Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,989 recruiting studies in this area right now.
By phase
- Not applicable7,969
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke845
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,986 total
- NCT05365425RecruitingPhase 4
Choline fenofibrate to reduce plaque in type 2 diabetes
This trial studies whether choline fenofibrate can improve blood vessel plaque (carotid artery plaque) in people with type 2 diabetes and mixed cholesterol problems. It aims to see if the medicine can make carotid plaque thinner or otherwise healthier while keeping safety in mind.
Seongnam-si, Gyeonggi-doAges 20 years+ - NCT05366452Recruiting
Early heart pump implant for shock after a heart attack
This trial studies whether putting in a small heart pump early (through the leg) helps people with a heart attack complicated by severe heart weakness (“cardiogenic shock”) compared with standard treatment. It aims to improve survival and recovery by supporting blood flow sooner.
Marseille, Bouche DU RhoneAges 18–80 - NCT05366153Recruiting
Plan to lower future heart attack risk after past cancer treatment
This trial tests whether a “risk-guided” care plan can help prevent coronary artery disease (the buildup that can lead to heart attacks) in people who had cancer treatment that can affect the heart. You may get closer heart risk monitoring and guidance to reduce risk factors, such as cholesterol—especially if you can safely take statins.
Hobart, TasmaniaAges 40–70 - NCT05366361Recruiting
Study of persistent atrial fibrillation during heart procedures
This study looks at what happens in the heart in people with persistent atrial fibrillation when they undergo an ablation or Maze surgery. It may help doctors better understand the condition and improve future care for people needing these procedures.
Stanford, CaliforniaAges 22–80 - NCT05367037Recruiting
Heart pacing strategy to help prevent ongoing atrial fibrillation
This trial compares two heart pacing approaches to see which one better helps prevent atrial fibrillation (an abnormal heart rhythm). It is for people who need a pacemaker and have a prolonged delay between the upper and lower heart chambers.
Rovigo, VenetoAges 18 years+ - NCT05366881Recruiting
Blood test study to spot early cancer signal and cancer leftovers
This observational study checks whether a blood test (a “cfDNA” test) can detect early signs of cancer or small amounts of cancer left after treatment. It may help doctors use a simple blood sample to improve cancer detection and follow-up.
Duarte, CaliforniaAges 40 years+ - NCT05367297Recruiting
Registry study of heart plaque in South Asian adults
This study tracks coronary plaque (fatty deposits in heart arteries) in South Asian adults and compares them with people of other backgrounds. You may be asked to have a special heart CT scan and basic measurements to help researchers understand differences in heart disease risk.
Dallas, TexasAges 18 years+ - NCT05369195Recruiting
Protecting the brain during a heart procedure for atrial fibrillation
This trial studies a way to help protect the brain during a catheter procedure that closes the left atrial appendage (a small heart pouch) in people with atrial fibrillation. It may help lower the risk of stroke-related brain injury for patients who can’t safely take blood thinners.
KatowiceAges 18 years+ - NCT05369065RecruitingPhase 1
Artery ablation for type 2 diabetes with kidney and liver arteries
This Phase 1 study tests whether a minimally invasive artery procedure can improve type 2 diabetes and related health problems by targeting kidney and liver blood vessels. Because it’s early-stage, the main goal is safety and learning how the treatment works in people who meet specific diabetes, blood pressure, and blood test requirements.
TbilisiAges 21–65 - NCT05369351RecruitingPhase 2
Mirabegron for brain bleeding soon after symptoms start
This trial studies whether mirabegron can improve safety and outcomes after an intracerebral hemorrhage (a type of brain bleeding). Participants start treatment within 72 hours of symptom onset and are monitored for recovery and side effects.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT05369442Recruiting
Blood-thinner plan study for people with high bleeding risk after PCI
This trial studies which blood-thinner (antiplatelet) strategy is safest and most effective for people at high risk of bleeding after a procedure called PCI. It also looks at longer-term outcomes and whether adjusting treatment can improve safety without losing heart protection.
Sichuan, SichuanAges Any age - NCT05370014Recruiting
Study for COVID survivors and their unpaid carepartners in South Carolina
This study looks at how to improve health and support for African American adults who had COVID-19 severe enough to need urgent care or hospitalization, along with the unpaid carepartner who helps them at home. It may be helpful if you and your carepartner live in a medically underserved or rural area and share daily support needs.
Columbia, South CarolinaAges 18 years+ - NCT05369520Recruiting
Noninvasive spinal stimulation to improve bladder and autonomic function
This trial tests a noninvasive way to stimulate the spinal cord to help the body’s “automatic functions” (like bladder, bowel, and sexual function) after spinal cord injury. If you’ve had a stable, complete spinal cord injury for more than a year, you may be eligible to try this approach and help researchers evaluate recovery.
Vancouver, British ColumbiaAges 19–60 - NCT05371405Recruiting
Using computer learning to improve care for atrial fibrillation patients
This study uses machine learning (computer pattern-finding) to better understand atrial fibrillation and guide care around the time of an ablation procedure. It may help refine how doctors treat certain AF patients based on their heart patterns.
Stanford, CaliforniaAges 22–80 - NCT05371145RecruitingPhase 1/Phase 2
Carnosine study for people with blocked leg arteries
This Phase 1/2 study tests whether L-carnosine can improve symptoms or circulation in people with peripheral arterial disease (blocked arteries in the legs). You may be able to join if you’re in the right age range and have specific test results showing moderate artery blockage.
Louisville, KentuckyAges 50–80 - NCT05372354RecruitingPhase 1/Phase 2
Testing a new multiple myeloma drug with other treatments
This early-phase study tests how safe a new drug (CC-92480) is and how much it stays in the body, when given with other standard or study treatments. It’s for people whose multiple myeloma has come back or did not respond after prior therapy, with the goal of improving disease control.
Birmingham, AlabamaAges 18 years+ - NCT05372718RecruitingPhase 3
Clot-busting drug versus surgery for sudden blocked leg arteries
This trial compares a clot-busting medicine (staphylokinase) against surgery in people with sudden, dangerous reduced blood flow to a leg. It may help find a safer or more effective way to restore circulation and prevent limb complications.
Kursk, Kursl RegionAges 18 years+ - NCT05372263Recruiting
Tracking safety of pulmonary hypertension medicines by computer follow-up
This study checks how safe pulmonary hypertension–targeted medicines (and some calcium-blocking medicines) are over time. It uses a computer system to follow you after diagnosis, looking at outcomes and side effects.
Beijing, Beijing MunicipalityAges 3 months–85 years - NCT05373940Recruiting
ICD placement to prevent sudden heart death in people over 70
This study looks at placing an ICD, a device that can stop dangerous heart rhythms, to help prevent sudden cardiac death. It is for people over 70 with specific heart function and heart failure symptoms.
Aix-en-ProvenceAges 70 years+ - NCT05373498Recruiting
Registry for children’s heart emergencies after resuscitation
This trial is a registry that collects information about children (under 18) who have congenital heart problems and need resuscitation with chest compressions. It helps doctors understand these emergencies and may improve future care for similar patients.
Leipzig, SaxonyAges Up to 18 years - NCT05374681Recruiting
Test a minimally invasive add-on treatment for brain vessel swelling
This trial studies whether an add-on, minimally invasive procedure works better than standard care for a specific brain blood-vessel problem (CSH) that is larger than 10 mm. It may help reduce symptoms or prevent worsening, if you meet the size and location requirements.
Amiens, FranceAges 18 years+ - NCT05375292Recruiting
Pre-surgery fitness program for recovery after aneurysm surgery
This study tests whether a supervised “prehabilitation” program before planned open surgery helps you recover better after abdominal aortic aneurysm surgery. It’s mainly about improving outcomes when you have time to prepare for at least 6 weeks.
ToulouseAges 18–100 - NCT05375149Recruiting
Breath particle study after lung transplant
This study looks at tiny particles in exhaled breath after a lung transplant. It may help researchers understand how the lungs are doing after transplant by using breath samples.
Lund, Skåne CountyAges 16–75 - NCT05376254Recruiting
3D heart scan study during LVAD implantation
This study uses special 3D heart imaging to better measure right-heart function during LVAD surgery. It may help doctors understand how the right side of the heart responds when a mechanical pump is put in.
Edmonton, AlbertaAges 16 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,989 recruiting cardiology studies from the U.S. registry right now, out of 15,300 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.