Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,941 recruiting studies in this area right now.
By phase
- Not applicable9,343
- Phase 2764
- Phase 1557
- Phase 3513
- Phase 4339
- Phase 1/Phase 2300
- Phase 2/Phase 3125
Top conditions
- Stroke796
- Parkinson Disease395
- Alzheimer Disease338
- Multiple Sclerosis329
- Dementia226
- Epilepsy193
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke139
- Sarcopenia135
- Mild Cognitive Impairment127
- Cerebral Palsy119
- Pain Management114
- Migraine107
- Fibromyalgia104
Leading sponsors
- Beijing Tiantan Hospital124
- Assistance Publique - Hôpitaux de Paris109
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California659
- Massachusetts305
- New York294
- Florida271
- Texas266
- Maryland248
- Alabama207
- Arizona207
- Illinois181
- Pennsylvania176
Recruiting studies11,941 total
- NCT07579871Recruiting
Sleep patterns and recovery after first stroke
This study looks at how sleep affects recovery in people who have had their first ischemic stroke (a stroke caused by a blood clot). Researchers want to understand whether sleep quality influences how well patients regain function after stroke.
Lund, Skåne CountyAges 18 years+ - NCT04611009RecruitingPhase 2
Video training for writer’s cramp with attention and movement practice
This trial tests a video-guided program to improve hand control and awareness for people with writer’s cramp. It may help reduce crampy, involuntary hand movements by teaching safer, more coordinated practice.
Kiel, Schleswig-HolsteinAges 18–80 - NCT06723353Recruiting
Combined therapy for belly separation in new mothers
This trial tests if a gentle hands-on treatment (visceral manipulation) plus special tape (kinesio taping) can help close the gap in your belly muscles, reduce pain, stop bladder leaks, and improve your pelvic floor strength and overall well-being after childbirth.
Karachi, SindhAges 35–45 - NCT04628429Recruiting
Study CGRP blocker effects on migraine and body nerve function
This study tests a CGRP-blocking antibody to see how it affects migraine symptoms and the body’s automatic (involuntary) nerve functions. It may help people with migraine who have already tried several preventive medicines.
ViennaAges 18–64 - NCT06375447Recruiting
Smart model for diagnosing and treating insomnia
This trial is testing a new intelligent approach to diagnose and treat insomnia. If you have trouble sleeping and are between 18 and 75, you may be able to join and help improve insomnia care.
BeijingAges 18–75 - NCT03988764Recruiting
Checking monogenic diabetes wrongly labeled as type 1
This trial looks at people who were diagnosed with diabetes before age 25 as either type 1 or “not sure which type.” It may help confirm whether the cause is genetic (monogenic) rather than type 1, which can change treatment choices.
Montreal, QuebecAges 1 day–25 years - NCT05778981Recruiting
Study of blood-vessel health during non-heart surgery
This study looks at how blood-vessel function changes around the time of non-heart surgery, especially in people 45 and older. It may help doctors better understand risks and recovery related to blood-vessel stress during hospitalization.
Independencia, Santiago MetropolitanAges 45 years+ - NCT06418594RecruitingPhase 2
Drug combo for HER2-negative breast cancer brain metastasis
This trial tests a combination of two drugs (adebrelimab and apatinib) plus chemotherapy for women with HER2-negative breast cancer that has spread to the brain. It aims to see if this treatment can help shrink or control brain tumors.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06725966Recruiting
Personalized treatment for persistent BPPV
This trial tests a new way to treat a common inner ear condition called BPPV that hasn't improved with standard head maneuvers. It aims to help people whose dizziness keeps coming back.
Santiago de Compostela, A CoruñaAges 18–100 - NCT06474884Recruiting
Single blood thinner after shielded stent for brain aneurysm
This study is testing whether using only one blood-thinning medication (single antiplatelet therapy) after placing a special stent (Pipeline Flex with Shield) is safe and effective for treating unruptured brain aneurysms. It is for people who have already been on two blood thinners for a few days before the stent placement.
BeijingAges 18–80 - NCT06633003Recruiting
Testing an oral extract for spinocerebellar ataxia
This trial tests whether an oral extract from a mushroom called Antrodia cinnamomea can help improve symptoms in people with spinocerebellar ataxia (a condition that affects coordination and balance). Participants must be able to communicate in Chinese.
TaipeiAges 30–70 - NCT06725836Recruiting
Spinal cord stimulation study for spinal cord injury
This study tests how spinal cord stimulation affects brain activity in people with spinal cord injuries. It aims to understand the physiological effects using EEG (a brainwave test).
Vladivostok, Primorskiy (Maritime) KrayAges Any age - NCT04007380Recruiting
Sleep problems after spinal cord injury study
This study looks at how sleep-disordered breathing (breathing problems during sleep) affects mood, thinking, and behavior after a spinal cord injury. It may help researchers understand the impact of these sleep breathing issues and guide better support for people after injury.
Toronto, OntarioAges 18 years+ - NCT07572071RecruitingPhase 1
Cell transplant study for moderate Parkinson's disease
This trial tests whether transplanting specially grown cells (DopaCell) into the brain can safely help people with moderate Parkinson's disease whose symptoms aren't well controlled by medication. The cells are intended to produce dopamine, the chemical that Parkinson's affects.
ShirazAges 30–70 - NCT02846272Recruiting
Brain scans in children with hard-to-treat epilepsy
This study uses special brain imaging to look at how brain cells and networks work in children with intractable, or hard-to-treat, epilepsy. The goal is to connect the scan findings with what’s found in clinical evaluation to better understand the condition.
Houston, TexasAges birth–18 years - NCT07570264Recruiting
LEXURE device training for stroke-related speech problems
This study tests whether a device or workbook-based training called LEXURE can help people who lost the ability to speak or understand words after a stroke. If you had a stroke at least 3 months ago and struggle with language, this trial may help you regain some communication skills.
Ansan, Gyeonggi-doAges 19 years+ - NCT07571005RecruitingPhase 3
Testing a New Weight-Loss Medicine for Sleep Apnea
This study tests whether a new injectable medicine called NNC0487-0111 helps people with excess weight and moderate-to-severe obstructive sleep apnea (a condition where breathing stops repeatedly during sleep) lose weight and improve their sleep apnea—without needing a CPAP machine. The goal is to see if better weight loss can reduce sleep apnea symptoms.
San Diego, CaliforniaAges 18 years+ - NCT07571174RecruitingPhase 1
ALS Study: Testing a New Drug in Spinal Fluid
This is a follow-up study for people with ALS (a disease affecting nerve and muscle control) who completed a previous trial called OWAA. Researchers want to test how a new experimental drug called LY4256984 affects the spinal fluid around your brain and spine, which may help them understand if it could slow disease progression.
LeuvenAges 18–80 - NCT07573150Recruiting
Pupil Measurements to Predict Breathing Problems After Surgery in Children
This study tests whether measuring how a child's pupils (the dark circles in the eyes) respond to light can predict which children might have breathing problems after receiving pain medication during tonsil surgery. The goal is to help doctors catch and prevent serious breathing issues before they happen.
San Francisco, CaliforniaAges 3–17 - NCT07573631Enrolling by invitationPhase 2
Long-term Safety Study of BMN 351 for Duchenne Muscular Dystrophy
This study continues treatment with an investigational medicine called BMN 351 for people with Duchenne muscular dystrophy (a genetic muscle-weakening condition). It checks whether the medicine remains safe and effective when used over a longer period, building on results from an earlier trial.
Milan, ItalyAges 4 years+ - NCT07575984RecruitingPhase 4
Mexidol Safety and Efficacy for Acute Ischemic Stroke
This trial tests whether Mexidol, a medication that may protect brain tissue, can help people recover better after an acute ischemic stroke (a type of stroke caused by a blood clot). The study includes stroke patients and healthy volunteers to understand how the drug works and if it's safe.
ArkhangelskAges 18–90 - NCT07572357Recruiting
Testing a New Self-Fit Hearing Aid with a Smartphone App
This study evaluates the RH210 hearing aid, which you fit yourself using a smartphone app. It's designed for people with mild-to-moderate hearing loss who want a simpler, app-based approach to managing their hearing.
Macquarie Park, New South WalesAges 18 years+ - NCT07569042RecruitingPhase 1/Phase 2
Continuing NBM-BMX and Temozolomide for Glioblastoma
This is a continuation study for patients who completed or are in the parent trial testing NBM-BMX (an experimental drug) combined with temozolomide (a standard brain-tumor chemotherapy) for newly diagnosed glioblastoma. If you tolerated the earlier treatment well and your doctor believes you could benefit, you may continue the same drugs in this rollover study.
Kaohsiung CityAges 18 years+ - NCT07571161RecruitingPhase 3
Donanemab for early Alzheimer's disease in Chinese participants
This trial tests a drug called donanemab in people who have early signs of Alzheimer's disease (amyloid buildup in the brain) but are still thinking clearly. The goal is to see if the drug can slow or prevent cognitive decline before memory problems start.
BeijingAges 55–80
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,941 recruiting neurology studies from the U.S. registry right now, out of 18,432 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.