Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,611 recruiting studies in this area right now.
By phase
- Not applicable3,768
- Phase 2217
- Phase 4200
- Phase 1182
- Phase 3139
- Phase 1/Phase 271
- Phase 2/Phase 334
Top conditions
- Knee Osteoarthritis172
- Rheumatoid Arthritis132
- Fibromyalgia105
- Osteoporosis82
- Osteoarthritis71
- Rheumatoid Arthritis (RA)68
- Osteoarthritis, Knee64
- Shoulder Pain48
- Hip Osteoarthritis43
- Psoriatic Arthritis40
- Degenerative Disc Disease39
- Chronic Pain38
- Total Knee Arthroplasty38
- Duchenne Muscular Dystrophy37
- Systemic Lupus Erythematosus37
- Musculoskeletal Pain35
- Osteoarthritis (OA) of the Knee32
- Pain32
Leading sponsors
- Riphah International University85
- Istituto Ortopedico Rizzoli69
- Cairo University65
- Assistance Publique - Hôpitaux de Paris36
- Foundation University Islamabad31
- Mayo Clinic28
- Massachusetts General Hospital25
- National Taiwan University Hospital25
- Hacettepe University23
- Tanta University22
Where studies are running
- California207
- New York87
- Florida82
- Maryland76
- Arizona72
- Massachusetts71
- Texas67
- Alabama59
- Illinois51
- Pennsylvania48
Recruiting studies4,611 total
- NCT07632846RecruitingPhase 2
Roflumilast as add-on treatment for active rheumatoid arthritis
This study tests whether adding roflumilast, a new medication, to your current rheumatoid arthritis treatment can help reduce joint inflammation and improve your symptoms. You would take it alongside methotrexate, a common RA medication you may already be using.
Al MansurahAges 18–60 - NCT07636148Recruiting
Registry of minimally invasive cancer treatment with advanced imaging
This study collects information from patients undergoing minimally invasive procedures to treat solid tumors (cancers) using advanced CT imaging guidance. Researchers want to understand how well this imaging technique helps doctors perform these procedures safely and effectively.
Lyon, Auvergne-Rhône-AlpesAges 18 years+ - NCT07634224Recruiting
Energy Transfer Therapy for Tennis Elbow Pain
This study tests whether a special energy-based therapy (called capacitive and resistive energy transfer) can reduce pain and improve function in people with tennis elbow—a common overuse injury of the outer elbow. You'll receive this non-invasive treatment and have your progress tracked over time.
Gaziantep, GaziantepAges 18–65 - NCT07633340Recruiting
Shock Wave Therapy Plus Rehab for Shoulder Blade Problems
This study compares two treatment approaches for scapular dyskinesis (abnormal shoulder blade movement): one group receives shock wave therapy along with standard exercises, while the other group does exercises alone. Researchers want to see if adding shock wave therapy helps improve shoulder blade function and reduces pain.
TantaAges 18 years+ - NCT07629674Recruiting
Video Therapy to Help Leg Movement Recovery After Stroke
This study tests whether watching specially designed videos can help improve leg strength and walking ability in people recovering from stroke. You'll receive this video therapy alongside your regular rehabilitation care.
Saint-EtienneAges 18–80 - NCT07637682Recruiting
Percutaneous Neurostimulation for Knee Osteoarthritis Pain
This trial tests a minimally invasive nerve-stimulation treatment for moderate to severe knee osteoarthritis pain in adults who have not found relief with standard treatments. The procedure uses small needles to deliver electrical stimulation near nerves to reduce pain.
TantaAges 18 years+ - NCT07630337Recruiting
Cryotherapy to reduce pain medication after knee replacement
This study tests whether applying cold therapy (cryotherapy) after knee replacement surgery helps patients need fewer opioid pain medications than standard care alone. If cryotherapy works, it could help you manage pain more safely after surgery.
Buenos Aires, Buenos AiresAges 18 years+ - NCT07634276Recruiting
Custom surgical guides for jaw realignment surgery
This trial tests personalized surgical guides and implants to help surgeons precisely reposition the upper and lower jaw in patients with facial asymmetry or misalignment. The goal is to improve surgical accuracy and final bite alignment.
BeijingAges 18–40 - NCT07633587Recruiting
Cancer Survival Study After Heart Inflammation from Immunotherapy
This research tracks outcomes for cancer patients who developed heart inflammation (myocarditis) while receiving immune checkpoint inhibitor therapy. By studying survival patterns, researchers hope to better understand how to manage this serious side effect and improve care for future patients.
ParisAges Any age - NCT07636967Recruiting
Ankle Muscle Strength in Chronic Low Back Pain
This study measures the strength and function of ankle muscles in people with chronic low back pain lasting over 3 months. Understanding how ankle muscles work may help explain why some people develop long-term low back pain.
Tanta, Gharbia GovernorateAges 20–25 - NCT07630896RecruitingPhase 4
Prednisone and blood sugar monitoring after knee or hip replacement
This study looks at how a common steroid medicine, prednisone, affects blood sugar after knee or hip replacement surgery. It aims to find the best way to manage blood sugar for a smoother recovery.
New York, New YorkAges 18 years+ - NCT07630389Recruiting
Remote monitoring for childhood myotonic dystrophy
This study uses video calls and online assessments to track how myotonic dystrophy (a muscle-weakening condition) affects children over time. Researchers will also look at genetic factors to better understand the disease and improve care.
Rochester, New YorkAges birth–17 years - NCT06222736Recruiting
Cervical core exercises for jaw joint pain relief
This study tests whether exercises for the neck and upper back can reduce pain and improve function in women with jaw joint problems caused by muscle pain. It could help if you have jaw pain related to tense or sore muscles.
Istanbul, AvcılarAges 18 years+ - NCT06694532RecruitingPhase 1/Phase 2
Arthrocentesis with hyaluronic acid for TMJ disorders
This trial tests two types of hyaluronic acid (high vs low molecular weight) given during a jaw joint procedure (arthrocentesis) to see which better relieves pain and improves jaw function in people with TMJ disorders.
AsyutAges 18–100 - NCT06097091Recruiting
Pain education for fibromyalgia patients
This trial tests if learning about how your brain and nerves process pain can help reduce fibromyalgia symptoms. You will attend sessions that teach you about the science of pain and how to manage it better.
TaipeiAges 18–64 - NCT06003101RecruitingPhase 3
Blood treatments for hip labrum tear surgery
This study tests whether adding platelet-rich plasma (a blood concentrate), platelet-poor plasma, or bone marrow concentrate during hip surgery helps people with a torn labrum recover better. If you need hip arthroscopy and haven't had prior hip surgery, you may be able to join.
Boston, MassachusettsAges 18 years+ - NCT07621068Recruiting
Hyperbaric Oxygen Therapy for Chronic Fatigue Syndrome
This study tests whether breathing pure oxygen in a pressurized chamber can reduce fatigue and improve symptoms in people with mild-to-moderate chronic fatigue syndrome (ME/CFS). The therapy may help your body recover better by increasing oxygen supply to affected tissues.
ZrifinAges 18 years+ - NCT07628218Recruiting
Video versus in-person exercise training for heel pain
This trial compares two ways to learn exercises for plantar fasciitis (heel pain caused by tissue strain): watching instructional videos on your own versus attending sessions with a doctor or trainer. The goal is to see which method helps reduce pain and improve walking more effectively.
BalıkesirAges 18–70 - NCT07621809RecruitingPhase 3
Ianalumab versus placebo for Sjögren's disease with high symptom burden
This study tests whether a new drug called ianalumab can reduce dry mouth and other symptoms in people with Sjögren's disease—a condition where the immune system attacks moisture-producing glands. Participants will receive either ianalumab or a placebo (inactive injection) over 52 weeks to see if the drug helps.
Peoria, ArizonaAges 18 years+ - NCT06697860Recruiting
Shockwave vs. massage for chronic heel pain
This study compares two treatments for chronic heel pain (plantar fasciitis): radial shockwave therapy and Graston technique (a special scraping massage). It aims to see which works better to reduce pain and improve function in adults aged 20–45 who have had symptoms for more than 3 months.
Lahore, Punjab ProvinceAges 5 months–10 months - NCT07625150Recruiting
PET/MRI Imaging Study of Kneecap Joint Osteoarthritis
This research study uses advanced imaging (PET and MRI scans) to better understand osteoarthritis in the front of the knee, where the kneecap meets the thighbone. You'll help researchers learn how to detect and track this condition earlier.
San Francisco, CaliforniaAges 18 years+ - NCT07627308Recruiting
Ultrasound vs Fluoroscopy for Nerve Injections in Back Pain
This trial compares two imaging methods—ultrasound and fluoroscopy (X-ray)—to guide nerve injections for leg pain caused by compressed nerves in the lower back. The goal is to see which method is safer and more effective at relieving your pain.
Tanta, Gharbia GovernorateAges 18–75 - NCT07624474Recruiting
Testing an elbow injury score for French-speaking children
This study is testing a French translation of a scoring system that measures how well children's elbows are working after injury. Researchers want to make sure this tool accurately reflects how kids actually function.
AmiensAges 4–17 - NCT07621679Recruiting
Walking Program to Prevent Falls and Fractures in Older Adults
This study tests whether a specialized walking and balance program helps people aged 70+ with weak bones reduce their risk of falls and fractures. The program is designed to improve strength, balance, and confidence in daily movement.
Montreal, QuebecAges 70 years+
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,611 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,492 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.