Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,934 recruiting studies in this area right now.
By phase
- Not applicable9,337
- Phase 2764
- Phase 1555
- Phase 3514
- Phase 4340
- Phase 1/Phase 2299
- Phase 2/Phase 3125
Top conditions
- Stroke797
- Parkinson Disease395
- Alzheimer Disease337
- Multiple Sclerosis330
- Dementia224
- Epilepsy192
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke139
- Sarcopenia135
- Mild Cognitive Impairment126
- Cerebral Palsy119
- Pain Management113
- Migraine107
- Fibromyalgia105
Leading sponsors
- Beijing Tiantan Hospital124
- Assistance Publique - Hôpitaux de Paris109
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California655
- Massachusetts304
- New York295
- Florida267
- Texas267
- Maryland248
- Arizona209
- Alabama205
- Illinois183
- Pennsylvania175
Recruiting studies11,934 total
- NCT05741151Recruiting
Testing a nerve target in Parkinson’s disease
This trial is studying the “superior cervical ganglion” as a possible treatment approach for Parkinson’s disease. It may help people whose symptoms are truly caused by Parkinson’s, not by another condition.
RomeAges 30–80 - NCT05752656Recruiting
Tracking outcomes after deep brain stimulation for Parkinson’s
This study follows people with Parkinson’s disease to see how their thinking, behavior, and movement change over time after deep brain stimulation. It may help doctors better understand what to expect from this treatment.
RomeAges 18 years+ - NCT05740605Recruiting
Testing an at-home therapy program for bilateral cerebral palsy
This trial tests an at-home intervention (called HABIT-ILE) for children with bilateral cerebral palsy, delivered over two weeks. It aims to see whether home-based therapy and assessments help children function better and whether families can follow the program.
BrusselsAges 5–18 - NCT05755451Recruiting
Study of the natural course of spinal muscular atrophy
This study observes how spinal muscular atrophy changes over time without giving an investigational treatment. It may help researchers learn what to expect in the disease and improve future care.
GenovaAges Any age - NCT05734378Recruiting
Study aims to predict outcomes in small blood vessel brain disease
This trial is looking at how brain “small blood vessel disease” changes over time and what outcomes to expect. If you have certain symptoms or scan findings from this condition, your care team may compare your prognosis to help guide future treatment planning.
BernAges 16 years+ - NCT04032379Recruiting
Study biomarkers to predict outcomes in idiopathic intracranial hypertension
This study looks at body measurements (“biomarkers”) to help doctors diagnose idiopathic intracranial hypertension (IIH) and predict how it may go over time. If you’re an adult with a doctor’s concern for IIH, you may be asked to provide health information and possibly samples for testing.
Copenhagen, GlostrupAges 18 years+ - NCT05643092Recruiting
Testing scans and biomarkers for CAR T neurotoxicity risk
This study uses blood tests and brain imaging to better understand and predict nerve-system side effects that can happen after CAR T-cell treatment. It may help doctors spot people at higher risk sooner and guide safer care.
Shijiazhuang, HebeiAges 18–80 - NCT05044208Recruiting
Test heart ultrasound and monitoring clues for atrial fibrillation
This study looks at heart ultrasound pictures and heart-rhythm recordings to predict who may develop atrial fibrillation (AF) after a stroke or TIA. If you qualify, your results may help doctors better spot people at higher risk earlier.
TullnAges 18 years+ - NCT05752682Recruiting
Check care for fainting or falls in adults over 40
This trial tests a “global” approach to assessing episodes of fainting or falling in people age 40 and older. It may help doctors find the right cause and safer next steps after an episode.
Milan, MIAges 40 years+ - NCT05765981RecruitingEarly Phase 1
Testing a gene therapy for AADC deficiency in young children
This early-stage trial tests VGN-R09b, a gene therapy, given to children with AADC deficiency who are not doing well on standard medicines. It aims to improve symptoms and quality of life by addressing the underlying cause of AADC deficiency.
Shanghai, No. 1678, Dongfang Road, Pudong New Area, ShanghaiAges 2–7 - NCT05767151Recruiting
Newly diagnosed Parkinson’s study for early disease
This study looks at people newly diagnosed with Parkinson’s disease, before starting Parkinson’s medicines, to better understand early illness. It may help researchers identify patterns that could guide future treatments.
Changsha, HunanAges 30–75 - NCT05767476Recruiting
Testing cooling treatment after lack of oxygen at birth
This trial studies outcomes in newborns who had breathing problems from low oxygen before or during birth and were treated with a cooling therapy (therapeutic hypothermia). It may help doctors understand which babies benefit most and what recovery looks like over time.
RomeAges 10 minutes–6 hours - NCT05767203Recruiting
Study genetic and blood markers in people with inherited intellectual disability
This study looks at genetic-related and blood/biologic markers in people with an inherited (genetic) intellectual disability. The goal is to better understand these differences and how they might relate to the condition.
ParisAges Any age - NCT05644314Recruiting
Drug-coated stent for narrowed vertebral arteries
This trial studies whether a drug-coated stent placed in a narrowed vertebral artery can improve outcomes for people with artery narrowing from plaque. It also looks at how safe the stent is, since it requires specific blood-thinning medicines around the procedure.
Guangzhou, GuangdongAges 18 years+ - NCT05767216Recruiting
Study of genetic and epigenetic differences in twin pairs with Down syndrome
This study looks at how genetics and gene-regulation (how genes turn on and off) differ between close family members who have different Down syndrome status. Researchers hope the findings will help explain why Down syndrome outcomes can vary even in very closely related people.
ParisAges 4–11 - NCT05768490RecruitingPhase 3
Radiation plus targeted pills for EGFR lung cancer brain spots
This Phase 3 study tests whether giving brain radiation early or later, along with almonertinib (a targeted pill), works better for people with EGFR-mutated non-small cell lung cancer that has a small number of brain metastases. It aims to control brain disease while checking safety and effectiveness in a carefully selected group.
Guangdong, GuangzhouAges 18–75 - NCT05772611Recruiting
Study of immune responses in brain autoimmune and nerve syndromes
This study looks at how the immune system works in certain neurological conditions, including autoimmune encephalitis and related nerve disorders. Researchers may use blood and/or spinal fluid samples, especially when antibodies are present or can’t be found, to better understand what’s driving the illness.
LyonAges 18 years+ - NCT05773443Recruiting
Digital program plus an oral drug for Lewy body dementia
This study tests an eHealth program together with a patient-and-caregiver support program, along with a medicine called ambroxol. It aims to see whether this combined approach is safe and helpful for people with dementia with Lewy bodies (or early memory changes from it).
Haugesund, RogalandAges 50–85 - NCT03957343Recruiting
Parkwood Pacing and Planning app for concussion recovery
This study tests a smartphone or tablet app (the Parkwood Pacing and Planning app) that may help people after a mild concussion manage recovery. You may be able to join if you’re an adult, can use the app device, and have a confirmed mild concussion.
London, OntarioAges 18 years+ - NCT05527067Recruiting
Study of alpha-synuclein brain disease in patients and healthy people
This study follows people with a primary alpha-synuclein diagnosis and compares them with healthy controls. It aims to better understand this condition and may help researchers design better future tests and treatments.
Fuzhou, FujianAges 30–80 - NCT05193136Recruiting
Testing sleep and exercise effects on strength and thinking in lung disease
This trial studies whether improving sleep habits can help people with lung conditions like COPD or IPF maintain muscle strength and thinking (cognitive function). It may help by addressing sleep quality and related health factors, but eligibility depends on your current diagnoses and treatments.
Jōyō, KyotoAges 20 years+ - NCT05763706Recruiting
Laser treatment for nerve pain after chemotherapy
This trial looks at whether light (photobiomodulation) and laser-like therapy can reduce nerve pain in people who developed neuropathy after chemotherapy. If you match the chemotherapy and language requirements, you may be screened to see if this treatment is safe and helpful for your symptoms.
Hasselt, LimburgAges 18 years+ - NCT04523909Recruiting
Testing spinal fluid inflammation changes after aortic surgery
This study tracks inflammation-related lab markers in spinal fluid taken through a temporary drain during and after thoracic aortic surgery. It may help doctors understand what inflammatory changes happen around surgery and how they relate to recovery.
NijmegenAges 18 years+ - NCT05800223RecruitingPhase 3
Armatinib with or without brain radiation for EGFR lung cancer
This study tests whether armatinib alone or combined with focused brain radiation (SRT) can control brain metastases from EGFR-mutated non-small cell lung cancer. It aims to improve outcomes for people with few, mostly low-symptom brain spots.
Shanghai, Shanghai MunicipalityAges 18–75
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,934 recruiting neurology studies from the U.S. registry right now, out of 18,325 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.