Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,989 recruiting studies in this area right now.
By phase
- Not applicable7,969
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke845
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,986 total
- NCT05164328Recruiting
Study of heart changes in endurance athletes
This study looks at how the heart can adapt in teens and young adults who do endurance sports. It may help doctors tell the difference between normal training-related heart changes and heart disease.
Melbourne, VictoriaAges 14–23 - NCT05165095Recruiting
Remote monitoring checks for new pacemakers
This trial tests how well remote monitoring features in certain pacemakers work after implantation. It may help your care team spot issues earlier and improve the remote alert system.
KremsAges 18 years+ - NCT05166343RecruitingPhase 2/Phase 3
Testing a shot of epinephrine during out-of-hospital CPR
This trial studies whether giving a medicine shot (epinephrine) into the muscle helps children who have a cardiac arrest outside the hospital. It’s meant for emergency situations where CPR is started right away by trained responders.
London, OntarioAges 1 day–17 years - NCT05166954Recruiting
Bariatric surgery and heart function in people with high blood pressure
This study looks at whether bariatric (weight-loss) surgery improves heart function in people who have high blood pressure. You may be able to join if you’re already a bariatric surgery patient at the study hospital and meet the health and medication criteria.
Beijing, Beijing MunicipalityAges 17–70 - NCT05168462RecruitingPhase 4
Lower blood pressure goal in heart-attack shock patients
This study compares two blood pressure targets in people with cardiogenic shock after a heart attack. It looks at whether the lower target can improve outcomes and help evaluate treatment costs.
AmsterdamAges 18 years+ - NCT05167786Recruiting
Electrical spinal cord stimulation for walking after stroke
This trial studies whether a non-surgical electrical treatment to the spinal area can improve walking and leg control after a stroke. It’s for people who have had a single stroke and still need hands-on support to walk.
Chicago, IllinoisAges 18 years+ - NCT05168605Recruiting
Targeted home visits for adults with diabetes and high blood pressure
This study tests whether tailored visits from a care team at your home can improve ongoing health problems from high blood pressure and poorly controlled blood sugar. It may help you by making care easier to follow and more personalized to your daily life.
Dallas, TexasAges 18–60 - NCT05169632Recruiting
Computer brain training for thinking problems after stroke
This trial tests a computerized “cognitive rehabilitation” program aimed at improving executive thinking skills after a stroke. It may help people who still struggle with areas like attention, planning, or mental flexibility.
Lausanne, Canton of VaudAges 18 years+ - NCT05172089Recruiting
Treating recurring infection in diabetic foot ulcers
This trial studies an approach to treat bacteria living in a diabetic foot ulcer and help prevent the ulcer from coming back. You may be able to join if you have an open diabetic foot ulcer and good blood flow to the wound.
Tucson, ArizonaAges 18 years+ - NCT05174052RecruitingPhase 3
Dapagliflozin for heart rhythm problems in diabetes
This trial studies dapagliflozin, a diabetes medicine, to see if it can help people with paroxysmal atrial fibrillation (irregular heart rhythm). If you have both diabetes and this type of AF, the study may offer a chance to improve your heart rhythm and outcomes.
Oklahoma City, OklahomaAges 18–85 - NCT05173740RecruitingPhase 4
Rehab program for people after an out-of-hospital cardiac arrest
This trial studies a rehabilitation program for adults who survived a first out-of-hospital cardiac arrest. It may help improve recovery after leaving the hospital by using guided follow-up and surveys to see how people are doing over time.
CopenhagenAges 18–65 - NCT05174286Recruiting
Phone-based coaching to help prevent colon cancer and heart disease
This study uses community health worker support by phone to help people at higher risk stay on top of recommended screening. It may help reduce colorectal cancer risk and also improve heart health.
New York, New YorkAges 45 years+ - NCT05174442Recruiting
Registry follow-up for Occlutech heart device safety and comfort
This registry follows people who received certain Occlutech heart-related devices to check safety, how well the devices perform, and how easy they are to use. It may help by improving future device safety and user experience based on real-world results.
ErlangenAges Any age - NCT05176132Recruiting
Obesity screening to find hidden weight-related health issues
This study screens adults of different body sizes to find “unrecognized” weight-related health problems. It may help doctors spot issues earlier and understand how common they are across weight groups.
EsbjergAges 18–60 - NCT05178914Recruiting
Testing heart pain treatment guided by blood-flow measurements
This study looks at how to personalize treatment for people with angina (chest pain) by measuring how well blood flows through the heart’s small vessels and the main arteries during a procedure. It may help doctors choose the right approach after your coronary angiography (heart artery imaging).
La TroncheAges 18 years+ - NCT05179473Recruiting
Predict and diagnose stiffness after a recent stroke
This study looks at how to predict and measure spasticity (muscle stiffness and tightness) in people after a recent stroke. It may help clinicians better diagnose and understand what to expect as you recover.
Montreal, QuebecAges 18–85 - NCT05179616Recruiting
Study of TriClip treatment for severe leaky tricuspid valve
This study follows adults with a severely leaky tricuspid heart valve who still have symptoms despite medication. It looks at outcomes after a procedure called TriClip, which helps reduce valve leakage.
PforzheimAges 18 years+ - NCT05179876RecruitingPhase 3
Treatment access study for pulmonary hypertension when no other option
This Phase 3 study continues treatment for people with pulmonary hypertension who finished an earlier parent study and have no other approved treatment option. It tests whether continuing their current medicine can help them keep getting benefit and stay safe.
MinskAges 2 years+ - NCT05180942Recruiting
Statins and heart plaque changes in people with melanoma on immunotherapy
This trial studies whether taking a cholesterol medicine called a statin can slow the buildup or worsening of coronary artery plaque in people with melanoma who are receiving checkpoint inhibitor (immunotherapy) treatment. It mainly looks at heart scans over time to see if statins change the progression of coronary atherosclerosis.
Kingswood, New South WalesAges 40 years+ - NCT05180786Recruiting
Brain-training therapy to improve arm movement after stroke
This study tests a learning-and-recovery approach meant to help people regain arm and hand control after a long-term stroke. It targets patients with specific movement and brain-connection patterns so the training can be safely done.
Chicago, IllinoisAges 18 years+ - NCT05185492Recruiting
Registry for treatment outcomes in cardiogenic shock
This trial is a registry that collects information about people with cardiogenic shock to better understand outcomes and improve management. It may help by contributing real-world data on what treatments and timing work best for different heart-related shock causes.
Weston, FloridaAges 18 years+ - NCT05183672Recruiting
Phone-based check-ins after stroke using a nurse clinic
This trial tests whether nurse-led telecare (phone/video check-ins) can improve follow-up care after a recent stroke. It may help you get timely support from home rather than frequent in-person visits.
KowloonAges 18 years+ - NCT05183763Recruiting
Program to help improve blood pressure medication use
This trial tests a medication adherence program to help people with high blood pressure take their blood pressure medicines more reliably. It may help lower blood pressure by improving refill timing and daily medication use.
Baton Rouge, LouisianaAges 40 years+ - NCT05184790Recruiting
Using imaging during radiation therapy to improve AI planning
This study tests how well an artificial intelligence system can use special X-ray images taken during certain radiation treatments to improve care. You may qualify if you’re having radiation for specific conditions and your treatment center uses the required imaging steps.
Saint Leonards, New South WalesAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,989 recruiting cardiology studies from the U.S. registry right now, out of 15,300 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.