Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,752 recruiting studies in this area right now.
By phase
- Not applicable3,096
- Phase 4253
- Phase 2145
- Phase 3104
- Phase 197
- Phase 2/Phase 335
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University96
- Cairo University62
- Beijing Tiantan Hospital34
- Ain Shams University31
- Mayo Clinic28
- Tanta University28
- Foundation University Islamabad26
- Stanford University24
- VA Office of Research and Development22
- Hacettepe University20
Where studies are running
- California160
- New York81
- Massachusetts68
- Florida63
- Texas51
- Ohio47
- Maryland42
- Minnesota42
- Illinois38
- North Carolina38
Recruiting studies3,751 total
- NCT00001373Recruiting
Understanding the genetics of autoinflammatory diseases
This study collects genetic samples and medical histories from people with autoinflammatory diseases (like Familial Mediterranean Fever), their relatives, and healthy volunteers to understand how these conditions run in families and what causes them. Participation mainly involves providing a mail-in DNA sample.
Washington D.C., District of ColumbiaAges 2 months–115 years - NCT06909513Enrolling by invitation
Can a travel neck pillow help after thyroid surgery?
This study tests if using a travel neck pillow after thyroid surgery improves neck comfort and movement. It may help you recover more easily if you are having your thyroid removed.
Kayseri, TalasAges 18 years+ - NCT06691490Recruiting
Brain activity and daily physical activity study
This study looks at how your brain's perception of effort is linked to how much physical activity you do. It uses EEG (a cap that records brain waves) and fMRI (an MRI that shows brain activity) to understand this connection.
La TroncheAges Any age - NCT06648616Recruiting
Resistance band training for female footballers
This study tests if elastic band exercises can improve performance in women football players. If you play in a top Portuguese league, you may be eligible.
Maia, Porto DistrictAges 18 years+ - NCT06101511Recruiting
Breathing tube pressure for safer abdominal surgery
This trial is testing if using less air pressure from the breathing machine during abdominal surgery can help prevent lung complications. If you are at higher risk for breathing problems after surgery, this study may help find a safer way to manage your breathing during the operation.
Amsterdam, NoordhollandAges 18–100 - NCT06004804Recruiting
Psychological treatments for chronic pain in veterans
This study compares two group psychological treatments for chronic pain delivered over video conference. It aims to see if these treatments help reduce pain and improve quality of life for veterans.
West Los Angeles, CaliforniaAges 60–95 - NCT07018375RecruitingPhase 4
Oliceridine for reducing chronic pain after lung surgery
This study tests whether a new pain medication (oliceridine) given through an IV patient-controlled pump can reduce chronic pain after lung surgery. Participants will receive either oliceridine or a standard opioid for pain control after a minimally invasive lung resection. The study will follow patients for several months to see if they develop long-term pain.
Baoding, HebeiAges 18–75 - NCT07793214Recruiting
Whole-body infrared hyperthermia for advanced solid tumors
This study looks at how well a treatment called whole-body infrared hyperthermia works for people with advanced solid tumors. The treatment uses heat to warm the whole body and may help fight cancer. The study will review medical records of people who already had this treatment at Zhejiang Hospital, and some people may join going forward.
Hangzhou, ZhejiangAges Any age - NCT05722002RecruitingPhase 4
Compare pain-med plans after low-risk surgery
This study tests which pain-medication plan works best and has the fewest side effects after certain low-risk surgeries. You may be assigned to receive opioid-based, NSAID-based, or acetaminophen-based pain control depending on your situation.
Ann Arbor, MichiganAges 18 years+ - NCT07719608Recruiting
MySalvia system for resistant migraine
This trial tests a device called MySalvia that is implanted in the head to reduce migraine attacks. It is for people whose migraines have not improved with at least three different preventive treatments.
Newnan, GeorgiaAges 22–84 - NCT07792044Enrolling by invitation
Pain relief after shoulder surgery
This study tests a numbing medicine injected near the shoulder to see if it gives better pain relief after arthroscopic shoulder surgery than the standard approach. It might help you recover with less pain and fewer side effects.
Jiaxing, ZhejiangAges 18 years+ - NCT07451769Recruiting
Testing a new drug target for migraine relief
This trial tests a substance that activates adrenomedullin receptors, which may be a new way to treat migraines. It may help people who have migraines without aura and aren't on preventive migraine medications.
Glostrup MunicipalityAges 18–65 - NCT06666985RecruitingPhase 4
Spinal morphine for pain relief after major abdominal surgery
This trial tests whether a single injection of morphine into the fluid around the spine can provide better pain relief after planned laparoscopic or robotic abdominal surgery. If you are having one of several types of major abdominal surgery that lasts at least 2 hours and requires a hospital stay of at least 1 day, this study may be an option.
Guangzhou, GuangdongAges 18 years+ - NCT06373978RecruitingPhase 4
Non-narcotic pain relief after elbow needle procedure
This study tests non-narcotic pain medicine after a needle procedure for chronic elbow tendon pain. It compares different pain-relief options to find what works best without opioids.
Coral Springs, FloridaAges 18–65 - NCT07191873RecruitingPhase 4
Tirzepatide for treating high pressure in the brain
This trial tests if tirzepatide can help lower the pressure inside your skull caused by a condition called Idiopathic Intracranial Hypertension. It's designed for people with a BMI of 30 or higher who have swelling of the optic nerve.
Durham, North CarolinaAges 18–60 - NCT07496099Recruiting
Comparing two muscle-release therapies for low back pain
This study compares two types of gentle muscle-release techniques—post-isometric relaxation and myofascial release—to see which better relieves low back pain caused by lower cross syndrome, a common muscle imbalance. If you have ongoing back pain and tight hamstrings, this trial may offer a drug-free treatment option.
Karachi, SindhAges 18–45 - NCT07628218Recruiting
Video versus in-person exercise training for heel pain
This trial compares two ways to learn exercises for plantar fasciitis (heel pain caused by tissue strain): watching instructional videos on your own versus attending sessions with a doctor or trainer. The goal is to see which method helps reduce pain and improve walking more effectively.
BalıkesirAges 18–70 - NCT06058169RecruitingTeam says not enrolling
Home vibration therapy for arthritis knee pain
This study tests if doing whole-body vibration exercises at home can help reduce knee pain from arthritis. You stand on a gently vibrating platform for short periods over several weeks.
Augusta, GeorgiaAges 40–75 - NCT07308834RecruitingPhase 1/Phase 2
Knee injection study for moderate to severe osteoarthritis pain
This study tests a new knee injection called CX-011 to see if it can reduce pain and improve function in people with knee osteoarthritis. It may be a good option if you have tried other treatments without enough relief.
Los Angeles, CaliforniaAges 40–75 - NCT07790874Recruiting
Eye exercises for neck-related dizziness
This trial tests whether eye exercises can help reduce dizziness and neck pain in people with chronic neck-related dizziness that started without an injury. It may help you if your dizziness has lasted for at least 3 months and is linked to your neck.
Faisalābad, Punjab ProvinceAges 20–40 - NCT07755540RecruitingPhase 2
Group music therapy for chronic pain in active duty service members
This study tests whether participating in group music therapy sessions can help active duty service members manage chronic pain. It aims to see if music therapy can improve pain symptoms and quality of life.
Anchorage, AlaskaAges 18–64 - NCT07791355Recruiting
Testing pain reprocessing therapy for chronic pain
This study tests a psychological treatment called Pain Reprocessing Therapy (PRT) for people with chronic primary pain like fibromyalgia or back pain. It aims to see if this treatment is feasible and helpful in a specialist pain clinic.
StockholmAges 18 years+ - NCT07789301Recruiting
Predicting severe pain after planned cesarean with spinal anesthesia
This study looks at how to predict severe pain after a planned cesarean delivery done under spinal anesthesia. It aims to find factors that may help doctors better manage pain after surgery.
Bursa, NilüferAges 18–45 - NCT07790471Recruiting
Recovery checklists after cesarean delivery
This study looks at how following a recovery plan after a planned cesarean birth affects how well mothers feel and recover. It involves filling out questionnaires before and after the surgery to track your recovery.
Bursa, NilüferAges 18 years+
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,752 recruiting pain medicine studies from the U.S. registry right now, out of 6,746 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.