Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,941 recruiting studies in this area right now.
By phase
- Not applicable9,343
- Phase 2764
- Phase 1557
- Phase 3513
- Phase 4339
- Phase 1/Phase 2300
- Phase 2/Phase 3125
Top conditions
- Stroke796
- Parkinson Disease395
- Alzheimer Disease338
- Multiple Sclerosis329
- Dementia226
- Epilepsy193
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke139
- Sarcopenia135
- Mild Cognitive Impairment127
- Cerebral Palsy119
- Pain Management114
- Migraine107
- Fibromyalgia104
Leading sponsors
- Beijing Tiantan Hospital124
- Assistance Publique - Hôpitaux de Paris109
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California659
- Massachusetts305
- New York294
- Florida271
- Texas266
- Maryland248
- Alabama207
- Arizona207
- Illinois181
- Pennsylvania176
Recruiting studies11,941 total
- NCT07518069Recruiting
Understanding Genes and Biology in Menière's Disease
This research study investigates the genetic and biological factors that cause Menière's disease—a condition affecting the inner ear that causes dizziness, hearing loss, and ear fullness. By studying these factors, researchers hope to better understand why some patients experience different symptoms and potentially improve future treatments.
Milan, ItalyAges 18 years+ - NCT07518927Enrolling by invitation
Brain Mapping Study Using Ultrasound and Implanted Electrodes
This research study uses focused ultrasound waves combined with brain electrodes (already implanted for your epilepsy or psychiatric treatment) to map how your brain responds. The goal is to better understand brain function and potentially improve future treatments.
Philadelphia, PennsylvaniaAges 21–75 - NCT07523113Recruiting
Brain Fog Treatment for ME/CFS Using Cognitive Training
This study tests whether a computerized cognitive training program combined with a mild electrical nerve stimulation device (worn on the ear) can help improve thinking and memory problems in people with ME/CFS. The goal is to see if this approach helps with brain fog and daily functioning.
Birmingham, AlabamaAges 18 years+ - NCT07524231Recruiting
Laughter Yoga Effects on Health and Well-being
This study tests whether laughter yoga—guided exercises that combine laughter with breathing—can improve health outcomes. Researchers will measure how it affects participants' physical and mental well-being over time.
ElâzığAges 18 years+ - NCT07517354Recruiting
Understanding Moyamoya Disease Risk in Families
This study investigates moyamoya disease, a rare condition where blood vessels in the brain narrow over time. Researchers want to identify genetic and early warning signs by studying people diagnosed with the disease, their blood relatives, and healthy volunteers.
Beijing, Beijing MunicipalityAges Any age - NCT07520032Recruiting
Shockwave therapy for arm function after stroke
This trial tests whether a non-invasive shockwave treatment can help improve arm movement and strength in people who had their first stroke within the past 6 months. The goal is to see if this therapy reduces stiffness and helps patients regain better use of their arm.
Ajman, Ajman EmirateAges 18–65 - NCT07517185RecruitingPhase 2
Early aggressive treatment for relapsing multiple sclerosis
This trial tests whether treating relapsing multiple sclerosis (RRMS) aggressively and early with a specific medication can slow disease progression. You may qualify if you were recently diagnosed, have had recent disease activity, and are willing to take a strong immunosuppressive drug with regular MRI monitoring.
FalunAges 18–50 - NCT07520214Enrolling by invitationEarly Phase 1
Cancer vaccine to prevent glioblastoma recurrence
This early-stage study tests a personalized cancer vaccine designed to prevent glioblastoma (a serious brain tumor) from coming back after surgery and standard treatment. The vaccine aims to train your immune system to recognize and attack any remaining cancer cells.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07523503Recruiting
One-sided vs. both-sides arm training after stroke
This study compares two ways of doing hand and arm exercises after stroke: practicing with just your weak arm, or practicing with both arms together. The goal is to see which approach helps you regain better movement, strength, and hand coordination.
Kot AdduAges 40–75 - NCT07523438Recruiting
Nasal Medication to Reduce Agitation After Eye Surgery in Young Children
This study tests whether a medication given through the nose (dexmedetomidine) can help children stay calmer when waking up from eye-muscle surgery. Some children get very agitated or upset when coming out of anesthesia, and this medication might help prevent that.
AlexandriaAges 3–6 - NCT06748196Recruiting
Physical therapist awareness of sensory integration for cerebral palsy
This study wants to find out how much physical therapists know about a therapy called sensory integration for children with cerebral palsy. If you are a physical therapist working in Khyber Pakhtunkhwa, Pakistan, your answers can help improve care for these children.
Lahore, Punjab ProvinceAges Any age - NCT06705153Recruiting
Laughter yoga for irritable bowel syndrome
This study tests whether laughter yoga can help reduce IBS symptoms like belly pain and bloating, and also improve mood, sleep, and overall quality of life. You would join video calls where you practice special laughing exercises (no jokes needed) and then answer questionnaires.
Erzurum, YakutiyeAges 18–90 - NCT06732713Recruiting
Swiss ball vs. Frenkel exercises for Down syndrome
This trial compares using a Swiss ball versus Frenkel exercises to improve balance and coordination in children with Down syndrome. It may help children who can stand and walk on their own.
Lahore, Punjab ProvinceAges 8–13 - NCT06758115Recruiting
Brain and Muscle Study for Teens with Scoliosis
This study looks at how the brain and muscles work together in teens with spinal curves (scoliosis). It uses skin sensors and brain wave tests to understand muscle control, which may help improve treatments.
HangzhouAges 10–18 - NCT06757062Recruiting
Red tape for gamers with carpal tunnel symptoms
This study tests if red kinesiology tape can help reduce symptoms like numbness, tingling, and pain in the hands and wrists of esports players who play over 5 hours a week. If you have carpal tunnel-like symptoms, this trial might help you find a non-surgical option.
Las Vegas, NevadaAges 18 years+ - NCT06756633Recruiting
Breathing and movement study for neuromuscular disease
This study looks at breathing, chest and belly movement, and exercise ability in people with Duchenne Muscular Dystrophy or Spinal Muscular Atrophy, as well as healthy people. The goal is to compare these functions to help understand how these diseases affect the body.
Ankara, ÇankayaAges 5–15 - NCT06301412RecruitingPhase 3
Cooling plus clot removal for acute stroke
This trial tests whether cooling the body down (hypothermia) combined with a clot removal procedure (thrombectomy) helps people recover better from a large-artery stroke. You may be eligible if you have a moderate-to-severe stroke and can be treated within 24 hours of when you were last seen well.
Freiburg im BreisgauAges 18 years+ - NCT05801380Recruiting
Tracking how well a medicine works in Alzheimer’s patients
This study looks at how effective a treatment is in people newly diagnosed with mild to moderate Alzheimer’s disease. It also involves health and medication history checks and likely stool (fecal) sample collection to monitor effects.
Manila, National Capital RegionAges 65 years+ - NCT06579677Recruiting
Watching small blood vessels in the brain over time
This study watches how small blood vessels in the brain change over time. It may help doctors understand brain health as people age.
Beijing, Beijing MunicipalityAges 50–75 - NCT06758648Recruiting
Eye blood vessels in Fabry disease
This study looks at the tiny blood vessels in the eyes of people with Fabry disease using a special camera. It may help doctors understand how the disease affects the eyes over time.
München, BavariaAges 18 years+ - NCT04142866Recruiting
Brain stimulation plus language practice for chronic aphasia
This study tests whether mild brain stimulation (tDCS) combined with language exercises can improve communication after a stroke. It also includes healthy volunteers to help compare brain and language task results.
New York, New YorkAges 21–80 - NCT07511049RecruitingPhase 2
Brincidofovir for PML brain infection
This pilot study tests an IV medicine called brincidofovir for people with PML, a serious brain infection. The goal is to see if it can stop the virus from causing more damage.
Bethesda, MarylandAges 18–99 - NCT07508410Recruiting
Mulligan vs Myofascial Release for Neck-Related Headaches
This study compares two hands-on therapy techniques—Mulligan mobilization and myofascial release—to see which works better for headaches that start from the neck. If you have neck pain on one side and headaches that get worse with movement, this trial may help you find relief.
KonyaAges 18–65 - NCT07511556RecruitingPhase 1/Phase 2
Study of UX016 for people with GNE myopathy
This study tests a new medicine called UX016 for people with GNE myopathy, a rare genetic muscle disease that causes weakness in the hands and legs. The trial aims to see if the medicine is safe and whether it can help improve muscle strength. It is the first time this medicine is being tested in humans.
Orange, CaliforniaAges 18–55
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,941 recruiting neurology studies from the U.S. registry right now, out of 18,432 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.