Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,420 recruiting studies in this area right now.
By phase
- Not applicable9,752
- Phase 2783
- Phase 1576
- Phase 3536
- Phase 4343
- Phase 1/Phase 2307
- Phase 2/Phase 3123
Top conditions
- Stroke844
- Parkinson Disease426
- Alzheimer Disease342
- Multiple Sclerosis341
- Dementia227
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea156
- Insomnia155
- Spinal Cord Injuries153
- Traumatic Brain Injury150
- Sarcopenia149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment130
- Migraine113
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California679
- Massachusetts300
- New York292
- Florida275
- Texas266
- Maryland246
- Arizona213
- Alabama210
- Illinois187
- Pennsylvania178
Recruiting studies12,418 total
- NCT07435649Recruiting
New test for finding germs in spinal fluid during brain infections
This study tests a new type of test called Delve Detect that looks for germs in spinal fluid from people suspected of having a brain or spinal cord infection. It helps doctors find the cause faster and more accurately.
San Francisco, CaliforniaAges Any age - NCT06047379RecruitingPhase 1/Phase 2
Testing NEO212 for brain tumors and metastases
This trial tests a new drug called NEO212 for people with certain brain tumors (like astrocytoma or glioblastoma) or cancer that has spread to the brain from other parts of the body. The goal is to see if it is safe and if it can help shrink or control the tumors.
Beverly Hills, CaliforniaAges 18 years+ - NCT07299994Recruiting
Intravenous thrombolysis for specific brain strokes
This trial tests whether a clot-busting drug given through a vein can help people with certain types of deep brain strokes that happen in small arteries. It looks at patients who can be treated within 24 hours of symptoms starting.
Vienna, State of ViennaAges 18 years+ - NCT07337226Recruiting
Vagus nerve stimulation and treadmill training for Parkinson's walking
This study tests whether a mild electrical stimulation on the ear (called taVNS) combined with treadmill walking can improve walking ability in people newly diagnosed with Parkinson's disease. The goal is to see if this combination helps you walk better and more safely.
Roma, RMAges 50–80 - NCT07278440Recruiting
Exercise program for brain tumor patients and their partners
This study tests if a home exercise program can improve mental and physical health for people with brain tumors and their live-in partners. Both of you will be guided through exercise sessions together over video.
Portland, OregonAges 18 years+ - NCT07113470Recruiting
Nerve stimulation for chronic cluster headache prevention
This trial tests if a device that stimulates nerves on your face and the back of your head can prevent chronic cluster headaches. It may offer a new treatment option if you have had cluster headaches for at least a year.
LeidenAges 18 years+ - NCT02544022Recruiting
Testing and validating pain and symptom questionnaires for NF1
This study checks whether patient surveys (questionnaires) can reliably measure symptoms and pain in people with NF1 who have plexiform neurofibromas. It helps create better tools for tracking how you feel and how treatments may affect quality of life.
Washington D.C., District of ColumbiaAges 5 years+ - NCT05907629Recruiting
MRI study comparing blood thinners after a certain stroke
This trial looks at MRI scans to compare two types of blood-thinning medicines (one that affects blood-clotting and one that affects platelets) after a recent stroke caused by severe narrowing in certain brain arteries. It may help doctors understand which treatment works best while checking how the blood vessels and brain tissue look on MRI.
Birmingham, AlabamaAges 18 years+ - NCT07299981Recruiting
Brain water changes after clot-busting drug for stroke
This study looks at how much water builds up in brain tissue after a stroke is treated with a clot-busting drug. It may help doctors understand who will recover better.
ViennaAges 18 years+ - NCT05933629Recruiting
Training mental health providers to deliver an online TBI group program
This study helps test whether community mental health clinicians can learn and successfully deliver an online emotion-regulation group program for people with traumatic brain injury (TBI). It may help improve access to structured support when in-person group care is hard to reach.
New York, New YorkAges 18 years+ - NCT07543692Recruiting
Ultrasound-guided injection therapy for spine pain
This study tests whether using ultrasound imaging to guide a special injection treatment (pharmacopuncture) is safe and effective for people with spine-related neck or lower back pain that radiates into the arms or legs. The treatment is already being offered as routine care, and this study tracks how well it works.
Daejeon, DaejeonAges 19–69 - NCT03344276Recruiting
Testing thinking and memory after carotid artery treatment
This study checks how a carotid artery procedure affects thinking and memory. You may be able to join if you’re an adult with significant carotid artery narrowing seen on ultrasound, and you can safely do follow-up MRI scans.
San Diego, CaliforniaAges 18 years+ - NCT05951777RecruitingPhase 2
Stem cells from your own fat for chronic brain injury
This trial tests whether stem cells taken from your own fat and given through an IV can help people with long-term brain damage from a head injury. It is for adults who have not gotten better with standard treatments.
Houston, TexasAges 18–55 - NCT07236515Recruiting
Leia device for balance in peripheral neuropathy
This trial tests a device called the Leia Sensory Prosthesis, which may help people with peripheral neuropathy improve their balance and walking. It compares the active device to a placebo (sham) to see if it reduces falls and improves stability.
MeyrinAges 18 years+ - NCT06780150Recruiting
Ocrelizumab effects on nerve health and satisfaction in MS
This study looks at how ocrelizumab treatment affects a nerve health marker called neurofilament light chain (NfL) and how satisfied you are with the treatment. It may help doctors understand if this medicine works well for people with multiple sclerosis.
AachenAges 18 years+ - NCT04948749Recruiting
Stenting plus medication to prevent stroke from narrowed brain arteries
This trial tests whether placing a stent in a severely narrowed brain artery, along with aggressive medication, can prevent another stroke better than medication alone. It is for people who had a mild stroke within the last 30 days due to a 70-99% blockage in a major brain artery.
Beijing, Beijing MunicipalityAges 18–85 - NCT07488377Recruiting
Cognitive Self-Confidence in Parkinson's Disease
This study tests a new questionnaire to measure how confident people with Parkinson's feel about their thinking and memory. It may help doctors better understand and support cognitive changes in Parkinson's.
Istanbul, TurkeyAges 40–85 - NCT07488364Recruiting
Understanding frailty in Parkinson's disease
This study looks at why some people with Parkinson's disease become physically frail. It aims to find factors that may help predict or prevent frailty.
Istanbul, TurkeyAges 40–85 - NCT07488351Recruiting
Self-kindness and confidence in Parkinson's: symptoms, function, quality of life
This study looks at how self-compassion and self-belief affect symptoms, daily function, and quality of life in people with Parkinson's disease. It aims to help researchers understand how emotional well-being relates to physical health.
Istanbul, TurkeyAges 40–85 - NCT07705542Recruiting
Balloon use during biofeedback for constipation
This study tests whether using a balloon during biofeedback therapy helps people with constipation caused by pelvic floor dysfunction. It's for people who have trouble relaxing their pelvic floor muscles during bowel movements.
HullAges 18 years+ - NCT07453888RecruitingPhase 3
Nose spray for sudden vision loss from optic nerve damage
This trial tests a nose spray medication (cenegermin) for people who recently lost vision due to a specific type of optic nerve damage (NAION). The goal is to see if it can help restore sight when started within two weeks of vision loss.
Los Angeles, CaliforniaAges 50–80 - NCT07704931Enrolling by invitation
Can spinal cord stimulation repair small nerve fibers?
This study tests whether a special type of spinal cord stimulation (which uses mild electrical pulses to block pain) can help repair damaged small nerve fibers in people with small fiber neuropathy. If you have chronic nerve pain and meet the criteria, you may be able to join.
Grand Island, NebraskaAges 19 years+ - NCT04538755Enrolling by invitationPhase 1/Phase 2
Testing a new drug for moderate to severe sleep apnea
This trial tests a drug called DAW2020 to see if it can improve how your body controls breathing during sleep. You may qualify if you have moderate to severe sleep apnea and are otherwise healthy.
Boston, MassachusettsAges 21–70 - NCT06911229Recruiting
Walking and freezing study for Parkinson's with DBS
This study looks at how the brain controls walking and freezing of gait in people with Parkinson's disease who have deep brain stimulation (DBS). It aims to help understand why freezing happens and improve treatments.
Gainesville, FloridaAges 18–80
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,420 recruiting neurology studies from the U.S. registry right now, out of 19,378 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.