Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,578 recruiting studies in this area right now.
By phase
- Not applicable2,954
- Phase 4240
- Phase 2129
- Phase 3103
- Phase 193
- Phase 2/Phase 337
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University84
- Cairo University59
- Beijing Tiantan Hospital34
- Tanta University33
- Ain Shams University28
- Foundation University Islamabad28
- Mayo Clinic25
- VA Office of Research and Development23
- Hacettepe University22
- Stanford University21
Where studies are running
- California151
- New York79
- Massachusetts65
- Florida64
- Texas50
- North Carolina41
- Illinois40
- Maryland39
- Ohio39
- Minnesota37
Recruiting studies3,578 total
- NCT06875856Recruiting
Cailliet and Kendall exercises for neck pain relief
This study compares two types of exercises to see which is better at reducing long-lasting neck pain. If you have had moderate neck pain for over 3 months without arm pain, this may help you find the best way to feel better.
Lahore, Punjab ProvinceAges 18–40 - NCT04666714RecruitingPhase 3
Tested a new medicine to reduce diabetic nerve pain
This Phase 3 study tests Praga formulation to see if it safely reduces nerve pain caused by diabetes. You may qualify if you’re an adult with painful diabetic neuropathy and have certain symptom and pain scores on questionnaires.
Campinas, São PauloAges 18 years+ - NCT06155916Recruiting
Sleep and nerve pain: a pregabalin study
This study tests whether a nerve pain medication (pregabalin) helps people with long-term nerve pain sleep better. It involves brain scans to see how the medication affects the brain.
Helsinki, HUSAges 18–75 - NCT07303582RecruitingPhase 4
Freezing nerves to ease pain from muscle tightness
This study tests if freezing specific nerves (cryoneurolysis) can reduce pain caused by muscle tightness (spasticity) after a brain or spinal cord injury, or from multiple sclerosis. It is for people who already get Botox injections for this pain.
OxfordAges 18 years+ - NCT07301476Recruiting
Testing numbing medicine spread in a knee block
This trial checks how a numbing medicine moves during a common knee block for surgery. It may help doctors improve pain control after knee operations.
Boulogne-BillancourtAges 18 years+ - NCT07298109Recruiting
Diaphragm Release for Chronic Low Back Pain
This study tests if releasing tension in the diaphragm muscle can help reduce chronic low back pain. It may be a treatment option for people whose back pain has lasted at least 12 weeks and has no clear cause.
KarabükAges 18–65 - NCT07304076Recruiting
JHG002 Injection for Chronic Low Back Pain
This study tests if JHG002 injections (made from human placenta) are safe and effective for treating chronic low back pain. It may help people who have had low back pain for at least 6 months and rate their pain as a 5 or higher on a 0–10 scale.
Seoul, Gangdong-guAges 19–70 - NCT07304037Enrolling by invitation
Skin-to-skin contact after birth for pain and satisfaction
This study looks at whether holding your baby skin-to-skin right after birth can help reduce your pain, improve your satisfaction with the birth, and affect your vital signs. If you had a healthy, full-term pregnancy and a vaginal birth without pain medication, you may be able to join.
IstanbulAges 18 years+ - NCT07302048Recruiting
Mobile pain management support for kids with intellectual disabilities
This study tests a mobile program that helps manage pain in children and young adults with intellectual disabilities, autism, or multiple disabilities. It aims to see if the program improves pain relief and works well with their care team.
BrestAges Up to 24 years - NCT07304557Recruiting
Exercise therapy for jaw joint disorders
This study tests whether specific exercises can reduce pain and improve jaw and tongue function in people with temporomandibular joint disorder (TMD). It may help if you have jaw pain or clicking and have not had recent neck or jaw therapy.
Ankara, ALTINDAGAges 18–65 - NCT07301632RecruitingPhase 2
MDMA for severe chronic nerve pain
This trial tests if MDMA, combined with psychotherapy, can help people with severe chronic nerve pain that hasn't improved with standard treatments. You'll receive either MDMA or a placebo to see if it safely reduces pain and improves your quality of life.
Toronto, OntarioAges 18 years+ - NCT07305025Recruiting
Acupuncture for pelvic pain in endometriosis
This trial tests if electro-acupuncture can help reduce pelvic pain in women with suspected endometriosis. You would receive acupuncture treatments and be followed to see if your pain improves.
TrondheimAges 18–45 - NCT07297784Enrolling by invitation
Screen time and pain after tonsil removal in children
This study looks at whether children who use a lot of screens (like tablets, phones, or TV) feel more or less pain after tonsil surgery. It could help parents understand how media use affects recovery.
Tokat Province, Tokat ProvinceAges 4–11 - NCT07301177Recruiting
Magnetic stimulation for veterans with nerve pain after injury
This study tests whether a non-invasive magnetic stimulation treatment can help veterans with long-term nerve pain after an injury or surgery. It may offer a drug-free option to reduce pain and improve quality of life.
San Diego, CaliforniaAges 18 years+ - NCT07301970Recruiting
Remifentanil dosing in low-weight ICU patients
This study looks at how the sedative remifentanil works in critically ill patients who are underweight or normal weight. It aims to find the right dose for these patients while they are on a breathing machine in the ICU.
ShanghaiAges Any age - NCT07306312Enrolling by invitation
How thoughts affect low back pain with manual therapy
This study looks at how your thoughts and feelings about your chronic low back pain affect your pain and ability to move, during a course of manual therapy (hands-on treatment by a therapist). It may help you understand if your mindset influences your recovery.
AthensAges 18–65 - NCT07297459Enrolling by invitation
Surgery options for a jaw joint problem
This trial compares two types of surgery to treat a common jaw joint problem where the disc slips out of place. It looks at which procedure works better for reducing pain and improving function.
StockholmAges 18 years+ - NCT07304401Recruiting
Closed-loop spinal cord stimulation for chemo-related nerve pain
This trial tests whether a new type of spinal cord stimulator (SCS) can reduce pain caused by chemotherapy. If you have lasting nerve pain after cancer treatment and standard pain medications haven't helped, this device might offer relief.
ArnhemAges 18 years+ - NCT07297901Enrolling by invitation
Breathing app study for migraine relief
This trial tests a smartphone-based breathing program to help reduce migraines. It uses heart rate data to guide breathing exercises tailored to you.
Phoenix, ArizonaAges 18 years+ - NCT07300995Recruiting
Pain coping skills for older women with breast cancer
This study tests a behavioral program to help older women with breast cancer learn skills to cope with pain. The program is done through video or phone sessions.
Durham, North CarolinaAges 55 years+ - NCT07298941RecruitingPhase 2
Sleep treatment to help with chronic low back pain
This study tests if improving sleep can help people with chronic low back pain feel better and cope with pain. It involves a sleep-focused treatment program and looks at how it affects your overall well-being.
Charlottesville, VirginiaAges 18 years+ - NCT07302958Recruiting
Comparing remote, in-person, and mixed exercise for neck pain
This trial compares three ways to treat chronic neck pain: doing exercises at home with remote guidance, doing them in a clinic with a therapist, or a mix of both. It aims to find which method works best for people with ongoing neck pain.
CairoAges 20–45 - NCT07288021RecruitingPhase 4
Topical anesthesia for balloon catheter insertion
This trial tests whether applying a numbing cream to the cervix before inserting a balloon catheter makes the procedure less painful for women being induced into labor. If you are scheduled for labor induction with a balloon, this study may help reduce your discomfort.
HaifaAges 18 years+ - NCT07293780Recruiting
TMS for nerve pain after spinal cord injury
This trial tests whether transcranial magnetic stimulation (TMS), a non-invasive brain stimulation, can help relieve nerve pain in people with spinal cord injury. It is for those who have had chronic nerve pain for at least 6 months that hasn't improved with standard treatments.
Ankara, YenimahalleAges 18–65
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,578 recruiting pain medicine studies from the U.S. registry right now, out of 6,493 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.