Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,611 recruiting studies in this area right now.
By phase
- Not applicable3,768
- Phase 2217
- Phase 4200
- Phase 1182
- Phase 3139
- Phase 1/Phase 271
- Phase 2/Phase 334
Top conditions
- Knee Osteoarthritis172
- Rheumatoid Arthritis132
- Fibromyalgia105
- Osteoporosis82
- Osteoarthritis71
- Rheumatoid Arthritis (RA)68
- Osteoarthritis, Knee64
- Shoulder Pain48
- Hip Osteoarthritis43
- Psoriatic Arthritis40
- Degenerative Disc Disease39
- Chronic Pain38
- Total Knee Arthroplasty38
- Duchenne Muscular Dystrophy37
- Systemic Lupus Erythematosus37
- Musculoskeletal Pain35
- Osteoarthritis (OA) of the Knee32
- Pain32
Leading sponsors
- Riphah International University85
- Istituto Ortopedico Rizzoli69
- Cairo University65
- Assistance Publique - Hôpitaux de Paris36
- Foundation University Islamabad31
- Mayo Clinic28
- Massachusetts General Hospital25
- National Taiwan University Hospital25
- Hacettepe University23
- Tanta University22
Where studies are running
- California207
- New York87
- Florida82
- Maryland76
- Arizona72
- Massachusetts71
- Texas67
- Alabama59
- Illinois51
- Pennsylvania48
Recruiting studies4,611 total
- NCT06557369Recruiting
New light therapy for intermediate age-related macular degeneration
This trial tests a new light-based treatment for intermediate age-related macular degeneration (AMD), a common eye condition that can lead to vision loss. The goal is to see if it is safe and helps slow down the disease.
BergamoAges 50 years+ - NCT07638319RecruitingEarly Phase 1
Bone filler to preserve jawbone after tooth extraction
This early-stage trial tests a bone filler material (Neocement Inject P) placed in the socket after tooth removal to help preserve jawbone volume. This may help if you need a dental implant later.
Caparica, Monte Da CaparicaAges 18 years+ - NCT07642882Recruiting
Brain Stimulation for Fibromyalgia Pain Relief
This study tests whether a non-invasive brain stimulation treatment (rTMS) can reduce chronic pain in fibromyalgia patients. The treatment uses magnetic pulses to stimulate specific areas of the brain and may help relieve widespread pain.
Boulogne-Billancourt, Île-de-France RegionAges 18–80 - NCT07639177RecruitingPhase 2
Fecal Microbiota Transplant for Hard-to-Treat Rheumatoid Arthritis
This trial tests whether transferring healthy gut bacteria from a donor to patients with rheumatoid arthritis that hasn't improved on standard medications can reduce joint pain and swelling. The goal is to see if rebalancing the gut microbiome (the community of bacteria in your intestines) helps control inflammation.
Beijing, Beijing MunicipalityAges 18–65 - NCT07639060Recruiting
Pain Relief Study Using Freezing Nerve Treatment
This study watches how well a freezing procedure works for chronic pain over 6 to 12 months. Your doctor thinks this procedure could help your pain, and the study simply tracks your recovery through questionnaires to help doctors understand if it works.
Old Saybrook, ConnecticutAges 18 years+ - NCT07642713Recruiting
Manual therapy with or without spine manipulation for pelvic pain
This study tests whether manual therapy (hands-on treatment) works better alone or combined with spine manipulation for women with pain near the lower back and pelvis. If you have this type of pain, the trial may help you access treatment while researchers learn what works best.
Lahore, Punjab ProvinceAges 25–40 - NCT07645859Recruiting
High-Intensity vs. Moderate Exercise for Chronic Lower Back Pain
This trial compares two types of exercise programs—one with short, intense bursts of activity and one with steady, moderate activity—to see which works better for people with long-lasting lower back pain that has no clear medical cause. You would participate in supervised exercise sessions over several weeks.
KarachiAges 20–48 - NCT07641621Recruiting
Chiropractic Ankle Treatment and Jump Performance Study
This study tests whether chiropractic ankle manipulation improves how high and powerfully you can jump. Researchers will work with recreationally active adults to see if this treatment affects athletic performance.
Seneca Falls, New YorkAges 18–35 - NCT07642622Recruiting
Physical Activity Tracking With Wearable Technology for Spine Arthritis
This study tests whether wearing a Fitbit activity tracker and using a Google Health app can help people with axial spondyloarthritis (a type of spine arthritis) become more physically active. The goal is to see if this technology-based approach motivates people to exercise more, which may help reduce pain and improve their condition.
Seattle, WashingtonAges 18 years+ - NCT07640620Recruiting
How nerve sensitivity relates to heel pain
This study looks at whether people with plantar fasciitis (painful heel condition) have heightened nerve sensitivity, and how this connects to their symptoms. Researchers will compare your pain patterns and nerve responses to those of healthy volunteers to better understand what drives heel pain.
IstanbulAges 18–65 - NCT07644624Recruiting
Sling vs. Dynamic Support After Shoulder Stabilization Surgery
This trial compares two different ways to support your shoulder after arthroscopic surgery to fix anterior shoulder instability (a condition where your shoulder joint slips forward). Researchers want to see which support method—a traditional sling or a dynamic stabilizer—helps you recover better with less pain and better function.
L'Hospitalet de Llobregat, CataloniaAges 18 years+ - NCT07644078Recruiting
Understanding Cavovarus Foot Deformity in Nerve Disorders
This study examines how nerve disorders like Charcot-Marie-Tooth disease cause a specific type of foot deformity (cavovarus feet, where the foot has a high arch and turned-in appearance). Researchers will either examine you directly or review your existing medical records to better understand this condition and how it affects people.
StanmoreAges 18 years+ - NCT07645794Enrolling by invitation
MRI Scans to Detect Bone and Muscle Loss in Kidney Disease
This study tests a new MRI imaging method to detect bone loss (osteoporosis) and muscle loss (sarcopenia) in people with chronic kidney disease. The scan may help doctors catch these problems earlier and manage kidney disease better.
Beijing, Beijing MunicipalityAges 18–80 - NCT07640126Recruiting
Acupuncture for cold-sensitive neck pain
This trial tests whether a specific type of acupuncture (three-needle Dazhui plus electroacupuncture) can reduce pain and improve function in people with neck pain caused by cervical spondylosis, especially when the pain is worse in cold weather. It combines a modern diagnosis with traditional Chinese medicine ideas to see if this approach helps more than standard care.
Ho Chi Minh CityAges 3 weeks+ - NCT04117685Recruiting
Global hip dysplasia registry for young children
This trial is a worldwide registry that collects information from children with hip dysplasia or who are at higher risk. It helps researchers understand who is affected and how hip evaluations are done, which can improve future care.
Vancouver, British ColumbiaAges 1 minute–10 years - NCT05824845Recruiting
Join a study collecting information for hip or knee replacement care
This study asks people in the UK who are getting their first hip or knee replacement to answer questionnaires and let researchers use linked health data. The goal is to improve understanding of outcomes and help set up future studies for better care.
AshingtonAges 18 years+ - NCT06523426Recruiting
Outpatient spine surgery for adults over 75
This trial tests a minimally invasive spine surgery (endoscopic decompression) done as an outpatient procedure in people 75 and older. It aims to see if this approach is safe and effective for treating a single-level lumbar spine problem.
BordeauxAges 75 years+ - NCT07637162Enrolling by invitationPhase 3
Safety study of AXS-14 for fibromyalgia
This study continues to monitor the safety of an investigational drug called AXS-14 in people with fibromyalgia who previously participated in another AXS-14 trial. Researchers want to make sure the treatment remains safe over time.
Little Rock, ArkansasAges 18 years+ - NCT07637682Recruiting
Percutaneous Neurostimulation for Knee Osteoarthritis Pain
This trial tests a minimally invasive nerve-stimulation treatment for moderate to severe knee osteoarthritis pain in adults who have not found relief with standard treatments. The procedure uses small needles to deliver electrical stimulation near nerves to reduce pain.
TantaAges 18 years+ - NCT07632846RecruitingPhase 2
Roflumilast as add-on treatment for active rheumatoid arthritis
This study tests whether adding roflumilast, a new medication, to your current rheumatoid arthritis treatment can help reduce joint inflammation and improve your symptoms. You would take it alongside methotrexate, a common RA medication you may already be using.
Al MansurahAges 18–60 - NCT07633821Recruiting
3D-Printed Hand Brace for Daily Living Support
This trial tests a custom 3D-printed hand brace (orthosis) designed to help you use your hand better in everyday activities. You would wear it regularly to see if it improves your ability to do daily tasks like eating, dressing, or writing.
Amsterdam, North HollandAges 18 years+ - NCT07636148Recruiting
Registry of minimally invasive cancer treatment with advanced imaging
This study collects information from patients undergoing minimally invasive procedures to treat solid tumors (cancers) using advanced CT imaging guidance. Researchers want to understand how well this imaging technique helps doctors perform these procedures safely and effectively.
Lyon, Auvergne-Rhône-AlpesAges 18 years+ - NCT07634276Recruiting
Custom surgical guides for jaw realignment surgery
This trial tests personalized surgical guides and implants to help surgeons precisely reposition the upper and lower jaw in patients with facial asymmetry or misalignment. The goal is to improve surgical accuracy and final bite alignment.
BeijingAges 18–40 - NCT07634224Recruiting
Energy Transfer Therapy for Tennis Elbow Pain
This study tests whether a special energy-based therapy (called capacitive and resistive energy transfer) can reduce pain and improve function in people with tennis elbow—a common overuse injury of the outer elbow. You'll receive this non-invasive treatment and have your progress tracked over time.
Gaziantep, GaziantepAges 18–65
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,611 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,492 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.