Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,420 recruiting studies in this area right now.
By phase
- Not applicable9,752
- Phase 2783
- Phase 1576
- Phase 3536
- Phase 4343
- Phase 1/Phase 2307
- Phase 2/Phase 3123
Top conditions
- Stroke844
- Parkinson Disease426
- Alzheimer Disease342
- Multiple Sclerosis341
- Dementia227
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea156
- Insomnia155
- Spinal Cord Injuries153
- Traumatic Brain Injury150
- Sarcopenia149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment130
- Migraine113
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California679
- Massachusetts300
- New York292
- Florida275
- Texas266
- Maryland246
- Arizona213
- Alabama210
- Illinois187
- Pennsylvania178
Recruiting studies12,418 total
- NCT06497595Recruiting
Lifestyle program to prevent muscle loss in older adults with diabetes on semaglutide
This trial tests whether a lifestyle program (diet and exercise) can help prevent muscle loss in people 65 and older with type 2 diabetes and obesity who are taking semaglutide. It may help you keep your strength and independence while losing weight.
Jerusalem, IsraelAges 65 years+ - NCT07716787Recruiting
Brain monitoring during breathing therapy in critically ill patients
This study looks at how a breathing machine setting (called PEEP) affects blood flow in the brain. If you or your loved one is in the ICU with a serious brain injury and is on a breathing machine, this trial could help doctors understand how to make breathing therapy safer for the brain.
Dongying, ShandongAges 18 years+ - NCT07716475Recruiting
Home gait training with a hip robot for stroke recovery
This trial tests a wearable hip robot to help people with stroke walk better at home. It may improve your gait and daily movement.
Yongin-si, Gyeonggi-doAges 19–80 - NCT07717333Recruiting
Sarcopenia signs after weight loss surgery
This study looks at muscle changes after bariatric (weight loss) surgery. It may help you understand how your muscles are affected and what you can do to stay strong.
Istanbul, KÜÇÜKÇEKMECEAges 18–65 - NCT02896335RecruitingPhase 2
Palbociclib and pembrolizumab for brain metastases
This study tests two drugs, palbociclib and pembrolizumab, for people whose solid tumors (like breast cancer or melanoma) have spread to the brain. The goal is to see if this combination can shrink or slow the growth of brain tumors that are progressing despite prior treatment.
Boston, MassachusettsAges 18 years+ - NCT07717281Recruiting
Studying nerve-muscle organoids for refractory myasthenia gravis
This study uses lab-grown mini muscle-nerve cells (organoids) to better understand severe, hard-to-treat myasthenia gravis. It may help researchers find new treatment options for people with the AChR antibody type.
MilanAges 18 years+ - NCT07715838Recruiting
PEM as a starting point to study ME/CFS
This study looks at how post-exertional malaise (PEM) affects people with ME/CFS. It aims to understand the condition better and find new ways to help.
GroningenAges 18–65 - NCT03887273RecruitingPhase 1/Phase 2
Cell transplant study for transverse myelitis patients
This trial tests if transplanting special cells into the spine is safe for people with transverse myelitis (a rare spinal cord inflammation) that has caused long-term weakness or trouble walking. It aims to see if these cells can help improve function.
Dallas, TexasAges 18–70 - NCT07280351Enrolling by invitation
Duraplasty for acute spinal cord injury
This trial tests whether adding a special patch (duroplasty) during emergency spinal surgery helps people recover from a recent traumatic spinal cord injury. It's for patients who need decompression surgery within 24 hours of injury.
San Francisco, CaliforniaAges 18–80 - NCT04798690Recruiting
Long-term growth injections for short children
This trial studies the long-term safety and effectiveness of Growtropin®-II, a growth hormone–type injection, in children who are short due to certain causes. It may help your child’s growth over time, while also closely tracking side effects.
Seoul, Seodaemun-guAges 2 years+ - NCT04348747RecruitingPhase 2
Vaccine plus pembrolizumab for breast cancer in the brain
This trial studies whether a personalized immune-cell vaccine (dendritic cell vaccine) combined with pembrolizumab can help control brain metastases from certain types of breast cancer. It may help your immune system better recognize and attack cancer cells in the brain.
Tampa, FloridaAges 18 years+ - NCT07136740Recruiting
Biofeedback for preventing tension headaches
This study tests whether a smartphone app that teaches you biofeedback (a way to relax muscles using sensors) can help prevent tension headaches. You will use the app at home to practice techniques and track your headaches.
NamsosAges 18 years+ - NCT07657897Recruiting
Anesthesia effects on inflammation in liver cancer treatment
This study looks at how different types of anesthesia or sedation affect inflammation in people with early-stage liver cancer who are having a procedure called radiofrequency ablation (RFA). RFA uses heat to destroy small tumors, and researchers want to see if the choice of anesthesia influences the body's immune response, which might help improve recovery.
Cluj-Napoca, ClujAges 18–80 - NCT07135310Recruiting
Stroke 120 action for faster treatment
This trial tests a program called STROKE 120 that teaches communities in China how to recognize stroke symptoms and call an ambulance quickly. The goal is to see if it helps people get to the hospital within 4.5 hours, which can lead to better recovery.
ShanghaiAges Any age - NCT07560306RecruitingPhase 3
New Heart Scan to Detect Blood Clots in Amyloid Heart Disease
This study tests a new type of imaging scan ([64Cu]FBP8 PET) to detect blood clots that may form in the heart's left atrial appendage (a small pouch in the heart) in patients with amyloid cardiomyopathy (a disease where abnormal protein builds up in heart muscle) who also have irregular heartbeat. The scan may help doctors catch clots earlier and prevent strokes.
Boston, MassachusettsAges 18 years+ - NCT07716930Enrolling by invitation
Eye scan study for drug-resistant epilepsy
This study uses a special eye scan (OCT) to look for changes in the retina that might be linked to hard-to-control epilepsy. The goal is to find new biomarkers that could help doctors better understand and manage the condition.
IstanbulAges 18–40 - NCT06907849Enrolling by invitationPhase 2
Imaging amyloid in spinal stenosis and carpal tunnel
This trial tests a special scan that uses a radioactive tracer to look for amyloid protein deposits in people who have had surgery for lumbar spinal stenosis (narrowing of the spine in the lower back) or carpal tunnel syndrome. The goal is to see if the scan can detect these deposits, which may be linked to ongoing orthopedic issues.
Knoxville, TennesseeAges 60 years+ - NCT07147309Recruiting
PET scans for epilepsy surgery planning
This trial tests three types of PET scans to help doctors exactly locate the part of the brain causing seizures before surgery. It's for people with epilepsy that isn't controlled by medication and who are already planning surgery or an SEEG.
Fuzhou, FujianAges 18–50 - NCT07688551RecruitingPhase 2/Phase 3
Speech therapy with brain stimulation for aphasia after stroke
This trial tests if adding a gentle brain stimulation (tDCS) to speech therapy helps people with aphasia (trouble speaking) after a stroke. If you had a stroke more than 6 months ago and have trouble naming objects, this study may be a good fit.
Charleston, South CarolinaAges 25–80 - NCT05979441Enrolling by invitationPhase 3
Long-term safety of efgartigimod injection for myositis
This study tests the long-term safety and effectiveness of a subcutaneous (under-the-skin) version of efgartigimod for adults with active idiopathic inflammatory myopathy. It is for people who have already completed an earlier study of this medicine.
Phoenix, ArizonaAges 18 years+ - NCT03582800RecruitingPhase 2
Sodium thiosulfate shots for abnormal calcium or bone spots
This pilot study tests a medicine called sodium thiosulfate (given as a skin shot) to treat abnormal calcium or bone formation in places they don’t belong. It’s meant for people whose condition is causing significant problems, and who are not planning surgery for the next year.
BordeauxAges 6 months+ - NCT07459803Recruiting
Speech motor skills study for neurotypical speakers and those with stuttering or dyslexia
This study looks at how different people control their speech muscles, comparing neurotypical speakers to adults who stutter or have dyslexia. It could help us understand why some people have trouble producing fluent speech.
Boston, MassachusettsAges 18–50 - NCT07172971RecruitingPhase 1
SGLT2i drug for heart health in Duchenne muscular dystrophy
This trial tests if an SGLT2i medication can help protect heart function in people with Duchenne muscular dystrophy (DMD). The drug is already approved for other conditions, and researchers want to see if it can slow or prevent heart muscle damage.
Nashville, TennesseeAges 8–18 - NCT07036796RecruitingPhase 2
Melatonin for diabetic nerve pain
This trial tests whether melatonin can help relieve pain and discomfort from diabetic peripheral neuropathy (nerve damage caused by diabetes). If you have type 2 diabetes with nerve pain and are on stable diabetes medications, you may be eligible.
CairoAges 40–75
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,420 recruiting neurology studies from the U.S. registry right now, out of 19,378 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.