Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,420 recruiting studies in this area right now.
By phase
- Not applicable9,752
- Phase 2783
- Phase 1576
- Phase 3536
- Phase 4343
- Phase 1/Phase 2307
- Phase 2/Phase 3123
Top conditions
- Stroke844
- Parkinson Disease426
- Alzheimer Disease342
- Multiple Sclerosis341
- Dementia227
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea156
- Insomnia155
- Spinal Cord Injuries153
- Traumatic Brain Injury150
- Sarcopenia149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment130
- Migraine113
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California679
- Massachusetts300
- New York292
- Florida275
- Texas266
- Maryland246
- Arizona213
- Alabama210
- Illinois187
- Pennsylvania178
Recruiting studies12,418 total
- NCT07711639Recruiting
Tinnitus treatment with nerve stimulation
This trial tests a non-invasive treatment that stimulates a nerve in your ear or foot (called taVNS) to see if it helps reduce tinnitus. It is for people whose main problem is tinnitus and who have normal hearing in both ears.
Hualien CityAges 18–75 - NCT07709975Recruiting
Pain relief and early movement for older ICU patients
This study tests different ways to manage pain and help older patients get moving again sooner after major surgery. If you are 65 or older and in the ICU, this trial may help you recover more comfortably and quickly.
Istanbul, IstanbulAges 65 years+ - NCT02359812Recruiting
Robot-assisted arm and hand rehab after recent stroke
This study tests whether a robot-guided therapy program can help people regain arm and hand movement after a recent stroke. You may be able to join if you are within a month of a first stroke on one side and have specific levels of arm and hand recovery.
Baltimore, MarylandAges 18–85 - NCT07571200RecruitingPhase 1
Study of LY4256984 for ALS in Previous Trial Participants
This is a follow-up study for people with ALS who have already completed another Eli Lilly ALS treatment trial. Researchers want to continue testing a new drug (LY4256984) in people who tolerated the previous treatment well.
LeuvenAges 18–80 - NCT07347665Recruiting
Endovascular therapy for M2 segment stroke
This study tests whether a minimally invasive procedure to remove a blood clot from a specific branch of a brain artery (the M2 segment) helps people recover from a stroke better than standard care alone. It is for people who have had a moderate to severe stroke within the past 24 hours and could not get clot-dissolving medicine or it didn't work.
Nishinomiya, HyōgoAges 18–84 - NCT06595914Enrolling by invitation
Improving education for mild traumatic brain injury
This trial is working to improve how doctors and nurses teach patients about mild traumatic brain injury (mTBI) in the emergency room and after they go home. It may help you get clearer information and support during recovery.
Milwaukee, WisconsinAges 18 years+ - NCT07234357Recruiting
Scent therapy for mood and behavior in early dementia
This trial uses pleasant scents (aromatherapy) to see if they can improve mood and behavior for people with early memory loss. It is designed for individuals who have a caregiver who can help them participate.
SingaporeAges 50–99 - NCT06465290Recruiting
Brain recovery treatment for recent stroke with ankle stiffness
This trial tests a treatment to help your brain recover after a stroke. It focuses on improving ankle movement and leg strength using exercises that promote brain rewiring.
Baltimore, MarylandAges 30–85 - NCT06723106Enrolling by invitationPhase 1
Long-term safety study of RAY121 for immune conditions
This study is for people who already took RAY121 in a previous trial and did well. It tests whether continuing the treatment is safe and effective over a longer period. The goal is to manage chronic immune conditions.
Camperdown, New South WalesAges 18–85 - NCT01524276Recruiting
Registry to track outcomes of Medtronic medical devices
This is a follow-up registry that collects information from people who have (or will receive) an eligible Medtronic device. It helps the company and doctors better understand how the device works in real-world use.
Birmingham, AlabamaAges Any age - NCT05980052Recruiting
Goal setting to boost activity in midlife adults
This study tests whether setting goals helps people in midlife become more physically active. If you are between 45 and 65, have a higher weight, and currently do not exercise much, this program may help you build a healthier habit.
Phoenix, ArizonaAges 45–65 - NCT05139290Enrolling by invitation
Support for African American families managing dementia care decisions
This study focuses on helping African American people with mild to moderate dementia and their family caregivers make better care decisions together. It also includes people who help with navigating healthcare when dementia care becomes harder.
Washington D.C., District of ColumbiaAges 18 years+ - NCT02359253Recruiting
Robot-assisted arm therapy after a recent stroke
This study tests whether robot-guided therapy can improve arm and hand recovery after a stroke. You may be a candidate if your stroke was recent and you still have certain levels of arm weakness and movement.
Baltimore, MarylandAges 18–85 - NCT07571174RecruitingPhase 1
ALS Study: Testing a New Drug in Spinal Fluid
This is a follow-up study for people with ALS (a disease affecting nerve and muscle control) who completed a previous trial called OWAA. Researchers want to test how a new experimental drug called LY4256984 affects the spinal fluid around your brain and spine, which may help them understand if it could slow disease progression.
LeuvenAges 18–80 - NCT07706296Recruiting
Hand function tests for carpal tunnel syndrome
This study tests whether certain hand function tests are reliable and accurate for people with carpal tunnel syndrome. It helps doctors better understand how the condition affects your hand use.
IzmirAges 18–60 - NCT03952299RecruitingPhase 3
Oxybutynin patch after bladder surgery for children’s urgency pain
This study tests whether an oxybutynin skin patch after bladder surgery can reduce bladder pain and urgent, frequent urination in children. It compares symptoms after surgery to see if the patch helps more than the control plan.
Sacramento, CaliforniaAges 4–8 - NCT07707076Recruiting
Flow diverter vs standard treatment for wide-neck brain aneurysms
This trial compares a flow diverter device to standard endovascular treatment for unruptured wide-neck brain aneurysms at a bifurcation. If you have this type of aneurysm, this study may help determine which treatment works better.
Guangzhou, GuangdongAges 18–75 - NCT07252440RecruitingPhase 2
Testing an oral drug for early Alzheimer's disease
This study tests an oral tablet (TTYP01) for people with early Alzheimer's disease. It aims to see if the drug can slow memory loss. You must have a study partner who can support you throughout the trial.
Chongqing, Chongqing MunicipalityAges 55–85 - NCT06806761Recruiting
Tracking balance and walking after stroke
This study tracks how walking and balance improve in the first weeks after a stroke. It uses simple tests to measure your recovery over time, with no experimental treatments.
Sint-Pieters-Leeuw, Brussels CapitalAges 18 years+ - NCT07707609Recruiting
Pain and brain changes in chronic pancreatitis
This study looks at how chronic pancreatitis pain affects the nervous system and mental health. It aims to understand pain better and may help develop new ways to manage it.
Hyderabad, TelanganaAges 18–60 - NCT07707453Recruiting
Studying work and well-being of internal medicine residents
This study follows resident doctors in general internal medicine over time to understand their professional and personal experiences, including stress and career growth. It aims to improve support for doctors in training.
BernAges Any age - NCT06979089Recruiting
Stress relief program for Dutch SMEs
This trial tests an online stress-management program for employees in small to medium-sized businesses in the Netherlands. It aims to help people with high stress levels feel better and cope more effectively.
Amsterdam, North HollandAges 18 years+ - NCT07709143Recruiting
MRI study of balance disorders in older adults
This study uses MRI scans to look at the brain and inner ear in people with balance problems called bilateral vestibulopathy and presbyvestibulopathy. It aims to understand risk factors and improve diagnosis.
Shanghai, Shanghai MunicipalityAges 16 years+ - NCT07707700Recruiting
Training program for reading skills in children with dyslexia
This trial tests a new training program designed to improve visual attention and reading skills in Chinese children with dyslexia. It may help if your child is struggling with reading and has been formally diagnosed.
Hong KongAges 7–10
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,420 recruiting neurology studies from the U.S. registry right now, out of 19,378 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.