Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,941 recruiting studies in this area right now.
By phase
- Not applicable9,343
- Phase 2764
- Phase 1557
- Phase 3513
- Phase 4339
- Phase 1/Phase 2300
- Phase 2/Phase 3125
Top conditions
- Stroke796
- Parkinson Disease395
- Alzheimer Disease338
- Multiple Sclerosis329
- Dementia226
- Epilepsy193
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke139
- Sarcopenia135
- Mild Cognitive Impairment127
- Cerebral Palsy119
- Pain Management114
- Migraine107
- Fibromyalgia104
Leading sponsors
- Beijing Tiantan Hospital124
- Assistance Publique - Hôpitaux de Paris109
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California659
- Massachusetts305
- New York294
- Florida271
- Texas266
- Maryland248
- Alabama207
- Arizona207
- Illinois181
- Pennsylvania176
Recruiting studies11,941 total
- NCT07513441RecruitingPhase 1
Testing Lu AF28996 for Parkinson's disease motor fluctuations
This early-stage trial tests a new medication called Lu AF28996 in Chinese patients with Parkinson's disease who experience predictable on-off episodes (times when medication works well versus poorly). The study aims to see if this drug can help reduce those difficult off periods.
Beijing, Beijing MunicipalityAges 35–85 - NCT07511556RecruitingPhase 1/Phase 2
Study of UX016 for people with GNE myopathy
This study tests a new medicine called UX016 for people with GNE myopathy, a rare genetic muscle disease that causes weakness in the hands and legs. The trial aims to see if the medicine is safe and whether it can help improve muscle strength. It is the first time this medicine is being tested in humans.
Orange, CaliforniaAges 18–55 - NCT07514858RecruitingPhase 2
Lu AF28996 for Parkinson's Disease Motor Fluctuations
This trial tests a new medication called Lu AF28996 to help reduce the periods when Parkinson's symptoms worsen throughout the day (called 'OFF times'). If you have motor fluctuations that are predictable and affecting your daily life, this study might help you experience fewer of these difficult periods.
Farmington Hills, MichiganAges 40–85 - NCT04672733Recruiting
Switch from IVIg to Hizentra for CIDP nerve inflammation
This study tests Hizentra® as an alternative to IV immunoglobulin (IVIg) for adults with CIDP, a condition where the immune system damages the nerves. You may be able to switch to Hizentra if your current IVIg treatment is keeping your CIDP stable and you can switch safely.
AmiensAges 18 years+ - NCT07509671Recruiting
Can a diet help painful diabetic nerve pain?
This study tests whether a special diet can help reduce pain caused by nerve damage from Type 2 diabetes or prediabetes. You may qualify if you have painful diabetic neuropathy and are looking for a non-medication approach.
Hendersonville, North CarolinaAges 18 years+ - NCT07512362RecruitingPhase 2
Stem cells and antibodies for early Alzheimer's disease
This study tests whether human stem cells, combined with your existing Alzheimer's medication (Leqembi or Kisunla), can help slow memory loss and improve daily functioning in people with mild cognitive impairment or early Alzheimer's. You would receive a stem cell infusion as an add-on to your current treatment.
Miami, FloridaAges 55–90 - NCT07509645RecruitingPhase 3
Testing a new drug with clot removal for severe back-of-the-brain stroke
This trial checks if adding an interleukin-6 receptor inhibitor (a drug that reduces inflammation) to standard emergency clot removal can improve recovery for people with a severe stroke affecting the back part of the brain (posterior circulation). It is for patients who need urgent treatment within 24 hours of symptom onset.
Huaibei, AnhuiAges 18 years+ - NCT07512830Recruiting
Using Hypnosis to Help During Heart Ultrasound
This study tests whether hypnosis (guided relaxation) can help patients feel more comfortable and less anxious during a heart ultrasound procedure that looks at the heart from inside the throat. The goal is to see if it reduces discomfort and the need for sedating medications.
Paris, Île-de-France RegionAges 18 years+ - NCT07509177Recruiting
Infrared light therapy for stress in epilepsy
This trial tests if infrared light therapy can help reduce stress in people with epilepsy. You would wear a ring to track your sleep and activity, and attend 45 light therapy sessions over several months.
North Miami, FloridaAges 18 years+ - NCT07509125Recruiting
Ultra-high resolution PET brain scans for aging, dementia, and psychosis
This study uses a new ultra-high resolution PET scanner to look at brain changes in healthy aging, dementia, ALS, movement disorders, and psychosis. It aims to better understand these conditions and improve imaging techniques.
Leuven, Vlaams-BrabantAges 18–90 - NCT07508631Recruiting
Friedreich Ataxia Nerve Ultrasound Study
This trial uses an ultrasound to look at nerves in people with Friedreich's Ataxia. It may help doctors better understand how the condition affects the nervous system.
Nice, Alpes MaritimesAges 18–70 - NCT07510633Recruiting
Mobile brain/body imaging for robotic gait rehab after stroke
This trial uses a mobile brain and body imaging system to help improve walking with a robotic exoskeleton in people who have had a stroke. It could help you walk better during overground gait training.
Costa Masnaga, LeccoAges 18 years+ - NCT07516028Recruiting
How Your Brain Responds to Low Oxygen Levels
This study looks at how your brain's nerve signals change when exposed to moderate low-oxygen conditions. Researchers will use brain stimulation and imaging to understand these changes, which could help future treatments for brain and spinal cord conditions.
Loos, Hauts-de-FranceAges 18–65 - NCT07513844Recruiting
Ultrasound Treatment for Huntington's Disease Movement Symptoms
This trial tests a new focused ultrasound technique aimed at reducing involuntary movements (chorea) in people with Huntington's disease. The treatment targets a specific brain region and may help improve movement control and quality of life.
Fuzhou, FujianAges 18–75 - NCT07510854Recruiting
Sentence prediction in language disorder study
This study tests how children with developmental language disorder predict sentences. It compares their performance to typical children to better understand language processing.
Omaha, NebraskaAges 5–7 - NCT07511413Recruiting
Monitoring health in head, neck, lung & rectal cancer
This trial is studying how a monitoring method (bioimpedance) works for people with head and neck, lung, or rectal cancer who are about to start standard treatment. It may help doctors track your health better during therapy.
Candiolo, Torino (TO)Ages 18 years+ - NCT07509788Recruiting
Studying hearing with two ears in kids with cochlear implants
This trial looks at how hearing with both ears helps children with cochlear implants listen more easily and think better. It compares kids with implants to those with normal hearing.
Guangzhou, GuangdongAges 6–18 - NCT07511959Enrolling by invitation
Blood-derived treatment for chronic jaw pain
This trial tests whether a treatment made from your own blood (platelet-rich plasma exosomes) can help relieve long-term jaw joint pain and improve function. If you qualify, you would receive injections directly into your jaw area.
WroclawAges 18 years+ - NCT07516119Recruiting
Predicting Alzheimer's Risk Before Memory Loss Occurs
This study identifies people at high risk for Alzheimer's disease before symptoms develop, using genetics and digital tools to track brain health over time. If you qualify, you'll help researchers understand who will develop cognitive decline and potentially enable earlier interventions.
San Diego, CaliforniaAges 55 years+ - NCT07514923RecruitingEarly Phase 1
ALT001 safety study for cerebellar multiple system atrophy
This early-stage trial tests a new biologic treatment called ALT001 in people with multiple system atrophy-cerebellar type (MSA-C), a rare neurological condition affecting balance and coordination. The study focuses on whether ALT001 is safe and whether it shows early signs of helping slow disease progression.
Beijing, Beijing MunicipalityAges 30–75 - NCT07510607RecruitingPhase 2
Metabolic imaging study for multiple sclerosis
This study tests a new imaging method using a special substance called hyperpolarized 13C pyruvate to see how it can help understand multiple sclerosis. You may join if you have relapsing-remitting MS, have not used disease-modifying treatments in the past two years, and are planning to start anti-CD20 therapy.
San Francisco, CaliforniaAges 18 years+ - NCT07511933Recruiting
New PET scan to detect tumor regrowth vs. scar tissue in brain
This study tests a new type of PET scan (a special imaging test) that uses a radioactive tracer to help doctors tell the difference between scar tissue from past radiation and cancer that has come back in the brain. This could help avoid unnecessary surgery or additional treatment.
AmsterdamAges Any age - NCT07509190Recruiting
Helping patients learn about epilepsy surgery
This study aims to improve access to epilepsy surgery by educating patients about social factors that affect health. It includes surveys and focus groups for people with epilepsy who have undergone surgery evaluation at Cleveland Clinic.
Cleveland, OhioAges 18 years+ - NCT07513077Recruiting
Hearing Loss Prevention Program for Primary School Children
This study tests whether a hearing protection education program called HoorToren helps 11–12 year old children in Dutch schools prevent noise-induced hearing loss. The program teaches kids about protecting their ears from loud sounds.
RotterdamAges Any age
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,941 recruiting neurology studies from the U.S. registry right now, out of 18,432 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.