Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,764 recruiting studies in this area right now.
By phase
- Not applicable3,111
- Phase 4251
- Phase 2144
- Phase 3104
- Phase 197
- Phase 2/Phase 335
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University97
- Cairo University62
- Beijing Tiantan Hospital34
- Ain Shams University32
- Tanta University30
- Foundation University Islamabad26
- Mayo Clinic26
- Stanford University24
- VA Office of Research and Development22
- Hacettepe University20
Where studies are running
- California158
- New York80
- Massachusetts68
- Florida65
- Texas52
- Ohio48
- Maryland42
- Minnesota41
- Illinois38
- North Carolina38
Recruiting studies3,763 total
- NCT07440862Recruiting
Pelvic floor exercises and belt for pubic pain in pregnancy
This trial tests if pelvic floor exercises and a support belt work better than either alone for symphysis pubis dysfunction, a condition that causes pain in the front of the pelvis during pregnancy.
Daska KalanAges 25–40 - NCT07440940Recruiting
Timing of pain blocks for gallbladder surgery recovery
This study is testing whether giving a numbing block (under the ribs and around the belly button) at a certain time before gallbladder removal surgery helps reduce pain after the operation. It aims to find the best timing for these pain blocks to improve your recovery.
SeoulAges 18–80 - NCT07442435Recruiting
Reiki for recovery after knee replacement surgery
This study tests whether adding Reiki (a gentle hands-on relaxation therapy) to standard care helps people feel better and recover more comfortably after a first-time knee replacement. It may be a good fit if you are having your first knee replacement, are not on certain medications, and haven't tried energy therapies before.
SinopAges 18 years+ - NCT07442721Recruiting
Comparing two types of nerve blocks for hip replacement pain
This study compares two different nerve block methods to see which provides better pain relief for people having a partial hip replacement. It will help doctors choose the best way to manage pain after surgery.
El Fayoum Qesm, Faiyum GovernorateAges 50–90 - NCT07444112Recruiting
Myofascial release for text neck in university students
This trial tests if a hands-on therapy called myofascial release can help university students with text neck (neck pain from looking down at phones). It aims to reduce pain and improve neck function.
Lahore, Punjab ProvinceAges 18–30 - NCT07444125Recruiting
Leg rotation treatment for sciatica
This trial tests a two-leg rotation technique to relieve sciatica caused by lumbar disc problems. It may help if you have pain that travels from your lower back down past your knee.
Ha'il, Ha'il RegionAges 18–50 - NCT07444697Recruiting
Erections after heart stent in men with and without heart attack
This study looks at how having a stent placed affects men's ability to have erections. It compares men who had a heart attack with those who had stable chest pain. If you take part, you will fill out short questionnaires about your sexual function and recovery for 6 months.
KirikkaleAges 30–75 - NCT07444957Recruiting
Safety of a drug-coated balloon for heart artery blockages
This study tests a special balloon coated with a drug called sirolimus to open blocked heart arteries. It may be an option for people with coronary artery disease who need a less invasive treatment.
Vigo, PontevedraAges 18 years+ - NCT07445386Recruiting
Nerve block for upper abdominal cancer pain
This trial compares two types of nerve blocks to treat severe pain from upper abdominal cancers like stomach, pancreas, or liver cancer. It may be an option if your pain hasn't been controlled with standard treatments.
AnkaraAges 18 years+ - NCT07446868Recruiting
Comparing two nerve blocks for pain after mastectomy
This trial compares two nerve-block techniques (SPSIP and ESPB) to see which one provides better pain relief after breast cancer surgery. The goal is to reduce pain and improve recovery after a modified radical mastectomy.
Cairo, Cairo GovernorateAges 18–65 - NCT07447323Recruiting
Thumb joint position sense study for thumb base arthritis
This study tests how well people with thumb base arthritis can sense their thumb's position. It aims to understand how this sense is affected by the condition and may help improve future treatments.
Ankara, AnkaraAges 25–75 - NCT07447609Recruiting
Reiki for breastfeeding, pain and comfort after C-section
This study tests whether Reiki, a gentle energy therapy, can help with breastfeeding, reduce pain, and improve comfort after a C-section. If you qualify, you would receive Reiki sessions and be monitored for its effects.
SamsunAges 18–45 - NCT07447687RecruitingPhase 1/Phase 2
Soy tomato juice for pancreatitis symptoms
This trial tests whether drinking a special soy tomato juice can help people with chronic or recurrent pancreatitis feel better and have fewer flare-ups.
Columbus, OhioAges 18–80 - NCT07447830Recruiting
Virtual reality for pain relief during wound care
This study tests if using a virtual reality headset during wound care can reduce pain for people with pressure ulcers in long-term care. It aims to find a more comfortable way to manage wound treatment.
Montreal, QuebecAges Any age - NCT07447856RecruitingPhase 1
Herbal plasters for pain relief while using opioids
This trial tests a topical herbal plaster to see if it can help reduce pain in people with cancer who are already taking opioids. The plaster is placed on the most painful area and may allow you to use less opioid medication.
Basking Ridge, New JerseyAges 18 years+ - NCT07448285RecruitingPhase 3
Platelet-rich plasma injection for chronic shoulder pain
This trial tests whether injecting platelet-rich plasma (a concentration of your own blood cells that may help healing) can reduce chronic shoulder pain. It's for people whose pain hasn't improved with standard painkillers and who have a specific shoulder tendon condition.
Barakaldo, BizkaiaAges 35–75 - NCT07448246Recruiting
Rhomboid block for pain after breast implant surgery
This trial tests if a specific nerve block (rhomboid intercostal block) can reduce pain after breast implant surgery. If you are having bilateral breast implants and are in good general health, you may be eligible.
Aydin, EfelerAges 18–65 - NCT07452120Recruiting
Comparing two nerve blocks for pain after hip surgery
This trial studies two different nerve block methods to see which provides better pain relief after hip replacement surgery. If you are having hip surgery and want to help find the best way to manage pain, this study may be for you.
Sivas, SivasAges 18 years+ - NCT07452614Recruiting
Predicting pulp treatment success with metabolic markers
This trial tests if a metabolic biomarker can predict how well a vital pulp treatment works for tooth pain caused by deep cavities. It aims to help patients keep their natural teeth instead of needing root canals.
BaghdadAges 16–50 - NCT07452627Recruiting
Comparing Nerve Blocks for Sternotomy Pain
This study compares three different injection techniques (nerve blocks) to reduce pain after heart surgery that cuts through the breastbone. The goal is to find the best way to control pain with fewer side effects.
Bursa, NilüferAges 18–80 - NCT07452770Recruiting
Stress ball use during cataract surgery for pain and fear
This study tests whether squeezing a stress ball during cataract surgery can help reduce pain, fear, and increase satisfaction. It is for people having their first cataract surgery who are awake and able to squeeze a ball.
Istanbul, IstanbulAges 18 years+ - NCT07453485Recruiting
Electrical stimulation for Achilles tendon pain and function
This study tests if a brief session of neuromuscular electrical stimulation can reduce pain and improve function in people with Achilles tendon problems, such as midportion or insertional pain, or a healed rupture that happened at least 3 months ago.
Brasília, Federal DistrictAges 18–60 - NCT07453524Recruiting
Understanding what matters to people with chronic pain
This study asks people with chronic pain about their preferences and experiences. Your answers will help doctors understand what matters most to patients like you.
BrusselsAges 18 years+ - NCT07453576Recruiting
Comparing bleach strengths for root canal retreatment pain
This trial tests if different concentrations of sodium hypochlorite (a disinfectant used in root canals) affect pain and certain natural chemicals in the tooth during root canal retreatment. It may help find the best option to reduce discomfort.
Erzurum, ErzurumAges 18–65
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,764 recruiting pain medicine studies from the U.S. registry right now, out of 6,842 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.