Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 7,779 recruiting studies in this area right now.
By phase
- Not applicable6,422
- Phase 2492
- Phase 1250
- Phase 3240
- Phase 4212
- Phase 1/Phase 294
- Phase 2/Phase 369
Top conditions
- Anxiety387
- Depression382
- Alzheimer Disease338
- Autism Spectrum Disorder239
- Dementia228
- Mild Cognitive Impairment198
- Schizophrenia184
- Major Depressive Disorder173
- Insomnia159
- Cognitive Impairment150
- Alcohol Use Disorder145
- Opioid Use Disorder143
- Stress117
- PTSD105
- Mental Health99
- Autism94
- Mild Cognitive Impairment (MCI)89
- Suicidal Ideation89
Leading sponsors
- VA Office of Research and Development104
- Yale University87
- Massachusetts General Hospital77
- Stanford University68
- Assistance Publique - Hôpitaux de Paris64
- Johns Hopkins University62
- University of California, Los Angeles58
- University of Pennsylvania53
- Karolinska Institutet51
- The University of Hong Kong51
Where studies are running
- California520
- Massachusetts267
- New York255
- Texas209
- Maryland176
- Pennsylvania170
- Florida149
- Alabama118
- Arizona109
- Illinois104
Recruiting studies7,779 total
- NCT04883255RecruitingEarly Phase 1
Study cannabis effects on brain function in adults with HIV
This early-phase study looks at how cannabis (and the body’s cannabinoid system) may affect thinking and brain-related measures in people with HIV. You may be asked to avoid cannabis and complete several brain and health assessments to see how these factors relate.
San Diego, CaliforniaAges 18–65 - NCT04896775Recruiting
Online program to improve sleep for dementia caregivers
This trial tests a web-based program (NiteCAPP) to help people who care for someone with dementia sleep better. It targets caregivers with ongoing insomnia, and aims to improve sleep and daytime functioning.
Tampa, FloridaAges 18 years+ - NCT04887116RecruitingEarly Phase 1
Virtual reality sessions to treat PTSD in healthcare workers
This early-phase study tests whether guided virtual reality experiences can reduce symptoms of PTSD (post-traumatic stress disorder) or near-PTSD in healthcare workers. It may help people who have stress reactions related to work during the COVID-19 era.
New York, New YorkAges 18 years+ - NCT04877093RecruitingPhase 3
Low-dose clonidine for PTSD nightmares in veterans
This Phase 3 study tests whether low-dose clonidine can reduce PTSD symptoms and especially nightmares in U.S. veterans. You’d be screened for PTSD severity and current treatments, then asked to visit the clinic as scheduled to see if the treatment helps.
Wauwatosa, WisconsinAges 18 years+ - NCT04875936Recruiting
Neurofeedback therapy to improve reading after recent stroke
This trial studies whether a brain-training approach called neurofeedback can improve reading skills after a stroke that happened recently. It may help if you have clear reading and comprehension problems following a left-side stroke.
West Orange, New JerseyAges 18–80 - NCT04899687RecruitingPhase 2
Dextromethorphan for OCD and related anxiety conditions
This trial studies dextromethorphan, a medicine sometimes used for cough, to see if it can reduce symptoms in OCD and similar conditions. It may help people whose intrusive thoughts or related worries are still challenging despite current care.
Stanford, CaliforniaAges 18–65 - NCT04897334Recruiting
Brain stimulation plus rehab to improve thinking after stroke
This study tests whether a noninvasive brain stimulation treatment, combined with rehabilitation, can improve thinking and other “neurocognition” problems after a recent stroke. It may help people whose thinking has been affected by stroke within the past month.
Philadelphia, PennsylvaniaAges 18–90 - NCT04916340Recruiting
Exercise program study for heart blood vessel function and anxiety
This study tests whether an exercise training program can improve how well blood vessels work in people with PTSD or generalized anxiety. You may be placed into a PTSD, GAD, or healthy control group based on questionnaire scores.
Richmond, VirginiaAges 18–35 - NCT04916210Recruiting
Study how stroke type affects thinking and recovery
This study looks at what predicts memory and thinking problems after different types of stroke or brain bleeding, and how blood-vessel changes relate to recovery. You may be invited if you recently had a stroke/bleed and can complete a baseline check within 6 weeks.
Phoenix, ArizonaAges 18 years+ - NCT04899544Recruiting
Center vs home therapy for autism with PRT coaching
This study compares two ways of delivering Pivotal Response Treatment (PRT) for young children with autism—at a center or in the home. It may help your child by testing which approach better supports language and autism-related communication skills.
Stanford, CaliforniaAges 2–5 - NCT04906863Recruiting
Genetic study for early dementia in adults and families
This trial studies genes to better understand why some people develop dementia and memory problems earlier in life. It may help researchers find clearer causes and improve future testing and treatments for families affected by dementia.
New York, New YorkAges 35 years+ - NCT04902703RecruitingPhase 2
GM-CSF drug trial for mild to moderate Alzheimer’s disease
This Phase 2 study tests whether sargramostim (a GM-CSF related medicine) is safe and can slow or improve Alzheimer’s symptoms. You might be a good fit if you have mild or moderate Alzheimer’s, positive amyloid testing, and can complete frequent visits with a close caregiver who knows you well.
Aurora, ColoradoAges 60–85 - NCT04918329Recruiting
Digestive symptom check-in study for adults
This study follows adults with long-lasting “functional” digestive symptoms as part of routine care. It may help researchers better understand these conditions and improve how they are managed.
RouenAges 18 years+ - NCT04923685Recruiting
Study looks at blood markers linked to childhood trauma and suicide risk
This study checks whether tiny genetic signals in blood (microRNAs) are linked to childhood maltreatment and thoughts or risk of suicide, especially in people with major depression. It may help researchers understand biological clues that could someday guide better care.
Birmingham, AlabamaAges 18–60 - NCT04903028Recruiting
Brain stimulation to help people quit smoking
This study tests whether a type of brain stimulation (rTMS) can help people stop smoking. It targets brain circuits involved in cravings, aiming to support quitting safely.
Charleston, South CarolinaAges 22–70 - NCT02604277Recruiting
Study of suicidal behavior in people with bipolar disorder
This study looks at suicidal thoughts or behaviors in people diagnosed with bipolar disorder. It may help researchers understand what leads to suicidal risk and how to better support safety and treatment.
Atlanta, GeorgiaAges 18–64 - NCT04829682Enrolling by invitation
ACT for Life to help people manage suicide risk
This trial tests whether “ACT for Life,” a structured therapy approach, can better support people who are currently hospitalized because of suicide risk. You may be placed in one of two study groups to compare the therapy options and see which helps most.
Aurora, ColoradoAges 18–89 - NCT04832295Recruiting
Photo-based conversations to improve well-being during stress
This trial tests a structured, photo-based conversation approach to help people experiencing stress-related problems and who are currently on sick leave or at risk of needing sick leave. It may help you manage stress and improve well-being, but it also checks whether questions can be completed safely and accurately.
VaxjoAges 20–67 - NCT04798274Recruiting
Brain wiring study in autism using safe hearing tasks
This study looks at how a brain chemical related to calming signals (“GABA”) may affect how people process sounds in autism. The goal is to understand brain function during hearing tasks, which could help guide future treatments.
Bethesda, MarylandAges 11–25 - NCT04411225RecruitingPhase 3
CBD may help early psychosis along with usual treatment
This Phase 3 trial tests whether taking cannabidiol (CBD) can reduce symptoms when added to standard care for early psychosis (like first-episode psychosis or attenuated psychosis). It may help some people have fewer troubling thoughts or perceptions over time.
La Jolla, CaliforniaAges 16–30 - NCT04789148RecruitingPhase 1
Nasal oxytocin trial for people with hormone deficiency
This early-phase study tests whether a spray of oxytocin in the nose can be given safely and may affect symptoms in people with arginine-vasopressin deficiency. You might qualify if your hormone levels are stable and you can safely take the nasal study medicine during the study period.
Boston, MassachusettsAges 18 years+ - NCT04810624Recruiting
Online relapse prevention program for anorexia recovery habits
This study looks at how to help people with anorexia nervosa prevent relapse by changing habits, using video visits. It may help you stay stable after weight restoration and reduce the chance of returning to eating disorder symptoms.
New York, New YorkAges 18–60 - NCT04832568Recruiting
EEG monitoring to predict and prevent postoperative delirium
This study checks brain-wave signals during heart surgery (using EEG monitoring) to understand who is at risk for confusion after surgery. If you qualify, your team will track your thinking after the operation to help reduce or better manage postoperative delirium.
Wuhan, HubeiAges 18 years+ - NCT04797455Recruiting
Parent program for teens in inpatient mental health care
This study tests an intervention (a structured parent-focused program) for parents of teens who are currently hospitalized for suicidal thoughts or a suicide attempt. It may help families learn ways to support their teen during and after hospitalization.
Stanford, CaliforniaAges 12–85
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 7,779 recruiting psychiatry studies from the U.S. registry right now, out of 12,461 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.