Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,420 recruiting studies in this area right now.
By phase
- Not applicable9,752
- Phase 2783
- Phase 1576
- Phase 3536
- Phase 4343
- Phase 1/Phase 2307
- Phase 2/Phase 3123
Top conditions
- Stroke844
- Parkinson Disease426
- Alzheimer Disease342
- Multiple Sclerosis341
- Dementia227
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea156
- Insomnia155
- Spinal Cord Injuries153
- Traumatic Brain Injury150
- Sarcopenia149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment130
- Migraine113
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California679
- Massachusetts300
- New York292
- Florida275
- Texas266
- Maryland246
- Arizona213
- Alabama210
- Illinois187
- Pennsylvania178
Recruiting studies12,418 total
- NCT07011173RecruitingEarly Phase 1
Arm Muscle Coordination After Stroke
This early-phase study looks at how your muscles work together during arm movements after a stroke. It may help find better ways to improve arm and hand function.
Washington D.C., District of ColumbiaAges 20–80 - NCT07628829Recruiting
Video AI to Monitor Newborn Brain Health
This study uses artificial intelligence to watch and analyze videos of newborns in the hospital nursery or NICU to help doctors spot neurological problems early. The goal is to see if this video AI tool can safely and accurately help care for newborns during their hospital stay.
New York, New YorkAges Any age - NCT06403345Recruiting
Green activity program for memory challenges
This study tests a green activity program for people with memory challenges. You and a friend or family member will take part in outdoor activities to see if they help with thinking and well-being.
Bloomington, IndianaAges 45 years+ - NCT06812078RecruitingPhase 2
TAK-360 for idiopathic hypersomnia
This study tests an investigational medication called TAK-360 for people with idiopathic hypersomnia (IH), a sleep disorder that causes excessive daytime sleepiness. The goal is to see if the drug can help reduce sleepiness and improve daily function.
Redwood City, CaliforniaAges 18–70 - NCT07482176RecruitingPhase 3
Gene therapy trial for wet age-related macular degeneration
This trial tests a one-time gene therapy injection (IXO-vec) for people with wet age-related macular degeneration (nAMD). It aims to reduce the need for frequent eye injections by helping the eye make its own medicine to block the growth of harmful blood vessels.
Mesa, ArizonaAges 50 years+ - NCT07112365RecruitingPhase 4
Study of fenfluramine to prevent SUDEP in Dravet syndrome
This study tests whether the drug fenfluramine can reduce the risk of sudden unexpected death (SUDEP) in people with Dravet syndrome who have generalized convulsive seizures. It aims to see if a lower dose can still prevent seizures and protect the heart and breathing during a seizure.
Houston, TexasAges 16 years+ - NCT06383806Recruiting
Reducing nightmares in adults with narcolepsy
This study tests a new behavioral treatment to reduce nightmares in adults with narcolepsy. It aims to help you sleep better and feel more rested.
Salt Lake City, UtahAges 18 years+ - NCT07110454Recruiting
Long-term follow-up study for epilepsy monitoring implant
This study follows people who previously enrolled in the DETECT study and had a Minder device implanted to monitor brain activity. The goal is to see how the device performs over a longer period of time.
Phoenix, ArizonaAges 18–75 - NCT07029243Recruiting
Prehabilitation and supplement for frail cirrhosis patients
This study tests whether a prehabilitation program (exercise and nutrition planning) along with a supplement containing creatine and whey protein can help improve strength and well-being in people with cirrhosis who are frail. The goal is to see if this combination can help you feel stronger and more active.
San Francisco, CaliforniaAges 18 years+ - NCT07233408Recruiting
Online tool to help adults with neurofibromatosis 1 and low health literacy
This study tests an online platform designed to help adults with neurofibromatosis 1 (NF1) who have low health literacy. The goal is to make it easier to get evidence-based care. You may be a good fit if you have an upcoming checkup with your primary care doctor.
Boston, MassachusettsAges 18 years+ - NCT04096430Recruiting
Goal-setting program for children in physical or occupational therapy
This trial tests a child-friendly goal-setting approach during pediatric rehabilitation (physical therapy and/or occupational therapy). It may help children and families plan realistic goals that make therapy more meaningful and effective.
Calgary, AlbertaAges 5–12 - NCT07583056Recruiting
Brain Stimulation Treatment for Fibromyalgia Pain
This study tests whether a non-invasive brain stimulation treatment called tDCS (transcranial direct current stimulation) can help reduce fibromyalgia pain. You'll use a small device at home that sends mild electrical currents to your scalp, and researchers will monitor your progress via video calls.
ValenciaAges 18 years+ - NCT07372430Recruiting
Nerve block comparison for buttock nerve pain
This study compares two ways of giving a numbing injection (nerve block) to treat a condition where a nerve in the low back gets pinched, causing long-term buttock or low back pain. It aims to see which method works better.
IstanbulAges 18–75 - NCT01370512Enrolling by invitationPhase 2
Droxidopa plus pyridostigmine for low blood pressure on standing
This Phase 2 study tests whether the medicines droxidopa and pyridostigmine can improve symptoms of orthostatic hypotension, which is low blood pressure when you stand up. It is designed for people whose low blood pressure is caused by problems with the nerves that control blood pressure.
Rochester, MinnesotaAges 18 years+ - NCT06924177Recruiting
Spinal cord injury diet study for wheelchair users
This study tests a special diet program for people with spinal cord injuries who use a wheelchair. It aims to see if the diet can improve health and well-being.
Dallas, TexasAges 18–65 - NCT02960737Recruiting
Training for swallowing problems after stroke
This trial studies whether a specific oral training program can improve swallowing after a stroke. It’s mainly for people whose swallowing trouble has lasted for several weeks after their stroke.
UmeåAges 18 years+ - NCT02967068Recruiting
Share your study tissue for future research
This study is a “tissue repository” that collects and stores leftover tissue from other approved VCRC studies. If you already took part in one of those studies, you may be able to let researchers use your tissue to help answer future questions.
Boston, MassachusettsAges Any age - NCT02972008Recruiting
Looking for blood markers that predict complications after TAVI
This study enrolls older adults having a minimally invasive heart valve procedure (TAVI) to find “epigenetic” risk markers—signals in the body that may predict who is more likely to have complications during the procedure. If you qualify, your blood and/or samples may be studied to improve safety for future patients.
LilleAges 70 years+ - NCT02979951Recruiting
IV fosfomycin for serious bacterial infections
This trial studies whether IV (through a vein) fosfomycin can treat severe bacterial infections in adults. It may help people whose infection is covered by the standard fosfomycin use and who need hospital-level care.
Hall in TirolAges 18 years+ - NCT02983370Recruiting
Cortical visual implant to help people with severe blindness
This trial studies a device that may help people with severe blindness by sending signals to the brain’s visual areas. You may be eligible if you’re an adult with long-term, severe vision loss and good overall health and can complete testing for several months.
Elche, AlicanteAges 18–70 - NCT02988128Recruiting
Medical device registry for Medtronic neurovascular products
This study follows people who receive a specific Medtronic neurovascular device to learn about safety and performance over time. It may help improve how these devices are used and monitored in real-world care.
Buenos AiresAges 18 years+ - NCT02991248Recruiting
Balance training for people with spinal cord injury
This study looks at a treatment to improve how well you can balance and stay steady while moving if you have a spinal cord injury. It may help with side-to-side (lateral) balance and walking control.
Chicago, IllinoisAges 18–65 - NCT02993796Recruiting
Krabbe disease patient and family registry
This registry collects information from people who have Krabbe disease, people at risk, and close family members. It helps researchers learn more about the disease and support future studies.
Buffalo, New YorkAges Any age - NCT02994121Recruiting
Study of multiple sclerosis in the Three Rivers region
This study follows people with multiple sclerosis (MS) and some healthy people in the local area to better understand MS and related nerve conditions. It may help researchers learn which symptoms and scan changes show up over time.
Pittsburgh, PennsylvaniaAges 7 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,420 recruiting neurology studies from the U.S. registry right now, out of 19,378 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.