Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 11,939 recruiting studies in this area right now.
By phase
- Not applicable9,342
- Phase 2765
- Phase 1556
- Phase 3513
- Phase 4339
- Phase 1/Phase 2299
- Phase 2/Phase 3125
Top conditions
- Stroke796
- Parkinson Disease394
- Alzheimer Disease338
- Multiple Sclerosis330
- Dementia225
- Epilepsy192
- Ischemic Stroke190
- Insomnia159
- Traumatic Brain Injury151
- Obstructive Sleep Apnea142
- Spinal Cord Injuries142
- Acute Ischemic Stroke139
- Sarcopenia135
- Mild Cognitive Impairment126
- Cerebral Palsy119
- Pain Management113
- Migraine107
- Fibromyalgia105
Leading sponsors
- Beijing Tiantan Hospital124
- Assistance Publique - Hôpitaux de Paris109
- Riphah International University105
- Mayo Clinic98
- VA Office of Research and Development92
- Xuanwu Hospital, Beijing89
- Hospices Civils de Lyon77
- Johns Hopkins University69
- University of Minnesota63
- Washington University School of Medicine63
Where studies are running
- California658
- Massachusetts304
- New York295
- Florida267
- Texas266
- Maryland248
- Arizona208
- Alabama207
- Illinois183
- Pennsylvania176
Recruiting studies11,939 total
- NCT07777861RecruitingPhase 2
Testing an eye drop for worsening glaucoma
This study tests an eye drop (G01) for people with primary open-angle glaucoma that is getting worse despite current treatments. It aims to see if G01 can safely slow down or stop the progression of glaucoma.
Beijing, Beijing MunicipalityAges 18–80 - NCT07777484RecruitingPhase 1
Study of TRB-001 vaccine for Parkinson's disease after prior immunotherapy
This study tests an experimental vaccine called TRB-001 in people with Parkinson's disease who have already received a previous immunotherapy targeting alpha-synuclein. The goal is to see if the vaccine is safe and how it affects the immune system and the disease.
ViennaAges 18 years+ - NCT07778836RecruitingPhase 3
Study of daily injections for Friedreich's ataxia
This study tests an investigational drug given as a daily injection to see if it can improve walking and balance in people with Friedreich's ataxia.
Tampa, FloridaAges 12–40 - NCT05509387Recruiting
Stronger brain stimulation to improve naming in Alzheimer’s
This trial tests whether a stronger form of gentle brain stimulation (tDCS) can help people with mild to moderate Alzheimer’s improve word-finding (naming). If you qualify, you’ll be assessed before and during the study to see whether the stimulation improves naming ability.
Toronto, OntarioAges 50–90 - NCT06050603Recruiting
MRI guided brain stimulation study for memory
This study tests a new way to use brain stimulation guided by MRI to understand memory. It may help people with mild memory problems or healthy volunteers.
Toronto, OntarioAges 18–80 - NCT06551402RecruitingPhase 3
Dabigatran vs rivaroxaban for cerebral venous thrombosis
This study compares two blood thinners (dabigatran and rivaroxaban) to see which works better for treating a blood clot in the brain's veins. You may be eligible if you have a new diagnosis of this type of stroke and can start treatment within 14 days.
Kafr ash ShaykhAges 18–75 - NCT05449119Recruiting
Study links gut health, diet, and thinking and movement in seniors
This study looks at how differences in gut bacteria and nutrition may relate to changes in thinking and movement in people over 75 who have a reduced appetite (“small eaters”). It may help doctors better understand what could be contributing to these problems and how nutrition might play a role.
DijonAges 75 years+ - NCT07777978Recruiting
Home exercise and education for chronic venous insufficiency
This study tests a structured home-based exercise and education program for people with chronic venous insufficiency – a condition where veins in the legs have trouble sending blood back to the heart. If you qualify, you would do the program for 12 weeks to see if it helps improve your symptoms.
Bolu, BoluAges 18 years+ - NCT07781670Recruiting
Brain and body responses to physical and emotional stress
This study looks at how your brain and body (heart rate, etc.) respond to sudden physical and emotional stress. You will do tasks like placing your hand in cold water or viewing emotional images while we record your brain activity with EEG. The results may help understand how stress affects health.
Pavia, LombardyAges 18 years+ - NCT07781566Recruiting
Speech therapy intensity for cleft palate speech errors in children
This study looks at how well two different intensities of speech therapy work for children with a cleft palate who have speech sound errors. It aims to find the best way to help your child speak more clearly.
Ghent, East-FlandersAges 4 years+ - NCT07775833Recruiting
Mushroom supplement to slow memory decline in at-risk adults
This trial tests whether eating mushrooms regularly can help prevent memory loss in people who are at higher risk for Alzheimer's disease but do not have dementia. If you are between 45 and 80, have some memory concerns, and currently eat mushrooms rarely, this study may be a good fit.
SingaporeAges 45–80 - NCT07777081Recruiting
How your brain and body recover after a wrist fracture
This study looks at how your brain and body heal after a wrist fracture. By joining, you'll help doctors understand recovery better, which could improve care for future patients.
Cambridge, CambridgeshireAges 18 years+ - NCT07776444Recruiting
Measuring brain blood flow with light and MRI
This study uses a special light-based device and MRI to measure how blood vessels in the brain respond to changes. It may help researchers better understand blood flow in people with and without sickle cell disease.
St Louis, MissouriAges 6–70 - NCT07779486Recruiting
Intravenous magnesium for acute headache pain relief
This study compares two doses of intravenous (IV) magnesium to see which is more effective at relieving acute headache pain in the emergency department. It aims to provide a fast and effective treatment option for migraine, tension-type, or cluster headaches.
MonastirAges 18 years+ - NCT07776873RecruitingPhase 3
Clot-busting medicine for stroke symptoms 4.5 to 24 hours
This study tests a clot-busting medicine given through an IV to people who had a stroke caused by a blocked medium-sized blood vessel in the brain, and who can be treated 4.5 to 24 hours after symptoms start. The goal is to see if it improves recovery and reduces disability compared to standard care.
Hefei, AnhuiAges 18 years+ - NCT07776379Recruiting
Predicting recovery with BDNF blood levels in chronic low back pain
This study looks at whether a protein in your blood, called BDNF, can help predict how well you might do with chronic low back pain. By participating, you may help doctors better understand and treat this condition.
Daegu, DaeguAges 20–80 - NCT07783074Recruiting
Fatigue study using digital outcomes in multiple sclerosis and long COVID
This study is investigating fatigue using digital outcomes in people with multiple sclerosis, long COVID, and healthy volunteers. Participants must own a smartphone, be fluent in German or English, and be willing to provide informed consent. Exclusion criteria include having taken certain medications recently, being pregnant or lactating, or having additional health conditions that could affect fatigue or the autonomic nervous system.
Basel, BaselAges 18–65 - NCT07778810RecruitingPhase 2
Cannabidiol before seizures in infants with Sturge-Weber syndrome
This study tests whether starting the medication Epidiolex (a purified form of cannabidiol) before any seizures occur can help prevent or delay seizures in infants with Sturge-Weber syndrome.
Baltimore, MarylandAges 1 month–1.5 years - NCT07775872Recruiting
Study of polg-related disease over time
This study follows people of all ages with a confirmed POLG-related disease to learn how the condition changes over time. The information collected may help design better care and future treatments.
San Diego, CaliforniaAges Any age - NCT07779759Recruiting
Speech therapy intensity for children with speech sound disorders
This study compares two different levels of speech therapy (high-intensity versus low-intensity) to see which is more effective for children aged 4 to 12 who have difficulty making certain speech sounds correctly.
GhentAges 4–12 - NCT07782216Recruiting
Studying brain proteins after acute brain injury
This study looks at how certain brain proteins (called biomarkers) behave in the blood after an acute brain injury. The goal is to see if these proteins can help doctors quickly assess the severity of the injury. Participation involves giving blood samples at specific times after your injury.
Pécs, BranyaAges 18 years+ - NCT07776275Recruiting
Headache study comparing neck pain patients with healthy people
This study looks at physical differences between people with cervicogenic headache (a headache that starts in the neck), people with chronic neck pain without headache, and healthy controls. By comparing these groups, researchers hope to better understand what causes the headache and which physical features are specific to it.
Istanbul, SefaköyAges 25–60 - NCT07777419Recruiting
Thinking and mood after brain stimulation for Parkinson's
This study looks at how deep brain stimulation (a treatment that uses mild electrical pulses to help control movement) affects thinking and mood in people with Parkinson's disease. It is a joint study by a Swiss university hospital that uses records from usual care and tests over time.
BernAges 18–75 - NCT07783828Recruiting
Chatbot-guided exercise for brain injury recovery
This trial tests whether a smartphone chatbot can help people recovering from a mild brain injury stick to a personalized, guided exercise program. It aims to improve their physical and mental well-being during recovery.
TaipeiAges 18 years+
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 11,939 recruiting neurology studies from the U.S. registry right now, out of 18,371 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.