Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,764 recruiting studies in this area right now.
By phase
- Not applicable3,111
- Phase 4251
- Phase 2144
- Phase 3104
- Phase 197
- Phase 2/Phase 335
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University97
- Cairo University62
- Beijing Tiantan Hospital34
- Ain Shams University32
- Tanta University30
- Foundation University Islamabad26
- Mayo Clinic26
- Stanford University24
- VA Office of Research and Development22
- Hacettepe University20
Where studies are running
- California158
- New York80
- Massachusetts68
- Florida65
- Texas52
- Ohio48
- Maryland42
- Minnesota41
- Illinois38
- North Carolina38
Recruiting studies3,763 total
- NCT07418944Recruiting
Surgery vs. non-surgery for leg pain from a slipped disc
This trial compares surgery to non-surgical treatments for people with leg pain caused by a lumbar disc herniation (slipped disc). It tests if surgery provides better relief after at least 6 weeks of symptoms.
HelsinkiAges 18–60 - NCT07420192Recruiting
A study on nerve surgery for pain after leg amputation
This trial tests a surgery called RPNI to treat painful nerve growths (neuromas) in people who have lost a leg. The goal is to reduce severe pain and improve the ability to use a prosthetic limb.
Ankara, AnkaraAges 18–70 - NCT07420712Recruiting
A Nerve Block for Minimally Invasive Heart Surgery
This study tests a pain-relieving nerve block for the back (serratus posterior superior plane block) given before minimally invasive heart bypass surgery. It aims to see if this block helps with pain control and recovery after surgery.
IstanbulAges 18–75 - NCT07423377Recruiting
Vibration device for fibromyalgia pain
This trial tests if a device that delivers small vibrations to your ear can help reduce pain from fibromyalgia. You'll use the device as directed and answer online questions about your pain before and after.
New York, New YorkAges 18 years+ - NCT07424209Recruiting
Hypnotic communication during heart catheterization study
This study tests whether talking in a special relaxed way (hypnotic communication) during a heart procedure can help you feel calmer and more comfortable. You may be able to join if you are at least 18, can understand Italian, and are already scheduled for a coronary angiogram.
Ponderano, ItalyAges 18 years+ - NCT07424638Recruiting
Nerve blocks for shoulder pain after lung surgery
This trial compares two types of nerve blocks to prevent shoulder pain after lung cancer surgery. If you are having open-lung surgery for lung cancer, you may be able to join.
CairoAges 18–65 - NCT07425457Recruiting
Cold nerve treatment before knee replacement surgery
This trial tests a cold therapy on nerves before knee replacement to reduce pain. It may help you recover with less discomfort after surgery.
AthensAges 18 years+ - NCT07427862Recruiting
Virtual reality for kids having interventional radiology
This study tests if using virtual reality (VR) during interventional radiology procedures can help children feel more comfortable and less anxious. It is looking for children ages 8 and older who are in the normal range of development.
Los Angeles, CaliforniaAges 8 years+ - NCT07428811Recruiting
Mirror therapy for post-stroke shoulder and hand problems
This trial tests whether task-based mirror therapy can help improve shoulder and hand function in people who have had a stroke less than 6 months ago. It focuses on those with moderate to severe stroke symptoms but without severe muscle stiffness or cognitive issues.
Lahore, Punjab ProvinceAges 45–75 - NCT07429669Recruiting
Comparing shoulder nerve blocks for pain and breathing
This study compares two different shoulder nerve blocks to see which one provides better pain relief after shoulder surgery while also checking how they affect your breathing. If you are having a shoulder arthroscopy, you may be eligible to help find the safest and most effective pain control option.
Yenimahalle, AnkaraAges 18–65 - NCT07429916RecruitingEarly Phase 1
Ketamine for shoulder pain after weight loss surgery
This trial tests if a single dose of ketamine, given during surgery, can reduce common shoulder pain after laparoscopic gastric sleeve surgery. If you are having this weight-loss procedure and meet the weight and health criteria, this study may help improve your recovery.
IrbidAges 18–60 - NCT07431632Recruiting
Nerve freezing vs. epidural for pain after pectus excavatum repair
This study compares two ways to manage pain after pectus excavatum surgery: freezing the nerves during surgery (cryoanalgesia) versus an epidural block. The goal is to see which method provides better pain relief with fewer side effects.
São Paulo, São PauloAges 13 years+ - NCT07431892Recruiting
Pain after robotic vs. laparoscopic colon cancer surgery
This study compares pain levels after two types of minimally invasive colon cancer surgery: robotic and laparoscopic. It aims to see if one approach leads to less pain, which may help you recover more comfortably.
MadridAges 18 years+ - NCT07432425Recruiting
Exercise programs for chronic neck pain
This study compares different exercise programs to see which one improves physical and mental health in people with chronic neck pain. You may be eligible if you have had neck pain for at least 3 months and it is moderate to severe, but you haven't been in a recent neck pain rehab or exercise program.
Ankara, AltindagAges 20–65 - NCT07432841Recruiting
Personalized brain stimulation for chronic pain
This trial tests a personalized form of brain stimulation (high-definition tDCS) to treat chronic pain that has not improved with other treatments. If you have had pain for at least 6 months and it is still moderate to severe, this may be an option to explore.
MilanAges 18–75 - NCT07433634Recruiting
Tracking recovery after BVN ablation for chronic low back pain
This study looks at how well a procedure called BVN ablation (which uses heat to stop pain signals from the vertebrae) works for people with chronic low back pain that comes from the spine. If you already have this procedure scheduled, researchers will track your recovery and pain relief over time.
Guilford, ConnecticutAges 18 years+ - NCT07434583Recruiting
Force sensor study for laryngeal surgery patients
This trial tests a force sensor tool used during laryngeal surgery (surgery on the voice box) via direct laryngoscopy (a tube inserted through the mouth). It may help surgeons apply the right amount of force to reduce tongue injuries.
San Francisco, CaliforniaAges 18 years+ - NCT07435168Recruiting
Chest pain and hidden cardiac amyloidosis study
This study looks for signs of a condition called cardiac amyloidosis in people who have chest pain but no blocked heart arteries. It aims to find hidden cases that might be missed with standard tests.
CopenhagenAges 65 years+ - NCT07435909Recruiting
Bupivacaine for pain after laparoscopic hysterectomy
This trial tests if injecting a numbing medicine called bupivacaine into the abdomen during surgery can reduce pain after a laparoscopic hysterectomy (uterus removal through small cuts). It may help you recover with less discomfort.
Istanbul, GaziosmanpaşaAges 35–75 - NCT07436806Recruiting
Comparing nerve blocks for pain after chest surgery
This trial compares two types of nerve blocks to see which one better prevents long-term pain after video-assisted chest surgery. It may help find a way to reduce chronic pain after your procedure.
Istanbul, BagcilarAges 18–75 - NCT07437469Recruiting
Binaural beats for pain and anxiety after surgery
This trial tests if listening to binaural beats (a type of sound therapy) after hip or knee replacement surgery can help reduce pain and anxiety. You would receive the sound therapy through headphones while in the recovery room.
Miami, FloridaAges 18–99 - NCT07440069RecruitingPhase 4
Pain relief options for women during active labor
This trial compares the pain relief and effects of tramadol, paracetamol (also known as acetaminophen), and a placebo in women during active labor. It aims to find which option works best and is safest for mothers and babies.
Tegucigalpa, Francisco Morazán DepartmentAges 15–45 - NCT07440576Recruiting
Numbing shot for pain after prolapse surgery
This trial tests if a numbing injection in the cervix area can reduce pain after minimally invasive prolapse surgery. If you're having this surgery, the study may help determine if the shot makes recovery more comfortable.
Istanbul, IstanbulAges 18 years+ - NCT07440836Recruiting
Exercises for separated belly muscle after childbirth
This study compares two types of exercises to help close the gap in your belly muscles that can happen after pregnancy. It may be for you if you have a gap larger than 4cm and certain types of pain.
Lahore, Punjab ProvinceAges 25–40
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,764 recruiting pain medicine studies from the U.S. registry right now, out of 6,842 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.