Neurology
Brain & nervous system clinical trials
Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We’re tracking 12,407 recruiting studies in this area right now.
By phase
- Not applicable9,742
- Phase 2782
- Phase 1577
- Phase 3534
- Phase 4342
- Phase 1/Phase 2307
- Phase 2/Phase 3123
Top conditions
- Stroke843
- Parkinson Disease429
- Alzheimer Disease342
- Multiple Sclerosis342
- Dementia226
- Ischemic Stroke200
- Epilepsy197
- Obstructive Sleep Apnea156
- Spinal Cord Injuries153
- Insomnia152
- Sarcopenia150
- Traumatic Brain Injury150
- Acute Ischemic Stroke138
- Cerebral Palsy131
- Mild Cognitive Impairment129
- Migraine114
- Pain Management113
- Amyotrophic Lateral Sclerosis108
Leading sponsors
- Beijing Tiantan Hospital133
- Riphah International University125
- Assistance Publique - Hôpitaux de Paris112
- Mayo Clinic98
- Xuanwu Hospital, Beijing93
- VA Office of Research and Development92
- Hospices Civils de Lyon79
- Johns Hopkins University70
- National Taiwan University Hospital70
- University of Minnesota64
Where studies are running
- California680
- Massachusetts299
- New York292
- Florida274
- Texas267
- Maryland246
- Arizona213
- Alabama209
- Illinois189
- Pennsylvania177
Recruiting studies12,405 total
- NCT04391465Recruiting
Blood flow and heart rate during a heart procedure study
This study looks at how changes in blood flow in the brain relate to heart rate during a specific heart rhythm procedure. It may help doctors better understand how the body’s brain and heart responses connect during temporary pacing.
Calgary, AlbertaAges 18–70 - NCT06517043Recruiting
Balance training for older adults with slow walking
This study looks at how older adults learn and keep balance skills. It tests a training program to help people who walk slowly and have balance problems. The goal is to improve walking and reduce fall risk.
Gainesville, FloridaAges 65–95 - NCT06534645Recruiting
STOP-stroke: Predicting recovery after a stroke
This study collects health data from people with a suspected stroke to improve predictions of recovery. Your participation helps researchers better understand how to treat strokes in the future.
ZurichAges Any age - NCT06473298Recruiting
Light tracking therapy for kids with one-sided muscle tightness
This study tests a special light-tracking activity to help children with spastic hemiplegia (tightness on one side) improve their movement. It's for kids ages 4–7 who can walk and have mild muscle tightness.
CairoAges 4–7 - NCT06201611RecruitingPhase 2/Phase 3
Nebivolol for diabetic nerve damage study
This study tests whether the drug nebivolol (a type of beta-blocker) can help slow or reverse nerve damage caused by diabetes. It is for people with recent diabetes and confirmed neuropathy.
Bangalore, KarnatakaAges Up to 18 years - NCT06204315RecruitingPhase 2
Spine radiosurgery for spinal cord compression
This trial tests a precise radiation technique for people whose spinal tumors are very close to the spinal cord or nerves. It aims to safely give higher radiation doses while limiting damage to the cord.
Houston, TexasAges 18 years+ - NCT06179719Recruiting
Brain activity during propofol anesthesia
This study looks at how the anesthetic propofol affects the brain. It uses MRI and EEG to monitor brain activity during anesthesia, helping researchers understand how consciousness is lost.
Munich, BavariaAges 18–35 - NCT06175000RecruitingPhase 2
Maintenance obinutuzumab for central nervous system lymphoma
This trial tests whether a maintenance drug called obinutuzumab can help prevent relapse in people with primary central nervous system lymphoma (a rare lymphoma in the brain or spine) who have already responded to initial chemotherapy. It is for those who have achieved at least a partial or complete response to their first treatment.
New York, New YorkAges 18 years+ - NCT06490484RecruitingPhase 2
A new capsule for diabetic nerve pain when pregabalin doesn't work
This trial tests an experimental drug (HSK16149) for people with long-term diabetic nerve pain that hasn't been helped enough by pregabalin. It aims to see if the new capsule can reduce pain more effectively.
Hangzhou, ZhejiangAges 18–75 - NCT06489106Enrolling by invitation
Spinal stimulation to improve hand function in kids with spinal cord injury
This study tests a noninvasive spinal stimulation device to help children with spinal cord injury regain hand strength and control. It may improve grip and daily activities.
Louisville, KentuckyAges 7–12 - NCT05843396Recruiting
Study of newborn brain development and response to care
This study looks at how newborns’ brains develop and how they respond to an intervention. It helps researchers understand brain organization in individual babies so care can improve in the future.
Minneapolis, MinnesotaAges Any age - NCT06464536Recruiting
Tight gloves for nerve protection during taxane chemo
This study tests whether wearing tight surgical gloves during taxane chemotherapy can help reduce nerve damage in the hands and feet. It may be a good fit if you have breast or urogenital cancer and are starting taxane treatment for the first time.
ZurichAges 18 years+ - NCT06486779Recruiting
Study of Kesimpta in Greek MS Patients
This study watches how well Kesimpta (ofatumumab) works for people with relapsing multiple sclerosis over time. It collects information from routine doctor visits and scans to see if the treatment is controlling the disease.
Athens, AtticaAges 18–55 - NCT06430164Recruiting
Brain and walking study for healthy adults
This study looks at how the brain controls walking in healthy people. You will walk on a treadmill while we measure your brain activity and leg muscles. It helps us understand normal walking so we can better help people with walking problems.
Atlanta, GeorgiaAges 18–65 - NCT06444568Recruiting
Ketogenic diet for memory loss in older adults
This trial tests whether a modified ketogenic diet (high in healthy fats, low in carbs) can help people with mild memory problems. It is for older adults who have been diagnosed with a certain type of memory impairment and want to see if diet changes can support brain health.
AnkaraAges 65–80 - NCT06418594RecruitingPhase 2
Drug combo for HER2-negative breast cancer brain metastasis
This trial tests a combination of two drugs (adebrelimab and apatinib) plus chemotherapy for women with HER2-negative breast cancer that has spread to the brain. It aims to see if this treatment can help shrink or control brain tumors.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07654504Recruiting
Turkish questionnaire study for brachial plexus birth palsy
This study tests a Turkish version of a questionnaire about how brachial plexus birth palsy (a nerve injury at birth affecting arm movement) impacts daily life. It may help people understand and communicate their symptoms better.
Istanbul, IstanbulAges 18 years+ - NCT07426965Recruiting
Ultrasound findings and pain in stroke patients with shoulder pain
This study uses ultrasound to look at the shoulder on the side affected by stroke and see how it relates to pain. It may help understand why shoulder pain happens after a stroke.
AnkaraAges 18–75 - NCT06370182Recruiting
New catheter for clot removal in disabling stroke
This trial tests a new catheter device (ANA Funnel) for removing large blood clots from the brain in people having a disabling stroke. The goal is to see if it safely removes clots better than standard treatment.
Jacksonville, FloridaAges 22–85 - NCT06423118Recruiting
Sleep apnea and thinking skills in older adults
This study looks at how sleep apnea affects thinking and memory in older adults. If you join, you'll wear comfortable, non-invasive sensors overnight to monitor your sleep and breathing patterns.
Toronto, OntarioAges 55–85 - NCT06421051Recruiting
Ear nerve stimulation for better sleep after surgery in older adults
This study tests whether gentle electrical stimulation of a nerve in the ear can help older adults sleep better after surgery. It's for people 65 and older having planned surgeries that don't involve the brain.
Beijing, Beijing MunicipalityAges 65 years+ - NCT04793685RecruitingPhase 2
Prazosin for alcohol withdrawal symptoms in alcohol use disorder
This study tests whether prazosin can reduce symptoms that happen when someone stops or cuts back on heavy drinking. It may help people with moderate-to-severe alcohol use disorder who also have alcohol withdrawal symptoms.
New Haven, ConnecticutAges 18–70 - NCT05417542Recruiting
Study how young brains hear rhythms
This study looks at how babies’ brains process rhythm and sound. It may help researchers understand early brain development, especially from premature birth through infancy.
AmiensAges birth–18 years - NCT06375681Recruiting
Brain training study for younger and older adults
This study compares different types of memory and thinking exercises in younger and older healthy adults. It tests whether a specific computer-based training program can improve mental abilities like attention and problem-solving.
Riverside, CaliforniaAges 18–85
Common questions
- How many brain & nervous system clinical trials are recruiting?
- Clin2 is tracking 12,407 recruiting neurology studies from the U.S. registry right now, out of 19,276 we cover in this area in total.
- What does “Brain & nervous system” cover here?
- Conditions of the brain, spinal cord, and nerves — including stroke, dementia, and movement disorders. We group each study into brain & nervous system based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a brain & nervous system trial near me?
- Use the search to filter brain & nervous system studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.