Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,989 recruiting studies in this area right now.
By phase
- Not applicable7,969
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke845
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,986 total
- NCT05551104RecruitingPhase 3
Best blood pressure medicine after pregnancy
This study compares two common blood pressure medicines (nifedipine and labetalol) to see which is safest and works best for high blood pressure after childbirth. If you have postpartum hypertension, the trial may offer close monitoring and help doctors choose the safest option for you.
Loma Linda, CaliforniaAges 18 years+ - NCT05552222RecruitingPhase 3
New treatment combo study for newly diagnosed multiple myeloma
This phase 3 trial tests two different drug combinations to treat newly diagnosed multiple myeloma. It may help by aiming to control the cancer without using high-dose chemotherapy and stem cell transplant for people who can’t receive that approach.
Gilbert, ArizonaAges 18 years+ - NCT05552352Recruiting
VR training to help people prepare for aortic valve procedure
This trial tests whether virtual reality (VR) support helps patients feel more informed and prepared for an elective heart valve procedure (TAVI). It’s meant for people who already plan to have a valve replacement through the groin using a catheter, with pain medicines rather than full anesthesia.
Düsseldorf, North Rhine-WestphaliaAges 18 years+ - NCT05552547Recruiting
Home blood pressure monitoring for African American adults
This study looks at how checking blood pressure at home works for preventing or spotting high blood pressure early in African American participants. It may help you learn more about your blood pressure patterns over time.
Cleveland, OhioAges 13–18 - NCT05553223Recruiting
Very small activity doses for COPD symptoms
This study tests whether “micro-doses” of physical activity (short, small amounts) can help people with COPD. It aims to see if these small activity bursts are safe and beneficial for people who have stable COPD.
Kelowna, British ColumbiaAges Any age - NCT05554588Recruiting
Thrombus-finding treatments for heart attack during angioplasty
This trial compares two ways to remove or break up a blood clot during emergency heart artery opening (primary PCI) for a specific type of heart attack (STEMI). It may help patients with a high clot burden by testing whether one approach works better than the other to improve outcomes.
Beijing, Beijing MunicipalityAges 18–80 - NCT05555095Recruiting
Digital care programs for people on Medicaid
This trial tests a digital (phone or online) model for delivering healthcare for people who have Medicaid or qualify for both Medicare and Medicaid. It may help improve how care is organized and delivered for conditions like high blood pressure, diabetes, or pregnancy.
Peoria, IllinoisAges 18 years+ - NCT05556369Recruiting
Genetic testing study for heart muscle disease in families
This study looks at the genes behind cardiomyopathy (a disease of the heart muscle). It may help explain why it happens in your family and guide better care for you and relatives.
Milan, LombardyAges 18–80 - NCT05556460Recruiting
Device trial for fixing severe tricuspid valve leakage without surgery
This trial tests the DragonFly-T system to improve symptoms and heart function in people with severe tricuspid regurgitation (a leaky heart valve) using a catheter-based repair. It may help reduce valve leak–related symptoms when standard medication isn’t enough and surgery risk is higher.
Chengdu, SichuanAges 18 years+ - NCT05556395Recruiting
Study after stroke to help thinking and memory recovery
This trial looks at stroke patients who can show specific scan findings on an MRI, then uses thinking tests by phone to track cognitive (thinking and memory) changes. It may help researchers understand whether targeting brain blood-flow disruption can improve post-stroke cognition.
Baltimore, MarylandAges 18 years+ - NCT05557526Recruiting
Improving quality of life after atrial fibrillation ablation
This study aims to improve how patients feel in daily life after a procedure to treat atrial fibrillation (an irregular heartbeat). It focuses on whether better patient expectations and support can lead to a better quality of life after the procedure.
Düsseldorf, North Rhine-WestfaliaAges 18 years+ - NCT05556928Recruiting
Cancer and aging study for adults with blood cancers
This study builds a registry to learn how aging and “resilience” relate to outcomes in people with blood cancers. You may be asked to complete questionnaires during UAB visits, which can help researchers better understand needs in older adults.
Birmingham, AlabamaAges 50 years+ - NCT05556902Recruiting
Testing how epidural spinal cord stimulation may help chronic pain
This study looks at how a device that sends mild signals to the area around your spinal cord may work for long-lasting (chronic) pain. You may be asked to visit a research lab, have blood taken, and follow the study plan so researchers can understand the treatment’s effects.
Birmingham, AlabamaAges 18–89 - NCT05558605Recruiting
AI ultrasound guidance for heart risk management
This trial tests whether using an artificial-intelligence (AI) tool during a heart ultrasound can help guide care for people at risk for heart problems. You might benefit if you have symptoms with exercise or heart risk factors, but you do not already have known heart failure or major heart disease.
Alice Springs, Northern TerritoryAges 45 years+ - NCT05559164RecruitingPhase 2
Statins to protect the heart during HER2 breast cancer treatment
This trial tests whether a cholesterol medicine (a statin) can lower the risk of heart damage in people receiving HER2-targeted breast cancer therapy. If you qualify, you may be given a statin and followed with heart tests and blood work to watch for safety and benefit.
Elizabeth, New JerseyAges 18 years+ - NCT05560724Recruiting
Brain stimulation after stroke to track recovery signals
This study looks at whether brain stimulation and brain scans can help measure recovery after an ischemic stroke. It may help researchers understand who benefits from non-invasive brain stimulation by using brain “signal” markers.
Hamburg, Free and Hanseatic City of HamburgAges 18 years+ - NCT05561088Recruiting
Head acupuncture after stroke clot removal
This trial studies whether doing head acupuncture after a procedure to remove a stroke-causing blood clot can improve recovery and safety. You may be considered if you had endovascular clot removal within 24 hours and meet specific brain-scan and stroke-severity measures.
Xi'an, ShaanxiAges 18–100 - NCT05560958Recruiting
Heart procedure study for specific BIOTRONIK EP products
This study collects real-world follow-up information after certain heart procedures that use specific BIOTRONIK equipment. It may help confirm how well these devices work in everyday care and improve future recommendations.
FriedrichshafenAges 18 years+ - NCT05561387RecruitingPhase 3
Drug combinations for newly diagnosed myeloma without transplant
This study compares different combinations of medicines for people newly diagnosed with multiple myeloma who cannot safely get a stem cell transplant. It aims to find which drug plan works best and is tolerable for people with “frail” or “intermediate fit” health.
Anchorage, AlaskaAges Any age - NCT05562167RecruitingPhase 2
Inorganic nitrate plus exercise for heart failure performance
This Phase 2 study tests whether taking inorganic nitrate can improve exercise ability and heart-function symptoms in people with heart failure with reduced pumping. It also checks whether the treatment is safe when combined with an exercise program.
St Louis, MissouriAges 19–79 - NCT05563337Recruiting
Renal denervation for young women with high blood pressure
This study tests a procedure called renal denervation to help lower blood pressure in young women with high blood pressure that’s not too severe. The goal is to see if the treatment can improve blood pressure control safely.
BordeauxAges 18–40 - NCT05563376Recruiting
Clinic visit for people with Fontan heart circulation
This study is for people born with a single-ventricle heart condition who now live with a Fontan circulation. It mainly focuses on having a dedicated clinic visit (“Fontan clinic session”) and checking how that care works for you.
ErlangenAges 6–60 - NCT05564793Recruiting
Noninvasive heart mapping to improve CRT outcomes
This trial tests whether a special noninvasive heart “mapping” test done on the body can help improve outcomes for people who need a CRT device. It studies whether mapping before implantation can better guide or predict how well the CRT will work.
AmsterdamAges 18–85 - NCT05564689Recruiting
Tests coronary blood flow in heart failure patients with CRT
This study measures how well blood flows in the heart (coronary flow) in people with heart failure with reduced pumping strength and a specific heart rhythm problem called left bundle branch block. It focuses on people who already have a cardiac resynchronization therapy (CRT) device and have stable treatment, to see how coronary flow relates to their heart condition.
AalborgAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,989 recruiting cardiology studies from the U.S. registry right now, out of 15,300 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.