Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,578 recruiting studies in this area right now.
By phase
- Not applicable2,954
- Phase 4240
- Phase 2129
- Phase 3103
- Phase 193
- Phase 2/Phase 337
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University84
- Cairo University59
- Beijing Tiantan Hospital34
- Tanta University33
- Ain Shams University28
- Foundation University Islamabad28
- Mayo Clinic25
- VA Office of Research and Development23
- Hacettepe University22
- Stanford University21
Where studies are running
- California151
- New York79
- Massachusetts65
- Florida64
- Texas50
- North Carolina41
- Illinois40
- Maryland39
- Ohio39
- Minnesota37
Recruiting studies3,578 total
- NCT01218776Recruiting
Survey study for people with acute heart symptoms
This study is an international survey about acute coronary syndromes, which are sudden signs of heart-related problems. Your answers can help researchers better understand symptoms and care needs after these events.
Bologna, Emilia-RomagnaAges 18 years+ - NCT06863649Recruiting
Games for shoulder and arm pain after a stroke
This trial tests if doing fun, non-immersive video game–like exercises for a short time can help reduce chronic pain in the shoulder or arm after a stroke. It looks at whether these exercises can improve arm movement and make daily activities feel easier.
Exeter, DevonAges 18 years+ - NCT06913088Recruiting
Ultrasound bubbles bandage for hand arthritis
This trial tests a special bandage that uses ultrasound and tiny bubbles to treat arthritis pain and stiffness in your hands. If you have hand arthritis with at least three painful finger or wrist joints, you may be able to join.
Taichung, TaichungAges 20 years+ - NCT06933004Recruiting
Long-term follow-up after lumbar spine surgery
This study will follow patients who have surgery for lower back problems. It aims to learn about their long-term recovery and outcomes.
TaipeiAges 20–80 - NCT04883411Recruiting
First-in-human test of new cervical spine plate and cage
This study tests a new implanted metal plate and cage to treat problems in the neck caused by worn spinal discs and nerve or spinal cord compression. It is aimed at people whose symptoms have not improved with non-surgical care for at least 6 weeks (or who have worsening nerve/spinal cord symptoms).
Union, New JerseyAges 22–79 - NCT06933680Recruiting
Nerve block for jaw surgery pain relief
This trial tests whether a nerve block behind the nose can reduce pain after double-jaw surgery. It may help patients who are having this surgery and want better pain control.
Istanbul, FatihAges 18–45 - NCT06933303Recruiting
Distraction for pain in children with burns
This trial tests if using a kaleidoscope can help distract children aged 7-12 from pain during burn dressing changes, in a setting where pain medicine is not usually given. The goal is to see if this simple tool can reduce pain without extra medication.
Empangeni, KwaZulu-NatalAges 7–12 - NCT06935708RecruitingPhase 4
Comparing morphine to epidural pain relief for colon surgery
This study compares two pain relief methods—morphine given through a spinal needle versus pain medicine delivered through a tiny tube in the back—after colorectal cancer surgery. It aims to see which approach works better for controlling pain.
SplitAges 18–80 - NCT06936995Recruiting
Comparing pain relief methods for ACL surgery recovery
This trial tests two ways to manage pain after ACL reconstruction: a combination of medications (multimodal analgesia) versus a nerve block in the thigh (femoral block). The goal is to see which approach provides better pain control and recovery.
AnkaraAges 18–65 - NCT07196397Recruiting
Polish Registry of Heart Nerve Procedures
This registry tracks people who have had or plan to have a procedure that changes the nerves controlling heart rate, such as cardioneuroablation. It aims to better understand and treat conditions like inappropriate tachycardia, POTS, and fainting spells.
RzeszówAges 18 years+ - NCT06665438RecruitingPhase 3
Pain relief after knee arthroscopy: numbing injection with added medication
This trial tests whether adding dexmedetomidine to a numbing injection (bupivacaine) inside the knee joint provides better pain relief after arthroscopic ACL reconstruction. It aims to help patients recover more comfortably after surgery.
AsyutAges 18–65 - NCT07195162Recruiting
Testing a digital tool for pain management
This trial is testing a digital workflow system to help doctors manage pain. It may be a good fit if you've had pain lasting at least a month.
HaifaAges 18–80 - NCT07195422Recruiting
Study of a new device for low back pain relief
This trial tests a wearable device called Japet.W+ to see if it can help reduce chronic low back pain. It might be an option for people who have had lower back pain for a long time and are looking for non-surgical relief.
Clermont-FerrandAges 18–80 - NCT05648253Recruiting
Hyivy device after pelvic radiation for vaginal health
This study checks whether a special vaginal device (Hyivy) is safe and workable after pelvic radiation for certain cancers. You may be asked to use it for 12 weeks to help with vaginal changes after treatment, and you would visit the study team regularly.
Kitchener, OntarioAges 18 years+ - NCT06262893Recruiting
Comparing nerve blocks for shoulder surgery
This study compares two types of nerve blocks for pain relief during shoulder surgery. It tests whether adding a common steroid (dexamethasone) to one block improves pain control.
AsyutAges 18–75 - NCT06544525Recruiting
Pain test to predict physical therapy results for back pain
This trial tests whether a simple pain test can predict how much you will improve with physical therapy for chronic low back pain. It looks at how your body naturally handles pain, which may help tailor your treatment.
Fort Sam Houston, TexasAges 18–64 - NCT07193836Enrolling by invitation
Lidocaine for easier recovery after laparoscopic surgery
This study tests whether giving lidocaine (a numbing medicine) through an IV can help you wake up more smoothly and with less discomfort after laparoscopic gallbladder or gynecologic surgery. If you are generally healthy and having one of these specific surgeries, you may be a good fit.
Yinchuan, NingxiaAges 18–70 - NCT07195045Recruiting
Thai PainPREDICT validation study for diabetes nerve pain
This study tests a tool (PainPREDICT) to predict nerve pain in people with diabetes. It aims to identify those at risk so treatment can start early.
Pathum Wan, BangkokAges 18 years+ - NCT07200544RecruitingPhase 4
Meloxicam for skin cancer surgery pain
This study tests if meloxicam, an anti-inflammatory painkiller, helps control pain after Mohs surgery for skin cancer. It aims to reduce the need for stronger opioid pain medicines.
Oklahoma City, OklahomaAges 18–110 - NCT07203040Enrolling by invitation
Ultrasound therapy for neck pain relief and muscle stiffness
This trial tests if a gentle ultrasound treatment can reduce neck pain and stiffness. It may be an option if you have ongoing neck pain and haven't had neck procedures recently.
ErzurumAges 18–50 - NCT07194967Enrolling by invitation
Virtual Reality for Pain Relief During Labor
This trial tests whether using virtual reality can help reduce pain and anxiety during labor. If you are having a low-risk pregnancy and plan a vaginal delivery, you may be able to use a VR headset during contractions to distract from pain.
Ben ArousAges 18–45 - NCT07197710Recruiting
Imagined acupuncture for pain after spine surgery
This trial tests if imagining acupuncture, guided by a video, can help reduce pain after spinal surgery. It is for adults having their first spine surgery on one or two bones.
Boston, MassachusettsAges 18 years+ - NCT07197879Recruiting
Does dynamic sitting prevent pain in office workers?
This study tests if a special swivel mechanism for office chairs can reduce or prevent back pain in people who sit a lot at work. It is for office workers who already develop pain during prolonged sitting.
Linz, Upper AustriaAges 18–65 - NCT07196787Recruiting
Exercise program for people starting isotretinoin
This trial tests whether a guided exercise program helps people taking isotretinoin—a strong acne medication—manage side effects and feel better. If you're starting isotretinoin for the first time and are not currently a regular exerciser, you may be able to join.
UşakAges 18–35
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,578 recruiting pain medicine studies from the U.S. registry right now, out of 6,493 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.