Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,609 recruiting studies in this area right now.
By phase
- Not applicable7,632
- Phase 4472
- Phase 2469
- Phase 3439
- Phase 1350
- Phase 1/Phase 2160
- Phase 2/Phase 387
Top conditions
- Stroke797
- Heart Failure534
- Hypertension388
- Cardiovascular Diseases373
- Coronary Artery Disease363
- Multiple Myeloma327
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction97
- Congenital Heart Disease84
- Peripheral Arterial Disease79
- Stroke, Ischemic78
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital68
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California453
- Alabama196
- Arizona181
- Massachusetts173
- New York168
- Florida140
- Texas122
- Maryland118
- Minnesota117
- Illinois112
Recruiting studies9,609 total
- NCT03011697Recruiting
Heart valve disease registry for adults
This study enrolls adults in the hospital with certain heart valve problems to track their health over time. It may help doctors better understand how valve disease behaves and what outcomes look like in real life.
Hangzhou, ZhejiangAges 18 years+ - NCT04300686RecruitingPhase 4
Pilot study for severe Takayasu artery inflammation
This trial studies treatment options for people age 14 and older with severe, active Takayasu arteritis causing major circulation problems and organ strain. It may help reduce inflammation and complications when the disease is flaring and difficult to control.
Shanghai, Shanghai MunicipalityAges 14–100 - NCT04067700Recruiting
Testing a heart scan for reduced blood flow
This study looks at how a special heart imaging test (PET/CT) can show areas with reduced blood flow. It may help doctors understand your heart’s circulation better and guide future care.
KuopioAges 18 years+ - NCT04113356Recruiting
MRI study after first heart attack treated with fast angioplasty
This trial tests how well a heart MRI can be used soon after a first heart attack, especially when a blocked artery is opened quickly with angioplasty. It may help doctors better assess heart injury and guide care after an emergency heart event.
InnsbruckAges 18 years+ - NCT05030259Recruiting
Study of recovery after thigh artery injuries
This trial looks at outcomes in adults who have injuries to the femoropopliteal (thigh-to-knee) artery. It may help doctors understand what affects recovery and discharge, especially for preventing complications.
Shijiazhuang, HebeiAges 18 years+ - NCT03269630Recruiting
Pulmonary hypertension biobank for heart-lung blood samples
This study collects and stores health information and possibly blood samples from people being evaluated for pulmonary hypertension or related autoimmune conditions. It helps researchers learn more about these illnesses and may support future studies.
New Orleans, LouisianaAges 18 years+ - NCT05028686Recruiting
Using blood tests and AI to predict heart failure readmissions
This study looks at hospital and emergency patients with heart failure and uses “omics” (advanced lab data from the body) plus statistics and artificial intelligence to predict who is likely to return to the hospital soon. If it works, it could help doctors better plan follow-up care to reduce repeat hospital visits.
Toronto, OntarioAges 18–105 - NCT05040074Recruiting
Transcatheter repair for leaking mitral valve in high-risk patients
This trial studies a minimally invasive device meant to fix a badly leaking mitral valve (mitral regurgitation) without open-heart surgery. It may be an option if you’re considered too high-risk for standard surgery and your heart anatomy fits the device.
Shenyang, LiaoningAges 18 years+ - NCT03784651Recruiting
How breast cancer treatment changes metabolism and bone
This study looks at how standard breast cancer treatments affect your body’s metabolism and bones in postmenopausal people with early-stage breast cancer. It may help doctors better predict and prevent bone and metabolic side effects from treatment.
Copenhagen, DanmarkAges 50–70 - NCT04253301Recruiting
Testing a vein valve device for chronic venous valve leak
This study tests whether an implanted “vein valve” system can improve blood flow in people with painful chronic venous valve leakage in the thigh/knee veins. It also checks if the procedure and follow-up are safe and workable, especially with blood-thinner medicines before and after.
Nedlands, Western AustraliaAges 18 years+ - NCT03951311Recruiting
Diet and lifestyle study for people with weaker heart pumping
This study looks at how metabolic changes, diet, and lifestyle patterns affect heart failure. It may help find ways to improve symptoms and health by targeting diet and daily habits.
Shanghai, Shanghai MunicipalityAges 14–90 - NCT03313687Recruiting
Safety and outcomes of modern treatments for shock
This study looks at how safe and effective current treatments are for people who have cardiogenic shock, a serious condition when the heart cannot pump enough blood. It mainly aims to understand outcomes from treatment in a hospital setting, which may help improve care for future patients.
HamburgAges 18 years+ - NCT05074732Recruiting
Study of forensic mental health admissions after a service move
This study looks at all adult admissions to Ireland’s National Forensic Mental Health Service during a specific time window. It may help improve how the new forensic service at Portrane runs in the future.
DublinAges 18 years+ - NCT05078814Recruiting
Survey of a heart and leg condition’s gene differences
This study collects information to understand how often certain genetic variants (ALDH gene family) show up in people with blocked leg arteries or an acute heart condition. The results may help researchers better understand the biology behind these illnesses.
TainanAges 20 years+ - NCT05072119Recruiting
Hospital registry to track heart device outcomes
This study keeps a secure record of people who receive a pacemaker, ICD, or implantable loop recorder, to understand how these devices perform over time. If you join, your care team will track your follow-up visits for at least 12 months.
Naples, NapoliAges 14 years+ - NCT04185285Recruiting
Heart procedure registry for people who had stents
This trial is a registry that collects information from people who receive a heart artery procedure (percutaneous coronary intervention) at the study hospital. It mainly helps researchers understand outcomes and care patterns, and it only requires your consent to participate.
FribourgAges 17–120 - NCT05081115Recruiting
Stress echo imaging for people with heart valve or muscle issues
This trial studies a stress echocardiogram (an ultrasound of the heart during stress) to better understand and improve future heart imaging. It may help by comparing how well the test works for different heart conditions.
BeneventoAges 18–75 - NCT03845946Recruiting
CLOUD-R HAE registry for hereditary angioedema patients
This registry study collects information from people with hereditary angioedema (swelling episodes) and related types, with or without a C1-related blood condition. It may help doctors better understand different patterns of swelling and improve future care.
Grenoble, IsereAges Any age - NCT04662294RecruitingEarly Phase 1
CD70-targeted CAR T therapy for CD70-positive blood cancers
This trial tests a customized immune-cell treatment (CAR T) that targets CD70 on cancer cells in certain blood cancers. It may help people whose disease has returned or did not respond to standard treatments.
Hangzhou, ZhejiangAges Any age - NCT04552275RecruitingPhase 1
Biomarker study during valve replacement for older adults
This Phase 1 study looks at changes in the body’s “biomarkers” (measurable signs in blood/medical tests) in older people who are getting a specific type of valve replacement. Results may help doctors better monitor or understand outcomes after this valve procedure.
Boston, MassachusettsAges 65 years+ - NCT05164328Recruiting
Study of heart changes in endurance athletes
This study looks at how the heart can adapt in teens and young adults who do endurance sports. It may help doctors tell the difference between normal training-related heart changes and heart disease.
Melbourne, VictoriaAges 14–23 - NCT04890821Recruiting
Percutaneous ring repair for leaking tricuspid valve
This early study tests a minimally invasive device that helps tighten (repair) the tricuspid valve ring to reduce severe leaking. It may help people who still have symptoms from right-sided heart failure even after taking the best available medicines.
Hackensack, New JerseyAges 18 years+ - NCT03788512Recruiting
Registry study for recent stroke/TIA with heart artery disease
This study enrolls people who recently had an ischemic stroke or a TIA (a “mini-stroke”) and also have evidence of narrowed heart arteries. It collects information to better understand how brain and heart artery disease occur together and may guide future care.
Beijing, BJAges 18–85 - NCT05237817Recruiting
Links stroke history to accidental adrenal gland findings
This study looks at whether certain accidental adrenal gland growths found on scans are linked to having had a stroke. It may help doctors understand stroke risk factors and how adrenal findings should be interpreted.
BeijingAges 18–100
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,609 recruiting cardiology studies from the U.S. registry right now, out of 14,617 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.