - NCT06254313Recruiting
Studying neutrophils in flu-related lung injury
This trial looks at how a type of white blood cell affects lung inflammation in people with severe influenza. It may help researchers find better treatments for respiratory failure caused by the flu or other infections.
BordeauxAges 18 years+ - NCT07536308RecruitingPhase 1
Nasal COVID-19 booster vaccine safety trial
This trial tests a new nasal spray COVID-19 booster vaccine. It aims to see if the vaccine is safe and produces a strong immune response when given through the nose and inhaled, in people who have already been vaccinated.
Decatur, GeorgiaAges 18–64 - NCT06454838Recruiting
Exercise and blood vessel health in children with pulmonary hypertension
This study looks at how exercise affects the lungs, blood vessels, and oxygen use in children with pulmonary arterial hypertension (high blood pressure in the lungs). It compares them to healthy children to understand how the condition impacts the body.
Ankara, ÇankayaAges 6–18 - NCT07540988RecruitingPhase 3
Testing Nerandomilast for Scarring Lung Disease
This study tests whether a new drug called nerandomilast can slow down scarring in the lungs for people with certain types of fibrosing interstitial lung disease (a condition where lung tissue becomes thick and scarred). You may qualify if you have lung scarring that is getting worse and haven't tried this or similar drugs before.
Birmingham, AlabamaAges 18 years+ - NCT07541170RecruitingPhase 3
Testing divarasib after lung cancer surgery and chemotherapy
This study tests whether a drug called divarasib can help prevent lung cancer from coming back after surgery and initial treatment. You would only qualify if your cancer has a specific genetic mutation (KRAS G12C) and you've already had surgery and chemotherapy with immunotherapy.
Clovis, CaliforniaAges 18 years+ - NCT07540572RecruitingPhase 1
Testing IDE574 safety and effectiveness in advanced solid tumors
This early-stage trial tests a new drug called IDE574 to see if it is safe and effective in treating advanced cancers that have spread or stopped responding to standard treatments. The trial focuses mainly on hormone-receptor positive breast cancer, but also includes lung, prostate, and colorectal cancers.
Plantation, FloridaAges 18–99 - NCT07538804RecruitingPhase 1/Phase 2
Testing ANS02 for EGFR-Mutated Lung Cancer
This trial tests a new drug called ANS02 in people with non-small cell lung cancer (a common type of lung cancer) that has a specific genetic change called an EGFR mutation. The drug is designed to target and slow cancer growth in people with this mutation.
Fairfax, VirginiaAges 18 years+ - NCT07542210Recruiting
Understanding Why Patients Stop or Continue Lung Cancer Treatment
This research study asks lung cancer patients and their doctors about their experiences taking osimertinib (a targeted cancer medication) after surgery. Researchers want to understand what helps patients stay on this treatment and what makes it hard to continue, so they can better support patients in the future.
BeijingAges 18 years+ - NCT06693362RecruitingPhase 1
Stem cell therapy for severe viral pneumonia
This trial tests whether injecting stem cells from the womb's blood supply can help treat severe viral pneumonia. It aims to improve recovery for people who are very sick and need hospital care.
Shanghai, Shanghai MunicipalityAges 18–85 - NCT07537517Recruiting
Understanding heart failure and blood vessel pressure changes
This research study examines how certain biological pathways work in patients with heart failure who need heart catheterization (a procedure to measure heart pressures). By understanding these pathways, researchers hope to develop better treatments for pulmonary hypertension, a condition where blood pressure in the lungs becomes dangerously high.
Madrid, MadridAges 18 years+ - NCT07536477Recruiting
High-flow oxygen versus standard oxygen for altitude lung swelling
This trial tests whether high-flow oxygen (delivered through a special nasal tube) works better than standard oxygen therapy for a condition called high-altitude pulmonary edema (HAPE)—fluid buildup in the lungs caused by rapid ascent to high altitude. The study aims to see which approach helps patients breathe better and recover faster.
Xigazê, TibetAges 18 years+ - NCT07541638Recruiting
Early Lung Fibrosis Detection in Rheumatic Diseases
This study helps doctors identify early signs of lung scarring (fibrosis) in patients with autoimmune diseases like scleroderma, rheumatoid arthritis, and Sjögren's syndrome. By catching this early, researchers hope to better understand and treat these complications.
RomaAges 18–75 - NCT07542301Recruiting
Breathing Patterns in Premature Babies During Extubation
This study watches how premature babies breathe before and after removal of their breathing tube. By measuring breathing patterns, doctors hope to better understand when babies are ready to breathe on their own and improve outcomes.
Newark, DelawareAges birth–6 months - NCT07535463RecruitingPhase 1/Phase 2
Ivonescimab, chemotherapy, and radiation for lung cancer with brain tumors
This study tests a combination of a new immunotherapy drug (ivonescimab), standard chemotherapy, and focused radiation (stereotactic radiosurgery) for non-small cell lung cancer that has spread to the brain. The goal is to see if this combination can shrink tumors in both the lungs and brain.
Basking Ridge, New JerseyAges 18 years+ - NCT07536984Enrolling by invitation
Personalized Oxygen Levels for Breathing Machine Patients
This study tests whether adjusting oxygen levels on a breathing machine (ventilator) to match each patient's individual needs improves outcomes. Doctors will carefully monitor your oxygen levels and see how different targets affect your recovery.
Nashville, TennesseeAges 18 years+ - NCT07542366Recruiting
Testing a new lung imaging method in ICU patients
This study tests whether a special imaging technique called EIT (electrical impedance tomography) combined with a safe contrast injection can measure blood flow in the lungs of patients on breathing machines. If it works, it could help doctors better manage critically ill patients.
Wuhu, AnhuiAges 18 years+ - NCT07536256Recruiting
Youth Resilience Through Native Hawaiian Culture in Wai'anae
This program connects young people in the Wai'anae community with culturally rooted activities and support to build resilience and improve physical and mental health. You'll work with other youth and community organizations that use Native Hawaiian values to help you thrive.
Waianae, HawaiiAges 12–25 - NCT07534033RecruitingPhase 2
Probiotic LR607 for newly diagnosed lung cancer
This study tests whether a probiotic supplement (LR607) can help patients with newly diagnosed non-small cell lung cancer—a common type of lung cancer. Probiotics are beneficial bacteria that may help your immune system fight cancer alongside standard treatments.
GuangzhouAges 18–80 - NCT07535398Recruiting
Telehealth Exercise Program for High Lung Blood Pressure
This study tests whether people with elevated pressure in the blood vessels of the lungs can safely exercise at home using video sessions with therapists. It aims to see if remote rehabilitation can improve heart function and daily activity without requiring in-person visits.
Tokat ProvinceAges 18–65 - NCT07535437RecruitingPhase 1/Phase 2
New Drug Combination for Advanced Lung Cancer After Previous Treatment
This study tests a new combination of drugs (ivonescimab with either dato-DXd or osimertinib) for people with advanced lung cancer that has a specific EGFR gene mutation and has already been treated with other therapies. The goal is to see if this combination can help control the cancer better than current options.
Basking Ridge, New JerseyAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,347 recruiting pulmonology studies from the U.S. registry right now, out of 9,965 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.