Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,578 recruiting studies in this area right now.
By phase
- Not applicable2,954
- Phase 4240
- Phase 2129
- Phase 3103
- Phase 193
- Phase 2/Phase 337
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University84
- Cairo University59
- Beijing Tiantan Hospital34
- Tanta University33
- Ain Shams University28
- Foundation University Islamabad28
- Mayo Clinic25
- VA Office of Research and Development23
- Hacettepe University22
- Stanford University21
Where studies are running
- California151
- New York79
- Massachusetts65
- Florida64
- Texas50
- North Carolina41
- Illinois40
- Maryland39
- Ohio39
- Minnesota37
Recruiting studies3,578 total
- NCT07289321Enrolling by invitation
Pain relief study for robotic prostate surgery
This trial tests if adding tramadol and magnesium to a local anesthetic (ropivacaine) improves pain control after robotic prostate removal. It may help reduce the need for strong painkillers after surgery.
Athens, AtticaAges 40–80 - NCT07289893Recruiting
Kettlebell training for shoulder pain in athletes
This trial tests whether kettlebell training can help people with long-lasting shoulder pain caused by rotator cuff tendon problems or small tears. You would do kettlebell exercises and see if your pain and strength improve.
AnkaraAges 18–35 - NCT07294651Recruiting
Needle treatment for chronic neck pain
This trial is testing a procedure called percutaneous electrolysis, where a tiny needle is used to treat painful trigger points in the upper neck muscles. It may help people with long-lasting neck pain.
SivasAges 18–70 - NCT07290361Recruiting
Physical therapy for spine pain in primary care
This trial tests a program that connects people with spine pain (neck or back pain) from their primary care clinic to a physical therapist. The goal is to see if this approach helps patients get more timely and effective care.
San Diego, CaliforniaAges 18 years+ - NCT07296926Recruiting
Numbing injection comparison for wisdom tooth removal
This study compares two numbing methods for removing a lower wisdom tooth. One is an injection near the tooth and the other is a nerve block. It aims to see which works better and may be more comfortable.
IslamabadAges 18–45 - NCT07290205RecruitingEarly Phase 1
Remimazolam brain imaging study
This study uses brain scans to see how a new sedative called remimazolam affects the brain in healthy adults. It will help researchers understand the drug's effects and ensure it's safe.
Pittsburgh, PennsylvaniaAges 18–59 - NCT07290517Recruiting
Using Carevix device for pain during IUD insertion
This trial tests if a special device called Carevix can make IUD insertion less painful. You may be able to join if you are scheduled to get an IUD placed and your provider plans to use the Carevix device.
Indianapolis, IndianaAges 18 years+ - NCT07295457Recruiting
Exercise to prevent pain from hormone therapy in breast cancer
This trial tests whether starting a gentle exercise program early can help prevent or reduce joint and muscle pain caused by aromatase inhibitors (a common breast cancer medicine). It is for women with hormone-sensitive breast cancer who are not yet experiencing severe pain from their treatment.
LyonAges 18–75 - NCT07289737Recruiting
Comparing two spine surgeries for a slipped backbone
This study compares two types of spine surgery for a common condition where a lower back bone slips forward. It aims to see which surgery works better to relieve pain and improve function.
Yiwu, ZhejiangAges 50–90 - NCT07294118RecruitingPhase 2
Lidocaine and steroids for pain after brain bleed
This trial tests whether giving a numbing medicine (lidocaine) and steroids into the artery that covers the brain can help reduce pain after a brain bleed. It may be an option for people with a specific type of bleeding who have not had certain brain surgeries or procedures.
Galveston, TexasAges 18–100 - NCT07293975Recruiting
Pain relief during brace removal with TENS or vibration
This study tests two drug-free methods—gentle electrical stimulation (TENS) and high-frequency vibration—to see if they can reduce pain when braces are removed.
BaghdadAges 15–35 - NCT07291388Recruiting
Retrolaminar block for lumbar fusion with multimodal pain control
This study tests whether adding a retrolaminar block (a type of back injection) to standard pain medicines helps reduce pain after lumbar spine fusion surgery. It may help you recover with less need for strong painkillers.
Santiago, Santiago MetropolitanAges 18–75 - NCT07296653RecruitingEarly Phase 1
Prolotherapy for chronic low back pain
This trial tests a treatment called prolotherapy, which uses injections of a sugar solution into specific acupuncture points to help relieve chronic low back pain. It is for people who have had low back pain for at least 3 months, have not had previous back surgery, and have not received similar injections recently.
Athens, AtticaAges 35 years+ - NCT07294092RecruitingEarly Phase 1
Brain imaging study of ketamine and propofol
This study uses MRI scans to see how two common sedatives, ketamine and propofol, affect brain activity. It may help explain how these drugs work differently in the brain.
Pittsburgh, PennsylvaniaAges 18–59 - NCT07290660Recruiting
Motor imagery and exercise for shoulder pain
This study tests whether combining mental movement training with targeted exercises can reduce shoulder pain caused by impingement syndrome. It aims to improve your shoulder function without surgery.
IstanbulAges 25–65 - NCT07290881Recruiting
Comparing two nerve blocks for hernia surgery pain relief
This trial compares two types of nerve blocks (anterior iliac block and ilioinguinal-iliohypogastric block) to see which provides better pain relief after inguinal hernia surgery. If you are having this surgery, joining could help doctors understand the best way to manage your pain.
Şanliurfa, Hali̇li̇yeAges 18–65 - NCT07295587Enrolling by invitation
Headache impact study for Libbs employees
This trial looks at how headaches affect employees at Libbs Pharmaceutical. It uses health data from the Dr. Cefaleia app to understand the burden of headaches at work.
São Paulo, São PauloAges Any age - NCT07289776RecruitingPhase 1
Testing a new medicine in healthy volunteers
This first-in-human trial tests a new medicine called GRT7041 in healthy people to see how safe it is and how it works in the body. It helps doctors understand the right dose and any side effects before testing in patients.
ChristchurchAges 18–60 - NCT06186973Recruiting
Fetal and newborn heart assessment during labor
This study checks how well a baby's heart works during labor and right after birth. It uses a special monitor (CTG with STAN) to see if the baby's heart responds normally to the stress of labor.
OsloAges birth–1 hour - NCT06746922Recruiting
Brain stimulation for fibromyalgia pain
This study tests a type of non-invasive brain stimulation called Intermittent Theta Burst Stimulation (iTBS) to see if it can help reduce pain and improve daily function in people with fibromyalgia. It may offer a new option for managing your pain without medication changes.
Izmir, KarabaglarAges 18–65 - NCT06777875Recruiting
How genes affect pain after surgery in children
This trial looks at how certain genes may affect how children feel pain after surgery. The goal is to understand if differences in your DNA can help doctors manage pain better for each child.
BeirutAges 8–18 - NCT03382938Recruiting
Dexmedetomidine injected into C-section wounds
This trial studies whether a specific numbing/comfort medicine (dexmedetomidine) injected into the wound area during a C-section can improve recovery or reduce symptoms after surgery. You may be able to take part if you are a low-risk pregnancy and meet safety requirements.
Athens, OtherAges 18–40 - NCT05817786Recruiting
Electrical nerve stimulation for persistent arm nerve pain
This trial tests whether stimulating the nerve roots in the shoulder area can reduce long-lasting nerve pain in one arm. It may help people whose arm pain has not improved with standard nerve-pain treatments.
Lyon, FranceAges 1.5 years–80 years - NCT07285083Recruiting
Pain relief after abdominal surgery: comparing two numbing medicines
This study compares two numbing medicines (bupivacaine alone vs. bupivacaine plus dexmedetomidine) to see which provides better pain relief after abdominal surgery. If you are having a planned abdominal operation, this trial may help improve your recovery comfort.
Rahim Yar Khan, Punjab ProvinceAges 21–45
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,578 recruiting pain medicine studies from the U.S. registry right now, out of 6,493 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.