Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,941 recruiting studies in this area right now.
By phase
- Not applicable9,343
- Phase 2764
- Phase 1557
- Phase 3513
- Phase 4339
- Phase 1/Phase 2300
- Phase 2/Phase 3125
Top conditions
- Stroke796
- Parkinson Disease395
- Alzheimer Disease338
- Multiple Sclerosis329
- Dementia226
- Epilepsy193
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke139
- Sarcopenia135
- Mild Cognitive Impairment127
- Cerebral Palsy119
- Pain Management114
- Migraine107
- Fibromyalgia104
Leading sponsors
- Beijing Tiantan Hospital124
- Assistance Publique - Hôpitaux de Paris109
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California659
- Massachusetts305
- New York294
- Florida271
- Texas266
- Maryland248
- Alabama207
- Arizona207
- Illinois181
- Pennsylvania176
Recruiting studies11,941 total
- NCT07573059Recruiting
Safety study of a test system for Loargys-treated patients
This study evaluates whether a new test system is safe to use in patients who are already taking Loargys (a medicine for a rare condition called ARG1-D, which affects how the body processes a protein building block called arginine). The study simply observes how the test system works in people already on this treatment.
Atlanta, GeorgiaAges birth–100 years - NCT07571200RecruitingPhase 1
Study of LY4256984 for ALS in Previous Trial Participants
This is a follow-up study for people with ALS who have already completed another Eli Lilly ALS treatment trial. Researchers want to continue testing a new drug (LY4256984) in people who tolerated the previous treatment well.
LeuvenAges 18–80 - NCT07571161RecruitingPhase 3
Donanemab for early Alzheimer's disease in Chinese participants
This trial tests a drug called donanemab in people who have early signs of Alzheimer's disease (amyloid buildup in the brain) but are still thinking clearly. The goal is to see if the drug can slow or prevent cognitive decline before memory problems start.
BeijingAges 55–80 - NCT07571005RecruitingPhase 3
Testing a New Weight-Loss Medicine for Sleep Apnea
This study tests whether a new injectable medicine called NNC0487-0111 helps people with excess weight and moderate-to-severe obstructive sleep apnea (a condition where breathing stops repeatedly during sleep) lose weight and improve their sleep apnea—without needing a CPAP machine. The goal is to see if better weight loss can reduce sleep apnea symptoms.
San Diego, CaliforniaAges 18 years+ - NCT02535936Recruiting
Brain plasticity study after rhizotomy surgery for spastic diplegia
This study looks at how the brain adapts after selective dorsal rhizotomy surgery in children with spastic diplegia. It may help doctors better understand recovery and treatment effects over time.
Houston, TexasAges 3–18 - NCT03356392Recruiting
Registry for stroke patients getting clot-busting treatment
This study records information from adults with an acute ischemic stroke (a stroke caused by a blocked artery) who receive clot-busting medicine within 4.5 hours. It may help doctors better understand which patients benefit from treatment and how care decisions are made for certain blocked brain arteries.
Hamburg, Free and Hanseatic City of HamburgAges 18 years+ - NCT05027035Recruiting
Compare diaphragm surgery versus breathing machine support
This trial is studying whether surgery, instead of using a breathing machine, works better for people with one-sided diaphragm paralysis. It aims to improve breathing comfort and function in the right patients.
GroningenAges 18 years+ - NCT05024981Recruiting
Video-based feedback and walking rehab after stroke
This trial tests whether using video feedback during walking therapy can help people regain safer walking after a recent stroke. You may be asked to walk while being video-recorded so therapists can guide your practice.
Nice, Alpes-MaritimeAges 70 years+ - NCT05385315Recruiting
Blood test study to help detect Parkinson’s disease early
This study looks for a new blood marker that could help doctors detect Parkinson’s disease earlier. Depending on your diagnosis and treatment status, your blood may be compared with other people’s to see how well the test works.
GrenobleAges 18 years+ - NCT05473689Recruiting
Sleep study in early spinal cord injury
This study looks at how sleep quality affects movement problems after a new spinal cord injury. Researchers hope to identify sleep targets that could improve motor function during recovery.
Toronto, OntarioAges 18 years+ - NCT07568470Enrolling by invitation
Testing a new sign for foot drop nerve problems
This trial tests whether a simple physical exam sign (the Phoenix Sign) can help diagnose a specific nerve problem that causes foot drop. Researchers will use a safe sugar solution to see if this sign appears.
Marietta, GeorgiaAges Any age - NCT07570472RecruitingPhase 2
CBD and sleep quality after evening exercise
This study tests whether CBD (cannabidiol, a compound from cannabis plants) can improve sleep quality after evening workouts in healthy, active adults. Researchers want to see if CBD helps you sleep better on nights when you exercise late.
Leuven, Vlaams-BrabantAges 18–40 - NCT07570589Recruiting
Tracking myasthenia gravis symptoms on rozanolixizumab treatment
This study follows patients with generalized myasthenia gravis (a condition where muscles weaken over time) who have specific antibodies and are being treated with rozanolixizumab, a medication that helps reduce symptom severity. Researchers will monitor how symptoms change in real-world settings.
Nice, Alpes-maritimesAges 18 years+ - NCT07576426Recruiting
Shoulder Exercises for Breastfeeding Women With Shoulder Pain
This study tests whether specific shoulder and upper-back exercises can reduce pain in women who are breastfeeding and have a condition called scapular dyskinesia, where the shoulder blade doesn't move properly. The goal is to help you feel better during and after breastfeeding.
Lahore, Punjab ProvinceAges 20–40 - NCT07572734Recruiting
Breathing exercises to help after a concussion in teens
This study tests whether special breathing exercises can help the nervous system recover better after a concussion. Kids ages 9–18 who come to the emergency room within 3 days of a concussion may qualify if they have symptoms like dizziness, nausea, tiredness, confusion, anxiety, or sleep problems.
Montreal, QuebecAges 9–18 - NCT07575347Recruiting
Gum Disease and Rare Kidney Disorders Study
This study explores whether people with certain rare kidney diseases or chronic kidney problems have more gum disease than others. Researchers will examine your teeth and gums to understand the connection and help improve care for people with kidney conditions.
BucharestAges 18 years+ - NCT07570459Recruiting
Understanding Tremor in Charcot-Marie-Tooth Disease
This study examines tremor (involuntary shaking) in people with Charcot-Marie-Tooth disease, a genetic nerve condition that affects the legs and feet. Researchers will compare people with CMT who have tremor to healthy volunteers to better understand this symptom.
Göttingen, Lower SaxonyAges 18–65 - NCT07571538Recruiting
A new eye test to reduce ghosting or double vision
This study tests a new way to reduce 'ghosting'—double or shadow images—that some people see, especially with astigmatism or at night. It involves using a special visual test to measure and possibly correct this effect.
Bloomington, IndianaAges 8 years+ - NCT07574164Recruiting
Brain Stimulation to Reduce Tremor in Parkinson's or Essential Tremor
This trial tests a new type of brain stimulation called closed-loop TMS that automatically adjusts to help reduce tremor in people with Parkinson's disease or essential tremor. The goal is to see if this technology can better control shaking than standard treatments.
Oxford, OxfordshireAges 18 years+ - NCT07570719Recruiting
Community screening for early Alzheimer's disease signs
This study screens people aged 60–80 for early signs of Alzheimer's disease in a community setting. Researchers will ask you questions and may perform brain imaging to understand who might benefit from early detection and treatment.
Shanghai, Shanghai MunicipalityAges 60–80 - NCT07569952Recruiting
Nerve Block to Improve Surgical Field in Pituitary Surgery
This trial tests whether blocking a specific nerve in the face (sphenopalatine ganglion) during pituitary tumor surgery improves the surgeon's view and reduces bleeding. Pituitary adenomas are non-cancerous tumors in the brain that are removed through the nose using a camera.
CairoAges 1.8 years–60 years - NCT07571707Recruiting
Lollipops to Reduce Confusion After Surgery in Young Children
This study tests whether giving children a lollipop after surgery helps prevent confusion and agitation as they wake up from anesthesia. Emergence delirium—when children are disoriented and upset after anesthesia—is common, and the researchers want to see if this simple comfort measure helps.
Denpasar, BaliAges 2–6 - NCT07570446Recruiting
Autonomic Function in Charcot-Marie-Tooth Disease
This study examines how autonomic nerves (the nerves that control automatic body functions like heart rate and blood pressure) are affected in people with CMT (Charcot-Marie-Tooth disease), a genetic nerve disorder. Understanding this may help improve treatment and quality of life for CMT patients.
Göttingen, Lower SaxonyAges 18–65 - NCT07568938Recruiting
Anesthesia types and stress response in weight-loss surgery
This study compares two anesthesia methods—inhaled gas (desflurane) versus IV medication (TIVA)—during weight-loss surgery to see how each affects your body's stress response and recovery. The goal is to understand which approach may be safer and more comfortable for patients having bariatric surgery.
AthensAges 18–65
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,941 recruiting neurology studies from the U.S. registry right now, out of 18,432 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.