Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,413 recruiting studies in this area right now.
By phase
- Not applicable9,750
- Phase 2784
- Phase 1574
- Phase 3535
- Phase 4342
- Phase 1/Phase 2305
- Phase 2/Phase 3123
Top conditions
- Stroke845
- Parkinson Disease426
- Multiple Sclerosis343
- Alzheimer Disease341
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea155
- Spinal Cord Injuries154
- Insomnia153
- Sarcopenia149
- Traumatic Brain Injury149
- Acute Ischemic Stroke139
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Pain Management114
- Migraine112
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing94
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California678
- Massachusetts300
- New York291
- Florida275
- Texas266
- Maryland245
- Arizona213
- Alabama210
- Illinois188
- Pennsylvania178
Recruiting studies12,411 total
- NCT03946930Recruiting
Study of memory decline in Alzheimer’s disease
This trial studies people diagnosed with Alzheimer’s disease who are at a moderate stage of decline. It likely involves cognitive (memory/thinking) testing and care-partner input to help track changes over time.
Hong KongAges 65–92 - NCT03948373Recruiting
Study of sleep apnea patients with normal blood pressure
This study is looking at a specific sleep-related condition (obstructive sleep apnea) in adults whose blood pressure is not high, and how their blood pressure rhythm changes over the day. If you have sleep apnea, participating could help researchers understand patterns that may affect long-term health.
LleidaAges 18–100 - NCT03953768Recruiting
Testing a new vagus nerve stimulator for gut and immune health
This study looks at what happens to your immune system and stomach/gut function after getting a vagus nerve stimulator (VNS) for the first time for epilepsy. It may help doctors understand whether the device benefits more than seizures.
Louisville, KentuckyAges birth–60 years - NCT03952637RecruitingPhase 1/Phase 2
Gene therapy for GM1 disease with IV delivery
This early-stage study tests an IV gene therapy that delivers a working copy of an enzyme gene to help the body make beta-galactosidase in GM1 gangliosidosis. It may help slow or improve disease symptoms and looks closely at safety and how well the treatment works.
Bethesda, MarylandAges 6 months–12 years - NCT03956446Recruiting
Testing blood antibody patterns in tick-borne brain and Lyme illness
This study looks at blood antibody test results in adults who may have tick-borne encephalitis and also signs of Lyme disease. It may help researchers understand how these infections relate and which lab patterns fit different illnesses.
LjubljanaAges 18 years+ - NCT03957343Recruiting
Parkwood Pacing and Planning app for concussion recovery
This study tests a smartphone or tablet app (the Parkwood Pacing and Planning app) that may help people after a mild concussion manage recovery. You may be able to join if you’re an adult, can use the app device, and have a confirmed mild concussion.
London, OntarioAges 18 years+ - NCT03968393RecruitingPhase 4
Blood thinner to prevent stroke after stress-related irregular heartbeats
This trial tests whether taking a blood thinner can lower the risk of stroke in people who had atrial fibrillation (an irregular heartbeat) that happened temporarily around a stressful illness or surgery. It looks especially at people at higher risk for stroke after that episode.
Los Angeles, CaliforniaAges 55 years+ - NCT03965299Recruiting
Gentle nerve stimulation for new spinal cord injury recovery
This study tests whether stimulation through the skin of the tibial nerve can help people with a new spinal cord injury. It may help improve bladder-related symptoms or nerve signaling after injury, compared with standard care.
Zurich, Canton of ZurichAges 18 years+ - NCT03974750Recruiting
Robotics training for arm skills after stroke
This study tests whether a robotic training program can help people relearn arm and hand skills after a stroke. It also includes healthy volunteers to compare learning and movement changes.
Yvoir, NamurAges 18–90 - NCT03979235Recruiting
Rehab effectiveness programs for people after stroke
This trial is testing rehabilitation programs by studying how well they work for people with movement problems after a stroke. You may be able to join if you can complete the rehab assessment and follow testing instructions.
BeijingAges 18–80 - NCT03980457Recruiting
Exoskeleton walking therapy for stroke recovery
This trial studies whether assisted walking training with an exoskeleton can improve recovery after stroke, especially for walking and daily function. You may be offered therapy once you are medically stable, able to stand, and able to participate safely.
Oklahoma City, OklahomaAges 18–90 - NCT03981003Recruiting
Blood tests to track brain and nerve changes in MS
This study measures blood markers (from a serum blood sample) to see how nerve and brain changes relate to MS disease activity and disability over time. It may help researchers better monitor MS, especially in people followed in the OFSEP program.
AmiensAges 15 years+ - NCT03981276Recruiting
Study aims to understand inherited walking stiffness disorders
This study looks at the causes and biology (“biomarkers”) of hereditary spastic paraplegias and related conditions. You may join as someone with the condition, a family member without symptoms, or a healthy person, to help researchers understand what’s happening in the nervous system.
InnsbruckAges Any age - NCT03981575Recruiting
Biomarker and health marker study in myotonic dystrophy type 1
This study measures physical and lab “health markers” in people with myotonic dystrophy type 1 (DM1) to better understand how the disease changes over time. Some participants may also have a muscle biopsy to study tissue differences.
La Jolla, CaliforniaAges 18–70 - NCT03984656RecruitingPhase 3
Nerve-block pain control during lung fluid drainage in ICU
This trial tests whether a specific pain-relief nerve block (given with numbing medicine) can make pleural drainage in the ICU more comfortable. It may help reduce pain during the procedure for people who are awake and breathing on their own.
AmiensAges 18 years+ - NCT03984643Recruiting
Testing computer planning for DBS surgery in essential tremor
This study looks at computer “planning algorithms” for DBS surgery in people with essential tremor whose medication hasn’t helped enough. It may help doctors program the DBS system more accurately for better tremor control.
Minneapolis, MinnesotaAges 21 years+ - NCT03987633Recruiting
Study links health records and samples to understand health gaps
This study asks people affected by a specific illness (or their family member) to share saliva (and sometimes blood) and answer health and quality-of-life questions. The goal is to better understand and reduce health inequality by matching new information with medical records.
Wolverhampton, West MidlandsAges 6 years+ - NCT03988764Recruiting
Checking monogenic diabetes wrongly labeled as type 1
This trial looks at people who were diagnosed with diabetes before age 25 as either type 1 or “not sure which type.” It may help confirm whether the cause is genetic (monogenic) rather than type 1, which can change treatment choices.
Montreal, QuebecAges 1 day–25 years - NCT03990909Recruiting
BCAA supplements to help improve sleep
This pilot study tests whether taking BCAA supplements can improve sleep problems. You may be able to join if you’re a veteran with sleep issues and can do the study by phone.
Portland, OregonAges 18–89 - NCT03990558Recruiting
Testing ways to improve waking after a brain bleed
This trial studies treatments to help people regain consciousness after an intracerebral hemorrhage (a bleeding stroke inside the brain). It focuses on adults who are unresponsive to commands within 48 hours, likely from certain bleeding locations, and who meet specific safety and language requirements.
Miami, FloridaAges 18 years+ - NCT03992625Recruiting
Deep brain stimulation study for Parkinson’s, tremor, or dystonia
This trial studies outcomes after deep brain stimulation (a treatment that uses implanted electrodes) for people with Parkinson’s disease, essential tremor, or dystonia. It may help doctors understand who benefits most and how outcomes change after treatment.
St Louis, MissouriAges Any age - NCT03993262RecruitingPhase 2
Bortezomib for severe autoimmune encephalitis after rituximab
This Phase 2 study tests whether bortezomib can improve outcomes and safety in adults with severe autoimmune encephalitis. It focuses on people whose condition is confirmed by brain-related autoantibodies and who have already received rituximab.
München, BavariaAges 18 years+ - NCT03998852RecruitingPhase 3
PET study of brain chemical changes in stroke apathy
This Phase 3 trial uses special brain scans (PET) to understand what brain chemical systems are involved in apathy after stroke. Your results may help researchers better understand the cause of apathy and guide future treatments.
BordeauxAges 18–75 - NCT03996824Recruiting
Gene therapy study for certain vestibular schwannoma surgeries
This trial tests delivering gene therapy into the inner-ear hearing balance nerve cells during surgery for vestibular schwannoma. It may help by improving how the inner ear functions after tumor removal, but you must meet several specific surgery and safety requirements.
Le Kremlin-Bicêtre, Île-de-France RegionAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,413 recruiting neurology studies from the U.S. registry right now, out of 19,419 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.