Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,578 recruiting studies in this area right now.
By phase
- Not applicable2,954
- Phase 4240
- Phase 2129
- Phase 3103
- Phase 193
- Phase 2/Phase 337
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University84
- Cairo University59
- Beijing Tiantan Hospital34
- Tanta University33
- Ain Shams University28
- Foundation University Islamabad28
- Mayo Clinic25
- VA Office of Research and Development23
- Hacettepe University22
- Stanford University21
Where studies are running
- California151
- New York79
- Massachusetts65
- Florida64
- Texas50
- North Carolina41
- Illinois40
- Maryland39
- Ohio39
- Minnesota37
Recruiting studies3,578 total
- NCT06102733Recruiting
Pelvic pain study for women and men
This trial is testing treatments for chronic pelvic pain, sacroiliac pain, groin pain, tailbone pain, and piriformis pain. It may help people with persistent pain in these areas find relief.
Surrey, British ColumbiaAges 20–99 - NCT07459400Recruiting
Mud therapy for young adults with scoliosis back pain
This study tests whether adding mud therapy (peloidotherapy) to standard scoliosis exercises helps reduce pain and improve function in young adults with mild to moderate scoliosis. It may be a good fit if you have idiopathic scoliosis and ongoing back pain.
Istanbul, GaziosmanpasaAges 20–40 - NCT07459166RecruitingPhase 2
Testing a new drug for fentanyl overdose
This study tests a new drug, CS-1103, to see if it can safely help reverse the effects of fentanyl (a strong opioid) even after a naloxone block. Healthy volunteers who have used opioids before will be given fentanyl and then the study drug, while researchers monitor safety and how the drug works.
Glendale, CaliforniaAges 18–55 - NCT05447338Recruiting
Manual therapy for neck pain with limited neck motion
This trial tests whether hands-on/manual physical therapy helps people with neck pain and reduced neck movement. It may help improve motion and reduce symptoms if your neck pain fits the trial’s type and severity.
CórdobaAges 25–50 - NCT07456787Recruiting
Cold therapy after knee replacement surgery
This trial tests a cold therapy approach (cryopressotherapy) to improve recovery after total knee replacement. It may help reduce pain and swelling so you can move better sooner.
Milan, ItalyAges 18–80 - NCT07458256Recruiting
Liposomal bupivacaine for pain after laparoscopic surgery
This trial tests a long-acting painkiller injected during surgery to see if it reduces pain after keyhole (laparoscopic) procedures like gallbladder removal, hernia repair, or appendix removal. It may help you need fewer opioids and recover more comfortably.
Beijing, Beijing MunicipalityAges 18–64 - NCT07458282Recruiting
Testing a long-lasting numbing medicine for pain after laparoscopic surgery
This trial is testing if a special numbing medicine called liposomal bupivacaine, given as a nerve block during surgery, can help reduce pain after laparoscopic procedures like gallbladder removal or hernia repair. It might help you feel better with less need for strong painkillers.
Beijing, Beijing MunicipalityAges 18–64 - NCT07457788Recruiting
Forest Sounds During Chest Tube Removal
This study tests whether listening to virtual reality forest sounds can help people feel more comfortable while a chest tube is taken out. It may reduce pain or anxiety during this short procedure.
Istanbul, KadıköyAges 18 years+ - NCT07455565Recruiting
Pain monitoring with ANI after lumbar spine surgery
This study tests a new way to monitor pain after lower back surgery using a device called ANI, which tracks your body's response to pain. The goal is to see if this method helps doctors give you better pain relief.
Antalya, AntalyaAges 18–65 - NCT07458360Recruiting
Front block for better recovery after hip replacement
This study tests if a special nerve block called the front block (pericapsular nerve group block) improves recovery after hip replacement surgery. You may be eligible if you are having hip replacement under spinal anesthesia and do not have certain health issues.
KonyaAges 18 years+ - NCT07456137Enrolling by invitation
Studying MRI vs. X-ray for spine pain
This trial compares two types of CT scans (upright vs. lying down) to see which gives better images of the lower back. It may help doctors choose the best scan for spine problems.
Kansas City, KansasAges 18 years+ - NCT07457086Recruiting
Breathing technique for better sleep and recovery after bladder surgery
This trial tests whether a simple breathing pattern called 4-7-8 can help you sleep better, hurt less, and recover faster after transurethral resection of the bladder (a procedure to remove bladder tumors).
Mersin, TurkeyAges 18 years+ - NCT07458295Recruiting
Liposomal bupivacaine for pain after gynecologic cancer surgery
This trial tests whether a long-acting numbing medication (liposomal bupivacaine) injected into the abdominal wall can reduce pain after laparoscopic surgery for gynecologic cancer. If effective, it may help patients recover with less discomfort and fewer painkillers.
Beijing, Beijing MunicipalityAges 18–64 - NCT07461376Recruiting
A trial comparing two sleep medicines for children before surgery
This study tests two oral medicines given before surgery to help children relax and lower the need for stronger painkillers after the operation. It is for children having surgeries like hernia repair, circumcision, or hypospadias correction.
Cairo, Giza GovernorateAges 3–12 - NCT07458971Recruiting
AI-assisted assessment for thumb arthritis
This study tests a new way to assess thumb arthritis using an AI tool that looks at your overall health. It aims to predict your health profile and may help personalize your care.
AnkaraAges 25–74 - NCT07462364Recruiting
Using a kaleidoscope or cartoons for dental treatment in children
This study tests whether using a kaleidoscope or watching cartoons can help calm children during dental treatment that requires a numbing shot. It aims to find a simple way to make dental visits less scary.
Diyarbakır, DiyarbakırAges 7–12 - NCT07456657Recruiting
Lavender massage for pain and wrist mobility in rheumatoid arthritis
This trial tests whether lavender aromatherapy massage can reduce pain and improve wrist movement in people with rheumatoid arthritis. If you have stable RA and positive rheumatoid factor, you may be able to join.
Hillah, Babil GovernorateAges 20–60 - NCT07454993Recruiting
Music during colonoscopy study
This trial tests whether listening to music during a colonoscopy can make the procedure more comfortable. If you are having a routine colonoscopy without deep sedation, you may be able to join.
Esbjerg, Region SydAges 18 years+ - NCT06279650Recruiting
Self-hypnosis for chronic pain: follow-up interviews
This study asks people who took a self-hypnosis course for chronic pain about their experience. They will share their thoughts in an interview to help improve the program.
Montreal, QuebecAges 18 years+ - NCT06753500RecruitingPhase 4
Numbing medicine during gallbladder surgery
This trial tests whether giving a special numbing medicine during gallbladder surgery helps reduce pain. It is for adults having laparoscopic (minimally invasive) gallbladder removal.
Barranquilla, AtlantivoAges 18 years+ - NCT06796881Recruiting
Comparison of two therapies for long-term low back pain
This study compares two hands-on treatments for people with chronic low back pain. One uses special tools to massage tight muscles, while the other uses gentle pressure on muscle knots. Both aim to help you move better and feel less pain.
CairoAges 25–45 - NCT06794528Recruiting
Neck pain exercise program using mobile exergames
This trial tests if doing therapeutic exercises through fun mobile games (exergames) can help people with neck pain. You'll use your own smartphone or tablet to follow the program.
Palma de Mallorca, Balearic IslandsAges 18–70 - NCT06797414Recruiting
Pilates with or without vibration for upper cross syndrome
This study compares Pilates exercises with and without whole-body vibration (a platform that gently shakes your body) to see which better improves posture and pain in people with upper cross syndrome (a common pattern of rounded shoulders and forward head). It aims to find a more effective way to strengthen muscles and reduce discomfort.
Lahore, Punjab ProvinceAges 20–40 - NCT06796595Recruiting
Nerve recovery program for chronic pelvic nerve pain
This study tests a medical program designed to help nerves heal better after surgery for long-term pelvic or buttock nerve pain. It looks at results one year after a minimally invasive operation to free compressed nerves.
BordeauxAges 18 years+
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,578 recruiting pain medicine studies from the U.S. registry right now, out of 6,493 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.