Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,465 recruiting studies in this area right now.
By phase
- Not applicable9,803
- Phase 2786
- Phase 1573
- Phase 3536
- Phase 4343
- Phase 1/Phase 2304
- Phase 2/Phase 3120
Top conditions
- Stroke855
- Parkinson Disease424
- Multiple Sclerosis341
- Alzheimer Disease340
- Dementia227
- Ischemic Stroke199
- Epilepsy196
- Obstructive Sleep Apnea154
- Spinal Cord Injuries153
- Traumatic Brain Injury153
- Insomnia152
- Sarcopenia149
- Acute Ischemic Stroke141
- Cerebral Palsy130
- Mild Cognitive Impairment129
- Migraine113
- Pain Management112
- Amyotrophic Lateral Sclerosis107
Leading sponsors
- Beijing Tiantan Hospital134
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic99
- Xuanwu Hospital, Beijing95
- VA Office of Research and Development93
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- Cairo University63
Where studies are running
- California674
- Massachusetts302
- New York292
- Florida278
- Texas267
- Maryland244
- Arizona214
- Alabama211
- Illinois193
- Pennsylvania177
Recruiting studies12,463 total
- NCT06859502Recruiting
National database for cerebrovascular disease research
This study creates a national database of people with cerebrovascular diseases (conditions affecting blood flow in the brain, like stroke or aneurysm). By joining, you help researchers better understand and improve care for these conditions.
Florence, FIAges Any age - NCT06859528Recruiting
Walking program for people with Parkinson's disease
This study tests a community-based walking program designed for people with Parkinson's disease. It aims to see if regular walking can help improve movement and overall well-being.
St Louis, MissouriAges 30–85 - NCT06859996Recruiting
Cognitive rehab study for memory and focus after mild brain injury
This study tests two different types of cognitive rehabilitation (education and problem-solving strategies) delivered via video appointments. It may help people with ongoing thinking and memory problems after a mild brain injury.
Seattle, WashingtonAges 18 years+ - NCT06860035Recruiting
Support and Resources for Dementia Caregivers
This study tests a program that connects caregivers of people with dementia to helpful resources and support. If you are the main caregiver for a family member getting home health care, this study may offer you information and assistance.
New York, New YorkAges Any age - NCT06860152Recruiting
Improving speech understanding in noise with cochlear implants
This study tests how well people with cochlear implants can understand speech in noisy situations, compared to those with normal hearing. It involves a special imaging scan to see how the brain processes sound, which may help improve future implant technology.
Iowa City, IowaAges 18–99 - NCT06860932Recruiting
Palliative care program for MS and related disorders
This study tests a palliative care program designed to help people with long-term neurological conditions like MS, NMOSD, or anti-MOG disease. You will learn about managing symptoms and planning care, and the study will measure how this affects your knowledge and attitudes.
New York, New YorkAges 18–65 - NCT06861387Recruiting
Cryo nerve block for lung surgery pain
This trial tests a freezing technique to numb nerves around the lungs during minimally invasive lung surgery. It may help reduce pain after surgery, so you need less pain medication.
Nieuwegein, UtrechtAges 18 years+ - NCT06861686Recruiting
New classification for obstructive sleep apnea
This study is improving how doctors classify obstructive sleep apnea (a condition where your breathing stops and starts during sleep). It focuses on sleepiness and heart-related risks to help guide treatment. If you are 40 or older and have untreated OSA, you may be able to join.
Antwerp, AntwerpAges 40 years+ - NCT06861998Recruiting
Sleep help before heart surgery for infants and toddlers
This trial tests if helping young children with sleep problems before heart surgery can reduce confusion or agitation after surgery. It is for children ages 0 to 3 who have sleep issues and are scheduled for heart repair surgery.
BeijingAges 1 day–3 years - NCT06862297Recruiting
Comparing a new jaw tracking device to standard sleep study for sleep apnea
This study compares a new device that tracks jaw movement during sleep to the standard sleep study (polysomnography) for diagnosing sleep apnea. You may be eligible if you have symptoms like loud snoring or daytime sleepiness and have been referred for a sleep study.
TaipeiAges 20–75 - NCT06862557Recruiting
PEMF treatment for people with dementia
This study tests whether a pulsed electromagnetic field (PEMF) device can help people with mild to moderate Alzheimer's or related dementias. If you or a loved one has memory loss, this trial looks at a potential new way to support brain health without medication.
Boca Raton, FloridaAges 50–100 - NCT06862596RecruitingPhase 2/Phase 3
Mexiletine for spinal and bulbar muscular atrophy
This trial tests whether mexiletine hydrochloride can help men with spinal and bulbar muscular atrophy (SBMA) by improving muscle strength and function. It may be an option if you have mild to moderate symptoms and meet heart and medication safety checks.
Bunkyō CityAges 18–80 - NCT06863207Recruiting
Testing a new treatment for teens with stomach and nerve problems
This study tests whether a personalized nerve stimulation treatment can help teens with cyclic vomiting syndrome or functional dyspepsia who also have symptoms of autonomic dysfunction, like dizziness, fatigue, or heart palpitations when standing.
Milwaukee, WisconsinAges 11–18 - NCT06863350Recruiting
Closing a heart hole to treat drug-resistant epilepsy
This trial tests if closing a small hole in the heart (called a PFO) can reduce seizures in people whose epilepsy isn't controlled by medication. It might offer a new treatment option for those who have both drug-resistant epilepsy and this heart condition.
Chengdu, SichuanAges 18–60 - NCT06863480RecruitingPhase 1
Trial of tocilizumab for bleeding stroke to prevent later strokes
This trial tests if a drug called tocilizumab (TYENNE) can reduce the risk of delayed strokes after a bleeding stroke from a ruptured aneurysm. It is for adults who had a specific type of brain bleed and need a drain to remove fluid.
Gainesville, FloridaAges 18–89 - NCT06863571RecruitingPhase 3
Early medication combo to reduce swelling after stroke
This trial tests a combination of medicines given early after a large ischemic stroke to reduce brain swelling. It may help people who have had a stroke in the middle cerebral artery within the last 3 days and have a large area of brain damage.
Hangzhou, ZhejiangAges 18 years+ - NCT06863740Recruiting
Cannabis for Restless Legs Syndrome
This study tests whether cannabis can help people with Restless Legs Syndrome that has not improved with standard treatments. If you have RLS and other treatments haven't worked well, you may be able to join.
Toronto, OntarioAges 25 years+ - NCT06863974Recruiting
Finding markers of relapsing nerve inflammation in children
This study looks at children who have had a first attack of nerve inflammation (like ADEM, vision loss, or spinal cord issues) to find markers in the blood that might show if it will come back. It tests blood and cells to better understand the immune response.
AngersAges 18 years+ - NCT06864741Recruiting
Virtual reality rehab for stroke patients
This study tests whether virtual reality (VR) exercises can help people who have had a stroke recover arm movement. You will play specially designed VR games while in the hospital or at home to see if it improves your arm function.
Kentville, Nova ScotiaAges 18 years+ - NCT06864936Recruiting
Eye scan study for ublituximab in multiple sclerosis
This study uses a special eye scan (OCT) to see how well the MS medication ublituximab works. It compares people starting ublituximab to those on other stable MS treatments, to find better ways to measure treatment success.
Baltimore, MarylandAges 18–65 - NCT06865274Recruiting
A look at gene changes in MS, NMOSD, and MOGAD
This study looks at a specific gene change in people with MS, NMOSD, or MOGAD to see how common it is. By joining, you help researchers learn more about these conditions and possible future treatments.
Roma, RomaAges 18 years+ - NCT06865950Recruiting
Sex differences in emergency stroke care
This study looks at how men and women with suspected stroke or mini-stroke are treated by emergency services. It aims to improve care for everyone.
HomburgAges 18 years+ - NCT06866223Recruiting
Language therapy study for bilingual children ages 4–6
This study looks at how to best support bilingual children (ages 4–6) who have trouble with advanced sentences. It will test whether therapy in English, Spanish, or both helps them learn grammar more effectively.
Houston, TexasAges 4–6 - NCT06866444Recruiting
Duloxetine and Fibromyalgia: How Your Body Processes the Drug
This study looks at how well duloxetine (Cymbalta) works in people with fibromyalgia. It may help doctors understand if people respond differently based on how their body breaks down the drug.
Salt Lake City, UtahAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,465 recruiting neurology studies from the U.S. registry right now, out of 19,709 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.