Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,756 recruiting studies in this area right now.
By phase
- Not applicable3,101
- Phase 4252
- Phase 2145
- Phase 3104
- Phase 197
- Phase 2/Phase 335
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University96
- Cairo University62
- Beijing Tiantan Hospital34
- Ain Shams University31
- Tanta University29
- Mayo Clinic28
- Foundation University Islamabad26
- Stanford University24
- VA Office of Research and Development22
- Hacettepe University20
Where studies are running
- California160
- New York81
- Massachusetts68
- Florida63
- Texas52
- Ohio48
- Maryland42
- Minnesota42
- North Carolina38
- Illinois37
Recruiting studies3,755 total
- NCT07490366Recruiting
Exercise vs needle treatment for shoulder muscle pain
This study compares three treatments for long-term shoulder muscle pain: exercises, dry needling (tiny needles into tight muscle spots), and a numbing shot between muscle layers. It aims to find which works best for myofascial pain syndrome.
Istanbul, IstanbulAges 18–55 - NCT07515287Enrolling by invitation
Pilates for Back Pain Recovery in Middle-Aged Women
This study tests whether Pilates exercises can help women aged 45–60 with chronic lower back disc problems improve their balance, leg strength, and body awareness. Pilates focuses on core stability and controlled movement, which may help restore function lost due to the disc herniation.
Kahramanmaraş, onikişubatAges 45–60 - NCT07513740Recruiting
Pain relief methods for hip fracture surgery
This trial compares two different nerve-block techniques (pain-relief injections) to see which one works better for patients having surgery to repair a broken hip. Both methods numb the area around the hip so you feel less pain during and after surgery.
Erzincan, Merkez/TürkiyeAges 18–75 - NCT07511491Recruiting
Ondansetron lozenge vs IV for preventing shivering during C-section
This trial tests if an ondansetron lozenge (a tablet you dissolve in your mouth) works as well as ondansetron given through a vein to prevent shivering during cesarean section. Shivering is a common side effect of spinal anesthesia.
Tanta, El-GharbiaAges 18–40 - NCT07453498Recruiting
Nerve block for pain after hip replacement
This study tests if a specific nerve block (the psoas sheath block) helps reduce pain after hip replacement surgery. If you are having a hip replacement, you may be able to join and get this extra pain relief.
GalwayAges 18 years+ - NCT07522736Recruiting
Spinal anesthesia with dexmedetomidine for knee surgery
This trial tests adding dexmedetomidine (a calming medication) to bupivacaine (numbing medication) injected into the spine during knee surgery. The goal is to improve pain relief and recovery after surgery.
CairoAges 18–65 - NCT07474896Recruiting
Nerve-block techniques for shoulder surgery in older adults
This study tests whether certain nerve-block techniques for shoulder surgery can reduce side effects while still controlling pain. It is for people 65 and older having planned shoulder surgery with regional anesthesia.
PoznanAges 65–100 - NCT07517809Recruiting
Comparing two nerve-block techniques for arm surgery
This trial compares two different ultrasound-guided methods of numbing the nerves in your upper arm and shoulder for surgery on your hand, wrist, or forearm. The goal is to see which technique works better and is safer for patients.
CairoAges 21–65 - NCT07514013Recruiting
Olive Oil Extract for Knee Comfort and Function
This study tests whether a daily olive oil extract capsule can help improve knee comfort and function in adults with ongoing knee discomfort. Participants will track their symptoms and wear an activity monitor while taking the supplement.
San Francisco, CaliforniaAges 40–75 - NCT07373210Recruiting
Placebo pills for hip surgery pain in teens and young adults
This study tests whether taking placebo pills (pills with no active drug) can help manage pain after a specific hip surgery, called Bernese Periacetabular Osteotomy (PAO), in people with a hip condition called developmental dysplasia. The goal is to see if using placebos can reduce the need for pain medications and help with recovery.
San Francisco, CaliforniaAges 13–40 - NCT07382830Recruiting
Visual feedback exercises after lower back surgery
This trial tests if a special exercise program that uses visual feedback helps people recover better after surgery for a herniated disc in the lower back. It may improve your recovery and reduce pain.
AntalyaAges 18–65 - NCT07411521Recruiting
Comparing two pain relief methods after planned cesarean
This trial compares two ways to manage pain after a planned cesarean section: one combines a spinal and epidural injection, the other is a newer type of nerve block. The goal is to see which provides better pain relief with fewer side effects.
Bursa, NilüferAges 18–45 - NCT07383623Recruiting
Staples vs. stitches for episiotomy healing after first birth
This trial compares using surgical staples versus traditional stitches to repair an episiotomy (a cut made during childbirth) in women having their first vaginal birth. It aims to see which method causes less pain and helps the wound heal better.
Izmir, İzmirAges 18–49 - NCT07396051Recruiting
Exercise program for frail older adults after back fusion surgery
This trial tests whether a special exercise program after lower back fusion surgery can help prevent complications in older adults who are frail. If you are 75 or older and having your first small back fusion, this rehab might help you recover better.
Beijing, Beijing MunicipalityAges 75 years+ - NCT07435337RecruitingPhase 4
Pain medicine study for heart surgery patients
This trial tests two different pain medicines, nalbuphine and fentanyl, to see which one causes fewer changes in blood pressure and heart rate during the placement of a breathing tube for heart surgery.
Rawalpindi, Punjab ProvinceAges 40–60 - NCT07386379Recruiting
Propofol infusion for nausea after heart bypass surgery
This study tests whether a continuous infusion of propofol (a common anesthesia medicine) during and after heart bypass surgery can reduce postoperative nausea and vomiting. If you are having planned bypass surgery and meet basic health criteria, this trial may help find a better way to feel more comfortable after your operation.
Istanbul, Outside of the USAges 18 years+ - NCT07338825Enrolling by invitation
Ankle instability study for Egyptian soccer players
This study looks at how common ankle instability is among soccer players in Egypt. The goal is to understand how many players have ongoing ankle issues, which may help improve future training or treatment.
CairoAges 8–35 - NCT07351253Recruiting
Nerve block comparison for open appendix surgery
This study tests two types of nerve blocks (Erector Spinae Plane Block and Lateral Transversus Abdominis Plane Block) to see which provides better pain relief after open appendectomy. This could help reduce pain and the need for stronger painkillers after surgery.
Cairo, Cairo GovernorateAges 21 years+ - NCT07278375Recruiting
Comparing treatments for babies with opioid withdrawal
This study looks at different medicine approaches to treat newborns with opioid withdrawal (NOWS). It compares how well babies do with standard care and may help find the best way to manage symptoms and support recovery.
Birmingham, AlabamaAges birth+ - NCT07347067Recruiting
Trigger point injections for chronic migraine
This study tests if injecting medication into specific painful spots in your muscles (called trigger points) can help reduce chronic migraine pain. It may be an option if you've tried other treatments but still have significant pain.
Beijing, Beijing MunicipalityAges 18–65 - NCT07323043Recruiting
Comparing tegileridine and sufentanil for cough during anesthesia
This trial tests whether tegileridine causes less coughing than sufentanil when given as part of anesthesia for surgery. It aims to find a better painkiller option for patients having surgery with a breathing tube.
Lianyungang, JiangsuAges 18–65 - NCT07344727Recruiting
Can haskap berries help you recover after heavy squats?
This study tests whether taking haskap berries (a type of superfruit) before and after intense squat workouts can speed up your recovery and reduce soreness.
Bozeman, MontanaAges 18–35 - NCT07292662Recruiting
Comparing two nerve blocks for pain after planned cesarean
This study compares two types of pain-relieving nerve blocks (TAP block and ESP block) given during a planned cesarean section. It aims to find which one works better for controlling pain after surgery.
PadovaAges 18–45 - NCT07325058Recruiting
Ear nerve stimulation and pain study
This study tests whether a mild electrical stimulation of a nerve in your ear can change how you feel pain from a capsaicin (chili pepper) patch on your leg. It may help researchers understand how to treat pain without drugs.
AalborgAges 16–60
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,756 recruiting pain medicine studies from the U.S. registry right now, out of 6,776 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.