Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,941 recruiting studies in this area right now.
By phase
- Not applicable9,343
- Phase 2764
- Phase 1557
- Phase 3513
- Phase 4339
- Phase 1/Phase 2300
- Phase 2/Phase 3125
Top conditions
- Stroke796
- Parkinson Disease395
- Alzheimer Disease338
- Multiple Sclerosis329
- Dementia226
- Epilepsy193
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke139
- Sarcopenia135
- Mild Cognitive Impairment127
- Cerebral Palsy119
- Pain Management114
- Migraine107
- Fibromyalgia104
Leading sponsors
- Beijing Tiantan Hospital124
- Assistance Publique - Hôpitaux de Paris109
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California659
- Massachusetts305
- New York294
- Florida271
- Texas266
- Maryland248
- Alabama207
- Arizona207
- Illinois181
- Pennsylvania176
Recruiting studies11,941 total
- NCT07546864Recruiting
Mirror Therapy vs. Daily Activity Training After Stroke
This study compares two rehabilitation approaches—mirror therapy (using a mirror to help retrain your affected side) and cognitive orientation to daily tasks—for people recovering from stroke. The goal is to see which method helps improve arm, hand, and leg function better.
Bayburt, MerkezAges 18 years+ - NCT07548801Enrolling by invitation
Brain Stimulation for Parkinson's Disease Movement
This study tests whether a non-invasive brain stimulation technique applied to the back of your brain (cerebellum) can help improve movement and balance in people with mild to moderate Parkinson's disease. The treatment uses a small electrical current to stimulate brain activity.
BrusselsAges 18 years+ - NCT07551141Recruiting
Vibration to Help Stroke Recovery: Balance and Walking
This study tests whether vibrations applied to the bottom of your feet can help improve walking and balance after stroke. You'll receive plantar vibration therapy (gentle vibrations under your feet) while performing walking and balance exercises to see if it helps your recovery.
BoluAges 18–75 - NCT07544602Enrolling by invitation
Music therapy for coma after head injury
This trial tests whether listening to music can help people who are in a coma after a serious head injury recover. It may help improve brain function and recovery during their stay in intensive care.
Youngstown, OhioAges 18 years+ - NCT07544082Recruiting
Acupuncture for Insomnia Related to Heart-Spleen Imbalance
This study tests whether acupuncture using traditional five-point techniques can help people with long-term insomnia, especially those experiencing poor sleep quality, nightmares, and early morning awakening. It focuses on a specific pattern in traditional Chinese medicine called Heart-Spleen deficiency.
Ho Chi Minh CityAges 18 years+ - NCT07546786Recruiting
How Meditation Affects Thinking and Emotions
This study compares how meditation affects brain function and emotional regulation in people who meditate regularly versus those who don't. Researchers want to understand if regular meditation improves focus, memory, and emotional well-being.
Boston, MassachusettsAges 18 years+ - NCT07543991RecruitingPhase 1
Gene therapy for giant axonal neuropathy via vagus nerve
This is a follow-up study for patients who previously received an experimental gene therapy (scAAV9/JeT-GAN) for giant axonal neuropathy (GAN), a rare genetic nerve disorder. The new treatment delivers the therapy directly into the vagus nerve—a major nerve in the neck—to help manage nerve damage and related symptoms.
Dallas, TexasAges 10–25 - NCT07547566Recruiting
TECAR Therapy vs. Cycling for Athletic Recovery
This study compares two recovery methods—TECAR therapy (a heating treatment) and cycling—to see which helps young athletes recover better after jumping exercises. The goal is to understand which approach reduces fatigue and helps athletes bounce back faster.
Córdoba, CórdobaAges 18 years+ - NCT06729190Recruiting
Electrical stimulation and biofeedback for children with muscle tightness
This trial tests if combining biofeedback (learning to control body signals) with mild electrical stimulation can help children ages 5 to 10 who have muscle tightness in their arms. It may improve arm movement and daily function.
GizaAges 5–10 - NCT05091112Recruiting
Study of nerves during low back surgery
This study looks at tiny nerves in the low back during planned lumbar spine surgery. It may help researchers better understand nerve pathways that contribute to low back pain and nerve-related symptoms.
Aberdeen, ScotlandAges 18 years+ - NCT05233605Recruiting
Study sedative effects on ongoing brain inflammation after severe COVID
This study looks at whether a specific ICU sedative (dexmedetomidine) affects long-term inflammation in the brain after severe COVID with ARDS and deep sedation. It uses PET and MRI scans and special tracers to understand persistent inflammation and why it may last.
ParisAges 18–74 - NCT06747741Recruiting
Stretching vs. physical therapy for restless leg syndrome in seniors
This study compares a special stretching technique (PNF) with standard physical therapy to see which better relieves restless leg syndrome symptoms in people aged 60 and older. It may help reduce the uncomfortable urge to move your legs at night.
IslamabadAges 60 years+ - NCT06746532RecruitingEarly Phase 1
Breast milk nose drops for brain injury in newborns
This trial tests whether giving fresh breast milk as nose drops can help newborns with brain injury from lack of oxygen. It aims to see if this simple treatment can improve brain recovery.
BudapestAges Up to 2 days - NCT06747728Recruiting
Bevacizumab before surgery for new high-grade brain tumors
This trial tests whether giving bevacizumab (a drug that blocks blood vessel growth) before surgery helps treat newly diagnosed high-grade gliomas. It may be an option for adults who have not had prior anti-angiogenic therapy.
Zhengzhou, HenanAges 18 years+ - NCT06747039Recruiting
Cannabis extract for fibromyalgia pain
This trial tests a cannabis extract called Avextra 10/10 for people with fibromyalgia who haven't gotten better with standard treatments. It aims to see if this option can help manage pain and other symptoms.
Milan, MilanoAges 18 years+ - NCT06746909Recruiting
Brain inflammation and imaging in older adults at risk for dementia
This study looks at how changes in the brain (like inflammation) relate to thinking and memory decline in older adults. It uses brain scans and computer tools to find early signs of dementia risk, with the goal of better preventing memory loss.
PisaAges 65–89 - NCT04934176Recruiting
3D study of smile reconstruction for facial paralysis
This study looks at how well “smile reconstruction” surgery works for people with facial paralysis, using 3D measurements that reflect patient experience and movement. You may be able to help test which nerve-connection approach leads to better smile outcomes.
Columbus, OhioAges 18–75 - NCT06016608Recruiting
Polyvascular disease imaging study
This study uses a special camera to take detailed pictures of artery blockages in people with heart disease, stroke, or mini-stroke. It may help doctors better understand how to treat multiple blocked arteries.
Harbin, HeilongjiangAges 18 years+ - NCT06359782RecruitingPhase 2
Testing C1-inhibitor for brain bleed after aneurysm
This trial tests a drug called C1-inhibitor (a protein that calms inflammation) given shortly after a bleeding stroke caused by an aneurysm. The goal is to see if it can reduce brain damage and improve recovery.
The Hague, South HollandAges 18 years+ - NCT06017973Recruiting
Imaging tests for possible non-convulsive status epilepticus
This trial uses advanced imaging scans (PET-MRI) to help doctors better understand and manage a type of seizure that doesn't cause convulsions. It may help improve diagnosis and treatment for people with this condition.
LeuvenAges 16 years+ - NCT06271187Recruiting
Brace Therapy for Hand Recovery After Stroke
This study tests whether a custom brace (dynamic orthosis) combined with therapy can improve hand movement in people who had a stroke at least 3 months ago. It is designed for those whose arm has some recovery but still needs help with hand opening and grasping.
TainanAges 20–80 - NCT07542028Recruiting
Pain Relief Methods for Kidney Transplant Surgery
This study compares different pain management techniques during kidney transplant surgery. It aims to find the most effective way to control pain after your operation.
Altındağ, AnkaraAges 18–65 - NCT06459388Recruiting
Balance training methods for stroke recovery
This study compares two types of physical therapy exercises to help stroke survivors improve balance and walking. One method uses arm and leg movements, while the other focuses on the pelvis area.
Lahore, Punjab ProvinceAges 40–65 - NCT06407830Recruiting
Walking therapy with and without muscle stimulation for stroke recovery
This study tests whether adding electrical muscle stimulation to a walking and movement program helps stroke survivors walk better, become more independent, and improve their quality of life.
Lahore, Punjab ProvinceAges 45–65
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,941 recruiting neurology studies from the U.S. registry right now, out of 18,432 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.