Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,578 recruiting studies in this area right now.
By phase
- Not applicable2,954
- Phase 4240
- Phase 2129
- Phase 3103
- Phase 193
- Phase 2/Phase 337
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University84
- Cairo University59
- Beijing Tiantan Hospital34
- Tanta University33
- Ain Shams University28
- Foundation University Islamabad28
- Mayo Clinic25
- VA Office of Research and Development23
- Hacettepe University22
- Stanford University21
Where studies are running
- California151
- New York79
- Massachusetts65
- Florida64
- Texas50
- North Carolina41
- Illinois40
- Maryland39
- Ohio39
- Minnesota37
Recruiting studies3,578 total
- NCT07075055Recruiting
New bioceramic medication for infected front teeth
This trial tests a new bioceramic medication placed inside the root canal of infected front teeth to see if it improves healing. It is for adults with mature front teeth and an infection around the root tip, who are otherwise healthy.
MinyaAges 18–40 - NCT07074730Recruiting
Anesthesia types for urethral surgery
This trial compares general anesthesia versus spinal anesthesia with local numbing medicine for penis skin graft surgery. It aims to see which method works better for pain control and recovery.
Tanta, El-GharbiaAges 21 years+ - NCT07070401Recruiting
VR for kidney stone pain in the ER
This trial tests whether using a virtual reality headset can help reduce pain in people coming to the emergency room with kidney stone pain. If you have had kidney stones before and are in significant pain, this might be a way to feel better without relying only on medication.
Toms River, New JerseyAges 18 years+ - NCT06936904Recruiting
Speed of numbing medicine in a nerve block for lung nodule localization
This trial tests if the injection speed affects how well a numbing medicine spreads during a specific type of nerve block used for CT-guided lung nodule localization. It may help reduce discomfort during the procedure.
Nanjing, JiangsuAges 18–80 - NCT06984874Recruiting
Nerve block for kids having chest surgery
This study tests a nerve block injection in the back to reduce pain in children aged 6–16 having a specific type of chest surgery (thoracoscopic sympathectomy). It may help them wake up more comfortable and need less pain medicine.
Shibīn al Kawm, MenoufiaAges 6–16 - NCT06985849Recruiting
Gentle exercise for chronic low back pain
This study compares two gentle exercise programs (Feldenkrais and Otago) to see which one helps people with chronic low back pain and balance problems feel better and move more easily. It focuses on adults who have had pain for at least 3 months and have some trouble with balance.
LahoreAges 18–65 - NCT05152264Recruiting
TENS device study for endometriosis-related chronic pain
This study tests whether a skin-applied electrical nerve pain-relief device (TENS) can help with long-lasting pain from endometriosis. It mainly looks at people who have confirmed endometriosis and are on stable hormone treatment.
GothenburgAges 18–100 - NCT07057128Recruiting
Do nerve issues occur in shoulder pain syndrome?
This study looks at whether nerve-related symptoms are common in people with subacromial pain syndrome (a type of shoulder pain). You may qualify if you have shoulder pain that has lasted at least 3 months, with moderate to severe pain in the past week, and if you haven't had shoulder surgery or certain other shoulder problems.
Izmir, İzmirAges 19 years+ - NCT07058636Recruiting
Nerve block plus trigger point shots for neck pain relief
This study tests if adding a nerve block to standard trigger point injections provides better relief for people with chronic neck pain caused by myofascial pain syndrome.
AnkaraAges 18–65 - NCT07063394Recruiting
Virtual reality to reduce opioid use after heart or lung surgery
This trial tests if using virtual reality after heart or chest surgery can help reduce the amount of strong painkillers (opioids) patients need. It may offer a non-drug way to manage pain and speed up recovery.
São Paulo, São PauloAges 16–40 - NCT07059754Recruiting
Cooling treatment for chronic eye surface pain
This trial tests a cooling treatment (EyeCool) for people with long-term pain on the eye's surface. It looks at how the treatment affects the eye's surface structure and inflammation after standard care hasn't worked well enough.
Melbourne, VictoriaAges 22–90 - NCT07061769Enrolling by invitation
Using a gentle head device to help with nerve pain from chemo
This trial tests a low-intensity cranial PEMF device to see if it can reduce nerve pain caused by chemotherapy. Participants use the device at home and receive text messages to track their symptoms.
Newport Beach, CaliforniaAges 18–60 - NCT07062146Recruiting
Reiki for pain after back fusion surgery
This study tests whether Reiki (a gentle hands-on energy therapy) can help reduce pain after lower back fusion surgery. It aims to see if adding Reiki to standard care improves recovery.
ParisAges 18–75 - NCT07061067Recruiting
How symptom duration affects lower back surgery results
This study looks at how long your symptoms have lasted before lower back surgery and whether that affects your recovery. If you're planning a lumbar spine operation and have symptoms like back or leg pain, this trial may help doctors understand the best timing for surgery.
Kafr ash Shaykh, KafrelsheikhAges 18 years+ - NCT07056140Recruiting
Simulation training for epidural pain relief placement
This trial tests if simulation-based training helps anesthesia residents learn to place epidural catheters for pain relief. It may be right for you if you are a resident with little experience placing epidurals.
PadovaAges 18 years+ - NCT07061782Recruiting
Neck stretching techniques for IT workers with upper cross syndrome
This trial compares two types of stretching exercises to see which one helps reduce neck and shoulder pain in IT professionals with upper cross syndrome. It may help you move better and feel less pain from long hours at the computer.
IslamabadAges 20–40 - NCT07057557Recruiting
Aloe vera vs paraffin dressing for skin graft pain
This trial compares aloe vera dressing with paraffin tulle dressing to see which one reduces pain better at the area where a skin graft was taken. If you need a skin graft and are not allergic to either dressing, this study may help find a gentler way to manage your pain.
Lahore, Punjab ProvinceAges 18–60 - NCT07060495RecruitingPhase 3
RADA16 gel for pain after adult tonsillectomy
This trial tests a new gel (RADA16) placed on the tonsil area after surgery to see if it helps reduce pain and speed healing. It is for adults having a standard tonsillectomy.
Livingston, New JerseyAges 18 years+ - NCT07055971Enrolling by invitation
Pain education and brain training for fibromyalgia
This trial tests whether a program that teaches you about pain and helps your brain control pain better can improve fibromyalgia symptoms. It also looks at how emotions play a role.
Granada, AndalusiaAges 18 years+ - NCT07061847RecruitingPhase 2
Lidocaine infusion for severe chronic migraines
This trial tests if a lidocaine infusion into an artery in the head can reduce severe chronic daily headaches. It is for people who have tried multiple treatments without enough relief.
Great Neck, New YorkAges 18–75 - NCT07062497RecruitingPhase 2/Phase 3
Clonidine in nerve block for umbilical hernia repair
This trial tests if adding clonidine to a numbing injection (nerve block) improves pain control after outpatient umbilical hernia repair. It aims to reduce the need for pain medicines and enhance recovery.
Rio de Janeiro, Rio de JaneiroAges 18–65 - NCT07059546Recruiting
Studying sensitivity to adrenomedullin in chronic post-traumatic headache
This trial tests whether people with long-term headache after a mild head injury have an abnormal reaction to a substance called adrenomedullin, which may play a role in causing headaches. You will receive adrenomedullin and a placebo in separate sessions to see how your headache responds.
Glostrup MunicipalityAges 18–65 - NCT07055178Recruiting
Virtual reality for pain and anxiety during vasectomy
This study tests if using a virtual reality headset during a vasectomy can help lower pain and anxiety. It compares VR with standard care to see which works better for patients.
Winnipeg, ManitobaAges 18 years+ - NCT07062757Enrolling by invitation
Massage and melatonin for jaw surgery recovery
This study tests whether combining gentle lymphatic drainage massage with melatonin can reduce pain and swelling after jaw surgery. If you are scheduled for jaw surgery for the first time and are otherwise healthy, you may be able to join.
Istanbul, FatihAges 16–55
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,578 recruiting pain medicine studies from the U.S. registry right now, out of 6,493 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.