Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,749 recruiting studies in this area right now.
By phase
- Not applicable3,095
- Phase 4251
- Phase 2145
- Phase 3104
- Phase 197
- Phase 2/Phase 335
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University96
- Cairo University62
- Beijing Tiantan Hospital34
- Ain Shams University32
- Tanta University30
- Foundation University Islamabad27
- Mayo Clinic26
- Stanford University24
- VA Office of Research and Development22
- Hacettepe University20
Where studies are running
- California158
- New York80
- Massachusetts68
- Florida65
- Texas52
- Ohio48
- Maryland42
- Minnesota41
- North Carolina38
- Illinois37
Recruiting studies3,748 total
- NCT06692335Recruiting
Comparing HIFU and surgery for uterine fibroids
This trial compares two treatments for painful or heavy menstrual bleeding caused by uterine fibroids: high-intensity focused ultrasound (HIFU) and myomectomy (surgery to remove fibroids). It may help you decide which option fits your needs.
Hong KongAges 18–50 - NCT06693063Recruiting
Follow-up after chest pain in emergency
This study looks at whether seeing your regular doctor after a hospital visit for chest pain can help prevent future emergency visits. If you had chest pain and went to the Emile Roux emergency room, you may be able to join.
Le Puy-en-VelayAges 18 years+ - NCT06693453Recruiting
Acupuncture plus cupping for lower back pain
This study tests whether combining electronic acupuncture with dry cupping helps relieve lower back pain caused by a spine condition. It is for people whose pain matches a traditional Chinese medicine pattern of stabbing, fixed pain that gets worse at night.
Ho Chi Minh CityAges 18–70 - NCT06693479Recruiting
Using a feedback device to help manage shoulder pain at work
This study tests whether a feedback device can help people with work-related shoulder pain manage their symptoms. You may qualify if you have shoulder pain from rotator cuff issues, arthritis, or rheumatoid arthritis and work full-time.
Québec, QuebecAges 18 years+ - NCT06694103Recruiting
Two ways to reduce pain during a baby's eye exam
This study tests two drug-free methods to help reduce pain when premature babies get a special eye exam for retinopathy of prematurity. It may help your baby feel more comfortable during the procedure.
Izmir, MenemenAges 6 months–8 months - NCT06696300Recruiting
Breathing muscle training for chronic low back pain
This study tests whether training the muscles you use to breathe can help reduce chronic low back pain. You will practice specific breathing exercises and see if they improve your pain and function.
Kırşehir, CenterAges 18–65 - NCT06696898Recruiting
Stretching with and without muscle release for sciatica
This study tests if adding myofascial release (a type of hands-on therapy for tight muscles) to a standard self-stretching program helps relieve sciatica pain and improve movement. It's for people with long-standing (chronic) one-sided sciatica.
Lahore, Punjab ProvinceAges 25–50 - NCT06697457Recruiting
Comparing exercises for chronic neck pain
This trial tests different types of exercise to see which works best for people with long-lasting neck pain. You may join if your neck pain has lasted at least 3 months and is at least a 5 out of 10 in intensity.
Muğla, MenteşeAges 18–55 - NCT06702176Recruiting
Testing a multisite TENS suit for fibromyalgia symptoms
This trial tests a special suit that uses gentle electrical pulses to help reduce fibromyalgia pain and other symptoms. If you qualify, you might find new relief for your fibromyalgia.
Créteil, VAL DE MARNEAges 18–75 - NCT06702189Recruiting
EXOPULSE Mollii Suit for low back pain
This trial tests a special suit (EXOPULSE Mollii) to see if it helps relieve low back pain. It may be an option if you've had back pain for at least 3 months and are not planning surgery.
Créteil, VAL DE MarneAges 18–75 - NCT06702904Recruiting
Neuroprosthesis for phantom limb pain relief
This study tests a new type of artificial limb (neuroprosthesis) that sends signals back to your brain to help reduce phantom limb pain and improve your daily life. You may be able to join if you have had an arm or leg amputation at least 6 months ago and have persistent pain.
MoscowAges 18–65 - NCT06704061Recruiting
Online yoga vs ACT for chronic pain in veterans
This study compares online yoga with Acceptance and Commitment Therapy (ACT), a type of talk therapy, to see which helps veterans better manage long-lasting muscle or bone pain. You can join from home through the internet.
Palo Alto, CaliforniaAges 18 years+ - NCT06704490Recruiting
Chronic pain after planned cesarean section
This study looks at how common chronic pain is after a planned cesarean section and what factors might increase that risk. It could help doctors better prevent and manage long-term pain after delivery.
Wuhan, HubeiAges 20–50 - NCT06705751Recruiting
Faster diagnosis of abnormal coronary artery origin
This study tests a new, faster way to diagnose an uncommon heart condition where one of the main arteries (the coronary artery) starts from the wrong place on the aorta. The goal is to help doctors find and treat it sooner.
San Donato Milanese, ItaliaAges 6 years+ - NCT06705881Recruiting
Shock wave therapy for athletes with jumper's knee
This trial tests if extracorporeal shock wave therapy (a non-surgical treatment using sound waves) can help athletes with patellar tendinopathy, also known as jumper's knee. It is for people who have had pain in the patellar tendon for at least 6 months and are active in jumping sports.
Kırşehir, CenterAges 18–65 - NCT06706037Recruiting
Reformer exercise for chronic muscle and joint pain
This study tests if Reformer Pilates exercises can reduce pain for people with long-term muscle or joint pain. It may help you feel better and move more easily.
Ankara, Select StateAges 30–50 - NCT06707805Recruiting
Spinal gliding technique for lower cross syndrome
This trial tests a manual therapy technique called sustained natural apophyseal glides (gentle, sustained pressure on the spine) in people with low back pain caused by lower cross syndrome—a pattern where hip flexors and lower back muscles are tight while abs and buttock muscles are weak. If you have lower back pain with a forward-tilted pelvis and meet the age and muscle tightness/weakness criteria, this study may be for you.
Kotli, Azad KashmirAges 30–50 - NCT06707532Recruiting
Muscle relaxants for safer heart rhythm treatment
This study tests if giving muscle relaxants before a heart ablation procedure can protect muscles from damage. Ablation uses energy to fix irregular heartbeats, and muscle relaxants might make it safer.
Wroclaw, Lower Silesian VoivodeshipAges 18–90 - NCT06008795RecruitingPhase 2
Pain-block injection for headache after brain bleed
This study tests a pain-block injection (called a PPF-block) for severe headaches after a brain bleed (subarachnoid hemorrhage). It compares the injection to standard pain medicine to see if it reduces headache and the need for opioids.
Gainesville, FloridaAges 18–85 - NCT06275698Recruiting
Honey for pain relief after tonsil removal
This trial tests whether taking honey after tonsil surgery helps reduce pain. If you are having both tonsils removed and are over 18, you may be able to join.
StevenageAges 18 years+ - NCT06284278Recruiting
Telehealth exercise for postpartum pelvic pain
This study compares two types of exercise done at home through telehealth sessions to see which better reduces pelvic pain after pregnancy. It may help you if you have ongoing pain in your lower back or pelvic area that started during pregnancy or after childbirth.
Tainan, TaiwanAges 20–65 - NCT07685340Recruiting
Cupping vs Massage Tool for Chronic Low Back Pain
This trial tests two hands-on therapies—dry cupping and a special massage technique—to see which works better for long-term low back pain caused by muscle knots. You may be able to join if your pain has lasted over 3 months and you have trigger points.
Rawalpindi, Punjab ProvinceAges 25–45 - NCT06664177Recruiting
Pain block comparison for hernia surgery
This trial compares two nerve-block techniques (Quadratus Lumborum block vs. Transversalis Fascia block) to control pain after inguinal hernia surgery. It aims to find which method provides better pain relief and recovery.
IstanbulAges 18–65 - NCT06082206Recruiting
Nerve blocks to prevent long-term pain after breast cancer surgery
This study compares two types of nerve blocks (pectoral nerve block vs. paravertebral block) to see which one better prevents long-term pain after breast cancer surgery.
AsyutAges 20–65
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,749 recruiting pain medicine studies from the U.S. registry right now, out of 6,811 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.