Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,576 recruiting studies in this area right now.
By phase
- Not applicable2,951
- Phase 4240
- Phase 2131
- Phase 3102
- Phase 193
- Phase 2/Phase 337
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University84
- Cairo University60
- Beijing Tiantan Hospital34
- Tanta University33
- Ain Shams University28
- Foundation University Islamabad28
- Mayo Clinic25
- VA Office of Research and Development23
- Hacettepe University22
- Stanford University21
Where studies are running
- California152
- New York79
- Massachusetts65
- Florida64
- Texas50
- North Carolina41
- Illinois40
- Maryland39
- Ohio39
- Minnesota37
Recruiting studies3,576 total
- NCT06654635Recruiting
Ultrasound-guided nerve blocks for upper abdominal surgery
This trial compares two types of nerve blocks to control pain after upper abdominal surgery. One block targets the rhomboid intercostal area, and the other targets the erector spinae muscle. This could help reduce pain and improve recovery.
Tanta, El-GharbiaAges 21–65 - NCT06175884Recruiting
Communication skills for chronic muscle and joint pain
This trial tests how a physical therapist's communication style affects pain and function in people with long-term muscle or joint pain. Participants will fill out questionnaires and watch a video to see if better communication improves outcomes.
LamiaAges 18–65 - NCT06655571Recruiting
Comparing two ways to give a caudal block to children
This trial compares two techniques for giving a caudal block (a numbing injection near the tailbone) to children having surgery. One method uses the usual way, and the other uses ultrasound imaging to guide the needle.
Tunis, Tunis GovernorateAges 6 months–6 years - NCT06655506Recruiting
Enhanced Recovery for Gynecologic Cancer Surgery
This trial studies whether an enhanced recovery after surgery (ERAS) program improves outcomes for people with gynecologic cancer. It aims to help you recover faster and with fewer complications.
Athens, AthensAges 25–85 - NCT06426875Recruiting
Isometric training for shoulder pain in bowlers
This trial tests if isometric muscle training (holding still muscle contractions) can reduce shoulder pain and improve function and bowling performance in male bowlers. It may help if your pain affects your game and causes emotional distress.
Rawalpindi, Punjab ProvinceAges 18–30 - NCT06656182Recruiting
Mobilization techniques for scapulocostal syndrome
This trial tests two types of gentle joint movements (SNAGs and scapular mobilizations) to see if they reduce pain and improve shoulder and neck movement in people with scapulocostal syndrome. If you have chronic neck pain and trouble lifting your arm overhead, this study may help.
Rawalpindi, Punjab ProvinceAges 18–40 - NCT06656156Recruiting
Stretching technique for chronic low back pain relief
This trial tests a physical therapy stretching method called PNF on the hip and hamstring muscles to see if it reduces chronic low back pain. It may help if you have had non-specific low back pain for over 3 months with tightness in your hips or legs.
Karachi, SindhAges 15–40 - NCT06651775Recruiting
High-Intensity Laser Therapy for Chronic Leg Pain from Herniated Disc
This study tests whether a type of high-intensity laser therapy (HILT) can help relieve leg pain caused by a herniated disc in the lower back. It is for people who have not had recent back treatments or surgery.
Ankara, CankayaAges 18–65 - NCT06658210Recruiting
Soft tissue massage and pelvic exercises for pelvic scar tissue
This study tests whether gentle massage and pelvic floor exercises can help relieve pain and discomfort from pelvic scar tissue (adhesions) in women who have had a hysterectomy. It may be an option for you if you are married, between 40 and 60, and healthy enough for these treatments.
Lahore, Punjab ProvinceAges 40–60 - NCT06658327Recruiting
Stretching for knee arthritis in postmenopausal women
This study compares two types of stretching to see which better reduces pain and improves movement in postmenopausal women with knee osteoarthritis. It may help you find a simple, drug-free way to manage your symptoms.
Lahore, Punjab ProvinceAges 50–65 - NCT07682519Recruiting
Home vs. in-person rehab for hemophilia pain
This study compares a rehabilitation program you can do at home using video calls (telerehabilitation) with in-person rehabilitation sessions. The goal is to see if the home-based option works as well as office visits for reducing chronic joint pain in adults with hemophilia.
Santiago, Santiago MetropolitanAges 18–60 - NCT07688044Recruiting
How food and bacteria cause belly pain in IBS
This study looks at how certain foods and gut bacteria might trigger abdominal pain in people with Irritable Bowel Syndrome (IBS). If you have IBS and frequent belly pain, you may help researchers understand the link between diet, bacteria, and pain.
Kingston, OntarioAges 18–70 - NCT07685418Recruiting
Pressure therapy and home exercises for neck pain
This trial tests whether a hands-on technique called ischemic compression (applying gentle pressure to trigger points) plus home exercises helps relieve long-term neck pain that has no specific medical cause.
Istanbul, BakırköyAges 17–65 - NCT07681336Recruiting
Ear nerve stimulation for chronic low back pain
This trial tests if stimulating the vagus nerve through the ear can reduce chronic low back pain in people who haven't gotten enough relief from painkillers. It aims to see if this non-invasive treatment can help manage pain without medication.
Ghent, Oost-VlaanderenAges 30–60 - NCT07682051Enrolling by invitation
Resistance training for patellar tendon pain
This study tests whether resistance training can improve the health of the patellar tendon in people with patellar tendinopathy (pain at the knee cap). It may help you recover strength and reduce pain over time.
Graz, StyriaAges 18–50 - NCT07681687Recruiting
Neck muscle control therapy for long-term neck pain
This study tests two different physical therapy techniques—one focusing on how your brain controls neck movement, and another that releases muscle tension—to see which works better for long-term neck pain. If you have chronic neck pain and limited movement, you may be able to join.
IslamabadAges 18–35 - NCT07680998Recruiting
Pain monitor device for recovery after day surgery
This trial tests a device that monitors pain and recovery after outpatient surgery. It may help manage pain more safely and improve your comfort after you go home.
Nîmes, GardAges 18 years+ - NCT07687290Recruiting
Comparing two nerve blocks for hip fracture pain before spinal anesthesia
This trial tests two types of nerve blocks to see which one works better for managing pain while positioning hip fracture patients before they receive spinal anesthesia. The goal is to find a more comfortable way to prepare for surgery.
CairoAges 18–70 - NCT07683468Recruiting
A self-help kit for pain during sex with endometriosis
This trial tests if a special kit you can use at home helps reduce sexual pain caused by endometriosis. It might offer a new way to manage this common symptom.
StainsAges 18–45 - NCT07685340Recruiting
Cupping vs Massage Tool for Chronic Low Back Pain
This trial tests two hands-on therapies—dry cupping and a special massage technique—to see which works better for long-term low back pain caused by muscle knots. You may be able to join if your pain has lasted over 3 months and you have trigger points.
Rawalpindi, Punjab ProvinceAges 25–45 - NCT07683273Enrolling by invitation
Breathing exercises for neck and upper back pain
This study tests whether diaphragmatic breathing exercises can help reduce chronic, non-specific neck and upper back pain. If you have this type of pain that is not caused by an injury or disease, you may be able to join.
Trabzon, OrtahisarAges 18–60 - NCT07681648Enrolling by invitationPhase 4
Nerve blocks vs local numbing for lumbar spine surgery
This study compares two types of nerve blocks (a longissimus plane block and a multifidus plane block) to a local numbing injection for pain control during lumbar spine surgery. It aims to find which method works best for patients having back surgery.
Aswān, Aswan GovernorateAges 18–65 - NCT07687069Recruiting
Numbing injection versus IV pain medicine for breast reduction
This study compares two ways to manage pain after breast reduction surgery: one uses a numbing injection near the chest muscles (called an ESPB block), and the other uses numbing medicine given through an IV. If you're having breast reduction, this might help find a better way to control your pain with fewer side effects.
WarsawAges 18–75 - NCT07681661Recruiting
Massage Gun vs Deep Massage for Shoulder Knots
This study compares using a handheld massage device (like a massage gun) with deep pressure massage to treat painful knots in the upper shoulder muscle. It may help people with moderate to severe neck or shoulder pain who have not had recent treatment.
IslamabadAges 24–45
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,576 recruiting pain medicine studies from the U.S. registry right now, out of 6,474 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.