Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,578 recruiting studies in this area right now.
By phase
- Not applicable2,954
- Phase 4240
- Phase 2129
- Phase 3103
- Phase 193
- Phase 2/Phase 337
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University84
- Cairo University59
- Beijing Tiantan Hospital34
- Tanta University33
- Ain Shams University28
- Foundation University Islamabad28
- Mayo Clinic25
- VA Office of Research and Development23
- Hacettepe University22
- Stanford University21
Where studies are running
- California151
- New York79
- Massachusetts65
- Florida64
- Texas50
- North Carolina41
- Illinois40
- Maryland39
- Ohio39
- Minnesota37
Recruiting studies3,578 total
- NCT07057557Recruiting
Aloe vera vs paraffin dressing for skin graft pain
This trial compares aloe vera dressing with paraffin tulle dressing to see which one reduces pain better at the area where a skin graft was taken. If you need a skin graft and are not allergic to either dressing, this study may help find a gentler way to manage your pain.
Lahore, Punjab ProvinceAges 18–60 - NCT07063602Recruiting
Comparing nerve block methods for pain after lung surgery
This study compares two ways of giving a paravertebral nerve block (an injection near the spine to numb the chest) to control pain after a type of lung surgery called VATS. It aims to find the best approach for reducing pain and the need for stronger pain medicines.
Montreal, QuebecAges 18 years+ - NCT07064200Recruiting
Timing of TAP blocks for abdominal surgery
This study compares two different ways to give a numbing medicine (TAP block) before abdominal surgery to see which one works better for pain control. If you are scheduled for elective abdominal surgery, joining may help doctors find the best way to manage your pain.
New York, New YorkAges 18–65 - NCT07056244Recruiting
Comparing two pain medicines for children’s hernia surgery
This study tests whether adding dexmedetomidine or dexamethasone to the standard numbing medicine (bupivacaine) provides better pain relief for children getting hernia surgery. The medicine is given through a shot in the lower back (caudal epidural block) to help keep your child comfortable during and after the operation.
SohagAges 2–6 - NCT07064434Recruiting
Nerve block for safer blood pressure control during hip replacement
This trial tests a type of nerve block (sacral canal block) to help manage blood pressure during hip replacement surgery. It aims to see if it can safely lower blood pressure on purpose, which may reduce bleeding and improve recovery.
Yinchuan, NingxiaAges 45 years+ - NCT07058220Recruiting
Neck training for neck pain relief
This trial tests whether special neck position-sense exercises can help people with general neck pain feel better. It may be a good option if you have neck pain without a specific injury.
GizaAges 25–45 - NCT07063147Recruiting
Heart ultrasound for stable chest pain management
This study uses a heart ultrasound (TTE) to help doctors better manage stable chest pain. If you have chest pain that may be from a blocked artery but haven't had a heart attack or heart procedures before, this trial could help improve your care.
TianjinAges 18 years+ - NCT07062146Recruiting
Reiki for pain after back fusion surgery
This study tests whether Reiki (a gentle hands-on energy therapy) can help reduce pain after lower back fusion surgery. It aims to see if adding Reiki to standard care improves recovery.
ParisAges 18–75 - NCT07056140Recruiting
Simulation training for epidural pain relief placement
This trial tests if simulation-based training helps anesthesia residents learn to place epidural catheters for pain relief. It may be right for you if you are a resident with little experience placing epidurals.
PadovaAges 18 years+ - NCT07055178Recruiting
Virtual reality for pain and anxiety during vasectomy
This study tests if using a virtual reality headset during a vasectomy can help lower pain and anxiety. It compares VR with standard care to see which works better for patients.
Winnipeg, ManitobaAges 18 years+ - NCT05841732Recruiting
Behavior program with exercise to prevent low back pain returning
This trial tests a phone-based behavior change exercise program to help stop low back pain from coming back. It is for people who recently recovered from a recent low back pain episode and can safely do exercises.
Setúbal, Setúbal DistrictAges 18–65 - NCT06502457Recruiting
Virtual reality hypnosis for labor pain
This study tests whether using a virtual reality hypnosis program can help manage pain during early labor in women with low-risk pregnancies. If you are in the beginning stages of labor and want a non-drug option for comfort, this might be for you.
AmiensAges 18 years+ - NCT06955117Recruiting
McKenzie vs manual therapy for low back pain
This study compares two physical therapy methods to see which works better for low back pain that has lasted more than 4 weeks. It could help you find a more effective treatment without surgery or strong medication.
Malakand, KPKAges 35–45 - NCT07048808RecruitingPhase 2
Gene therapy for chronic chest pain
This trial tests a new gene therapy (XC001) delivered through a thin tube into your heart's blood vessels. It aims to grow new blood vessels to relieve chest pain in people with chronic angina who have no other treatment options.
Birmingham, AlabamaAges 18–85 - NCT07044713Recruiting
Fun activities for kids during blood tests
This trial tests if hand puppets, coloring books, or watching images can help children ages 3-6 feel less scared during blood draws. It's for healthy kids who need blood taken once.
Kilis, CentralAges 3–6 - NCT07044869Recruiting
Comparing two hand therapies for piriformis syndrome in women
This study compares two gentle hands-on treatments – a 'facilitated positional release' technique and a 'manual myofascial release' technique – to see which better relieves pain from piriformis syndrome in women.
IslamabadAges 25–50 - NCT07046572Recruiting
Pain relief for IUD insertion or endometrial biopsy
This trial tests if a pain-relief medication called methoxyflurane can help women who haven't had children before feel less pain during IUD insertion or a uterine biopsy. If you're getting one of these procedures and are not currently breastfeeding or using strong painkillers, this study might be for you.
Toronto, OntarioAges 18–65 - NCT07054775RecruitingPhase 4
Comparing itching after two doses of spinal morphine in C-section
This study compares two low doses of morphine given during spinal anesthesia for planned cesarean sections, to see which causes less itching. It aims to find a safer way to manage pain after birth.
Khon KaenAges 18–45 - NCT07048769RecruitingPhase 4
Pain relief shot for saline ultrasound of the uterus
This trial tests if a numbing injection in the cervix reduces pain during a saline ultrasound that checks the uterus and fallopian tubes. It might help make the procedure more comfortable for you.
Hartsdale, New YorkAges 18–50 - NCT07053982Recruiting
New scan to find endometriosis spots
This trial tests a new type of PET/CT scan that uses a special tracer to find endometriosis lesions. It may help surgeons see exactly where the disease is, which could lead to more complete treatment.
ToulouseAges 18 years+ - NCT07051577Recruiting
Brain-Based Training for Young Archers
This study tests a special brain-based training program for young archers aged 15–18. The goal is to see if these exercises can improve your shooting accuracy and how your muscles work.
Istanbul, IstanbulAges 15–18 - NCT07051265Enrolling by invitation
Pain relief for head and neck cancer patients using TENS or acupressure
This study compares two non-drug methods—TENS (a mild electrical device) and acupressure (gentle finger pressure on specific points)—to help manage pain in people with head and neck cancer. If you have cancer-related pain and need medication, you may be able to join.
Kaohsiung CityAges 20–100 - NCT07050212Recruiting
Sedation study for children having tonsil surgery
This study tests three different medicines to help young children relax before surgery to remove their tonsils and adenoids. It aims to find which medicine works best and is safest for kids ages 2 to 5.
Wuhan, HubeiAges 2–5 - NCT07046143Enrolling by invitation
Spinal cord stimulation for nerve pain in the lower back
This trial tests a non-invasive treatment that uses mild electrical stimulation on the skin over the spine to help relieve nerve-related pain in the lower back. It may be an option for people with chronic nerve pain, with or without pain spreading down the leg.
Nanchang, JiangxiAges 18–80
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,578 recruiting pain medicine studies from the U.S. registry right now, out of 6,493 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.