Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,989 recruiting studies in this area right now.
By phase
- Not applicable7,969
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke845
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,986 total
- NCT05959746Recruiting
AI video tool study for early stroke and TIA diagnosis
This study collects short video and clinical information from people being checked for stroke or a “mini-stroke” (TIA) soon after symptoms start, to help build an AI diagnostic tool. You may be contacted again for a follow-up visit within about 4 months.
Nîmes, GardAges 18 years+ - NCT05960604Recruiting
Monitoring blood pressure during surgery to predict low blood pressure
This study tests special ways of analyzing blood-pressure recordings during major surgery to better understand why some people develop low blood pressure (hypotension). If you have high blood pressure and need invasive blood-pressure monitoring, your surgery team will use readings to study patterns that may help predict or prevent low blood pressure.
AnkaraAges 18 years+ - NCT05960890Recruiting
Study of chronic heart failure after hospital discharge
This study follows adults with chronic or newly diagnosed heart failure to learn how patients do after they leave the hospital, mainly while taking heart medicines by mouth. It may help researchers better understand which patients have different outcomes and needs.
Taizhou, JiangsuAges 18 years+ - NCT05960721Recruiting
Low-dose blood thinner versus standard care after heart appendage closure
This study looks at whether a lower-dose blood thinner works as well as the usual recommended anti-clot treatment after a procedure that closes off the heart’s left atrial appendage. It may help reduce bleeding risk while still preventing dangerous blood clots.
Xi'an, ShannxiAges 18 years+ - NCT05960968Recruiting
Hospital heart failure registry for adults in Santiago
This is a registry study that collects information from adults hospitalized for heart failure in Santiago. It aims to better understand heart failure in real-world patients, including differences by sex, by tracking what happens during the hospital stay.
Santiago, Santiago MetropolitanAges 18 years+ - NCT05961202RecruitingPhase 2/Phase 3
Hydroxychloroquine for inflammatory heart muscle weakness
This trial tests hydroxychloroquine to see if it improves symptoms and heart function in people with inflammatory cardiomyopathy (inflammation of the heart muscle). It’s mainly for adults with a specific type of past myocarditis and ongoing heart failure despite standard treatments.
Wuhan, HubeiAges 18–80 - NCT05961488Recruiting
Coronary CT scan after cardiac arrest to check heart artery blockage
This trial tests whether a special CT scan (coronary CT angiography) can help rule out coronary artery disease—the common artery blockage causing heart problems—after someone has survived an out-of-hospital cardiac arrest. It may help doctors quickly decide who needs or does not need further heart procedures.
ReimsAges 18 years+ - NCT05961748Recruiting
Brain and heart illness registry for adults in China
This study is a registry that collects health information from adults who have certain new heart and/or brain conditions. It may help researchers understand how these problems occur together and improve future care planning.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05961865Recruiting
Study of inflammation during catheter ablation for atrial fibrillation
This study measures changes in inflammation in people with atrial fibrillation (AF) who are getting a catheter ablation procedure. It may help doctors better understand what happens in the body during the procedure and why some patients do better than others.
MilanAges 18–85 - NCT05962164Recruiting
Passive heat therapy for COPD in non-smokers
This study tests whether using passive heat (warming therapy, not exercise) can improve breathing and body comfort in people with COPD who are not currently flaring up. It may help by seeing if heat changes how well you tolerate breathing and physical activity during testing.
Kelowna, British ColumbiaAges 40 years+ - NCT05962372Recruiting
Culturally tailored diet program for adults in Puerto Rico
This study tests a diet program designed to fit Puerto Rico culture and daily life. It may help adults with weight or blood sugar or blood fat concerns improve their health through regular check-ins.
San JuanAges 30–65 - NCT05963126Recruiting
Fetuin A test to predict kidney function decline
This study looks at a blood protein called fetuin A to see if it can forecast worsening kidney function over time in people with treated high blood pressure. It may help identify who is at higher risk for kidney decline so care can be adjusted earlier.
Ostrava, Czech RepublicAges 18–100 - NCT05962840RecruitingPhase 4
Rituximab plus telitacicept for ANCA vasculitis
This Phase 4 trial studies whether rituximab combined with telitacicept works better and is safe for people with severe active ANCA-associated vasculitis (including certain subtypes like GPA or MPA). If you meet specific blood test and disease activity criteria, you may be considered to help lower inflammation and prevent flare-ups.
BeijingAges 18–65 - NCT05963698Recruiting
Closing off a heart pouch to prevent stroke
This study tests a procedure that seals off the left atrial appendage (a small heart pouch) to help prevent stroke in people with atrial fibrillation. You may be considered if your stroke risk is high and you are already on blood-thinner medicine.
Birmingham, AlabamaAges 18 years+ - NCT05964660Recruiting
Ultrasound-guided imaging for heart rhythm ablation planning
This trial tests a way to use heart ultrasound images together with other heart scans to better plan catheter ablation for dangerous heart rhythm problems. It may help doctors identify the right target areas in the heart before you have the procedure.
Lübeck, Schleswig-HolsteinAges 18–100 - NCT05965115Recruiting
Screening study for family members of multiple myeloma patients
This trial screens first-degree relatives of people with multiple myeloma to check for early signs of the disease before symptoms. It may help doctors understand risk in families and find problems sooner if they occur.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT05965362Recruiting
Study biomarkers to predict outcomes in heart infection
This study looks at blood and other lab test results (“biomarkers”) to better predict what may happen to people with infective endocarditis, a serious infection of the heart lining or heart valves. Your information may help doctors estimate risk and choose care more safely and effectively.
Xi'an, ShaanxiAges 18 years+ - NCT05965284RecruitingPhase 4
Telitacicept to help keep ANCA vasculitis in remission
This trial studies telitacicept to see if it can help keep ANCA-associated vasculitis in remission after initial treatment with steroids and rituximab. It may help prevent future flare-ups, while closely watching for side effects.
Beijing, Beijing MunicipalityAges 18–65 - NCT05965453Recruiting
Castor stent graft study for sudden type B aortic tears
This study looks at outcomes for people who had emergency (acute) type B aortic problems treated with a specific stent graft called the Castor single-branch device. It helps doctors understand how well this device works for selected patients and what factors affect results.
Xi'an, ShaanxiAges 18–95 - NCT05966675Recruiting
Special heart pacing after TAVI to help protect heart function
This trial looks at a physiologic (more natural) heart pacing approach to prevent weakening of the heart’s main pumping chamber after TAVI. It enrolls people who recently had TAVI and now meet standard reasons for needing a permanent pacemaker.
KatowiceAges 18 years+ - NCT05967663Recruiting
Staged vs same-day heart artery repair after a heart attack
This study compares doing all heart artery procedures right away versus doing part of them later in people who had a heart attack and have blockage in more than one artery. It aims to see which approach is safer and works better after the initial emergency procedure.
ShanghaiAges 18 years+ - NCT05967741Recruiting
Dietary erythritol trial for blood clot and inflammation health
This study tests whether eating erythritol (a sugar substitute) affects how your platelets (blood-clot cells) react and how inflamed your blood vessels are. You may benefit by helping researchers understand whether erythritol has effects on heart-and-blood-vessel risk.
Davis, CaliforniaAges 18–70 - NCT05968053Recruiting
Testing microplastics detection in neurosurgery patients
This study checks whether microplastics and nanoplastics can be detected in people undergoing neurosurgery. If it works, it could help doctors better understand possible material exposures around brain and nerve procedures.
Beijing, Beijing MunicipalityAges 18–80 - NCT05968417Recruiting
Study of new lab tests using blood or bone marrow samples for myeloma
This trial studies myeloma (and closely related blood disorders) by using extra blood or bone marrow samples for lab research. It aims to help discover new ways to understand or treat myeloma.
SuttonAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,989 recruiting cardiology studies from the U.S. registry right now, out of 15,300 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.