Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,578 recruiting studies in this area right now.
By phase
- Not applicable2,954
- Phase 4240
- Phase 2129
- Phase 3103
- Phase 193
- Phase 2/Phase 337
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University84
- Cairo University59
- Beijing Tiantan Hospital34
- Tanta University33
- Ain Shams University28
- Foundation University Islamabad28
- Mayo Clinic25
- VA Office of Research and Development23
- Hacettepe University22
- Stanford University21
Where studies are running
- California151
- New York79
- Massachusetts65
- Florida64
- Texas50
- North Carolina41
- Illinois40
- Maryland39
- Ohio39
- Minnesota37
Recruiting studies3,578 total
- NCT06921174RecruitingPhase 2
Pelvic pain relief after childbirth: massage vs device
This study compares two non-surgical therapies for postpartum perineal pain: traditional perineal massage versus a small silicone device used inside the vagina. If you have persistent pain after a vaginal birth and have not tried other treatments yet, this trial may help you find relief.
Murcia, MurciaAges 18 years+ - NCT06774274RecruitingPhase 4
Ketamine for pain after major orthopedic surgery: drip vs. pump
This study tests two ways of giving a medicine called ketamine to control pain after major bone or joint surgery. One method is a steady infusion (drip) through a vein, and the other is a patient-controlled pump (PCA) that lets you press a button for more medicine when you need it.
Medellín, AntioquiaAges 18 years+ - NCT06888804Recruiting
Nerve block for chronic heel fracture pain
This study tests a non-surgical treatment (pulsed radiofrequency, or PRF) applied to a nerve in the ankle to see if it can reduce long-term pain after a heel bone (calcaneus) fracture. It may be an option if you have had pain for more than 3 months and other treatments haven't worked.
AnkaraAges 18–80 - NCT07205614Recruiting
Good Pain Consultation for Endometriosis
This trial tests a new way to manage pain from endometriosis. It's a 'good pain consultation' designed to help women who have endometriosis and speak Norwegian.
Kristiansand, AgderAges 16–50 - NCT07209995Enrolling by invitation
Ultrasound-guided arm block for obese patients
This trial compares two types of ultrasound-guided nerve blocks for obese patients having surgery on or below the elbow. The goal is to find which approach works best for this group.
ZagazigAges 21–45 - NCT07209514Enrolling by invitation
Testing a spinal cord stimulator for diabetic nerve pain in the legs
This trial is studying a device called the Medtronic Inceptiv™ Closed-Loop DTM Spinal Cord Stimulator to see if it can help reduce pain from diabetic peripheral neuropathy (nerve damage caused by diabetes) in the lower legs. It is for people whose pain has lasted at least 6 months and hasn't been helped by other treatments.
Grand Island, NebraskaAges 19 years+ - NCT06347991Recruiting
Chiropractic self-care app study for back pain in Alberta
This study tests an app called SelfBack that helps chiropractic patients manage their own long-term low back pain. You will use your smartphone to receive personalized exercises and tips. It may help you take control of your back pain between chiropractic visits.
Edmonton, AlbertaAges 18 years+ - NCT06927531Recruiting
Pilates ball and massage for reducing labor pain
This study tests whether using a Pilates ball and sacral massage during labor can help reduce pain, shorten delivery time, and improve your birth experience. It is for first-time mothers with a full-term, low-risk pregnancy.
Şehitkamil, Gazi̇antepAges 18–35 - NCT06929000Recruiting
Testing an adjustable headrest for painless abortion in overweight patients
This study tests whether a special adjustable headrest can help make painless abortion surgery safer and more comfortable for people who are overweight or obese. You may be able to join if you are planning this procedure, have a BMI over 24, and are otherwise healthy enough for anesthesia.
Wuhan, HubeiAges 20–50 - NCT07208799RecruitingPhase 2
Steroid comparison for jaw fracture recovery
This trial compares two steroid medicines (dexamethasone and methylprednisolone) to see which one better reduces swelling, pain, and other symptoms after surgery for a broken lower jaw near the chin. It could help you recover faster and with less discomfort.
Multan, Punjab ProvinceAges 18–40 - NCT07211256Recruiting
Home brain stimulation for chronic pain
This trial tests if a gentle, home-use electrical brain stimulation device (tDCS) can help people with long-lasting pain that hasn't responded well to other treatments. If you have had pain for at least 6 months and a previous brain stimulation helped only briefly, this study may offer a new option.
Boulogne-Billancourt, Hauts de SeineAges 18–80 - NCT07204197Enrolling by invitation
Virtual Reality Physical Therapy After Lumbar Disc Surgery
This study tests whether using virtual reality (VR) during physical therapy after lumbar disc surgery helps you recover better in the first few days. You'll do standard exercises with or without VR games to see if it improves your movement and pain.
Ankara, AnkaraAges 18–65 - NCT07209566Recruiting
Muscles, nerves, and period pain in women
This study looks at how your muscles and nervous system relate to period pain. It compares women with and without painful periods to understand why some have more pain.
Azusa, CaliforniaAges 18–35 - NCT07205991Recruiting
Ways to stick with a back-pain mobile app
This trial tests strategies to help people with chronic low back pain use a mobile health app consistently. If you have ongoing back pain and participated in the NOTUS trial, this study might show you better ways to stay engaged with the app.
Sydney, New South WalesAges 18 years+ - NCT07210164Recruiting
Pre-surgery wellness program for gynecologic cancer surgery
This trial tests whether a pre-surgery wellness program (pre-habilitation) within an enhanced recovery protocol helps women recover better after surgery for endometrial, ovarian, or cervical cancer. It is designed for women who are having open abdominal surgery (laparotomy).
ThessalonikiAges 18–85 - NCT07209345Recruiting
Scalp pain relief after brain surgery
This trial tests whether numbing the scalp before brain surgery can reduce pain afterward. You would receive a painkiller injection in your scalp before your surgery begins.
BeijingAges 18–64 - NCT07207174Recruiting
Mindfulness vs CBT for chronic pain relief
This study compares two non-drug treatments—mindfulness training and cognitive-behavioral therapy—to see which helps adults with chronic pain better. Both aim to reduce pain and improve quality of life.
Tallahassee, FloridaAges 18 years+ - NCT07211308Recruiting
A study of spinal cord stimulation for chronic leg pain
This trial tests a type of spinal cord stimulation (DTM SCS) for people with chronic leg or foot pain caused by nerve damage (PSPS-T2). It aims to see if this treatment can safely reduce pain and improve daily life.
BrusselsAges Any age - NCT07211464Recruiting
ACT plus exercise for older adults with chronic low back pain
This study tests whether combining acceptance and commitment therapy (ACT) with exercise helps older adults manage ongoing low back pain. If you've had pain for at least 3 months and it's been bothering you, this approach might teach you new ways to cope and move better.
Hong KongAges 60 years+ - NCT07210203Recruiting
Nerve gliding for pain, balance, and quality of life in diabetic nerve damage
This study tests whether adding nerve gliding exercises (neural mobilization) to usual care can reduce pain, improve balance, and enhance quality of life for people with diabetic peripheral neuropathy. It may help if you have mild to moderate nerve pain and are between 50 and 75 years old.
IslamabadAges 50–75 - NCT07209280Enrolling by invitation
New screw system for pelvic fracture repair
This trial tests a newer type of screw to fix certain pelvic fractures. It aims to see if it works better than the standard screw for helping bones heal and for you to get back on your feet.
Salt Lake City, UtahAges 18–80 - NCT07203859Recruiting
Nerve block for pain after kidney stone surgery
This study tests a nerve block (called Quadro Iliac Plane Block) given during kidney stone surgery to see if it helps control pain after the procedure. If you are having this type of surgery and are generally healthy, you may be able to join.
Sivas, SivasAges 18–65 - NCT07206797Recruiting
Ultrasound to measure muscle activity from spinal cord stimulation
This study uses ultrasound to see how muscles respond to two types of electrical stimulation (spinal cord and functional electrical stimulation). It may help researchers better understand how to treat muscle weakness or paralysis.
Raleigh, North CarolinaAges 18–60 - NCT07208357Recruiting
Pregabalin with toludesvenlafaxine for fibromyalgia pain
This study tests a combination of two medications (pregabalin and toludesvenlafaxine) to see if it is safe and effective for people with fibromyalgia whose pain has not improved with non-drug treatments and who have not yet tried standard medications for this condition.
BeijingAges 18 years+
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,578 recruiting pain medicine studies from the U.S. registry right now, out of 6,493 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.