Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,578 recruiting studies in this area right now.
By phase
- Not applicable2,954
- Phase 4240
- Phase 2129
- Phase 3103
- Phase 193
- Phase 2/Phase 337
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University84
- Cairo University59
- Beijing Tiantan Hospital34
- Tanta University33
- Ain Shams University28
- Foundation University Islamabad28
- Mayo Clinic25
- VA Office of Research and Development23
- Hacettepe University22
- Stanford University21
Where studies are running
- California151
- New York79
- Massachusetts65
- Florida64
- Texas50
- North Carolina41
- Illinois40
- Maryland39
- Ohio39
- Minnesota37
Recruiting studies3,578 total
- NCT07502209Recruiting
Two types of nerve treatment for chronic shoulder pain
This study compares two methods of treating chronic shoulder pain by using a needle to deliver a special type of electrical pulse to a nerve in the shoulder. The goal is to find which method provides better pain relief for people with shoulder pain from a rotator cuff problem.
AnkaraAges 40–80 - NCT07504120Recruiting
Home Pilates for people with multiple sclerosis
This study tests whether doing Pilates exercises from home, through online video sessions, can improve physical and mental well-being in people with mild to moderate multiple sclerosis. If you are fairly mobile and not very active, this could be a gentle way to increase exercise and feel better.
Chicago, IllinoisAges 18 years+ - NCT07504991Recruiting
Radiofrequency and ultrasound for pain after childbirth
This trial tests whether combining radiofrequency with ultrasound can reduce pain during sex after having a baby. It may help women who have had moderate to severe pain for a while after a vaginal delivery.
Tarragona, TARRAGONAAges 18–50 - NCT07502612Recruiting
Spinal cord stimulation medication tapering study
This study tests whether lowering pain medication can improve how well spinal cord stimulation works. It is for people who already take certain pain medicines and are scheduled to try a spinal cord stimulator.
WilrijkAges 18 years+ - NCT07502573Enrolling by invitation
Comparing two exercise programs for piriformis syndrome
This trial compares a home exercise program with a telerehabilitation program for people with piriformis syndrome. Researchers want to see which approach helps reduce pain and improve function better.
Ankara, KeciorenAges 18–45 - NCT07502742Recruiting
Pain in aging athletes and nonathletes
This study looks at how pain affects older adults who are either current master's athletes, former competitive athletes, or nonathletes. It aims to understand why some people have more pain and what helps them stay active.
Milwaukee, WisconsinAges 35–65 - NCT07506018Recruiting
MucoLock for mouth pain caused by stomatitis
This study tests a new mouth rinse, MucoLock, to see if it can help people with severe mouth pain (stomatitis). If you have burning or painful mouth sores that rate very high on a pain scale, this trial may offer a new treatment option.
Miami, FloridaAges 18 years+ - NCT07501416Recruiting
High-Intensity Laser for Shoulder Pain After Stroke
This study tests whether a high-intensity laser can safely reduce shoulder pain in people who have had a stroke. If you are between 30 and 75, had a stroke in the last 6 months, and have moderate or worse shoulder pain on your weak side, you may be able to join.
Kütahya, CenterAges 30–75 - NCT07501767Recruiting
Online exercise program for remote workers with back or neck pain
This study tests if a physiotherapist-led online exercise program can help remote workers with back or neck pain caused by long hours of sitting. It may improve your posture and reduce discomfort.
IstanbulAges 18 years+ - NCT07502157Recruiting
Massage for pain and anxiety during first cancer infusion
This study tests whether massage therapy can help reduce pain and anxiety in people with gynecologic cancer who are getting their first infusion treatment. You may be eligible if you are about to receive your first infusion and haven't had any in the past 2 years.
Lexington, KentuckyAges 18–85 - NCT05009394Recruiting
Surgery options for long-term pain after limb amputation
This trial studies different surgical approaches to reduce persistent pain in the leftover part of an amputated limb. You may be able to join if your post-amputation pain has lasted more than a year and your pain level stays high despite stable pain treatments and prosthesis use.
Chicago, IllinoisAges 18 years+ - NCT06531928Recruiting
Chest tube removal and anxiety after lung surgery
This study looks at whether the way a chest tube is removed after lung surgery affects how anxious patients feel. If you had keyhole lung surgery with one chest tube, this trial may help understand your experience.
Ankara, KeçiörenAges 18–65 - NCT06766240Recruiting
MRI for low back pain in middle-aged women
This trial is studying how well MRI can evaluate low back pain in women between 40 and 60 years old. It may help doctors better understand the cause of your pain.
SohagAges 40–60 - NCT06767280Recruiting
Testing calf muscle in chronic nerve pain patients
This study looks at how a muscle in your calf (gastrocnemius) responds to a gentle electrical test in people with long-term nerve pain from the lower back. It aims to learn more about how the condition affects muscle function, which could help improve future treatments.
Sixth of October, Giza GovernorateAges 18–55 - NCT06765772Recruiting
Nerve blocks for pain relief during tummy tuck surgery
This trial compares two types of nerve blocks (with numbing medicine) to reduce pain during and after tummy tuck surgery. The goal is to see if combining two blocks works better than one block alone.
Cairo, Cairo GovernorateAges 21–60 - NCT07493213Recruiting
Ultrasound-guided shoulder injections for frozen shoulder
This study tests whether ultrasound-guided injections into the shoulder can improve pain and movement in people with frozen shoulder. It may help if you have had shoulder pain for at least 3 months and other treatments haven't worked well.
Konya, SelçukluAges 18–75 - NCT07493226Recruiting
NSAIDs for Frozen Shoulder Pain Study
This study tests different types of nonsteroidal anti-inflammatory drugs (NSAIDs) to see which works best for people with frozen shoulder. It may help you if you have ongoing shoulder pain and stiffness without other shoulder injuries.
Konya, SelçukluAges 18–75 - NCT07493473Recruiting
Comparing two injections for rib fracture pain
This trial tests two different numbing injections for people with broken ribs on one side of the chest. The goal is to find which injection works better to reduce pain without the need for a breathing machine.
Zagazig, Sharqia ProvinceAges 21–60 - NCT07496203Recruiting
BETY program after knee injections for osteoarthritis
This trial tests if a special exercise and education program called BETY helps people with knee osteoarthritis feel better after getting a knee injection. You may qualify if you had a knee injection in the last month and have moderate knee arthritis.
Ankara, SamanpazarıAges 18 years+ - NCT07498140Recruiting
Epidural steroid injection for leg and back pain
This study is testing a treatment that involves an injection to reduce nerve-related leg and back pain. It looks at how much information about the procedure affects a patient's outlook and pain relief.
Chicago, IllinoisAges Any age - NCT07491354Recruiting
Predicting chronic pain after ICU trauma
This study looks at how biological, psychological, and social factors might help predict long-term pain after a traumatic injury that required ICU care. If you are an adult with a serious injury and at least one broken bone, you may be eligible.
MontpellierAges 18 years+ - NCT07497711RecruitingPhase 2/Phase 3
Virtual treatment for menstrual cramps
This study tests a virtual (app-based) approach to help manage menstrual cramps. It is for people with regular periods who have moderate to severe cramp pain and want to try a non-medication option.
SingaporeAges 16–35 - NCT07496983Recruiting
Using platelet-rich plasma (PRP) for tennis elbow
This study tests a treatment for tennis elbow called platelet-rich plasma (PRP), which uses your own blood to help the tendon heal. It looks at who benefits most from a PRP injection given within the last 48 hours.
PloemeurAges 18 years+ - NCT07491146RecruitingPhase 2
Study of HSK55718 for pain after abdominal surgery
This trial tests a new medicine, HSK55718, to see if it safely reduces pain after planned abdominal surgery. It is for adults who have moderate or severe pain after surgery and are otherwise in good health.
Changsha, HunanAges 18 years+
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,578 recruiting pain medicine studies from the U.S. registry right now, out of 6,493 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.