Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,989 recruiting studies in this area right now.
By phase
- Not applicable7,969
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke845
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,986 total
- NCT05184933Recruiting
Study sleep timing and blood pressure patterns in adults
This study looks at how your sleep schedule and body clock relate to blood pressure control. You may be asked to follow a study plan that helps researchers understand what sleep and daily timing changes do to hypertension.
Portland, OregonAges 25–64 - NCT05189860Recruiting
C-MIC system follow-up visits study
This study checks on people who previously received a C-MIC System, usually by asking them to come in for follow-up visits. It helps the team learn how the system is doing over time and supports better care planning.
Banja Luka, Banja LukaAges 18–75 - NCT05190653Recruiting
Support during stem cell or CAR T cancer treatment
This study tests whether starting palliative and supportive care early (alongside cancer treatment) can improve comfort and support for people having stem cell transplant or CAR T-cell therapy. It may also help family caregivers by offering support during a difficult treatment period.
Calgary, AlbertaAges 18 years+ - NCT05190718Recruiting
Pharyngeal electrical stimulation for swallowing trouble after brain injury
This trial tests a non-drug therapy that uses gentle electrical stimulation to help people swallow safely when swallowing is affected by certain brain or nerve conditions. If you qualify, you may receive this approach to improve swallowing and reduce choking risk.
Tulln, Low AustriaAges 18 years+ - NCT05192122RecruitingPhase 1
Stop maintenance medicine in multiple myeloma with low remaining disease
This early-phase study looks at whether it’s safe to stop the usual “maintenance” medicine after a strong response in multiple myeloma. It aims to see if stopping treatment for people with very low remaining disease reduces drug exposure without allowing relapse too soon.
Chicago, IllinoisAges 18 years+ - NCT05193396RecruitingPhase 4
Hydrocortisone trial for adrenal symptoms after stopping steroid pills
This trial tests whether hydrocortisone (a cortisol replacement) helps people who feel symptoms of adrenal insufficiency after they stop long-term prednisolone. It compares hydrocortisone versus placebo to see if symptoms improve and dosing is safer/effective.
AarhusAges 50 years+ - NCT05194423Recruiting
LuX-Valve procedure for severe leaking tricuspid valve
This trial tests a minimally invasive procedure (LuX-Valve placed through a neck vein) to treat severe leaking of the tricuspid valve. It may help people who are too high-risk for open-heart tricuspid surgery.
Beijing, Beijing MunicipalityAges 50 years+ - NCT05195658Recruiting
Stent vs standard treatment for acute carotid artery stroke
This trial studies whether placing a special device (a micronet-covered stent) can improve treatment of certain acute strokes caused by blockage at the carotid artery “bifurcation” (where the artery splits). It is meant for people who need an urgent, catheter-based procedure to open the blocked vessel.
KrakowAges 18 years+ - NCT05195905Recruiting
Endograft study for complex thoracoabdominal or pararenal aneurysms
This trial tests a specialized endograft (a fabric tube placed inside the artery) for repairing large aneurysms near the kidneys and intestines. It may help people whose aneurysm anatomy would make standard grafts too short or poorly sealed, but you must meet specific artery size, location, and heart/kidney safety requirements.
Tampa, FloridaAges 18 years+ - NCT05198791RecruitingPhase 2
Eplerenone for heart injury without blocked heart arteries
This Phase 2 study tests whether eplerenone can improve outcomes after a heart attack (or similar heart injury) when coronary angiography shows no blocked heart arteries. It focuses on people with added cardiovascular risk factors and evaluates how well the treatment works for heart recovery and strain on the heart.
East Kilbride, LanarkshireAges 18 years+ - NCT05199194RecruitingPhase 3
Clot-busting before or during procedure for acute stroke
This study compares two treatment approaches for a stroke caused by a blocked brain artery: doing a procedure to remove the clot alone versus giving an IV clot-busting medicine first (tenecteplase). It aims to see which approach works better and is safest for improving recovery.
Porto Alegre, Rio Grande do SulAges 18–85 - NCT05198960RecruitingPhase 3
Blood thinner drugs vs aspirin to prevent clot problems
This trial compares apixaban or rivaroxaban (blood thinners) against aspirin to prevent future clot-related complications in people with certain bone marrow diseases (PV, ET, or pre-PMF) that have a specific JAK2 mutation. It may help lower the risk of clots, but it also carefully considers bleeding risk.
AngersAges 18 years+ - NCT05199454Recruiting
Study how “fat-like” particles affect blood vessel function
This study looks at whether tiny fat-based particles (“adiposomes”) can affect how well your blood vessels work, especially in people with diabetes and higher body weight. You may be asked to do moderate exercise and other study procedures after passing safety checks.
Chicago, IllinoisAges 18–50 - NCT05199662RecruitingPhase 3
IV clot-busting medicine for stroke when standard options don’t fit
This trial tests whether giving IV TNK (tenecteplase) plus standard stroke care can improve outcomes in some people who have a new stroke but cannot get alteplase (another clot-busting drug) and do not have a large blocked artery that can be treated with a procedure. It’s meant for strokes with “mismatch” findings on scans that suggest salvageable brain tissue.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT05201144RecruitingPhase 2
Test of sildenafil after diaphragm hernia surgery in newborns
This trial studies whether sildenafil (a medicine that helps relax blood vessels) can improve outcomes in babies born with a congenital diaphragmatic hernia (CDH) after they’ve had surgery. Babies are selected based on an ultrasound/echo of heart function after repair.
Salt Lake City, UtahAges Any age - NCT05200715Recruiting
Registry study for inherited and inflammatory eye and joint diseases
This study is a registry, meaning it collects your medical information to better understand several inflammatory (auto-inflammatory) conditions. It may help doctors and researchers improve diagnosis and future treatments for people with these disorders.
AlgiersAges Any age - NCT05202210Recruiting
Biobank study for people with Noonan syndrome
This study collects biological samples to better understand what causes Noonan syndrome. If you qualify, your participation could help researchers learn how the condition works and guide future care.
ToulouseAges 18–99 - NCT05201781RecruitingPhase 4
Long-term follow-up for people previously treated with cilta-cel
This study follows people over time who previously received cilta-cel in a Janssen-sponsored clinical trial. It helps doctors learn about how well the treatment works and how safe it is in the long run.
Phoenix, ArizonaAges 18 years+ - NCT05203003Recruiting
Testing whether measurable cancer leftovers predict outcomes
This study looks at whether small leftover signs of multiple myeloma in blood or bone marrow (called measurable residual disease, or MRD) can predict how well treatment works. It involves people already taking study treatment in a larger trial and checks results about two years later to see who benefits most.
ParisAges 18 years+ - NCT05204693Recruiting
Left-heart patients on stable meds will do study cycling
This trial studies a “cycling instead of pushing” approach for people with left-heart disease who are stable on their heart medicine. The goal is to see if this training/therapy approach is safe and helpful for patients like you.
Zurich, Canton of ZurichAges 18–80 - NCT05206838Recruiting
Treating gluteus medius tendon weakness after hip replacement
This trial looks at treating a specific hip muscle-tendon problem (gluteus medius insufficiency) after total hip replacement. It may help people who have had ongoing limping despite surgery by using an Achilles tendon–based approach.
MölndalAges 40–80 - NCT05208567Recruiting
Testing heart ultrasound in older adults with weak heart pumping
This trial uses a heart ultrasound test to find people who may have weak heart pumping function, especially in a multi-ethnic community. It may help improve how doctors detect this condition earlier using ultrasound images.
LondonAges 65 years+ - NCT05208203Recruiting
Registry study for recent stroke and mini-stroke patients
This registry collects information about people recently diagnosed with an acute ischemic stroke or a transient ischemic attack (TIA) at a specific hospital. It helps doctors understand patterns of care and outcomes, which can improve future treatment planning.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05208749Recruiting
Shockwave or rotablation for calcified heart artery blockages
This study tests two ways to treat tightly calcified coronary (heart) artery blockages during a procedure to open the vessel. It may help improve how well the blockage can be widened and treated when standard balloon treatment is not enough.
Leuven, BrabantAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,989 recruiting cardiology studies from the U.S. registry right now, out of 15,300 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.