Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,749 recruiting studies in this area right now.
By phase
- Not applicable3,095
- Phase 4251
- Phase 2145
- Phase 3104
- Phase 197
- Phase 2/Phase 335
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University96
- Cairo University62
- Beijing Tiantan Hospital34
- Ain Shams University31
- Mayo Clinic28
- Tanta University28
- Foundation University Islamabad26
- Stanford University24
- VA Office of Research and Development22
- Hacettepe University20
Where studies are running
- California160
- New York81
- Massachusetts68
- Florida63
- Texas51
- Ohio47
- Maryland42
- Minnesota42
- North Carolina38
- Illinois37
Recruiting studies3,748 total
- NCT07608861Recruiting
Numbing Block to Reduce Pain Medicine During Nose Surgery
This study tests whether a special numbing injection in the upper jaw (bilateral maxillary block) helps reduce the amount of pain medication needed during septorhinoplasty—a surgery to reshape the nose and straighten the septum. The goal is to find ways to use less strong pain medication during surgery.
Yenimahalle, AnkaraAges 18–65 - NCT06667739Recruiting
Promoting physical activity after leg amputation
This study tests a program to help people who have lost a leg due to diabetes or blood vessel disease become more active. It uses coaching and online modules to support your progress.
Toronto, OntarioAges 18 years+ - NCT07633340Recruiting
Shock Wave Therapy Plus Rehab for Shoulder Blade Problems
This study compares two treatment approaches for scapular dyskinesis (abnormal shoulder blade movement): one group receives shock wave therapy along with standard exercises, while the other group does exercises alone. Researchers want to see if adding shock wave therapy helps improve shoulder blade function and reduces pain.
TantaAges 18 years+ - NCT07515885Recruiting
Electroacupuncture for Shingles Pain Relief
This study tests whether electroacupuncture (a form of acupuncture with mild electrical stimulation) can reduce pain from shingles (herpes zoster), a viral infection that causes painful skin rashes. Researchers will also measure certain markers in your blood to understand how the treatment works.
Hangzhou, ZhejiangAges 20–80 - NCT07625007Recruiting
Shortwave Therapy for Diabetic Nerve Pain
This trial tests a shortwave treatment to relieve pain and other nerve symptoms in people with diabetic peripheral neuropathy (nerve damage from diabetes). It is for adults who have not found enough relief from standard nerve medications.
ChongqingAges 18–85 - NCT06620471Recruiting
Better nerve blocks with impedance testing
This study looks at whether adding impedance testing to ultrasound guidance improves accuracy for arm and leg nerve blocks. If you need a nerve block for surgery, this may help us learn how to make them safer and more effective.
Beirut, BeirutAges 18–90 - NCT07061769Enrolling by invitation
Using a gentle head device to help with nerve pain from chemo
This trial tests a low-intensity cranial PEMF device to see if it can reduce nerve pain caused by chemotherapy. Participants use the device at home and receive text messages to track their symptoms.
Newport Beach, CaliforniaAges 18–60 - NCT06863649Recruiting
Games for shoulder and arm pain after a stroke
This trial tests if doing fun, non-immersive video game–like exercises for a short time can help reduce chronic pain in the shoulder or arm after a stroke. It looks at whether these exercises can improve arm movement and make daily activities feel easier.
Exeter, DevonAges 18 years+ - NCT07520487Recruiting
Ketamine Plus Spinal Anesthesia for Older Adults Undergoing Leg Surgery
This study tests whether adding ketamine (a type of anesthetic medication) to spinal anesthesia—numbing medication injected near the spine—can make the numbness last longer for older adults having leg surgery. The goal is to see if this combination improves pain control after surgery.
Cairo, Giza GovernorateAges 65 years+ - NCT06766994Recruiting
Pain relief methods after hysterectomy: a recovery comparison
This study compares two different ways to manage pain after abdominal hysterectomy surgery. The goal is to see which method helps you recover better and feel more comfortable.
Erzurum, YakutiyeAges 18–65 - NCT07379866Recruiting
Nerve blocks for pain relief after tonsil removal in children
This trial tests if injecting numbing medicine near certain nerves in the head and neck can reduce pain after tonsil and adenoid surgery in children aged 5–13. It may help them recover more comfortably.
Cairo, GovernorateAges 5–13 - NCT07525453Recruiting
Exercise Programs to Improve Balance in Older Adults
This study tests three different exercise programs designed to help older adults improve their balance and reduce fall risk. You'll participate in one of the programs and have your balance tested before and after to see which approach works best.
Istanbul, AtaşehirAges 65 years+ - NCT07526038Recruiting
Physical therapy for postpartum pelvic joint pain
This study tests whether a hands-on movement technique combined with core exercises helps postpartum mothers with sacroiliac joint pain (a pain in the lower back/buttock area). The research compares this combined approach to see if it reduces pain and improves function.
Islamabad, Punjab ProvinceAges 20–40 - NCT07527039RecruitingPhase 4
Nerve Block for Pain Relief During Breast Reduction Surgery
This study tests a special numbing technique (pectoral block) to help control pain after breast reduction surgery in women with very large breasts causing symptoms like neck, shoulder, or back pain. The goal is to see if this nerve block reduces pain better than standard pain control methods.
Roanoke, VirginiaAges 18–75 - NCT07244068Recruiting
Mat Pilates for kids with upper crossed syndrome
This trial tests if Mat Pilates can reduce pain and improve posture in school-going children with a specific forward head and rounded shoulder condition called upper crossed syndrome. It may help your child feel better and stand straighter.
Lahore, Punjab ProvinceAges 8–16 - NCT06761924Recruiting
Ultrasound-guided nerve block for shingles pain
This study tests whether an ultrasound-guided nerve block can help control pain from shingles (herpetic neuralgia). It may offer a way to target the pain more precisely.
Banī Suwayf, Beni Suweif GovernorateAges 18–70 - NCT07642583Enrolling by invitation
Dry Needling and Exercise for Achilles Tendon Pain
This study tests whether a combination of dry needling (a technique using thin needles) plus exercise can relieve pain in the Achilles tendon (the cord at the back of your heel). If you have ongoing Achilles pain, this trial might help you find relief and return to activities like running or walking.
Fort Sam Houston, TexasAges 18–64 - NCT07600359Recruiting
Physical therapy techniques for sacroiliac joint pain
This study compares two hands-on physical therapy techniques to reduce lower back pain, improve walking, and restore function in people with sacroiliac joint dysfunction (a condition affecting the joint connecting your spine to your pelvis). You'll receive treatment and be assessed to see which technique works better.
Islamabad, Punjab ProvinceAges 25–45 - NCT07622823Recruiting
Nerve Blocks to Reduce Pain After Heart Surgery
This study tests whether special numbing injections around nerves (called fascial plane blocks) can help reduce pain and improve recovery after planned heart surgery. The goal is to see if this technique helps patients manage pain better and recover faster.
AntalyaAges 18 years+ - NCT07112742Enrolling by invitation
Laser and exercise for thumb arthritis
This study tests if a special laser treatment plus hand exercises can reduce pain and improve function in people with thumb arthritis. It compares the laser to a placebo laser, so you won't know which group you're in.
KayseriAges 45–75 - NCT06185829Recruiting
Hypnosis versus sedation for hand surgery
This trial compares two ways to help you relax during hand surgery: hypnoanalgesia (using focused attention and suggestions) versus standard sedation. It aims to see which method provides better comfort and recovery.
Champigny-sur-MarneAges 18–80 - NCT06200662Recruiting
Maternal Comfort for Pain Relief During Blood Draw in Preemies
This study tests whether a mother's comforting actions (like holding, talking, or breastfeeding) can reduce pain in very premature babies during a blood draw. It may help your baby feel less pain without extra medicine.
Strasbourg, Bas-RhinAges 7 months–8 months - NCT07623304Recruiting
Exercise guidance system after spinal fusion surgery
This study tests a computer system that guides exercise recovery after spine surgery. It aims to help you heal better and move more safely at home using your WiFi connection.
Nantong, JiangsuAges 18–65 - NCT07081009Recruiting
Heart injury after planned back surgery study
This study is looking at whether patients having planned lower back surgery experience any heart stress afterward. It aims to understand how common this is and what might help protect the heart.
AnkaraAges 18 years+
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,749 recruiting pain medicine studies from the U.S. registry right now, out of 6,757 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.