Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,756 recruiting studies in this area right now.
By phase
- Not applicable3,101
- Phase 4252
- Phase 2145
- Phase 3104
- Phase 197
- Phase 2/Phase 335
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University96
- Cairo University62
- Beijing Tiantan Hospital34
- Ain Shams University31
- Tanta University29
- Mayo Clinic28
- Foundation University Islamabad26
- Stanford University24
- VA Office of Research and Development22
- Hacettepe University20
Where studies are running
- California160
- New York81
- Massachusetts68
- Florida63
- Texas52
- Ohio48
- Maryland42
- Minnesota42
- North Carolina38
- Illinois37
Recruiting studies3,755 total
- NCT07675863Recruiting
Communication delays and anesthesia in emergencies
This study tests how communication delays affect anesthesia responses during medical emergencies and ultrasound-guided procedures. It may help identify ways to improve teamwork and safety in critical situations.
Halifax, Nova ScotiaAges Any age - NCT07642193Recruiting
Nerve Blocks for Open Kidney Removal Surgery Pain
This trial compares two types of numbing injections (nerve blocks) given during kidney removal surgery to see which better controls pain afterward. Both are alternatives to general anesthesia alone.
CairoAges 18 years+ - NCT07681661Recruiting
Massage Gun vs Deep Massage for Shoulder Knots
This study compares using a handheld massage device (like a massage gun) with deep pressure massage to treat painful knots in the upper shoulder muscle. It may help people with moderate to severe neck or shoulder pain who have not had recent treatment.
IslamabadAges 24–45 - NCT07642596Recruiting
Root Canal Treatment Methods and Post-Procedure Pain
This study compares two different techniques for cleaning and shaping root canals (the nerve chambers inside teeth) to see which one causes less pain after treatment. If you have a dead nerve in a back lower tooth, this trial may help us understand the best way to treat it with minimal discomfort.
Eskişehir, OdunpazarıAges 18–65 - NCT07639281Enrolling by invitation
Opioid Education for Ventral Hernia Repair Surgery
This study teaches patients about opioid pain medication before hernia repair surgery. It aims to help patients make informed decisions about pain management and understand safer opioid use.
Lexington, KentuckyAges 18–85 - NCT07587203Enrolling by invitation
Numbing medication for shoulder surgery and breathing
This trial compares two types of numbing medications (liposomal bupivacaine and standard bupivacaine) given as a nerve block for shoulder surgery. Researchers want to see which one works better for pain relief and causes fewer problems with your breathing afterward.
Nanjing, JiangsuAges 18–80 - NCT07604506Enrolling by invitation
Ultrasound nerve block training for junior emergency doctors
This study teaches junior doctors in emergency medicine how to use ultrasound to safely perform nerve blocks—a pain-relief technique. Researchers will compare learning with a low-cost practice model to see if it works as well as expensive alternatives.
Kubang Kerian, KelantanAges Any age - NCT07569705Recruiting
Nerve Stimulation to Help Breathing After Weight-Loss Surgery
This trial tests whether electrical nerve stimulation (a non-invasive, pain-relieving technique) can help improve breathing problems that sometimes occur after weight-loss surgery. The study measures how well your diaphragm—the muscle that helps you breathe—works after the procedure.
CairoAges 20–60 - NCT07531537Recruiting
Breathing exercises versus neck muscle training for neck pain
This study compares two types of exercises—breathing exercises and deep neck muscle training—to see which works better for people with long-term neck pain. You'll do one type of exercise program to help relieve your pain and improve function.
ZagazigAges 18–35 - NCT07600437Recruiting
Muscle and Joint Problems in Musicians Study
This research study examines how common muscle, joint, and bone problems are among people who play musical instruments. Researchers will ask you questions and may do physical assessments to understand which musicians are most affected and why.
Multiple LocationsAges 18 years+ - NCT07602452Recruiting
Pain Relief Methods After Colorectal Surgery
This study compares two different numbing techniques (nerve blocks) to help manage pain after open colorectal surgery. Both methods are injected near muscles in your abdomen to reduce the need for strong painkillers after surgery.
CairoAges 18–75 - NCT07603154Enrolling by invitation
Massage therapy for superior cluneal nerve pinching
This trial tests a specific massage technique called 'Fenjin Tuina' for treating superior cluneal nerve entrapment syndrome, a condition where a nerve in the lower back and hip area becomes pinched or compressed. The study aims to see if this traditional Chinese massage approach can reduce pain and improve function.
Guangzhou, GuangdongAges 18–70 - NCT07597343Recruiting
Helping You Stick With Hip Pain Exercise Treatment
This study tests new ways to help people with lateral hip pain (pain on the outer side of the hip) stay motivated and consistent with their exercise program. The goal is to understand what helps patients do their exercises regularly so they can feel better.
Leicester, LeictershaireAges 18 years+ - NCT07539467Enrolling by invitation
Nerve Block and Tourniquet for Knee Surgery Pain Relief
This trial tests whether a nerve block (numbing injection near the thigh) combined with a tourniquet (pressure cuff) after knee replacement surgery reduces pain better than standard care. If it works, it could help patients recover more comfortably with less need for strong pain medications.
AnkaraAges 40–85 - NCT07601750Enrolling by invitationPhase 4
Local Anesthetic Study for Skin Cancer Surgery
This study tests local anesthetics (numbing medicines) used during Mohs micrographic surgery, a specialized procedure for skin cancer. Researchers want to understand how well these numbing agents work and improve patient comfort during the procedure.
Dallas, TexasAges 18–89 - NCT07602933Recruiting
Light Therapy for Muscle Fatigue from Electrical Stimulation
This study tests whether light therapy can reduce muscle fatigue and damage caused by electrical muscle stimulation. Researchers want to see if this non-invasive light treatment helps muscles recover faster.
Porto Alegre, Rio Grande do SulAges 18–45 - NCT07573553Recruiting
Rib Mobilization and Posture Exercises for Upper Crossed Syndrome
This study tests whether combining rib mobilization (hands-on therapy to improve rib movement) with posture-correction exercises can reduce neck pain and improve posture in people with upper crossed syndrome (a postural condition causing rounded shoulders and forward head tilt). It may help you understand if this combination therapy works better than standard treatment.
Chak Six Hundred Twenty-four, Khyber PakhtunkhwatAges 20–45 - NCT07603921Recruiting
Local Pain Relief Injection During Lung Surgery
This study tests whether injecting a numbing medicine and anti-inflammatory steroid around the surgical area before lung surgery reduces pain after the procedure. If it works, it could help patients recover more comfortably after thoracoscopic lung surgery (minimally invasive lung surgery using small cameras).
Beijing, Beijing MunicipalityAges 18–64 - NCT07586397Recruiting
Hip Pain Treatment Study With Physical Activity Focus
This study tests a new approach to treating long-lasting hip pain that combines psychology and exercise. It's designed for people whose hip pain is affected by worry or stress, and who aren't as physically active as they'd like to be.
Boston, MassachusettsAges 18 years+ - NCT07593235Recruiting
Treating Forward Head Posture with Two Physical Therapy Techniques
This study compares two hands-on treatment methods for forward head posture—a common problem where your head juts forward. Researchers want to see which technique works better at improving your posture and reducing strain on your neck and upper back.
Islamabad, Punjab ProvinceAges 18–40 - NCT07544576Enrolling by invitationPhase 4
Knee Arthritis Injection: Two Injection Methods Compared
This study compares two ways of injecting a steroid medication into arthritic knees: using landmark guidance (traditional method) with a higher dose versus ultrasound guidance (imaging) with a lower dose. The goal is to see which approach works better to reduce knee pain and improve function.
Ventura, CaliforniaAges 50 years+ - NCT07595679Recruiting
Pain Relief Methods for Gallbladder Surgery
This study compares two types of numbing injections given during laparoscopic gallbladder removal surgery to see which one reduces the need for strong pain medications during the procedure. You would receive one of these two injection methods as part of your anesthesia care.
Ankara, YenimahalleAges 18–80 - NCT07604948Recruiting
Blood Flow Restriction Training for Basketball Recovery
This study tests whether briefly restricting blood flow to the legs (using an arm cuff on the thigh) can help male basketball players recover faster and improve leg strength after games. Researchers want to see if this technique, called ischemic preconditioning, reduces fatigue and speeds healing.
Guangzhou, GuangdongAges 18–25 - NCT07501416Recruiting
High-Intensity Laser for Shoulder Pain After Stroke
This study tests whether a high-intensity laser can safely reduce shoulder pain in people who have had a stroke. If you are between 30 and 75, had a stroke in the last 6 months, and have moderate or worse shoulder pain on your weak side, you may be able to join.
KütahyaAges 30–75
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,756 recruiting pain medicine studies from the U.S. registry right now, out of 6,776 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.