Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,420 recruiting studies in this area right now.
By phase
- Not applicable9,752
- Phase 2783
- Phase 1576
- Phase 3536
- Phase 4343
- Phase 1/Phase 2307
- Phase 2/Phase 3123
Top conditions
- Stroke844
- Parkinson Disease426
- Alzheimer Disease342
- Multiple Sclerosis341
- Dementia227
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea156
- Insomnia155
- Spinal Cord Injuries153
- Traumatic Brain Injury150
- Sarcopenia149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment130
- Migraine113
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California679
- Massachusetts300
- New York292
- Florida275
- Texas266
- Maryland246
- Arizona213
- Alabama210
- Illinois187
- Pennsylvania178
Recruiting studies12,418 total
- NCT03678389Recruiting
Check feasibility of a coil for pituitary surgery imaging
This trial tests whether a special coil can be placed during pituitary tumor surgery to improve imaging while the surgeon is operating. It may help surgeons see the pituitary area in real time during a transsphenoidal (through the nose) operation.
Bethesda, MarylandAges 18–85 - NCT03678194Recruiting
Smartphone app tool for doctors managing daily depression
This trial tests a smartphone app that helps doctors manage depression in everyday life. It may help improve how care is tracked and adjusted soon after starting antidepressant treatment.
BordeauxAges 18–65 - NCT03680872Recruiting
Brain-to-nerve study to improve hand movement after spinal injury
This trial tests a “neural bypass” approach to help restore hand movement and feeling in people with tetraplegia from a spinal cord injury. You would have repeated visits for brain/nerve testing and may receive study procedures to see if function improves.
Manhasset, New YorkAges 22–65 - NCT03684109Recruiting
MRI scans to study brain tumors using molecular imaging
This study uses special MRI scans to better “characterize” (study) gliomas, a type of brain tumor, using information from your brain tissue. You may be eligible if you’re an adult with a suspected or confirmed glioma and you already need a biopsy or surgery.
Miami, FloridaAges 18 years+ - NCT03694626Recruiting
Test a light-response study to measure and track light sensitivity
This study aims to objectively measure how your pupils respond to light and how your eye muscles react using recording tests. It may help confirm the cause of light sensitivity (especially after a brain injury) and better track how it responds to care.
Iowa City, IowaAges 18–80 - NCT03696680RecruitingPhase 2
Stereotactic radiation for brain metastases that recently bled
This trial tests a precise type of radiation aimed at brain metastases that show signs of recent bleeding. It aims to control the tumors while reducing risks, especially compared with the usual approach for patients who have bleeding signals in the brain lesions.
AvranchesAges 18 years+ - NCT03698149Recruiting
Brain-signal training for hand and speech control after disability
This study tests whether recording brain signals can help people regain better control of movements in the arms and help with speech. It may be an option for people with significant disability from certain nerve and brain conditions who can safely take part in brain-monitoring procedures.
San Francisco, CaliforniaAges 21 years+ - NCT03702309Recruiting
Banking and testing blood samples to study cancer
This study collects blood samples to “test and store” (bank) information that may help doctors understand cancer in the future. You might be able to join if you’re an adult with confirmed cancer or a higher-than-usual risk for cancer.
Toronto, OntarioAges 18 years+ - NCT03702907Recruiting
Study of aging and a brain sample bank
This study follows adults as they age and may collect biological samples for future research. It could help researchers understand early and late changes related to aging and brain health.
Washington D.C., District of ColumbiaAges 45 years+ - NCT03710902Recruiting
Mobile coaching to lower heart risk after stroke
This trial tests whether a mobile technology program can help people manage risk factors like high blood pressure after an ischemic stroke or a “mini-stroke” (TIA). It may help lower future cardiovascular risks by improving day-to-day control of these conditions.
HämeenlinnaAges 40 years+ - NCT03708900RecruitingPhase 2
Osilodrostat study for children with Cushing’s syndrome
This Phase 2 study tests how osilodrostat works in children and teens with Cushing’s syndrome—what the drug does in the body, how it affects hormones, and how safely it’s tolerated. It may help families who cannot have immediate surgery or whose surgery has already failed or is still pending.
San Francisco, CaliforniaAges 2–17 - NCT03713268Recruiting
Using a scan to guide eye surgery in real time
This trial tests whether a special eye scan (OCT) can help guide eye surgery during the operation. It may improve how surgeons see and target the exact eye structures they need to treat.
Durham, North CarolinaAges 4 weeks+ - NCT03715517Recruiting
Spinal anesthesia to improve recovery after liver surgery
This trial studies whether using spinal/epidural anesthesia during liver tumor removal surgery can help people recover better and with less pain. It compares this approach to standard general anesthesia care to see if recovery is smoother.
Winnipeg, ManitobaAges 18 years+ - NCT03717844Recruiting
Registry for adults with plasma cell disorders
This study is a registry that collects information about adults with plasma cell disorders (conditions involving abnormal antibody-producing cells). It may help researchers understand these diseases better and improve future care by tracking patients over time.
Chapel Hill, North CarolinaAges 18 years+ - NCT03718936Recruiting
Study of genetic ADNP conditions in children and adults
This study looks at how people with certain disease-causing changes in the ADNP gene function using medical, genetic, and thinking/behavior assessments. It may help doctors better understand the condition and tailor support for families.
New York, New YorkAges 2 years+ - NCT03718923Recruiting
Study for people with FOXP1 gene changes
This study looks at how people with FOXP1-related neurodevelopmental conditions work and how they’re affected, using genetic, medical, and thinking/learning tests. It may help researchers better understand the condition and improve future care.
New York, New YorkAges 2 years+ - NCT03721068RecruitingPhase 1
CAR T-cell treatment for hard-to-treat childhood tumors
This Phase 1 study tests an experimental CAR T-cell treatment that targets GD2, with added immune-boosting and safety features, for children with relapsed or refractory neuroblastoma or osteosarcoma. It’s designed to see if the treatment is safe and can shrink these cancers when standard therapy hasn’t worked.
Atlanta, GeorgiaAges 1.5 years+ - NCT03720522Recruiting
Study brain-heart signals in acute stroke using MRI
This study looks at how the brain and heart interact right after an acute ischemic stroke. It may help doctors better understand what happens in the first hours of stroke and improve monitoring or future treatments.
Bern, Canton of BernAges 18–86 - NCT03725956Recruiting
Sleep study before and after nasal polyp surgery
This study uses a sleep test to look at breathing and sleep patterns in people with nasal polyps who need surgery because medicine didn’t help. It may help doctors understand how nasal polyps affect sleep and how surgery changes those sleep measurements.
LilleAges 18 years+ - NCT03726047Recruiting
Exercise and training to improve walking after chronic stroke
This study tests whether exercise plus motor learning training can improve walking and movement after a stroke that happened more than 6 months ago. You may be a good candidate if you can walk on your own and your stroke-related brain injury is not mainly in the cerebellum.
Newark, DelawareAges 18–85 - NCT03731000Recruiting
Testing a glue-like treatment for abnormal brain vessel leaks in children
This trial studies a device that delivers a special “embolic” material (often described as glue) to treat a type of abnormal connection in the brain’s blood vessels (dAVF). It may help by blocking the leaking or risky blood flow, and it will be compared against how doctors handle eligible cases with other embolic materials.
New York, New YorkAges Up to 21 years - NCT03736382Recruiting
Study how mild low-oxygen affects sleep apnea and blood pressure
This trial studies whether mild, controlled low oxygen during sleep can change sleep apnea symptoms and related blood pressure issues. It mainly looks at people with newly diagnosed, untreated sleep apnea and early high blood pressure.
Detroit, MichiganAges 18–60 - NCT03737786Recruiting
Sedation with collateral support for stroke clot removal
This trial tests a specific sedation approach, along with support during the procedure, for people having emergency clot removal (mechanical thrombectomy) for a certain type of acute ischemic stroke. It may help make the procedure safer and more effective by improving how patients are managed during endovascular treatment.
Los Angeles, CaliforniaAges 18–110 - NCT03738072Recruiting
Test of brain electrical stimulation to plan epilepsy surgery
This study looks at how using a mild electrical stimulation in the brain may help doctors plan surgery for people with drug-resistant focal (partial) epilepsy. It happens during a hospital procedure to map the seizure areas (SEEG), so it may help improve where surgery targets.
ToulouseAges 12–65
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,420 recruiting neurology studies from the U.S. registry right now, out of 19,378 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.