Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,989 recruiting studies in this area right now.
By phase
- Not applicable7,969
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke845
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,986 total
- NCT06025149Recruiting
Study of a New Biological Heart Valve 'UniLine'
This study tests a new biological heart valve called 'UniLine' for people who need to replace their mitral valve (the valve between the left heart chambers) or aortic valve (the main valve sending blood to the body) for the first time. If you qualify, you would have planned surgery (not an emergency) and need to be free of certain other serious health conditions.
Kemerovo, Kemerovo OblastAges 18–80 - NCT06025630RecruitingPhase 1/Phase 2
Testing TUDCA for blood pressure control
This study tests whether a supplement called TUDCA can help lower blood pressure by reducing stress inside cells. It's looking for people with high-normal blood pressure who are not on many heart medications.
Fort Worth, TexasAges 18–80 - NCT06026345Recruiting
Affera heart procedure registry study
This registry collects information about people who have a heart procedure using the Affera platform. It helps doctors learn more about how well the procedure works in the real world.
BrusselsAges 18 years+ - NCT06027294Recruiting
Blood flow and muscle function study for stroke survivors
This study looks at how blood flow affects muscle function after a stroke. It may help researchers understand recovery better and find new ways to improve movement.
Milwaukee, WisconsinAges 18–85 - NCT06027788Recruiting
Embolic protection during heart valve surgery
This trial tests a device that may help protect your brain from small particles during heart valve surgery. It is for people 60 and older having certain types of valve replacement or repair.
North Little Rock, ArkansasAges 60 years+ - NCT06028087Recruiting
Blood Clot Prevention Study in Myeloma Patients
This study looks at how blood thinners are used in people with newly diagnosed multiple myeloma. The goal is to find better ways to prevent blood clots during treatment.
RomaAges 18 years+ - NCT06028165Recruiting
Heart bypass surgery planning with CT versus standard angiogram
This trial compares two ways to plan heart bypass surgery: a CT scan that measures blood flow (CT-FFR) versus the usual heart catheter X-ray (angiogram). It aims to see which method leads to better outcomes for people with blocked heart arteries.
Goyang-si, Gyeonggi-doAges 40–80 - NCT06029491Recruiting
Studying a new suction device for stroke treatment
This trial tests a new device that removes blood clots in the brain using suction. It is for people having a large-vessel ischemic stroke who can be treated within 8 hours of symptoms starting.
Torrance, CaliforniaAges 18–80 - NCT06029348Recruiting
Brain health and resilience in middle age
This study looks at how well the brain's blood vessels work in midlife. It involves two visits to the University of Pittsburgh and includes an MRI and a mental math test.
Pittsburgh, PennsylvaniaAges 40–59 - NCT06029400Recruiting
Heart CT scan to study heart muscle
This study uses a special CT scan to take detailed images of your heart muscle. The goal is to see how well this scan can identify heart problems like inflammation or scarring.
MilanAges 18–100 - NCT06030843RecruitingPhase 2/Phase 3
Testing empagliflozin for heart and kidney health
This trial tests if the drug empagliflozin can improve kidney function in people hospitalized with heart failure who also develop acute kidney injury. It may help protect the kidneys while treating the heart condition.
Bangkok, PathumwanAges 18 years+ - NCT06031610Recruiting
Carotid artery opening study for brain health
This study tests if opening a narrowed carotid artery can reduce brain damage from small vessel disease. It may help patients with carotid artery narrowing prevent cognitive decline.
Hangzhou, ZhejiangAges 40–80 - NCT06031623Recruiting
Using REBOA for non-traumatic cardiac arrest outside hospital
This study tests if a temporary balloon placed in the aorta, called REBOA, can improve blood flow to the heart and brain during CPR for people whose hearts stop due to a non-traumatic cause. It is for adults who have a witnessed cardiac arrest and arrive at the hospital during daytime hours.
Seongnam-si, Gyeonggi-doAges 20–80 - NCT06031714Recruiting
Fetal cells in women with skin ulcers
This study looks at fetal cells that stay in a woman's body after pregnancy to see if they play a role in chronic skin ulcers. It includes women who have had a baby and have a venous, diabetic, sickle cell, or mixed ulcer, as well as healthy women for comparison.
Paris, Île-de-France RegionAges Any age - NCT06032065RecruitingPhase 3
Exercise for peripheral artery disease
This trial tests whether a home-based exercise program is as effective as supervised exercise for improving walking ability in people with peripheral artery disease (PAD). You will be randomly assigned to one of two exercise groups, and you may be asked to drink beetroot juice as part of the study.
Chicago, IllinoisAges 50 years+ - NCT06032533Recruiting
Remote ischemic conditioning for aneurysm brain bleeding
This study tests whether using a blood pressure cuff on the arm to temporarily restrict blood flow (remote ischemic conditioning) can help people recover after a brain bleed from a ruptured aneurysm. It may reduce damage and improve outcomes.
Aarhus N, DanmarkAges 18 years+ - NCT06033014Recruiting
New decision support tool for heart disease patients
This trial tests a new decision support tool for people with ischemic heart disease (reduced blood flow to the heart). It aims to help doctors and patients make better treatment decisions. You may be able to join if you are hospitalized for various forms of heart disease and have significant blockages found during a heart catheterization.
Copenhagen ØAges 18 years+ - NCT06032780Recruiting
Exercise training for chronic heart failure
This study tests if a specific type of leg-strengthening exercise (eccentric resistance training) can help people with stable chronic heart failure feel better and move more easily. If you have heart failure and are not in an acute or very severe stage, this might be an option to improve your daily life.
Rawalpindi, Punjab ProvinceAges 18 years+ - NCT06033378Recruiting
Blood pressure treatment for ICU patients with brain bleed
This trial tests a blood pressure management strategy for patients in the ICU after a bleeding stroke caused by a brain aneurysm. It aims to see if carefully controlling blood pressure can help prevent a dangerous tightening of blood vessels in the brain.
UmeåAges 18 years+ - NCT06033924Recruiting
Home Walking Program for Vets with Leg Artery Disease
This study tests a home-based walking program delivered through telehealth for Veterans with peripheral artery disease (PAD). It aims to help you walk farther with less pain.
Birmingham, AlabamaAges 21 years+ - NCT06033274Recruiting
Global registry for tricuspid valve replacement
This study is a registry that collects data on patients who receive a new type of heart valve replacement for the tricuspid valve through a less invasive catheter procedure. Joining helps doctors learn more about how well this treatment works in real-world patients.
Phoenix, ArizonaAges 18 years+ - NCT06034405Recruiting
Checking spine tissue for heart amyloidosis signs
This trial is looking at leftover tissue from past spine surgeries to see if it contains signs of a heart condition called TTR amyloidosis. It may help find people who have this condition early.
Beverly Hills, CaliforniaAges 50 years+ - NCT06034509Recruiting
Thinking and blood vessel health after head injury
This study looks at how a past traumatic brain injury (TBI) might affect your thinking skills and blood vessel health over time. You may be eligible if you had a TBI at least 3 years ago and have already completed an earlier evaluation at the National Intrepid Center of Excellence (NICoE).
Bethesda, MarylandAges 18–74 - NCT06037096Recruiting
Structured follow-up after pulmonary embolism
This study tests a structured follow-up program for people who have had a pulmonary embolism. The program aims to help you recover better after your clot and lower the chance of future problems.
AalborgAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,989 recruiting cardiology studies from the U.S. registry right now, out of 15,300 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Bones, joints & muscles
- Pain
- Injuries & trauma
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.