Ophthalmology
Eyes & vision clinical trials
Eye disease and conditions that affect sight. We’re tracking 1,760 recruiting studies in this area right now.
By phase
- Not applicable1,199
- Phase 3133
- Phase 2119
- Phase 1117
- Phase 492
- Phase 1/Phase 286
- Phase 2/Phase 314
Top conditions
- Glaucoma107
- Myopia88
- Cataract76
- Diabetic Retinopathy51
- Dry Eye38
- Keratoconus34
- Retinitis Pigmentosa33
- Age-Related Macular Degeneration31
- Amblyopia26
- Eye Diseases24
- Graves Disease24
- Sjogren's Syndrome24
- Dry Eye Disease (DED)23
- Multiple Sclerosis22
- Astigmatism21
- Ocular Hypertension21
- Diabetic Macular Edema20
- Macular Degeneration20
Leading sponsors
- Zhongshan Ophthalmic Center, Sun Yat-sen University25
- Medical University of Vienna20
- Second Affiliated Hospital, Zhejiang University, School of Medicine19
- Fondation Ophtalmologique Adolphe de Rothschild18
- Assistance Publique - Hôpitaux de Paris16
- The Hong Kong Polytechnic University16
- Eye & ENT Hospital of Fudan University15
- National Eye Institute (NEI)15
- National Taiwan University Hospital15
- Shanghai Eye Disease Prevention and Treatment Center15
Where studies are running
- California133
- Arizona69
- Florida43
- Maryland39
- Texas37
- Massachusetts35
- New York35
- Alabama26
- North Carolina20
- Pennsylvania20
Recruiting studies1,760 total
- NCT05909761Recruiting
Pregnancy Uplizna safety study in women with NMOSD
This is an observational study that looks at the safety of Uplizna (satralizumab) during pregnancy for women who have neuromyelitis optica spectrum disorder (NMOSD). You may be asked to share information because your exposure to Uplizna happened during pregnancy or just before conception.
Aurora, ColoradoAges 15 years+ - NCT05206877RecruitingPhase 1
Topical insulin eyedrops for glaucoma-related eye nerve damage
This Phase 1 study tests an insulin-based eye treatment to see if it’s safe and potentially helpful for people with glaucoma-related optic nerve damage. If you may be eligible, you’ll have a close eye exam and repeated vision testing, mainly focused on one study eye.
Palo Alto, CaliforniaAges 18 years+ - NCT05859997Enrolling by invitation
CAR-T cell therapy for active autoimmune disease flare-ups
This study tests an immune-cell treatment (CAR-T, called BRL-301) in people with certain autoimmune diseases that are active and hard to control. It may help your immune system calm down if standard treatments have not worked or your disease has returned.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT05865457Recruiting
Testing two eye treatments for dry eye symptoms
This trial compares two different dry-eye eye drops to see which works better and is safe. You may be able to join if you’ve had dry eye for at least 3 months and meet specific eye-test results.
GrazAges 18 years+ - NCT05865379Recruiting
Tested eye drops for dry eye relief and safety
This trial studies whether BUFY01 eye drops work better than SVS20 for treating dry eye disease. You may be able to join if you have dry eye symptoms for at least 3 months and meet eye exam score and tear-test requirements.
LeuvenAges 18 years+ - NCT05851287Recruiting
Eye and health check study for adults 65 and older
This study enrolls people age 65+ to get regular eye and general health checkups. It may help doctors understand what eye problems are developing and how to catch them earlier.
Guangzhou, GuangdongAges 65 years+ - NCT05856786Recruiting
Study how eye focusing surgery changes OCT measurements
This study looks at how refractive (vision-focusing) surgery affects OCT test images inside the eye. It may help doctors measure and track eye changes more accurately after surgery.
Omaha, NebraskaAges 19 years+ - NCT04225611RecruitingPhase 1/Phase 2
Drug-delivering contact lens for recurrent macular swelling
This study tests a special contact lens that slowly delivers anti-inflammatory/steroid medicine to the back of the eye. It aims to treat cystoid macular edema that keeps coming back and may improve vision for people who respond to steroid treatment.
Boston, MassachusettsAges 18–85 - NCT04681417RecruitingPhase 2/Phase 3
Eye-sparing treatment options for children with retinoblastoma
This trial studies whether newer “save-the-eye” treatment plans can control retinoblastoma (eye cancer) while keeping vision as good as possible. It compares different conservative treatment strategies depending on how the tumor looks and where it is.
Saint-Denis, La RéunionAges 6 months–6 years - NCT05844982RecruitingPhase 3
Eye injections or steroid implant to prevent vision loss
This trial studies ways to prevent worsening vision caused by radiation damage to the retina after plaque brachytherapy for uveal melanoma. You may be randomly assigned to a medication injection, a steroid implant, or observation to see which approach best protects vision.
Palo Alto, CaliforniaAges 18 years+ - NCT05822089Recruiting
Comparing two cataract lens types in the same person
This study compares two different cataract (intraocular) lens options in each eye of the same person. It aims to see which lens gives better distance vision after standard cataract surgery.
ViennaAges 50–100 - NCT05767047RecruitingPhase 3
Apremilast study for children with mouth ulcers from Behçet’s
This trial studies whether apremilast can help reduce mouth ulcers in children who have Behçet’s disease or juvenile psoriatic arthritis. You may be considered if your child finished a main study and is under 18, and can safely continue treatment.
ThessalonikiAges 5–18 - NCT05344274RecruitingPhase 4
Eye blood flow study in people with glaucoma
This study measures how blood flows in the retina and how well the eye regulates that flow. It compares people with early or very early glaucoma to people without glaucoma to see what differences may predict progression.
Baltimore, MarylandAges 18–88 - NCT05803785RecruitingPhase 1
Safety study of an injection for wet macular degeneration
This Phase 1 trial tests whether BBC1501, an injection given into the eye, is safe for people with wet age-related macular degeneration (nAMD). It mainly looks at side effects and whether the study injections can be given safely in patients who still have active disease despite prior anti-VEGF treatments.
Sydney, New South WalesAges 50 years+ - NCT05801471Recruiting
Tracking vision field changes in glaucoma patients
This study looks at different ways to measure how glaucoma affects your vision over time by comparing visual field results. It may help researchers find better models to track progression so treatment decisions can be made more accurately.
Milan, MilanoAges 40–90 - NCT05802329RecruitingPhase 1
Testing eye injections for diabetic macular swelling
This Phase 1 study tests the safety and early effectiveness of OCU200 eye injections in people with diabetic macular edema (DME) that affects the center of vision. It may help by reducing the eye swelling that blurs vision from diabetes.
Deerfield Beach, FloridaAges 18 years+ - NCT05759780Recruiting
Check how an eye probe measures tissue softness
This study uses a special eye/skin/gum imaging test to measure how tissues behave. It may help researchers improve noninvasive ways to understand eye and tissue health, and in some parts of the study, mild keratoconus.
Boston, MassachusettsAges 18–75 - NCT05770661Recruiting
Study of eye growth length in children in China
This study looks at how a child’s eye “length” changes as they grow. It may help researchers understand patterns in eye development and who may be at higher risk for future vision problems.
Shanghai, Shanghai MunicipalityAges 3–18 - NCT02886611Recruiting
Study for genetic eye surface stem cell problems
This trial studies people whose eye surface problems are caused by an inherited (genetic) condition. It aims to better understand how specific genetic changes relate to symptoms, which may guide more personalized care.
ParisAges Any age - NCT05726058Recruiting
Imaging eye blood flow to assess glaucoma
This study uses special imaging to look at blood flow in the eye to help assess or better understand glaucoma. You may be eligible if you’re an adult with eye exams that fit the study’s specific eye-health and imaging requirements.
Baltimore, MarylandAges 18–88 - NCT05742321Recruiting
Study how corneal cell genetics relate to Fuchs’ disease
This study looks at how a person’s corneal cell genetic makeup relates to what happens in Fuchs’ corneal endothelial dystrophy. It may help doctors understand the disease better and guide future care, especially if you need a corneal transplant.
Saint-EtienneAges 18 years+ - NCT05549258RecruitingPhase 2
Inebilizumab for children with NMOSD who had recent relapses
This trial studies whether inebilizumab can reduce illness activity in children with neuromyelitis optica spectrum disorder (NMOSD), a condition that can cause attacks affecting the eyes and spinal cord. It focuses on kids who have had recent relapses, meaning symptoms came back or worsened.
La Jolla, CaliforniaAges 2–17 - NCT05696561Recruiting
Testing a glaucoma procedure called canaloplasty device
This trial studies whether a canaloplasty device is safe and effective for people with open-angle glaucoma who are planning cataract surgery. It may help lower eye pressure when using eye drops is being reduced or stopped.
SantiagoAges 22 years+ - NCT05705024RecruitingPhase 2
Eye drops/treatment to heal stubborn cornea surface damage
This Phase 2 trial tests a locally delivered cell-based treatment (allogeneic mesenchymal stromal cells) to help heal long-lasting damage to the eye’s clear surface (the cornea). It may help if your cornea epithelium (surface layer) won’t improve even after standard non-surgical treatments.
Chicago, IllinoisAges 18 years+
Common questions
- How many eyes & vision clinical trials are recruiting?
- Clin2 is tracking 1,760 recruiting ophthalmology studies from the U.S. registry right now, out of 2,756 we cover in this area in total.
- What does “Eyes & vision” cover here?
- Eye disease and conditions that affect sight. We group each study into eyes & vision based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a eyes & vision trial near me?
- Use the search to filter eyes & vision studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.