Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,626 recruiting studies in this area right now.
By phase
- Not applicable7,647
- Phase 4471
- Phase 2470
- Phase 3439
- Phase 1350
- Phase 1/Phase 2161
- Phase 2/Phase 388
Top conditions
- Stroke798
- Heart Failure538
- Hypertension390
- Cardiovascular Diseases374
- Coronary Artery Disease361
- Multiple Myeloma328
- Atrial Fibrillation258
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke138
- Pulmonary Hypertension105
- Myocardial Infarction96
- Congenital Heart Disease83
- Peripheral Arterial Disease80
- Stroke, Ischemic77
- Aortic Valve Stenosis76
- Acute Coronary Syndrome74
- Obesity74
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital67
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine57
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California449
- Alabama195
- Arizona183
- Massachusetts174
- New York165
- Florida141
- Texas122
- Maryland119
- Minnesota118
- Illinois111
Recruiting studies9,626 total
- NCT06877520Recruiting
Study of a new device for fixing leaky tricuspid valve
This trial tests a new, less-invasive device called 'Pivot Extend' for people with a severe leaky tricuspid valve (tricuspid regurgitation) who still have symptoms despite taking medicines. The goal is to see if the device can safely help reduce the leak and improve symptoms.
Tbilisi, K'alak'i T'bilisiAges 18 years+ - NCT06010511Recruiting
White matter changes and brain fluid study in older adults
This study uses special MRI scans to look at white matter changes in the brain (often linked to memory problems). It may help doctors understand more about these changes in older adults visiting memory or geriatric clinics.
LeidenAges 65 years+ - NCT06754709Recruiting
Protein Changes in Children Having Heart Surgery
This study looks at a specific protein change in blood and heart tissue of children having heart surgery with a heart-lung machine. The goal is to understand how this protein might affect recovery.
NantesAges Up to 17 years - NCT07210606RecruitingPhase 4
Sleep apnea treatment study for veterans with heart failure
This study looks at how well a medicine called trazodone might help treat central sleep apnea in veterans who also have heart failure. It aims to improve sleep and breathing, which may help you feel better.
Detroit, MichiganAges 18 years+ - NCT06913127Recruiting
High-intensity exercise for better recovery after stroke
This trial studies whether doing high-intensity exercise helps people recover walking and other skills better than usual therapy after a stroke. It is for people who are already in a rehabilitation hospital and can walk a short distance with help.
SingaporeAges 21–99 - NCT07203222Recruiting
Laser vs electric stimulation for shoulder pain after stroke
This study compares two non-invasive treatments—low-level laser therapy and electrical nerve stimulation—to see which works better for relieving moderate to severe shoulder pain in people who have had a stroke. If you have had a stroke in the last 2 weeks to 6 months and have shoulder pain, this trial may be an option for you.
Ankara, YenimahalleAges 18–75 - NCT07210723RecruitingPhase 2/Phase 3
Study of danicamtiv for genetic and familial dilated cardiomyopathy
This trial tests if danicamtiv can improve heart function in people with dilated cardiomyopathy caused by certain genetic changes. It may help those who have stable symptoms but still need more treatment options.
Birmingham, AlabamaAges 18 years+ - NCT07203404RecruitingEarly Phase 1
A study of a universal CAR-T cell therapy for autoimmune diseases
This trial tests a new treatment called RD06-05, which uses specially engineered immune cells to target and potentially reset parts of the immune system that are attacking your own body. It is being studied for several autoimmune conditions like lupus, vasculitis, kidney diseases, and more.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07205341Recruiting
Artery blood flow monitoring during heart valve procedure
This study is testing a new way to monitor blood flow and heart function during a valve replacement procedure. It may help doctors track how well the heart is pumping.
Boulder, ColoradoAges 18–80 - NCT07205328RecruitingPhase 2
Testing MT200605 for acute ischemic stroke
This trial tests whether MT200605 can help people who recently had an ischemic stroke (a type of stroke caused by a blocked blood vessel). The drug is given within 24 hours of symptoms starting, and you may join even if you received clot-busting treatment already.
Beijing, Beijing MunicipalityAges 18–80 - NCT07209475RecruitingPhase 4
Amnio-Maxx for healing diabetic foot ulcers
This trial tests whether a special wound dressing called Amnio-Maxx can help heal foot ulcers in people with diabetes. You may qualify if you have a diabetic foot ulcer that hasn't healed much with standard care.
Burbank, CaliforniaAges 18 years+ - NCT07210047RecruitingPhase 1/Phase 2
Study of HuL001 for multiple myeloma that has come back or not responded
This trial tests a new drug called HuL001 combined with lenalidomide and dexamethasone for people with multiple myeloma that has returned or stopped responding to at least three prior treatments. It aims to see if this combination can help when other options have failed.
TaipeiAges 18 years+ - NCT07209358Recruiting
Study of a new treatment for diabetic foot ulcers
This trial tests a new product (EDX110) to help heal diabetic foot ulcers that haven't improved with standard care. It's for people with diabetes who have a non-infected or mildly infected ulcer on their foot.
Phoenix, ArizonaAges 18–90 - NCT07209852Recruiting
Pacing the heart's left bundle branch area with a new lead
This trial tests a new pacing lead placed in the left bundle branch area of the heart. It is for people who need a pacemaker for certain slow or irregular heart rhythms.
BrugesAges 18 years+ - NCT07209098Recruiting
Heart failure study testing CCM therapy
This study tests a therapy called Cardiac Contractility Modulation (CCM) for people with heart failure. It uses a device to help the heart pump more strongly, and researchers compare it to standard care using patient records.
Marlton, New JerseyAges 18 years+ - NCT07209527Enrolling by invitationEarly Phase 1
Truway diagnostic tools in primary care
This trial tests new diagnostic tools that doctors can use in primary care. Researchers want to see if these tools help find the right diagnosis faster and more accurately.
New York, New YorkAges Any age - NCT07204938Enrolling by invitationPhase 3
Long-term study of navenibart for hereditary angioedema
This study tests navenibart over a longer period to see if it continues to prevent swelling attacks in people with hereditary angioedema. It is for people who were already in a previous navenibart study.
Scottsdale, ArizonaAges 12 years+ - NCT07211243Recruiting
Comparing two dressings for infected leg ulcers
This trial tests if a new version of a special dressing (Suprasorb X+PHMB Pro) works better than the current version for treating infected venous leg ulcers. It may help people with mildly to moderately draining wounds that are infected.
BialystokAges 18 years+ - NCT06925178Recruiting
Imaging database study for recent stroke patients
This study is building a standard imaging database for people who have recently had a stroke. By participating, you will help doctors better understand how to use different types of scans to diagnose and treat cerebrovascular disease.
Beijing, Beijing MunicipalityAges 18–80 - NCT00932139Recruiting
Electro-acupuncture to help lower high blood pressure
This trial studies whether electro-acupuncture can improve blood pressure in people with mild coronary artery disease or high blood pressure. If it works, it may offer a non-medicine approach to better blood pressure control.
Irvine, CaliforniaAges 18–85 - NCT06084052Recruiting
Mobile app study to prevent foot ulcers in diabetes
This trial tests a mobile app to help prevent foot ulcers in people with diabetes who are at high risk. You will use the app to track your foot health and get advice to keep your feet safe.
LondonAges 18–100 - NCT06922409Recruiting
Light therapy for stroke recovery in rehabilitation
This trial tests whether exposure to naturalistic light can help reduce fatigue and depression after a stroke. It is designed for patients in a rehabilitation unit who are able to communicate and cooperate with simple physical exams.
Glostrup Municipality, Capital RegionAges 18 years+ - NCT06927791Recruiting
Using AI to spot heart problems earlier
This trial uses machine learning (a type of artificial intelligence) to help doctors diagnose acute heart or vessel conditions faster. It may lead to quicker treatment for patients with sudden heart problems.
BaselAges 18 years+ - NCT06140966RecruitingPhase 2
Daratumumab and Carfilzomib combo for high-risk multiple myeloma
This trial tests a combination of the drugs daratumumab, carfilzomib, lenalidomide, and dexamethasone given before and after a stem cell transplant for people with ultra high-risk multiple myeloma. The goal is to see if this regimen is safe and more effective than standard treatments.
Wuhan, HubeiAges 18–70
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,626 recruiting cardiology studies from the U.S. registry right now, out of 14,734 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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- Injuries & trauma
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.