Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,764 recruiting studies in this area right now.
By phase
- Not applicable3,111
- Phase 4251
- Phase 2144
- Phase 3104
- Phase 197
- Phase 2/Phase 335
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University97
- Cairo University62
- Beijing Tiantan Hospital34
- Ain Shams University32
- Tanta University30
- Foundation University Islamabad26
- Mayo Clinic26
- Stanford University24
- VA Office of Research and Development22
- Hacettepe University20
Where studies are running
- California158
- New York80
- Massachusetts68
- Florida65
- Texas52
- Ohio48
- Maryland42
- Minnesota41
- Illinois38
- North Carolina38
Recruiting studies3,763 total
- NCT07553000Recruiting
Splinting for Wrist Fractures Study
This study tests how splinting helps people with suspected broken wrists (fractures of the radius bone at the wrist). You'll be included if you have moderate to severe wrist pain and imaging shows a fracture.
MalmöAges 18 years+ - NCT07554664Recruiting
Desk Work, Stress, and Muscle Pain With or Without Migraine
This study looks at how office work, job stress, and muscle tension relate to migraines and neck/shoulder pain in desk workers. Researchers want to understand if certain body changes (called central sensitization) connect these issues, which could lead to better ways to help office workers feel better.
Gaziantep, MerkezAges 18–65 - NCT07555314Recruiting
Outpatient Catheter for Lidocaine Pain Treatment
This trial tests using a special catheter (thin tube) to deliver lidocaine—a numbing medication—to treat chronic pain on an outpatient basis. Researchers want to see if this approach helps manage long-term pain effectively.
WarsawAges 18 years+ - NCT07555795Recruiting
Game-Based Wearable Sensors to Help Core Muscles and Back Pain
This study tests a wearable belt with sensors and haptic feedback (gentle vibrations) combined with interactive gaming to help strengthen your core muscles and reduce lower back pain. The goal is to make exercise more engaging and effective for chronic back pain.
LondonAges 18 years+ - NCT07556536Recruiting
Nerve block comparison for kidney removal surgery pain
This trial tests two different types of numbing injections (nerve blocks) to see which one works better at controlling pain after open kidney removal surgery. You would receive one of these blocks during surgery to help reduce pain and the amount of strong pain medication you need afterward.
Al FayyumAges 18–65 - NCT07556952RecruitingPhase 4
Dexamethasone to reduce pain after breast removal surgery
This study tests whether dexamethasone (a common anti-inflammatory medication) can reduce pain after mastectomy (surgical removal of breast tissue). Researchers want to see if it helps patients recover with less pain and potentially fewer pain medications.
Montreal, QuebecAges 18–75 - NCT07557108Recruiting
Nerve Blocks to Improve Recovery After Heart Surgery
This study tests whether special numbing injections around nerves in the chest wall (fascial plane blocks) help patients recover better and have less pain after open-heart surgery. The goal is to see if this technique improves how you feel and function in the days after your operation.
Ordu, AltinorduAges 18–70 - NCT07557875Recruiting
Laser Treatment for Tongue-Tie in Young Children
This study tests whether a special laser can safely and effectively treat tongue-tie (a condition where the tissue under the tongue is too tight) in children ages 3–6. The goal is to see if the laser helps the tongue move better and heals faster than other methods.
Ho Chi Minh CityAges 3–6 - NCT07560267Recruiting
Ultrasound nerve block for kidney surgery pain relief
This trial tests whether a special nerve-numbing injection in the back (guided by ultrasound imaging) can reduce pain after kidney removal surgery. If it works well, it could help patients recover more comfortably with less need for strong pain medications.
DhakaAges 18–64 - NCT07561333Recruiting
Pain Relief Methods for Knee Replacement Surgery
This study compares two different nerve-blocking anesthesia techniques to see which one controls pain better after knee replacement surgery. Both methods are designed to numb the area around your knee so you need less pain medication afterward.
Çorum, CentreAges 18–80 - NCT07561411Recruiting
Nerve blocks to reduce pain after breast removal surgery
This trial tests two types of nerve-blocking injections given during breast removal surgery to see which one better prevents long-term pain afterward. Both are given alongside general anesthesia and may help you recover with less chronic pain.
BeirutAges 18–80 - NCT07562048Recruiting
Comfort Cuddling for Children in Critical Care
This study looks at whether gentle cuddling and physical comfort help children feel better while they're in the intensive care unit. Researchers believe close contact with caregivers may reduce stress and improve how children recover.
Calgary, AlbertaAges Up to 18 years - NCT07564778Recruiting
Pain Management After Cardiac Arrest Recovery
This study examines how to better treat pain in patients who have survived cardiac arrest and are unconscious in the hospital. Researchers want to understand pain experiences and test pain-relief strategies during early recovery.
HalmstadAges 18 years+ - NCT07565844Recruiting
Injected treatments for nerve pain after shingles
This trial tests three injected treatments—tiny cell particles, platelet-rich plasma, and steroids—directly into the skin to reduce long-lasting nerve pain that follows shingles. If you've had persistent shingles pain for at least 3 months, this study may help ease your discomfort.
Zagazig, ZagazigAges 18 years+ - NCT07566806Recruiting
Cord Plasma Eye Drops for Nerve Pain in the Eye
This trial tests whether special eye drops made from cord plasma (a blood product) can reduce chronic eye pain caused by damaged nerves in the cornea (the clear front part of your eye). You may qualify if you have had eye pain for at least 3 months without obvious surface damage.
Singapore, SingaporeAges 21 years+ - NCT07567300Recruiting
Understanding Pain Patterns in Migraine and Neck or Back Pain
This study explores how migraine headaches, neck pain, and lower back pain may share similar pain mechanisms in the body. Researchers will ask you questions to understand your pain patterns and help identify connections between these conditions.
Gaziantep, MerkezAges 18–65 - NCT07568093Recruiting
Music therapy to reduce agitation after abdominal surgery
This study tests whether listening to music after abdominal surgery can help reduce agitation and anxiety during recovery. Researchers will compare patients who receive music therapy with standard care to see if it improves comfort and outcomes.
Hanover, Lower SaxonyAges 18 years+ - NCT07568418Recruiting
Skin Response Monitoring in Ventilated Premature Babies
This study measures how a premature baby's skin responds to stress while on a breathing machine. Researchers want to understand if skin conductance (electrical activity of the skin) is a good way to detect pain and discomfort in ventilated babies.
Uppsala, UpplandAges 5 months+ - NCT07569731Recruiting
Understanding Fibrous Dysplasia Through Patient Data and Tissue
This study collects information from patients with fibrous dysplasia (a bone condition where normal bone is replaced by fibrous tissue) and related syndromes to better understand the disease. Researchers will review your medical records, imaging scans, and stored tissue samples to learn more about how the disease develops and progresses.
Bologna, BOAges Any age - NCT07571837Recruiting
Nano-medication to reduce inflammation after root canal retreat
This study tests a special nano-sized (extremely tiny) medication placed inside a tooth after a previous root canal treatment failed. The goal is to reduce inflammation and swelling in the bone around the tooth's tip so it can heal better.
Cairo, Nasr CityAges 20–40 - NCT07574307Recruiting
Kinesio Tape for Meniscus Knee Injuries
This study tests whether special therapeutic tape (kinesiotape) can help reduce pain and improve function in people with meniscus injuries in the knee. The meniscus is a piece of cartilage that cushions your knee, and this trial sees if the tape can help your body heal without surgery.
BalıkesirAges 18–50 - NCT07575139Recruiting
Massage and cupping therapy for teen neck pain
This study tests whether myofascial release (deep muscle massage) and dynamic cupping can help teenagers with moderate to severe neck pain and poor posture. The goal is to see if these hands-on therapies can reduce pain and improve how you hold your body.
LahoreAges 7–12 - NCT07576101Recruiting
Blood Flow Restriction Training for Lower Back Pain
This study tests whether a special exercise technique that carefully reduces blood flow to your legs while exercising can help reduce chronic lower back pain. The goal is to see if this method combined with training can strengthen your muscles and relieve pain more effectively.
IslamabadAges 18–45 - NCT07576127Recruiting
Gongs Mobilization and Stretching for Frozen Shoulder
This study tests two hands-on treatment techniques—gongs mobilization and proprioceptive neuromuscular facilitation (a type of guided stretching)—to help reduce stiffness and improve movement in frozen shoulder. Frozen shoulder causes pain and loss of motion in the shoulder joint; this trial aims to see if these treatments can help restore function.
Rawalpindi, Punjab ProvinceAges 40–60
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,764 recruiting pain medicine studies from the U.S. registry right now, out of 6,842 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.