Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,613 recruiting studies in this area right now.
By phase
- Not applicable7,634
- Phase 2471
- Phase 4471
- Phase 3438
- Phase 1350
- Phase 1/Phase 2161
- Phase 2/Phase 388
Top conditions
- Stroke796
- Heart Failure535
- Hypertension389
- Cardiovascular Diseases374
- Coronary Artery Disease362
- Multiple Myeloma328
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction96
- Congenital Heart Disease83
- Peripheral Arterial Disease80
- Stroke, Ischemic77
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital67
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California449
- Alabama195
- Arizona182
- Massachusetts174
- New York166
- Florida141
- Texas122
- Maryland118
- Minnesota118
- Illinois111
Recruiting studies9,613 total
- NCT05866640RecruitingEarly Phase 1
Testing a filter to reduce debris during TAVR
This early feasibility study tests a device filter system used during a TAVR procedure to help protect the brain and other organs from debris that can break free. It looks mainly at whether the filter can be safely placed and delivered as planned.
TbilisiAges 22 years+ - NCT06490276Recruiting
Biofeedback gait training for stroke survivors
This study tests whether a special gait training program with biofeedback (real-time information about your walking) can improve walking quality in people who have had a stroke. It may help you walk better and more naturally.
TaipeiAges 20–80 - NCT06504836Recruiting
Walking feedback in stroke recovery
This study tests a special walking feedback system (like a video game for your legs) for people who had a stroke at least 6 months ago. It aims to improve walking quality, such as how smoothly and evenly you step.
TaipeiAges 20–80 - NCT07366879Recruiting
Exercise program for newly diagnosed pulmonary hypertension
This study tests whether a home-based exercise program, added to your regular medications, can help people who are newly diagnosed with pulmonary arterial hypertension feel better and improve their daily function.
GlasgowAges 18 years+ - NCT07367724RecruitingPhase 2
Ademetionine for obstructive hypertrophic cardiomyopathy
This trial tests a medication called Ademetionine for people with obstructive hypertrophic cardiomyopathy (a condition where the heart muscle is thick and blocks blood flow). It aims to see if the drug can help improve symptoms and exercise ability.
BeijingAges 18 years+ - NCT07362134Enrolling by invitation
Pulsed-field ablation for recurrent atypical atrial flutter
This study tests a new type of energy called pulsed-field ablation (PFA) to treat a specific kind of irregular heartbeat called atypical atrial flutter that keeps coming back after a prior ablation. It aims to see if this approach can safely stop the abnormal rhythm.
TaipeiAges 18–80 - NCT06818474RecruitingPhase 4
Lanadelumab to prevent acquired angioedema attacks
This trial tests if lanadelumab can prevent swelling attacks in people with acquired angioedema (AAE). Acquired angioedema is a rare condition that causes sudden swelling in the skin and other body parts. This medicine is given as a long-term shot to lower the number of attacks you have.
Cincinnati, OhioAges 18 years+ - NCT06844942Recruiting
Improving heart artery imaging for chest pain diagnosis
This trial uses a special camera called OCT to take detailed pictures of the heart's arteries. It aims to see if these pictures help doctors better understand blockages and decide on treatment for stable chest pain.
Warsaw, Mazowieckie VoivodenshipAges 18 years+ - NCT07370103Recruiting
Predicting low blood pressure in liver disease patients after anesthesia
This study uses an ultrasound to measure blood flow in the neck's main artery to see if it can predict a dangerous drop in blood pressure after you are put to sleep for surgery. It is for adult patients with chronic liver disease who are having planned surgery.
CairoAges 18 years+ - NCT07363525Recruiting
Early experience with Tigertriever for stroke clot removal
This study looks at the early experience using the Tigertriever device to remove blood clots from large arteries in the brain. It may help researchers understand how well the device works in real-life practice for people having a stroke.
Detroit, MichiganAges 18 years+ - NCT07368322Recruiting
Y-incision vs. standard surgery for aortic root enlargement
This study tests a new surgical method (Y-incision) to enlarge the aortic root during valve replacement, which may help people with a small valve opening. It compares this technique to standard approaches to see if it can prevent the new valve from being too small.
HaifaAges 18–80 - NCT07363772Recruiting
Mixed reality CPR training for adults
This trial tests whether mixed reality (a blend of real and virtual worlds) can teach cardiopulmonary resuscitation (CPR) to adults. It may help people who haven't taken a CPR class in the last year learn this lifesaving skill in a new way.
Seoul, Nowon-guAges 18–50 - NCT07370688RecruitingPhase 4
Iron infusion after TAVI for older adults
This trial tests whether giving iron infusions after a TAVI procedure can help patients with iron deficiency feel better and improve their quality of life. It is for older adults who have low iron levels and have already had a successful valve replacement.
Rotterdam, South HollandAges 65 years+ - NCT07363993Recruiting
Heart flow and pumping in athletes vs. non-athletes
This study uses 3D ultrasound to see how the heart moves blood in people who exercise a lot versus those who do not. It could help understand how regular endurance training changes heart function.
AvignonAges 18–45 - NCT07365501Enrolling by invitation
Blood pressure cuff therapy for heart failure patients
This trial tests if a simple, non-invasive blood pressure cuff procedure can improve blood vessel health in people with possible heart failure. It is an early, single-session study to see how the body responds.
Cuenca, CuencaAges 18 years+ - NCT07368062Recruiting
Mental health after a heart rhythm drug in the ICU
This study looks at the long-term mental health of people who received a drug called dexmedetomidine during an electrical storm (a dangerous heart rhythm) in the ICU.
Ottawa, OntarioAges Any age - NCT07366684Recruiting
Heart attack study for adults 75 and older
This study looks at how frailty and other health factors affect recovery in people 75 and older who have had a heart attack or unstable chest pain. It may help doctors better understand who is at higher risk and how to improve care for older adults.
NišAges 75 years+ - NCT07363278Recruiting
Study of a new device for atrial fibrillation ablation
This study looks at how often silent brain lesions happen after a new type of heart procedure for atrial fibrillation (an irregular heartbeat). The procedure uses a device called the Varipulse catheter to help fix the heart's rhythm.
Seoul, Jongro-kuAges 19 years+ - NCT07365345Recruiting
Electrical Stimulation for Low Blood Pressure During TAVR
This study tests whether electrical stimulation at specific points on the body can help prevent low blood pressure during TAVR, a minimally invasive heart valve procedure. It may help people who are at risk for blood pressure drops during surgery.
Xi'an, ShannxiAges 60 years+ - NCT07361887Recruiting
Moderate wine and healthy aging study
This study tests whether moderate wine consumption can help healthy aging by looking at tiny particles in your blood after a meal. It may help you understand how wine affects your body's cells.
Seville, SevillaAges 35–36 - NCT07361861Recruiting
Hyperbaric oxygen for fitness and inflammation in healthy adults
This trial is testing whether breathing pure oxygen in a pressurized chamber (called hyperbaric oxygen therapy) can improve your fitness and lower inflammation. You may qualify if you’re a healthy, active adult aged 30–60.
Austin, TexasAges 30–60 - NCT07369765Recruiting
Balloon vs stent for blocked arteries
This trial compares two procedures to open completely blocked coronary arteries: a drug-coated balloon or a drug-eluting stent. It may help patients with a single, medium-length blockage in a large enough artery.
IstanbulAges Any age - NCT07363538Recruiting
Comparing heart surgery methods for newborns with complex heart defects
This trial tests new surgical strategies for newborns with certain complex heart conditions. It aims to see which techniques lead to better recovery and quality of life in the first year after surgery.
Beijing, Beijing MunicipalityAges Up to 1 week - NCT07364175Recruiting
Weight loss drug study for young adults with high blood pressure
This trial tests if the weight loss medication tirzepatide can help young adults (18–40) with obesity and high blood pressure lower their blood pressure. It compares standard care to weight loss with tirzepatide.
Cambridge, CambridgeshireAges 18–40
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,613 recruiting cardiology studies from the U.S. registry right now, out of 14,690 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.