Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,407 recruiting studies in this area right now.
By phase
- Not applicable9,742
- Phase 2782
- Phase 1577
- Phase 3534
- Phase 4342
- Phase 1/Phase 2307
- Phase 2/Phase 3123
Top conditions
- Stroke843
- Parkinson Disease429
- Alzheimer Disease342
- Multiple Sclerosis342
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea156
- Spinal Cord Injuries153
- Insomnia152
- Sarcopenia150
- Traumatic Brain Injury150
- Acute Ischemic Stroke138
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Migraine114
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic98
- Xuanwu Hospital, Beijing93
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California680
- Massachusetts299
- New York292
- Florida274
- Texas267
- Maryland246
- Arizona213
- Alabama209
- Illinois189
- Pennsylvania177
Recruiting studies12,405 total
- NCT04474106Recruiting
Shock wave therapy for new spinal cord injuries
This study tests whether extracorporeal shock wave therapy (non-surgical shock waves delivered from outside the body) can improve movement and sensation after a recent spinal cord injury. It may help people recover motor (movement) and sensory (feeling) function within months after injury.
Innsbruck, TyrolAges 18–99 - NCT04629469Recruiting
Two types of MRI scans in children
This study compares two MRI scan settings (a lower and higher magnetic field) in children to see how well they work for pediatric patients. It may help doctors choose the best MRI approach for kids without changing any care beyond the scan itself.
Kansas City, MissouriAges birth–22 years - NCT04115761RecruitingPhase 2
ADCv01 added to standard care for newly diagnosed glioblastoma
This Phase 2 study tests ADCV01, given “on top of” other standard treatment, for newly diagnosed glioblastoma (grade 4 brain tumor). The goal is to see whether it helps patients live longer and safely manage tumor growth.
Taichung, Non-USAges 20–75 - NCT04494295Recruiting
Minimally invasive surgery registry for bleeding in the brain
This study records and compares outcomes for people with a specific kind of sudden brain bleeding (intracerebral hemorrhage) using minimally invasive surgery. It may help doctors understand which patients benefit most and improve future care decisions.
Burbank, CaliforniaAges 18 years+ - NCT04449523Recruiting
Check for hidden heart rhythm problems after silent brain strokes
This study looks at how often “silent” atrial fibrillation—an irregular heart rhythm that can be symptom-free—happens in people who have silent brain stroke spots on MRI. If it finds a link, it may help identify which patients might benefit from closer heart monitoring or prevention steps.
GrazAges 50 years+ - NCT04276181Recruiting
Nerve and tendon transfer surgery for hand function after spinal cord injury
This trial studies a specialized surgery that reroutes nerves and tendons to help restore hand and grip function after a spinal cord injury. It may help some people regain more useful hand movement if their arm muscle strength and nerve signals are strong enough.
MölndalAges 15–55 - NCT03919305Recruiting
Study of blood clots in brain veins
This study follows people who have a blood clot in the brain’s venous drainage system. It aims to better understand this condition and may help improve how it is recognized and managed.
BeijingAges Any age - NCT04572568Recruiting
Registry to study care for brain blood vessel malformations
This study collects medical and imaging information from people with a brain arteriovenous malformation (AVM) to understand how different treatments are used in real life. It may help doctors improve future care, even if you are not receiving a new drug in this study.
Beijing, Beijing MunicipalityAges 1–80 - NCT03908502Recruiting
Study for nervous system problems after radiation therapy
This study looks at nervous system complications that can happen after receiving radiation therapy. You may be invited if you’ve had radiotherapy and can safely consent to participate.
Guangzhou, GuangdongAges birth+ - NCT04266574Recruiting
Blood pressure–guided care for older or frail surgical patients
This study tests a goal-based blood pressure treatment approach during major surgery for people at higher risk (often older or frail with high blood pressure). The goal is to see if this BRAIN-targeted strategy can improve how patients do after surgery.
Rozzano, MilanAges 18 years+ - NCT03322306Enrolling by invitation
Genetic testing study for inherited neurological conditions
This trial looks for genetic causes of inherited (in family) neurological diseases by using genetic screening. If you might have an inherited neurological condition, this study may help explain why symptoms happen and guide future care.
Hong Kong, ShatinAges 18–80 - NCT03136302Recruiting
Tracking brain signals during deep brain stimulation
This study compares two ways of measuring brain activity—MRI-based brain mapping and electrical brain testing—during deep brain stimulation. It may help doctors better target stimulation to improve symptoms like movement problems or long-lasting pain.
Halifax, Nova ScotiaAges Any age - NCT01617408Recruiting
Brain stimulation and vision testing in healthy adults
This study uses brain stimulation and brain imaging (MRI) along with vision tests to understand how the brain supports seeing. You might be eligible if you are a healthy adult and can safely complete MRI and stimulation tasks.
Bethesda, MarylandAges 18–50 - NCT05805410Recruiting
Trunk therapy in children with spastic cerebral palsy
This study looks at how special trunk (core) exercises or positioning affect movement and muscle control in children with spastic cerebral palsy (CP). It may help families understand which trunk-focused interventions improve function and comfort.
Chicago, IllinoisAges 4–12 - NCT02881970RecruitingPhase 1/Phase 2
Cord blood stem cell treatment for newborn brain injury
This early-phase study tests whether using a baby’s own cord blood stem cells is safe and feasible for newborns with brain injury from lack of oxygen around birth. It may help researchers find new ways to treat hypoxic-ischemic encephalopathy (brain injury due to oxygen deprivation) in addition to standard care like cooling.
MarseilleAges 1 day–3 days - NCT03758521Recruiting
Natural history study of SSADH deficiency in children and adults
This study tracks how SSADH deficiency (a genetic condition) affects health over time. There is no new drug being tested; instead, researchers collect medical history and perform certain optional scans/tests that can help describe disease patterns and future treatment needs.
Boston, MassachusettsAges Any age - NCT03299179Recruiting
Female hormones and brain blood flow during MRI
This study checks how female hormones may change blood flow in the brain. You may be asked to undergo an MRI scan while hormone levels are assessed.
GhentAges 18–25 - NCT05124951RecruitingPhase 2
Tested a treatment for specific brain germ cell tumors
This Phase 2 trial studies WVI for children and young adults with a newly diagnosed germ cell tumor in one side of the basal ganglia/thalamus. It aims to see how well the treatment works for tumors without spread within the brain.
BeijingAges 3–30 - NCT06933537Recruiting
Personalized brain stimulation for emotional disorders in MS and NMOSD
This trial tests if a gentle brain stimulation technique can help with anxiety in people with multiple sclerosis (MS) or neuromyelitis optica spectrum disorder (NMOSD). It uses a mild electrical current through the scalp to regulate mood, and the treatment is customized to each person.
Beijing, Beijing MunicipalityAges 18–65 - NCT05294068Recruiting
Study barriers to physical activity in aging with disabilities
This study looks at what makes it hard or easier for people with cognitive, physical movement, or sensory (hearing/vision) impairments to be active as they age. It may help improve support and services for physical activity at a rehabilitation/parasport clinic.
GarchesAges 6 years+ - NCT02804438Recruiting
Pupil measurement checks in neurocritical care patients
This study collects normal (baseline) results from a handheld eye pupil camera (a pupillometer) used during routine neuro–intensive care checks. It may help clinicians better interpret these eye measurements in future patients.
Dallas, TexasAges Any age - NCT02550522Recruiting
Using brain signals to control a powered exoskeleton
This trial tests whether a brain-computer interface can help you control a powered leg exoskeleton. If you have stable long-term nerve/movement problems and need better mobility, the device may help you move with more independence.
GrenobleAges 18–55 - NCT05303363Recruiting
Checking brain blood flow during a breathing heart-lung machine
This study monitors how much blood is reaching the brain in adults who need a specific type of life-support called VV-ECMO. The goal is to better understand brain blood flow and how monitoring may help manage care during ECMO.
Amsterdam-ZuidoostAges 18–100 - NCT05525325Recruiting
Sedation method during clot removal for posterior stroke
This study compares different ways of giving sedation during a procedure to remove blood clots in strokes caused by blocked vertebral or basilar arteries. The goal is to see which sedation approach is safest and works best for patients undergoing endovascular treatment.
Heidelberg, Baden-WurttembergAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,407 recruiting neurology studies from the U.S. registry right now, out of 19,276 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.