Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,575 recruiting studies in this area right now.
By phase
- Not applicable2,950
- Phase 4240
- Phase 2131
- Phase 3102
- Phase 193
- Phase 2/Phase 337
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University84
- Cairo University59
- Beijing Tiantan Hospital34
- Tanta University33
- Ain Shams University28
- Foundation University Islamabad28
- Mayo Clinic25
- VA Office of Research and Development23
- Hacettepe University22
- Stanford University20
Where studies are running
- California151
- New York79
- Massachusetts65
- Florida64
- Texas51
- Illinois40
- North Carolina40
- Maryland39
- Ohio39
- Minnesota37
Recruiting studies3,575 total
- NCT07627750Recruiting
Low-dose muscle relaxant for spine surgery monitoring
This study tests whether a low dose of a muscle relaxant called rocuronium is safe and effective during spine surgery when doctors are monitoring the nerves. This may help patients who need spine surgery with nerve monitoring.
Hanoi, HanoiAges 18 years+ - NCT07877948Recruiting
Combination therapy for diabetic nerve pain and foot ulcers
This study tests whether a treatment called Bionerv E+ helps with nerve pain and healing of foot ulcers in people with type 2 diabetes, compared with a standard vitamin B complex. If you have diabetes-related nerve damage and a foot ulcer that is not too severe, this study might help you understand if this new option works.
Cheras, Kuala LumpurAges 18 years+ - NCT07878156RecruitingPhase 3
Numbing medicine for children having brain tumor surgery
This study tests whether adding a numbing medicine to the standard pain block can reduce pain after brain surgery in children. It may help children feel more comfortable and recover more smoothly.
CairoAges Up to 18 years - NCT07877376Recruiting
How thinking problems affect pain in breast cancer survivors
This study looks at whether mild memory or thinking issues after breast cancer treatment are linked to ongoing pain. If you join, you will help doctors understand this connection, which may lead to better pain care.
Boulogne-Billancourt, IDEAges 35–65 - NCT07602595Recruiting
Early-life health risks and chronic pain in teens and young adults
This study looks at how early health problems might affect pain that lasts a long time. If you had a muscle or joint surgery, or a rheumatic disease, before age 18, you might help us understand why some people get ongoing pain.
Cincinnati, OhioAges 14–26 - NCT07878533RecruitingPhase 2
Ear surgery pain relief with added medication
This study tests whether adding a sedative medicine to the numbing shot around the ear nerve can improve pain control during and after middle ear surgery. It aims to make the procedure more comfortable and reduce the need for strong painkillers.
MinyaAges 18–70 - NCT03427736Recruiting
Anesthetics and pain medicines study for children
This study looks at how children process certain anesthetics and pain medicines. It aims to find the best doses for safety and effectiveness.
Stanford, CaliforniaAges 6 months–17 years - NCT07786012RecruitingPhase 4
Buprenorphine vs. morphine for pain relief after C-section
This study compares two pain medications given after a planned C-section to see which works better. If you are having a planned C-section, this trial may help you find better pain control.
New York, New YorkAges 19 years+ - NCT07210515RecruitingPhase 3
Testing Ambros Therapy for Early CRPS
This trial tests if an intravenous medicine called AMBTX-01 (neridronate) can help people with early-stage Complex Regional Pain Syndrome (CRPS) type 1. It focuses on those whose affected limb feels warm, looks red, and is swollen.
Phoenix, ArizonaAges 18 years+ - NCT07533383Recruiting
Pain relief block for inguinal hernia surgery
This trial tests a numbing injection near the hip to reduce pain after inguinal hernia repair. It may help you feel more comfortable and satisfied with your recovery.
SanliurfaAges 18–65 - NCT07397715Recruiting
Ultrasound signs of adenomyosis and related symptoms
This study uses ultrasound to look for signs of adenomyosis (a condition where the uterine lining grows into the muscle wall) and see how those signs relate to symptoms. It may help doctors better diagnose and treat the condition.
LeuvenAges 18 years+ - NCT06168058Recruiting
Pelvic vein embolization for chronic pelvic pain
This trial tests if blocking enlarged veins in the pelvis (called embolization) can reduce long-term pelvic pain that hasn't improved with other treatments. It may help women whose pain is worse when standing or walking and better when lying down.
Kansas City, KansasAges 18–75 - NCT07855341RecruitingPhase 4
Nerve block study for hip replacement pain relief
This study tests two different amounts of a numbing medicine injected around the hip nerves before hip replacement surgery, to see if adding a steroid helps reduce pain after surgery. It aims to improve pain control and recovery.
Cairo, Cairo GovernorateAges 50–70 - NCT07786415Recruiting
Posture and physical function in college students with upper cross syndrome
This study looks at how posture affects everyday function in people with a common muscle imbalance called upper cross syndrome. It may help you understand your condition better, but you must be a college student in a specific age range and have this posture issue.
CairoAges 20–29 - NCT05492188Recruiting
Testing training and skin reflex changes for nerve pain after SCI
This study looks at how a training program affects skin reflexes and nerve pain in people with spinal cord injury (SCI). It may help researchers find better ways to manage nerve pain by changing how the body responds to touch and training.
Charleston, South CarolinaAges 18 years+ - NCT07857733RecruitingPhase 3
Extended treatment study for complex regional pain syndrome
This study gives an extended course of neridronate infusions to people who completed the earlier AMBTX-01-301 trial, to see if longer treatment safely keeps easing their chronic pain and other symptoms of complex regional pain syndrome (a long-lasting pain condition, often after an injury).
Phoenix, ArizonaAges 18 years+ - NCT04128670Recruiting
Kinesio tape test for sore muscles after exercise
This study checks whether Kinesio tape changes how sore your muscles feel after workouts. You may help researchers learn if the tape reduces “delayed onset muscle soreness” after upper-body activity.
Indianapolis, IndianaAges 18–30 - NCT07582029Recruiting
Comparing two pain relief methods for gallbladder surgery
This study compares two ways of giving pain relief after gallbladder removal surgery: an injection of numbing medicine around the belly muscles (guided by ultrasound) versus a simple injection into the skin near the surgery cuts. The goal is to see which method provides better pain control and comfort after surgery.
IstanbulAges 18 years+ - NCT07843212Recruiting
Nerve block for breast cancer surgery
This study tests a nerve block (called SPSIP) given during breast cancer surgery to see if it reduces inflammation and affects a protein called TLR4, which may help with pain and recovery. If you're having breast cancer surgery, this might help you heal better with less discomfort.
Çorum, ÇorumAges 18–85 - NCT04965675RecruitingPhase 3
Eptinezumab for teens with chronic migraine
This trial tests eptinezumab, a preventive medicine, to reduce headache frequency in teens with chronic migraine. It may help your teen if they have frequent migraine days despite usual care.
New Haven, ConnecticutAges 12–17 - NCT07393503Enrolling by invitationPhase 4
Pain relief for new muscle and joint injuries
This trial compares two common treatments for new muscle or joint pain: an over-the-counter pain reliever (Tylenol and ibuprofen) versus an oral steroid (a stronger anti-inflammatory medication). The goal is to see which option works better for short-term pain and recovery.
Buffalo, New YorkAges 18 years+ - NCT07777172Recruiting
Pain relief injections for gallbladder surgery
This trial tests two types of numbing injections (nerve blocks) around the ribs and abdomen to see if they reduce pain after laparoscopic gallbladder removal surgery. It may help you have better pain control and a smoother recovery.
Ankara, Yenimahalle\AnkaraAges 18–75 - NCT07674654RecruitingPhase 3
Long-term safety study of an investigational migraine medication
This study is testing the long-term safety of an investigational migraine medication called elismetrep. It is for people who have already completed a previous study of this drug and are willing to continue using a smartphone app to track their symptoms daily.
Birmingham, AlabamaAges 18 years+ - NCT07403331Recruiting
Nerve pain in legs: spinal cord stimulation plus team care
This trial tests a treatment bundle that combines a spinal cord stimulator (a device that sends mild electrical pulses to your spine to block pain signals) with a team of specialists (like a psychologist and physical therapist) to reduce chronic nerve pain in the legs and improve your ability to move and function.
OsloAges 18–60
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,575 recruiting pain medicine studies from the U.S. registry right now, out of 6,452 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.