Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,989 recruiting studies in this area right now.
By phase
- Not applicable7,969
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke845
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,986 total
- NCT05377216RecruitingEarly Phase 1
Testing nerve stimulation effects during heart ablation
This trial studies how a type of nerve stimulation affects the heart’s electrical signals during a procedure to treat a dangerous fast heart rhythm (ventricular tachycardia). It may help doctors better understand safety and effects during planned ablation.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05378308Recruiting
Tracking blood thinner use in people with AF or blood clots
This registry study looks at how people with atrial fibrillation (AF) or blood clots (VTE) use blood thinners, especially NOACs, over time. It may help doctors better understand real-world patterns of treatment and outcomes.
Zhengzhou, HenanAges Any age - NCT05378035Recruiting
DOAC interruption study for Chinese people with atrial fibrillation
This trial studies how safely and effectively to pause a blood thinner (a DOAC) for about 48 hours before an elective procedure in people with atrial fibrillation. It may help confirm the best way to reduce bleeding risk without raising stroke risk.
Hong KongAges 18–80 - NCT05378347Recruiting
Compare two aortic stent graft types for AAA
This study compares two commercially used stent graft devices to treat an enlarged abdominal aorta (AAA). It aims to see which device works better and is safer over follow-up visits.
Loma Linda, CaliforniaAges 20 years+ - NCT05378139Recruiting
At-home and hospital wireless monitoring for worsening health
This trial tests a system that continuously checks vital signs (like heart rate and breathing) using wireless sensors and sends automatic alerts if you seem to be getting worse. It may help clinicians spot problems sooner whether you’re being monitored at home or around a major surgery hospital stay.
Copenhagen, CopenhagenAges 18 years+ - NCT05378490Recruiting
Study of stroke types and thrombolysis treatment
This study includes people who have had certain kinds of sudden brain blood-flow problems (like an ischemic stroke, bleeding in the brain, or a brief warning episode) or conditions that look similar. It looks at how treatment such as clot-busting medicine (thrombolysis) fits for these situations.
LørenskogAges 18 years+ - NCT05380622Recruiting
CT scan to study plaque and blood flow in heart disease
This study uses a special heart CT scan (coronary CT angiography) to look at plaque and how blood flows in people with coronary artery disease. It may help match your scan results with heart measurements and guide future care decisions.
ShanghaiAges 18 years+ - NCT05383339Recruiting
Testing blood markers in autoimmune, vasculitis, and autoinflammation
This study looks at blood “biomarkers,” or measurable body signals, in people with autoimmune diseases, vasculitis, or autoinflammatory conditions. The goal is to better understand these illnesses and how they relate to disease activity.
Paris, FranceAges 18 years+ - NCT05386173Recruiting
Tests fetal aortic valve balloon surgery for severe narrowing
This trial studies whether doing a procedure before birth to open a baby’s aortic valve improves outcomes. It compares this approach in a specific group of pregnancies with severe heart flow problems seen on ultrasound.
San Francisco, CaliforniaAges 5 months–7 months - NCT05386342Recruiting
Study of a catheter used to remove blood clots
This study looks at whether a specific over-the-wire catheter (TufTex) is safe and works well when doctors remove blood clots (embolus/thrombus) during surgery. You might join if you’re having a planned clot-removal procedure and other clot-dissolving medicines have not worked or can’t be used.
BrandenburgAges 18 years+ - NCT05387954RecruitingPhase 3
PFO closure or blood thinners after stroke in ages 60–80
This trial studies the best way to prevent another stroke after a recent stroke in people ages 60 to 80 who have a “PFO” heart connection. It compares closing the PFO vs taking mouth blood-thinners or antiplatelet medicine, based on what your doctors determine is safest for you.
AmiensAges 60–80 - NCT05388097Recruiting
Quality program to reduce hospital readmissions for heart failure
This trial tests whether a new hospital “quality improvement” program can lower the chances of coming back to the hospital after being admitted for acute heart failure. It focuses on social needs (like resources and support) that can affect recovery and readmissions.
Olathe, KansasAges 18–99 - NCT05388032Recruiting
Test whether lowering salt improves blood vessel health
This trial studies whether a lower-salt plan can improve how your blood vessels work. It’s meant for adults with higher blood pressure who may be at risk for heart and blood vessel problems.
New Orleans, LouisianaAges 40 years+ - NCT05389878Recruiting
Stroke patient registry for people within 6 months of stroke
This trial sets up a registry (a secure database) to better track and understand adults who have had an ischemic or hemorrhagic stroke within the last 6 months. Being listed may help researchers learn what care works best for different types and stages of stroke.
FlorenceAges 18 years+ - NCT05390047Recruiting
Register people with an S-ICD and follow them after implant
This trial is a registry that collects real-world information from people who receive an S-ICD (a small device under the skin) to help doctors learn how these devices perform over time. You may qualify if you already had the implant and can be followed for at least one month.
Lübeck, Schleswig-HolsteinAges 18–99 - NCT05389956Recruiting
Study links health screening results to heart and cancer risk
This study follows people who had a routine health check to learn what increases the risk of heart disease and cancer. Your answers and test results may help doctors better understand risk factors in the Korean population.
UlsanAges 19 years+ - NCT05391815Recruiting
Observational study of endovascular treatment for blocked leg arteries
This is a real-world observational study that follows people who get minimally invasive procedures to treat blocked arteries in the lower abdomen and pelvis. It aims to understand how well these treatments work in the middle and long term.
ShanghaiAges 18–80 - NCT05393492Recruiting
Emotion and behavior skills after a brain injury
This study tests a structured program to help people after a brain injury manage emotions and challenging behaviors, and to reduce distress for them and their families. If you (or your family member) can participate safely and understand the activities in French, you may be invited to join a group and assessments.
Illkirch-GraffenstadenAges 18 years+ - NCT05394506Recruiting
Study of factors that affect muscle laminopathy with LMNA changes
This study looks at what influences the course of a muscle disease caused by an LMNA genetic change (a type of laminopathy). It may help researchers better understand the disease and how it affects muscle and sometimes breathing or heart function.
Bron, Auvergne-Rhône-AlpesAges 2 years+ - NCT05395598Recruiting
Long-term follow-up for large aortic root aneurysm risks
This study follows people with an enlarged aortic root to track how often serious complications happen over time. It may help doctors understand risk and improve care by observing outcomes for up to five years.
Lille, Please Choose...Ages 45–80 - NCT05397392Recruiting
Diagnosis and treatment plan for heart–kidney problems
This study looks at the best way to diagnose and treat different types of heart-and-kidney problems that happen together. It may help you (or your caregiver) get the right classification and treatment approach based on how your heart and kidneys are affected.
NanjingAges 18 years+ - NCT05397405Recruiting
Improving cholesterol control after narrowing in brain arteries
This study looks at strategies to improve cholesterol treatment in adults whose brain arteries are narrowed and who have had symptoms. Better cholesterol management may help reduce future problems related to this condition.
Nanjing, JiangsuAges 18–85 - NCT05397873Recruiting
Biofeedback training to improve vision in hemianopia
This trial tests whether guided “biofeedback” training can help people with hemianopia (a vision field loss) improve how they use their remaining vision. You may be asked to complete vision testing and practice exercises while receiving feedback based on your responses.
Toronto, OntarioAges 18–90 - NCT05398679RecruitingPhase 4
Oral antibiotics versus IV antibiotics after heart infection
This trial compares taking antibiotics by mouth versus receiving antibiotics through a vein (outpatient IV) for an infection of the heart valve. It’s designed to see whether the oral option can work as well and safely, especially after initial treatment and surgery if needed.
Alicante, AlicanteAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,989 recruiting cardiology studies from the U.S. registry right now, out of 15,300 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.