Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,613 recruiting studies in this area right now.
By phase
- Not applicable7,634
- Phase 2471
- Phase 4471
- Phase 3438
- Phase 1350
- Phase 1/Phase 2161
- Phase 2/Phase 388
Top conditions
- Stroke796
- Heart Failure535
- Hypertension389
- Cardiovascular Diseases374
- Coronary Artery Disease362
- Multiple Myeloma328
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction96
- Congenital Heart Disease83
- Peripheral Arterial Disease80
- Stroke, Ischemic77
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital67
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California449
- Alabama195
- Arizona182
- Massachusetts174
- New York166
- Florida141
- Texas122
- Maryland118
- Minnesota118
- Illinois111
Recruiting studies9,613 total
- NCT07378137Recruiting
Patient and doctor views on heart treatment outcomes after stenting
This study compares how patients and doctors think about the benefits of heart treatments after a stent procedure. It involves filling out a questionnaire to share your preferences.
Xi'an, ShaanxiAges 18 years+ - NCT07378163Recruiting
Patient and doctor preferences for stent devices
This trial asks patients who have had a stent placed for heart artery disease and their doctors what they prefer in a stent. It aims to understand what factors matter most when choosing a device.
Xi'an, ShannxiAges 18 years+ - NCT07372040RecruitingPhase 2
Adding a Water Pill for Heart Failure in the Hospital
This trial tests if adding a diuretic (water pill) called acetazolamide to usual care can help you get rid of extra fluid faster while you are in the hospital for worsening heart failure.
TantaAges 18 years+ - NCT07372820Recruiting
Metabolic changes after heart transplant and outcomes
This trial looks at how metabolism changes after a heart transplant and whether those changes affect your long-term health and recovery. It is for people who are planning to have or have already had a heart transplant.
Düsseldorf, North Rhine-WestphaliaAges 18 years+ - NCT07373145Recruiting
CT scan check after drug-coated balloon treatment
This trial uses CT scans to see how well a special drug-coated balloon works for opening blocked heart arteries. It may be a good option if you have new blockages that are the right size for this treatment.
SeoulAges 19 years+ - NCT07374263Recruiting
Do heart rhythm drugs pose risks in hospital?
This study looks at whether certain medications that can affect heart rhythm (QT-prolonging drugs) are linked to serious heart problems in adults who were hospitalized. It includes patients admitted to St. Joseph's Healthcare Hamilton or other GEMINI hospitals between 2017 and 2025.
Hamilton, OntarioAges 18 years+ - NCT07376616Recruiting
Heart health study during pregnancy and after birth
This study looks at how the heart adapts during pregnancy and the months after giving birth. It uses simple tests to measure heart rate and blood flow, which may help doctors better understand normal changes and identify risks early.
Vigo, PontevedraAges 18 years+ - NCT07372027Recruiting
Single-needle return for long-lasting dialysis access
This study compares a new single-needle return technique for your dialysis access (AVF) to the usual two-needle method. It aims to see if using just one needle on your fistula and getting the blood back through a leg vein can help your fistula last longer.
Suzhou, AnhuiAges 18–100 - NCT07376590Recruiting
Flow diverter stent study for brain aneurysms
This trial tests a flow-diverting stent for treating certain brain aneurysms located in distal parts of the brain's arteries. It’s for people who have already received this stent and are between 18 and 80 years old.
Hangzhou, ZhejiangAges 18–80 - NCT07371455RecruitingPhase 1
LWP779 safety trial for healthy volunteers
This trial tests a new oral medication called LWP779 in healthy adults to see if it is safe and how the body processes it. It helps determine the right dose for future studies.
AdelaideAges 18–65 - NCT07371624RecruitingPhase 1/Phase 2
Study of B2065 for recent ischemic stroke
This trial tests an investigational drug called B2065 for people who have had a recent ischemic stroke (a stroke caused by a blockage in a blood vessel in the brain). The goal is to see if it is safe and if it might help improve recovery when given within 36 hours of stroke symptoms starting.
BeijingAges 18–75 - NCT07371663RecruitingPhase 1/Phase 2
TCC1727 combination therapy for advanced solid tumors
This trial tests a new drug, TCC1727, combined with other treatments for people with advanced solid tumors that have stopped responding to standard therapy. It aims to see if these combinations can help shrink or control the cancer.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07378956Recruiting
AI eye screening for diabetes patients
This study uses an artificial intelligence (AI) tool to analyze eye images in people with type 2 diabetes. The goal is to see if the AI can help detect early signs of diabetic eye disease, so you can get the right care sooner.
Incheon, Gyeonggi-doAges 19 years+ - NCT06662890Recruiting
Heart attack blood oxygen therapy trial
This trial tests if giving extra oxygen to the blood during a heart attack can help heart muscle recover. It is for people having a specific type of heart attack and balloon treatment.
Clydebank, DunbartonshireAges 18 years+ - NCT06640101Recruiting
Breathing muscle training for stroke recovery
This trial tests whether a simple breathing exercise device can help people recovering from stroke. You may benefit if you had a stroke up to 12 months ago and can walk a short distance on your own.
Shenzhen, None SelectedAges 40–80 - NCT06749834RecruitingPhase 3
Clot-busting drug after stroke in people on newer blood thinners
This trial tests whether a clot-busting medication given through a vein (intravenous thrombolysis) can safely treat acute ischemic stroke within 24 hours in people who have taken a newer oral blood thinner (NOAC) within the last 4 to 48 hours.
Hangzhou, ZhejiangAges 18 years+ - NCT06842940Recruiting
Predicting best lead placement during pacemaker or ICD surgery
This study tests whether a measurement called 'slew rate' can help doctors find the best spot to attach the leads (wires) from a pacemaker or ICD to your heart. It may lead to more stable and effective placement during your procedure.
FidenzaAges 18–100 - NCT04271644RecruitingPhase 1/Phase 2
CAR-T treatment targeting BCMA for hard-to-treat myeloma
This Phase 1/2 study tests a BCMA-targeting CAR-T cell therapy for people with relapsed or refractory multiple myeloma or related plasma cell diseases. It may help by using your own immune cells, engineered to recognize a specific target on cancer cells.
Kunming, YunnanAges 18–75 - NCT04595630Recruiting
Testing heart blood markers to spot early bypass blockage
This study checks whether heart blood tests can predict early blockage of a coronary bypass graft soon after bypass surgery. It may help doctors identify patients at higher risk sooner so they can monitor or treat problems earlier.
ZagrebAges 18 years+ - NCT04776330RecruitingPhase 1/Phase 2
BCMA-targeted CAR-T for relapsed or refractory multiple myeloma
This trial tests a lab-made immune cell therapy (CAR-T) designed to attack a protein called BCMA on myeloma cells. It’s for adults whose multiple myeloma or related plasma cell disease has come back or didn’t respond to prior treatment, aiming to improve cancer control.
Kunming, YunnanAges 18–75 - NCT06224517Recruiting
Artery health after stroke and rehabilitation
This study looks at how well your arteries are working after a stroke and how rehabilitation may help. It uses a simple, painless test (pulse wave velocity) to check artery stiffness.
TaipeiAges 18–80 - NCT05550324Recruiting
Pediatric heart disease patient data repository
This trial is a data repository that collects information from children with heart (cardiovascular) conditions and related syndromes. It focuses on organizing cases and comparing groups to help researchers better understand pediatric heart disease.
Columbus, OhioAges Any age - NCT05942287Recruiting
Weight and weight loss study in heart failure with weak pumping
This study looks at how obesity and weight loss affect people living with heart failure where the heart pumping strength is reduced. It uses heart imaging (MRI) to measure the heart and may help clarify what weight changes do for symptoms and heart function.
Jersey, JerseyAges 18–85 - NCT05908331Recruiting
Balloon treatment test for narrowed stents in heart arteries
This trial tests whether a special drug-coated balloon (“MagicTouch”) can treat re-narrowing inside a previously placed stent. It may help patients whose stent has become blocked again, by improving blood flow and reducing repeat narrowing.
Birmingham, AlabamaAges 18–110
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,613 recruiting cardiology studies from the U.S. registry right now, out of 14,690 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
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- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.