Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,749 recruiting studies in this area right now.
By phase
- Not applicable3,095
- Phase 4251
- Phase 2145
- Phase 3104
- Phase 197
- Phase 2/Phase 335
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University96
- Cairo University62
- Beijing Tiantan Hospital34
- Ain Shams University32
- Tanta University30
- Foundation University Islamabad27
- Mayo Clinic26
- Stanford University24
- VA Office of Research and Development22
- Hacettepe University20
Where studies are running
- California158
- New York80
- Massachusetts68
- Florida65
- Texas52
- Ohio48
- Maryland42
- Minnesota41
- North Carolina38
- Illinois37
Recruiting studies3,748 total
- NCT06668415Recruiting
Spencer technique after hydrodilation for frozen shoulder
This trial tests if adding a gentle hands-on treatment (Spencer technique) to the standard fluid injection procedure (hydrodilation) helps people with frozen shoulder move more easily and feel better. If you have been diagnosed with unilateral frozen shoulder and have already had the hydrodilation procedure, you may qualify.
Rawalpindi, Punjab ProvinceAges 40–65 - NCT06668623Recruiting
Reiki for nerve pain and sleep in diabetic neuropathy
This trial tests if Reiki, a gentle hands-on energy therapy, can reduce nerve pain and improve sleep in people with diabetic neuropathy. It may offer a non-drug option for managing symptoms.
Kayseri, KocasinanAges 18–70 - NCT06669884Recruiting
New ECG method to quickly sort chest pain in ER
This study tests a new ECG-based technology that may help doctors more quickly sort out the cause of your chest pain in the emergency room. If you have chest pain that needs checking, this tool could help decide how urgent your care is.
Jinan, ShandongAges 18 years+ - NCT06670053Recruiting
Testosterone and brain development in teens
This study looks at how starting testosterone therapy affects brain development in transgender and gender-diverse youth. It may help you and your doctor understand the changes to expect.
Aurora, ColoradoAges 12–20 - NCT06670768Recruiting
Comparing two heart imaging tests for blocked arteries
This trial compares two heart imaging tests (SPECT and coronary CTA) to see if a newer method gives a clearer picture of blood flow. If you have been referred for one of these tests, you may be able to help by also having the other test done at no extra risk.
Budapest, BudapestAges 18 years+ - NCT06671002RecruitingPhase 4
Pain medicine safety study for kids having surgery
This study compares different pain medicines to see which works best and is safest for children after surgery for tonsil removal, gallbladder removal, or knee arthroscopy. It aims to help find the most effective and least risky pain control option.
Los Angeles, CaliforniaAges 12–20 - NCT06671132RecruitingPhase 2
Computer training for pain relief using smell exercises
This trial tests a computer program that uses smell training to help people with chronic low back pain. It aims to reduce pain by retraining brain connections.
Washington D.C., District of ColumbiaAges 18–85 - NCT06671665Recruiting
Manual therapy for low back pain in women with osteopenia
This study tests if manual therapy (hands-on treatment by a therapist) can reduce low back pain in postmenopausal women who have osteopenia, a condition where bones are weaker than normal but not yet osteoporosis. It aims to help with pain located in the lower back area.
GizaAges 50–60 - NCT06674707Recruiting
Agility training with foot exercises for kneecap pain
This trial tests whether adding foot exercises to agility training can better relieve long-lasting knee pain (patellofemoral pain syndrome) in adults ages 20 to 40. Eligible participants will have had pain behind the kneecap for over 6 months.
Lahore, Punjab ProvinceAges 20–40 - NCT06674772Recruiting
Migraine study measuring CGRP levels by age and sex
This study measures a substance called CGRP in saliva from people with migraine and healthy volunteers to see how it changes with age and sex. It may help researchers understand migraine better.
Barcelona, BarcelonaAges 6–75 - NCT06675877Recruiting
Virtual reality for kids with kidney disease on dialysis
This study tests whether virtual reality (VR) can help reduce anxiety and depression in children with end-stage kidney disease who are on hemodialysis through an arteriovenous fistula. It may offer a fun, drug-free way to feel better during treatment.
TantaAges 8–18 - NCT06677606Recruiting
Nerve block vs anesthetic infiltration for hip surgery
This trial compares two ways to manage pain after hip replacement surgery: a nerve block (PENG block) versus injecting anesthetic near the hip. The goal is to see which provides better pain relief.
Al FayyumAges 50–90 - NCT06679205Recruiting
Multidisciplinary care for long-term low back pain
This study tests a team-based, non-drug treatment program for long-term low back pain. It combines physical therapy, education, and support to help reduce pain and improve daily function.
Barcelona, BarcelonaAges 18 years+ - NCT06684249Recruiting
Comparing nerve block and Botox for chronic migraine
This study compares two treatments for chronic migraine: a nerve block (injection near the nerves in the head) and Botox injections. It aims to see which one works better to reduce headache days and improve quality of life.
Zagazig, Sharqia ProvinceAges 18–65 - NCT06684275Recruiting
Radiofrequency treatment comparison for trigeminal neuralgia pain
This trial compares two types of radiofrequency treatment (pulsed and thermal) to see which works better for people with trigeminal neuralgia, a condition that causes severe, stabbing facial pain. If you have had facial pain for at least six months that isn't controlled by medicine, this study may help you find relief.
Zagazig, Sharqia ProvinceAges 18–60 - NCT06684587Recruiting
Telehealth exercise and mindfulness for knee osteoarthritis pain
This study tests whether a telehealth program combining exercise and mindfulness can help reduce knee pain from osteoarthritis. It is designed for people who have had knee pain for at least 3 months and can attend sessions remotely.
Boston, MassachusettsAges 50 years+ - NCT06685094Recruiting
Pain, movement, and quality of life study for Albanian speakers
This study is translating health questionnaires into Albanian to better understand pain, movement, mood, and quality of life. It aims to help people with muscle, joint, or back pain.
Murcia, MurciaAges 18–80 - NCT06685107Recruiting
Virtual reality for pain relief in older ER patients
This trial tests if using virtual reality along with standard pain medication helps reduce pain better than medication alone for older adults with muscle or joint pain in the emergency room.
Brooklyn, New YorkAges 65–120 - NCT06686290Recruiting
Stretching exercises for levator scapulae pain
This trial compares two stretching techniques to relieve chronic neck and shoulder blade pain caused by tight levator scapulae muscles. It may help you if you have had this pain for at least 3 months and have trouble turning or tilting your head.
Daska Kalan, Punjab ProvinceAges 24–59 - NCT06686147Recruiting
AI analysis of movement in low back pain
This trial uses artificial intelligence to analyze how well you can move if you have chronic low back pain. It may help researchers understand movement patterns better.
DenizliAges 18–65 - NCT06687018Recruiting
Comparing two hand therapies for carpal tunnel relief
This study tests two types of gentle hand and wrist movements (mobilizations) to see which better relieves pain, tingling, and numbness in carpal tunnel syndrome. It may help you if you have these symptoms and are otherwise healthy.
Lahore, Punjab ProvinceAges 20–45 - NCT06688864Recruiting
App-based support for chronic pain in underserved adults
This study tests a smartphone app (EPIO) to help people with chronic pain manage their daily life. It is designed for adults who are Black and/or LGBTQ+ and face added challenges because of limited resources.
Rochester, MinnesotaAges 18 years+ - NCT06690060Recruiting
Mind-body program for chronic migraine
This study tests whether a mind-body program, done remotely, can help people with chronic migraines reduce headache impact. It is for adults who have migraines at least 5 days a month and are willing to learn relaxation and stress-management techniques.
Boston, MassachusettsAges 18 years+ - NCT06691750Recruiting
Barbed Suture Study for Cesarean Wound Healing
This trial tests if a special type of stitch (barbed suture) used to repair the uterus during cesarean section can reduce the chance of developing a small pocket or gap in the uterine scar, called isthmocele. If you are having a planned or emergency c-section at Hospital Clinic of Barcelona, you may be able to join.
BarcelonaAges 18 years+
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,749 recruiting pain medicine studies from the U.S. registry right now, out of 6,811 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.