Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,626 recruiting studies in this area right now.
By phase
- Not applicable7,647
- Phase 4471
- Phase 2470
- Phase 3439
- Phase 1350
- Phase 1/Phase 2161
- Phase 2/Phase 388
Top conditions
- Stroke798
- Heart Failure538
- Hypertension390
- Cardiovascular Diseases374
- Coronary Artery Disease361
- Multiple Myeloma328
- Atrial Fibrillation258
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke138
- Pulmonary Hypertension105
- Myocardial Infarction96
- Congenital Heart Disease83
- Peripheral Arterial Disease80
- Stroke, Ischemic77
- Aortic Valve Stenosis76
- Acute Coronary Syndrome74
- Obesity74
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital67
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine57
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California449
- Alabama195
- Arizona183
- Massachusetts174
- New York165
- Florida141
- Texas122
- Maryland119
- Minnesota118
- Illinois111
Recruiting studies9,626 total
- NCT06178887Recruiting
Cardiac MRI for heart and blood vessel issues in Turner syndrome
This study uses cardiac MRI to look for heart and blood vessel differences in adults with Turner syndrome. It may help find problems early so you can get the right care.
ModenaAges 18 years+ - NCT07302659Recruiting
Comparing two aortic clamping methods in off-pump bypass
This study compares two ways to clamp the aorta during off-pump heart bypass surgery to see which is safer for your brain and body. If you are having bypass surgery without a heart-lung machine, you may be able to join.
BeijingAges 18 years+ - NCT07299162Recruiting
Virtual reality therapy for arm recovery after stroke
This trial tests whether virtual reality therapy can help improve arm and hand function in people who had a stroke within the past 6 weeks to 6 months. You must be able to do some arm movement and have no major health issues that prevent participation.
Istanbul, BahçelievlerAges 18 years+ - NCT07297589RecruitingPhase 3
CT scan of heart fat after heart attack
This study uses a CT scan to look at the layer of fat around the heart in people who recently had a heart attack and have type 2 diabetes and obesity. It aims to understand how this fat relates to inflammation and heart health.
León, GuanajuatoAges 18 years+ - NCT07297342Recruiting
Comparing ways to use the 'Get Ready' app for weight loss surgery
This study compares two ways of using a smartphone app called 'Get Ready' to help people follow their pre-surgery plan before weight loss surgery. It aims to see which approach helps patients stay on track better.
GeelAges Any age - NCT07298044RecruitingPhase 4
Switching from tafamidis to acoramidis for heart amyloidosis
This study will see how switching from tafamidis to a newer medicine called acoramidis changes the level of a protein (called transthyretin) in your blood. The goal is to see if acoramidis might work better for people with this type of amyloidosis that affects the heart.
Sankt Pölten, Lower AustriaAges 18–90 - NCT07298473Recruiting
Redo ablation for recurrent atrial fibrillation with Sphere-9 catheter
This trial tests a new catheter and system for people who have had one previous ablation for atrial fibrillation but still have symptoms. It aims to see if a repeat procedure can safely and effectively treat recurrent episodes.
Birmingham, AlabamaAges 18 years+ - NCT07303777RecruitingPhase 2
Study of ABP-745 for people with atherosclerosis
This trial tests a new medication called ABP-745 to see if it helps people with atherosclerosis (hardening of the arteries). It is for people who are already taking a cholesterol-lowering medicine and who have had a special heart artery X-ray (coronary angiography).
Beverly Hills, CaliforniaAges 18–75 - NCT07306182RecruitingPhase 2
Testing SGC001 for anterior wall heart attack
This study tests an investigational drug called SGC001 for people having a heart attack affecting the front wall of the heart. The goal is to see if adding this drug to the standard artery-opening procedure helps improve outcomes.
Shanghai, Shanghai MunicipalityAges 18–79 - NCT07297329RecruitingPhase 3
Newly diagnosed multiple myeloma trial for transplant-ineligible patients
This trial tests a new drug called SCTC21C combined with standard treatments (bortezomib, lenalidomide, and dexamethasone) for people newly diagnosed with multiple myeloma who cannot have a stem cell transplant. The goal is to see if this combination is safe and works better than current options.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07298447RecruitingPhase 3
Donidalorsen for children with hereditary angioedema
This study tests a new medicine, donidalorsen, to prevent swelling attacks in children ages 2 to 11 with hereditary angioedema (HAE). If your child has HAE type 1 or 2, this trial may help find a treatment option.
Santa Monica, CaliforniaAges 2–11 - NCT07300163Recruiting
FeetSee: Thermal images for diabetes foot health
This study collects thermal (heat) images of the feet of people with diabetes who have had a healed foot ulcer. The goal is to see if these images can help prevent future foot problems.
VilniusAges 18 years+ - NCT07301034RecruitingPhase 3
Ziltivekimab for plaque after a heart attack
This study tests a drug called ziltivekimab to see if it can reduce fatty plaque buildup in heart arteries after a heart attack. It's for people who had a heart attack treated with a stent and have mild blockages in other arteries.
ViennaAges 18 years+ - NCT06826963Recruiting
Eccentric exercise for older adults with heart failure and muscle loss
This study tests whether a special type of exercise (eccentric, or lengthening, exercises) can help older adults with heart failure who also have muscle loss. It aims to see if the exercise is safe and improves strength and function.
Verona, VeronaAges 65–85 - NCT07301307Recruiting
Blood pressure and fluid management during surgery
This trial tests a new tool that helps doctors manage fluids and blood pressure during surgery. It uses a special index (HPI) and computer-assisted fluid management to keep your blood pressure stable, which may reduce complications.
Athens, AtticaAges 18 years+ - NCT07302854RecruitingPhase 2/Phase 3
Clot-busting medicine for medium vessel strokes
This trial tests a new clot-busting medicine called tenecteplase, given directly into the blood vessel in the brain, to treat strokes caused by a blockage in a medium-sized artery. The goal is to see if it can help restore blood flow and reduce disability, especially for patients who can be treated within 24 hours of stroke onset.
Wuhan, HubeiAges 18 years+ - NCT07304115Recruiting
Noise from mechanical heart valve and quality of life
This study looks at how the noise from a mechanical heart valve affects your quality of life after surgery. You will be asked about your memories of the information you received before surgery and how you feel now.
ParisAges 18 years+ - NCT07298694Enrolling by invitation
Choosing a hypertension medication with helpful defaults
This trial tests whether changing the default options in doctors' ordering systems can help patients get the best medication for high blood pressure. You may be eligible if you are an adult who recently received a prescription for a common blood pressure drug at a participating clinic.
Danville, PennsylvaniaAges 18 years+ - NCT07305116RecruitingPhase 1
CAR T-cell therapy for autoimmune diseases
This trial tests a new immune therapy called CAR T-cells that target two proteins (CD19 and BCMA) to treat autoimmune diseases like lupus, nephrotic syndrome, and others. It is for people whose standard treatments have not worked well enough.
Hangzhou, ZhejiangAges 3 years+ - NCT07304817RecruitingPhase 2
Comparing two heart and kidney medicines in heart failure
This study tests if a new medicine (vicadrostat) works differently than an older one (spironolactone) in people with heart failure or heart disease and reduced kidney function. It aims to understand how they affect proteins in the blood and kidney blood flow.
Groningen, Provincie GroningenAges 18 years+ - NCT07302009Recruiting
Cooling treatment for brain hemorrhage patients
This trial tests a bladder-based cooling device to see if it can safely control fever in patients with a new brain hemorrhage. It may help prevent further brain injury and improve recovery.
Nanchang, JiangxiAges 18–85 - NCT07303439Recruiting
Comparing heart artery treatments in people with diabetes
This study compares using a special medicated balloon plus a medicated stent versus using just one of them to open blocked heart arteries in people with diabetes. It aims to find which treatment works better to keep arteries open longer.
Dublin, County DublinAges 18 years+ - NCT07303855Recruiting
Better fluid management after major abdominal surgery
This study compares two ways of giving fluids to people after major abdominal surgery in the ICU. It will see if using a measure of how much blood the heart pumps (cardiac index) is better than the usual method based on vein pressure.
Jakarta Pusat, DKI JakartaAges 18–65 - NCT07302971Recruiting
Telemedicine for stroke care in Chinese hospitals
This study tests if connecting smaller hospitals with stroke experts through telemedicine improves treatment for people having an acute ischemic stroke. It may help you get faster, better care if you live in a less populated area.
Beijing, Beijing MunicipalityAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,626 recruiting cardiology studies from the U.S. registry right now, out of 14,734 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Injuries & trauma
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.