Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,626 recruiting studies in this area right now.
By phase
- Not applicable7,647
- Phase 4471
- Phase 2470
- Phase 3439
- Phase 1350
- Phase 1/Phase 2161
- Phase 2/Phase 388
Top conditions
- Stroke798
- Heart Failure538
- Hypertension390
- Cardiovascular Diseases374
- Coronary Artery Disease361
- Multiple Myeloma328
- Atrial Fibrillation258
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke138
- Pulmonary Hypertension105
- Myocardial Infarction96
- Congenital Heart Disease83
- Peripheral Arterial Disease80
- Stroke, Ischemic77
- Aortic Valve Stenosis76
- Acute Coronary Syndrome74
- Obesity74
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital67
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine57
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California449
- Alabama195
- Arizona183
- Massachusetts174
- New York165
- Florida141
- Texas122
- Maryland119
- Minnesota118
- Illinois111
Recruiting studies9,626 total
- NCT07311135Recruiting
Smartwatch Oxygen Accuracy in Pulmonary Hypertension
This study tests how well a smartwatch measures oxygen levels in people with pulmonary hypertension during a 6-minute walk. It could help find a simpler way to check oxygen at home.
GlasgowAges 18 years+ - NCT07312136Enrolling by invitation
Liver health follow-up study for type 2 diabetes
This study follows up on people with type 2 diabetes who already took part in an earlier study about liver health. It uses an MRI scan to check the liver for fat and other changes, helping doctors understand the long-term impact of metabolic dysfunction-associated steatotic liver disease (MASLD).
Linköping, Östergötland CountyAges 18 years+ - NCT06436092Recruiting
Stent treatment for left main coronary artery disease
This trial studies a new way to treat blockages in the left main coronary artery using a drug-coated stent. It aims to find out if a careful approach with a single stent and temporary side-branch support works well for people with heart disease.
Ichinomiya, Aichi-kenAges 18 years+ - NCT06709898Recruiting
Returning to work after a stroke
This study looks at how job accommodations can help people return to work after a stroke. It focuses on those who had a stroke within the last year and have some thinking or emotional symptoms.
Helsinki, UusimaaAges 18–68 - NCT07308639Recruiting
Eye disease health data study in Germany
This study looks at health records in Germany to understand how many people have certain eye conditions like age-related macular degeneration, diabetic macular edema, or retinal vein occlusion. It also tests new ways to use this information for research.
LeverkusenAges 18 years+ - NCT07312188RecruitingPhase 2
F182112 for relapsed or refractory multiple myeloma
This trial tests a new drug, F182112, for people whose multiple myeloma came back or didn't respond to prior treatments that included lenalidomide and a proteasome inhibitor. It may help if your disease has active signs like high protein levels.
TianjinAges 18 years+ - NCT07311330RecruitingPhase 2
Investigation of YN001 for Men with ED and Artery Disease
This study tests an investigational drug (YN001) for men with mild to moderate erectile dysfunction who also have hardening of the arteries (atherosclerosis) in the heart, brain, or legs. The goal is to see if the drug helps improve erections while being safe.
Beijing, JilinAges 18–75 - NCT07306949RecruitingPhase 4
Acoramidis for transthyretin cardiac amyloidosis
This trial tests a new medicine called acoramidis for people with a heart condition caused by a protein called transthyretin. It includes people who are newly diagnosed or who are already taking another drug (tafamidis) and may benefit from switching. The goal is to see how well acoramidis works and how it affects heart-related measures.
Bunkyō CityAges 18–100 - NCT07314047Recruiting
A study of a liquid gel for brain AVM treatment
This trial tests a liquid embolic agent (a gel-like material) injected into the blood vessels of a brain arteriovenous malformation (AVM) to block abnormal blood flow. It’s for people aged 18 to 80 with certain types of AVMs that doctors think can be treated this way.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT07307508Recruiting
Scalp block for headache after aneurysm bleeding
This trial tests if a scalp nerve block can better manage severe headaches after a brain aneurysm rupture. It is for patients who had an aneurysm treated with coiling in the intensive care unit.
DohaAges 18 years+ - NCT07312383Recruiting
Skin blood flow study in leg artery disease
This trial uses a special device to measure tiny blood vessels in the skin of patients with severe leg artery disease. It aims to understand how blood flow changes before and after a common treatment to open blocked leg arteries (angioplasty).
OsloAges 18 years+ - NCT06825104Recruiting
Long-term comparison of two ablation methods for persistent AF
This long-term study follows people who already completed a 12-month study comparing two types of heart ablation for persistent atrial fibrillation. It looks at how well the treatments worked over time.
BronAges 18 years+ - NCT07313865Recruiting
Blood infection study to understand heart valve infections
This study collects blood samples and medical information from patients with certain bloodstream infections to better understand why some develop a heart valve infection. The goal is to find out why some people get this complication and how to predict it.
Clermont-Ferrand, FranceAges 18 years+ - NCT07308704Recruiting
Using AI to spot heart muscle disease on echocardiograms
This study at Mayo Clinic is testing an artificial intelligence (AI) tool that analyzes echocardiograms (ultrasound of the heart) to find early signs of four types of heart muscle disease. If the AI flags a high-risk pattern, doctors can learn whether acting on that alert helps catch the condition sooner.
Rochester, MinnesotaAges 18 years+ - NCT07310693Recruiting
Validating a score to find hidden cancer in blood clot patients
This study tests how well a scoring system (CLOVER) can detect undiagnosed cancer in people who have had a blood clot (deep vein thrombosis or pulmonary embolism). Researchers want to see if the score can predict hidden cancer, which may lead to earlier treatment.
Barcelona, BarcelonaAges 18 years+ - NCT07313410Recruiting
Near-infrared light study for better understanding of PAD
This study uses near-infrared light to learn more about peripheral artery disease (PAD) in adults. It aims to help doctors better understand how PAD affects the body.
Arlington, TexasAges 18 years+ - NCT07312942Recruiting
Breathing and exercise for multiple myeloma patients
This trial tests whether adding slow, controlled breathing exercises to a supervised exercise program can improve your quality of life and physical function while you are on daratumumab treatment for multiple myeloma.
MadridAges 18 years+ - NCT07315347Recruiting
Treating blood clots in the lung at home for cancer patients
This study tests whether people with active cancer and a new blood clot in the lung can be safely treated at home instead of in the hospital. If you have cancer and a blood clot that is not causing severe symptoms, you may be able to join this trial.
Colombes, FranceAges 18 years+ - NCT07312565Recruiting
Checking for belly aneurysms after brain aneurysm
This study checks if people who had a brain aneurysm (subarachnoid hemorrhage) later develop an abdominal aortic aneurysm, which is a bulge in the main artery in the belly. They will use an ultrasound to look at the abdominal aorta about a year or more after the brain bleed.
LeidenAges 18 years+ - NCT07310849Recruiting
Digital health support for older adults with diabetes
This study tests a digital care program using the LINE messaging app to help older adults with diabetes and other chronic conditions manage their health. It may be a good fit if you are 50 or older, have type 2 diabetes plus another condition like high blood pressure, and are comfortable using a smartphone.
New Taipei City, Wugu DistrictAges 50 years+ - NCT07311044Recruiting
Heart health and voice study at Mayo Clinic
This study at Mayo Clinic looks at how heart and lung blood pressure (cardiovascular/pulmonary hypertension) might relate to voice characteristics. Researchers will use voice recordings from people having routine echocardiograms to see if voice changes can help detect heart problems earlier.
Rochester, MinnesotaAges 18 years+ - NCT07313501Recruiting
Comparing PERC and YEARS for diagnosing pulmonary embolism
This study compares two ways of checking for a pulmonary embolism (a blood clot in the lung) in the emergency room. It looks at the PERC score and the YEARS algorithm to see if they can help doctors decide when to do a D-dimer test and chest imaging, potentially reducing unnecessary tests.
StrasbourgAges 18 years+ - NCT07315178Recruiting
Digital twin study for chronic aortic dissection
This study is creating a digital twin model to predict how chronic thoracic aortic dissection progresses. If you have a type A or type B aortic dissection, this study may help researchers better understand your condition without additional stress or invasive procedures.
DijonAges 18 years+ - NCT07315087RecruitingPhase 1
CAR T-cell therapy for autoimmune diseases
This trial tests a special type of cell therapy (CAR T-cells) that targets two markers on immune cells, CD19 and BCMA, to calm overactive immune systems in people with certain autoimmune diseases. It's for those whose disease has not been controlled by standard treatments.
TianjinAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,626 recruiting cardiology studies from the U.S. registry right now, out of 14,734 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.