Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,576 recruiting studies in this area right now.
By phase
- Not applicable2,951
- Phase 4240
- Phase 2131
- Phase 3102
- Phase 193
- Phase 2/Phase 337
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University84
- Cairo University60
- Beijing Tiantan Hospital34
- Tanta University33
- Ain Shams University28
- Foundation University Islamabad28
- Mayo Clinic25
- VA Office of Research and Development23
- Hacettepe University22
- Stanford University21
Where studies are running
- California152
- New York79
- Massachusetts65
- Florida64
- Texas50
- North Carolina41
- Illinois40
- Maryland39
- Ohio39
- Minnesota37
Recruiting studies3,576 total
- NCT06652724Recruiting
Psychological help for chronic pain in fibromyalgia and migraine
This study looks at how psychological factors and treatments might help with chronic pain in people with fibromyalgia and/or chronic migraine. It compares different groups to understand what works best.
Rome, RMAges 18–50 - NCT07689461Recruiting
Virtual reality for pain after hip replacement
This trial tests if using virtual reality can help reduce pain after hip replacement surgery. It may be a good option if you are having a hip replacement and have moderate to severe pain.
MalatyaAges 18–99 - NCT07689214Recruiting
Normast for diabetic nerve pain in adults
This study tests an oral medication called Normast to see if it helps adults with diabetic polyneuropathy, a type of nerve damage from diabetes. The trial aims to find out if the drug can reduce symptoms and improve quality of life.
Rome, ItalyAges 18–80 - NCT07693998Enrolling by invitation
Pain education class for fibromyalgia or chronic back pain
This trial tests a class to help people with fibromyalgia or chronic low back pain learn about their pain and how to manage it. It might help you feel better and understand your pain.
Valencia, ValenciaAges 18 years+ - NCT07691840Recruiting
Intrathecal therapy vs. standard care for severe cancer pain
This trial compares a treatment that delivers pain medicine directly to the spinal cord (intrathecal therapy) with usual pain control. It is for people with severe cancer pain that is not helped by oral or intravenous opioids.
JetteAges 18 years+ - NCT07688889Enrolling by invitation
Anthropometric effects on shoulder block success
This trial looks at how body measurements affect the success and timing of a nerve block for shoulder surgery. It aims to improve pain relief during the procedure.
AmasyaAges 18 years+ - NCT07696650Recruiting
Choose to Move Replacement Ready study
This study looks at a program called Choose to Move Replacement Ready (CTM-RR) for older adults and the people who help them get active. It tests how well the program works for activity coaches, participants, and healthcare referral partners.
Vancouver, British ColumbiaAges 50 years+ - NCT07690449Recruiting
CT signs of nerve irritation in sciatica
This study looks at three specific signs on a CT scan that may show nerve-root irritation in people with sciatica. It only includes patients who are already scheduled for a CT-guided nerve injection to treat their pain.
Nice, Alpes MaritimesAges 18 years+ - NCT07693270Recruiting
Study looking for markers of pain and opioid response after injury or surgery
This study is looking for biological markers (like blood tests) that can predict how people will respond to pain and opioids after a traumatic injury or surgery. The goal is to help doctors tailor pain treatment to each person.
La Jolla, CaliforniaAges 18 years+ - NCT07689045Recruiting
Comparing two nerve blocks for shoulder surgery pain
This trial compares two types of nerve blocks for pain control during and after Bankart or Latarjet shoulder surgery. The goal is to see which block provides better pain relief and preserves arm strength.
Cairo, Cairo GovernorateAges 18–65 - NCT07697222Recruiting
Pain block comparison for pectus excavatum repair
This trial compares two types of nerve blocks to control pain after a minimally invasive surgery to fix a sunken chest. It aims to see which block works better for recovery.
Istanbul, IstanbulAges 15–25 - NCT07695168Recruiting
Digital course and rehab for knee osteoarthritis
This study tests whether a digital program with special sensors and a digital twin can help reduce knee pain and improve mobility in older adults with knee osteoarthritis. It also includes healthy adults for comparison.
TaipeiAges 20–80 - NCT07694063Recruiting
Online yoga for frequent migraines
This trial tests if online Hatha yoga classes can help adults who have frequent migraines (but not daily). If you have migraines 8–14 days a month and are already on stable medication, this study may offer a gentle addition to your treatment.
Seville, SevillaAges 18–65 - NCT07692126Recruiting
Neck pain and hand strength: core vs shoulder exercises
This study compares two types of exercises to see which better improves hand grip strength and neck pain. If you have had chronic myofascial neck pain (trigger points) in the upper shoulder muscle for over 6 months, this trial may help find which exercise works best for you.
Giza, Giza GovernorateAges 25–45 - NCT07688902Recruiting
Comparing two injection methods for partial rotator cuff tears
This study compares two ways of injecting a sugar-water solution (5% dextrose) into the shoulder to treat partial rotator cuff tears. It may help reduce pain and improve shoulder function without surgery.
AnkaraAges 18–75 - NCT07689162RecruitingPhase 2
Long-acting vs standard numbing for nose surgery pain
This study compares two types of numbing medicine used during open rhinoplasty (nose surgery) to see which one controls pain better after surgery. One is a long-acting version (liposomal bupivacaine) and the other is the standard numbing medicine (bupivacaine).
St Louis, MissouriAges 18 years+ - NCT07694882Recruiting
Gentle pressure techniques for chronic neck pain
This study tests two different types of gentle pressure techniques (myofascial release) to see which one helps relieve long-term neck pain and improve everyday function. It is for people with chronic neck pain that isn't caused by a specific injury or disease.
Famagusta, HatayAges 18–45 - NCT07696741Recruiting
Pain Reprocessing Therapy for Chronic Lower Back Pain
This study tests a type of talk therapy called pain reprocessing therapy (PRT) for adults with chronic lower back pain. The goal is to see if PRT can help reduce pain and improve quality of life.
Toronto, OntarioAges 18–65 - NCT07696260Recruiting
Emotions and tailbone pain study
This study looks at how people with chronic tailbone pain (coccydynia) understand and express their emotions—a trait called alexithymia. The goal is to see if there is a link between emotional awareness and the severity of tailbone pain.
IstanbulAges 18 years+ - NCT07695935Recruiting
Pain relief after hernia repair: nerve block vs low-dose morphine
This study compares two ways to manage pain after open inguinal hernia repair: a nerve block (injection near the abdominal muscles) versus a low-dose painkiller (morphine) given through the spinal needle. The goal is to find which method provides better relief with fewer side effects.
ÇorumAges 18–80 - NCT07693621Recruiting
Pain relief medicine added to numbing drug for gallbladder surgery
This trial tests if adding dexmedetomidine or magnesium to a standard numbing medication (bupivacaine) injected into the belly during gallbladder surgery can improve pain control and recovery. It aims to find a better way to manage pain after surgery.
AlexandriaAges 18–60 - NCT07696286Recruiting
Alexithymia in chronic pain patients with a spinal cord stimulator
This study looks at a condition called alexithymia (difficulty identifying and describing emotions) in people who have chronic pain and a spinal cord stimulator. It aims to help doctors better understand how emotions affect pain treatment.
IstanbulAges 18 years+ - NCT07696923Recruiting
Treating frozen shoulder with microembolization or steroid injection
This trial compares two treatments for frozen shoulder: a new procedure that blocks tiny blood vessels (TAME) and a steroid injection. You must have had shoulder pain for at least a month and be willing to do physical therapy.
TaipeiAges 18–80 - NCT07694141Recruiting
Pain Relief After Chest Surgery
This trial studies how well different pain medications work after thoracic (chest) surgery. It aims to find the best way to manage pain and improve recovery.
Las Palmas de Gran Canaria, Las PalmasAges 18 years+
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,576 recruiting pain medicine studies from the U.S. registry right now, out of 6,474 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.