Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,816 recruiting studies in this area right now.
By phase
- Not applicable1,252
- Phase 3131
- Phase 2121
- Phase 1120
- Phase 491
- Phase 1/Phase 285
- Phase 2/Phase 316
Top conditions
- Glaucoma108
- Cataract90
- Myopia89
- Diabetic Retinopathy53
- Dry Eye42
- Keratoconus34
- Age-Related Macular Degeneration33
- Retinitis Pigmentosa31
- Sjogren's Syndrome29
- Diabetic Macular Edema26
- Eye Diseases26
- Graves Disease26
- Amblyopia24
- Astigmatism23
- Dry Eye Disease (DED)23
- Multiple Sclerosis23
- Retinal Disease23
- Macular Degeneration22
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University28
- Second Affiliated Hospital, School of Medicine, Zhejiang University23
- Medical University of Vienna19
- Fondation Ophtalmologique Adolphe de Rothschild18
- National Taiwan University Hospital17
- Assistance Publique - Hôpitaux de Paris16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- Shanghai Eye Disease Prevention and Treatment Center15
- Duke University13
Where studies are running
- California143
- Arizona66
- Texas41
- Maryland39
- New York34
- Massachusetts33
- Florida32
- Alabama27
- North Carolina21
- Pennsylvania21
Recruiting studies1,816 total
- NCT02014389Recruiting
Testing pupil measurements with colored light in eye exams
This study checks how well a device can measure how your pupils respond to colored light. It may help improve eye testing, especially when monitoring certain vision and nerve conditions.
Tel LitwinskyAges 18–80 - NCT01401998Recruiting
Study collecting information from people with ARPKD
This study looks at medical records, imaging, and genetic testing for people with autosomal recessive polycystic kidney disease (ARPKD). It may help researchers better understand the condition and how it affects the liver and kidneys.
Washington D.C., District of ColumbiaAges Up to 18 years - NCT02026843Recruiting
Testing eye fluid markers in chorioretinal eye diseases
This study looks at substances (“biomarkers”) in the clear fluid inside the eye to better understand several eye conditions that affect vision. Your results may help doctors learn how these diseases work and how treatments might be chosen.
Daegu, KyungsangpookdoAges 20–80 - NCT01962415RecruitingPhase 2
Reduced-intensity stem cell transplant for non-cancer disorders
This trial tests whether a gentler (reduced-intensity) conditioning treatment before a stem cell transplant works for non-cancer diseases. It uses specific donor stem cell matches and checks heart, lung, liver, and kidney function to help lower transplant stress while still aiming for benefit.
Pittsburgh, PennsylvaniaAges 2 months–55 years - NCT01485575Recruiting
Blue or green dye eye surgery to help remove retinal tissue
This trial studies an eye surgery technique that uses a colored dye (blue or green) to help the surgeon carefully remove a thin inner retinal layer. It may help make the procedure more precise and safer, and the study compares how the dye-assisted method works.
LinzAges 18 years+ - NCT01496625Recruiting
Biobank study for retinal diseases and comparison samples
This study collects and stores blood and eye-related medical information to help researchers better understand retinal diseases, including age-related macular degeneration and diabetic retinopathy. Your samples may also be used to compare people with retinal disease to people without it.
Bethesda, MarylandAges 2–120 - NCT01793168Recruiting
Rare disease registry and history study
This study keeps a registry (a structured list) of people with rare diseases and may also track how the condition changes over time. It can help researchers better understand rare illnesses and find gaps in care, which may improve future treatments.
Sioux Falls, South DakotaAges Any age - NCT00341744Recruiting
Access to learning for children with low vision
This trial aims to help children with low vision access the visual environment needed for school, especially for learning to read. It may help by supporting how vision is used for reading in everyday school activities.
Nashville, TennesseeAges 3–21 - NCT01243931Recruiting
Eye scan guided laser surgery for surface cornea scars
This study tests a laser procedure guided by an eye scan to improve vision caused by surface (front) cornea cloudiness or irregularities. It may help some people whose vision problem is mainly in the outer cornea and can be safely treated without reaching deep tissue.
Portland, OregonAges 18 years+ - NCT01438658Recruiting
Test blood markers to help diagnose metastatic uveal melanoma
This study checks whether blood “biomarkers” (measurable signs in serum) can help diagnose metastatic uveal melanoma. If you have uveal melanoma, the study may look at how useful these blood tests are for spotting spread to other parts of the body.
JerusalemAges Any age - NCT00532051Recruiting
Test eye scans to choose the right cataract lens power
This study is looking at how special eye scans (optical coherence tomography, or OCT) can help doctors calculate the correct power of a cataract lens after you’ve had laser vision correction before. It may help improve how well your new lens matches your eye after prior laser treatment.
Portland, OregonAges 18 years+ - NCT00874783Recruiting
Testing nerve-cell growth from donated body cells
This trial uses donated body cells or small hair samples from people with neurological diseases (and healthy donors) to try to grow “nerve-like” cells for research. It may help scientists learn how to better study and treat different neurological conditions.
Jerusalem, IsraelAges 18 years+ - NCT02025023RecruitingPhase 3
5-FU injection for eyelid bumps called chalazia
This trial compares a specific medicine injection (5-fluorouracil) to treat chalazia, which are non-cancerous eyelid bumps. It may help reduce the bump when other approaches haven’t worked yet.
Seattle, WashingtonAges 18 years+ - NCT00981396RecruitingEarly Phase 1
EFT therapy to help smokers who struggle to quit
This early-stage study tests Emotional Freedom Techniques (EFT), a gentle talking-and-tapping method, for people who feel very anxious about quitting and still have strong cravings. It may help improve confidence and reduce the emotional triggers that make quitting harder.
Ormskirk, LancashireAges 12–99 - NCT01109394Recruiting
Help study tumors with sample testing and a research biology library
This study collects tumor (or related) samples to analyze their genes and build a shared research “biobank.” It may help researchers understand cancers better for future diagnosis and treatments.
Washington D.C., District of ColumbiaAges 4 weeks+ - NCT01145196Recruiting
Study drug eye damage and genes in Plaquenil users
This study looks at how Plaquenil (hydroxychloroquine) can harm the retina (the eye’s light-sensing layer) and whether genetics affect who gets affected. You may help by sharing medical details and providing an eye-related blood sample so researchers can compare gene patterns to eye findings.
Bethesda, MarylandAges 18–120 - NCT01756365Recruiting
Stem cell eye treatment from your own cornea cells
This trial tests an eye treatment made from your own cornea surface cells, grown in a lab and put back into the eye. It may help people with limbal stem cell deficiency by improving the health of the eye surface after a cell biopsy.
Toronto, OntarioAges 1 year+ - NCT02317328Recruiting
Adaptive eye imaging to take very detailed retinal pictures
This study uses special “adaptive optics” equipment to capture very detailed images of the retina (the nerve layer at the back of the eye). It may help improve eye tests for people with eye disease and also includes some healthy volunteers.
Bethesda, MarylandAges 12–120 - NCT02329210Recruiting
Registry study for people with Bardet-Biedl syndrome
This study is a registry that collects health and genetic information from people with Bardet-Biedl syndrome. It may help researchers better understand the condition and improve future care by building a clear group of eligible patients.
Marshfield, WisconsinAges Any age - NCT02576483Recruiting
Compare LASIK, SMILE, and PRK for eye prescription correction
This study compares three laser eye surgeries—LASIK, SMILE, and PRK—to see which works best for people who have similar eye prescription needs. You may be a good fit if you’ve never had vision-correcting surgery before and you meet the eye-health safety checks.
Palo Alto, CaliforniaAges 21–62 - NCT02118922Recruiting
Testing a light-scanning eye exam to diagnose corneal thinning
This study tests whether a special “Brillouin” microscope scan can spot corneal ectasia and related cornea conditions. It may help doctors diagnose problems earlier and better sort out who needs closer eye care.
Boston, MassachusettsAges 20–75 - NCT02182921Recruiting
Cataract surgery outcomes study
This study looks at how cataract surgery affects patients’ vision and recovery. You may be invited if you have cataracts and can participate in eye exams, and if mental health or thinking issues won’t interfere with the study.
Shanghai, Shanghai MunicipalityAges Up to 90 years - NCT02435940Recruiting
Registry for inherited eye vision conditions
This study is a registry, meaning it collects information about people with inherited retinal (retina) diseases. It may help researchers learn how these conditions progress and connect you with future studies or treatments.
Columbia, MarylandAges Any age - NCT02141308Recruiting
OCT eye imaging for rare retinal and choroid diseases
This trial studies rare diseases affecting the retina or choroid using detailed eye scans (OCT). It may help doctors better understand how these conditions look in the eye and how imaging findings relate to vision.
Portland, OregonAges 7–100
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,816 recruiting ophthalmology studies from the U.S. registry right now, out of 2,924 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.