Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,626 recruiting studies in this area right now.
By phase
- Not applicable7,647
- Phase 4471
- Phase 2470
- Phase 3439
- Phase 1350
- Phase 1/Phase 2161
- Phase 2/Phase 388
Top conditions
- Stroke798
- Heart Failure538
- Hypertension390
- Cardiovascular Diseases374
- Coronary Artery Disease361
- Multiple Myeloma328
- Atrial Fibrillation258
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke138
- Pulmonary Hypertension105
- Myocardial Infarction96
- Congenital Heart Disease83
- Peripheral Arterial Disease80
- Stroke, Ischemic77
- Aortic Valve Stenosis76
- Acute Coronary Syndrome74
- Obesity74
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital67
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine57
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California449
- Alabama195
- Arizona183
- Massachusetts174
- New York165
- Florida141
- Texas122
- Maryland119
- Minnesota118
- Illinois111
Recruiting studies9,626 total
- NCT06260488Recruiting
Using AI to study leg arteries before amputation
This trial uses artificial intelligence to analyze CT scans and microscope images of the main leg artery. It aims to improve understanding of artery structure. Participation is only for patients who are already scheduled for a leg amputation as part of their medical care.
Strasbourg, Bas-RhinAges 18 years+ - NCT06286878RecruitingPhase 2/Phase 3
Dapagliflozin after a heart attack: recovery study
This trial tests whether a diabetes drug called dapagliflozin (also used for heart failure) can help people recover better after a recent heart attack. It's for adults who are already on standard blood thinners and have had a heart attack in the past week.
São Paulo, São PauloAges 18 years+ - NCT07188233Recruiting
Catheter repair for leaky mitral valve in heart failure
This trial tests a new device (CathHELIX) placed through a vein to repair a leaky mitral valve in people with heart failure. It is for people with moderate to severe mitral regurgitation who still have symptoms despite medical therapy.
Tbilisi, GeorgiaAges 18 years+ - NCT07187440Recruiting
Study of Fabry disease treatment in Chinese children and adults
This study tests an enzyme replacement therapy (agalsidase alfa) for Fabry disease in Chinese children and adults. It's an observational study that follows patients who receive the treatment as part of their regular care.
Hefei, AnhuiAges 7 years+ - NCT07191899RecruitingPhase 1
KN060 for treating high blood pressure
This trial tests a new medication called KN060 for people with high blood pressure (essential hypertension). It is for those who are not on medication or are on a stable single medication, and whose blood pressure is moderately high but not extremely high.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT07192211RecruitingPhase 2
Study of ADR-002K for Heart Failure Patients Having Bypass Surgery
This study tests an experimental drug (ADR-002K) for people with heart failure caused by blocked arteries who are about to have bypass surgery. The goal is to see if it helps the heart recover better after surgery.
Osaka, SuitaAges 18–80 - NCT06670768Recruiting
Comparing two heart imaging tests for blocked arteries
This trial compares two heart imaging tests (SPECT and coronary CTA) to see if a newer method gives a clearer picture of blood flow. If you have been referred for one of these tests, you may be able to help by also having the other test done at no extra risk.
Budapest, BudapestAges 18 years+ - NCT07187570RecruitingPhase 3
Dapagliflozin to prevent atrial fibrillation recurrence after cardioversion
This trial tests if the diabetes drug dapagliflozin can lower the chance of atrial fibrillation (an irregular heartbeat) coming back after a procedure called electrical cardioversion, which uses a shock to restore a normal heart rhythm. If you have AF and are scheduled for cardioversion, you may be able to join.
LinköpingAges 55 years+ - NCT06787482RecruitingPhase 1/Phase 2
Peptide therapy for retinitis pigmentosa
This trial tests a new peptide therapy for people with retinitis pigmentosa (RP), a genetic eye disease that causes vision loss. The goal is to see if the treatment is safe and can help slow or improve vision loss.
CairoAges Any age - NCT06945185Recruiting
Motor imagery training for arm strength after stroke
This trial tests if imagining arm movements (motor imagery training) can help improve arm strength in people who had a stroke at least 6 months ago. It is a non-drug, mental practice approach that may help your brain relearn movement.
IslamabadAges 45 years+ - NCT06945211Recruiting
Mirror therapy for arm movement after stroke
This study tests whether doing arm exercises while watching the reflection of your good arm in a mirror can help improve movement and function in your affected arm after a stroke.
IslamabadAges 45 years+ - NCT06386718Recruiting
Ultrasound of hand arteries in children
This study uses ultrasound to look at the blood vessels in the hands of children before they have surgery. It helps doctors understand hand blood flow better, which can make procedures safer.
AnkaraAges Up to 10 years - NCT07192965Recruiting
Heart scan without ECG for chest pain with high troponin
This trial tests if a coronary CT scan (without needing an ECG) can safely guide care for people who come to the emergency room with chest pain and a high troponin level. It aims to see if this approach works as well as standard tests.
JetteAges 30 years+ - NCT07184814Recruiting
Takayasu's arteritis with lung artery involvement study
This study looks at people with Takayasu's arteritis that also affects the lungs' blood vessels. Researchers want to understand the disease's behavior and outcomes over time.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07185022Recruiting
Clot-busting drug through artery for medium-vessel stroke
This trial tests a clot-busting drug given directly into the arteries of the brain for people who have had a stroke due to a blockage in a medium-sized artery. It aims to see if this treatment can help improve recovery when started up to 72 hours after symptoms begin.
Fuyang, AnhuiAges 18 years+ - NCT07192783Recruiting
Lavender inhalation for anxiety, sleep, and blood pressure
This study tests whether inhaling lavender aroma can help lower anxiety, improve sleep, and reduce blood pressure in people with high blood pressure. It is a simple, non-drug approach that you can try at home.
Ardahan, ArdahanAges Any age - NCT07192341Recruiting
Heart failure drug for people with artificial heart valves
This trial tests a drug called sacubitril/valsartan to see if it helps people who have both a prosthetic heart valve and heart failure with a weak heart pump. The goal is to improve heart function and symptoms.
Kafr ash Shaykh, KafrelsheikhAges 18 years+ - NCT07192029Recruiting
Balloon catheter for stroke clot removal in the carotid artery
This trial tests whether using a special balloon-guided catheter during clot removal (mechanical thrombectomy) improves outcomes for people with a severe stroke caused by a blockage in the internal carotid artery. The study aims to see if this tool helps remove the clot more safely and effectively.
Fuzhou, FujianAges 18 years+ - NCT07190079Recruiting
New way to diagnose blood clots in the lungs using saline
This study tests a new method using a saline solution and a special imaging belt to quickly diagnose pulmonary embolism (a blood clot in the lungs) in people with acute breathing problems. If successful, it could provide a faster, safer alternative to standard CT scans.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07190690Recruiting
Comparing two drug-coated stents for heart attack patients
This trial compares two types of drug-coated stents (one with sirolimus, one with everolimus) in people who have had a heart attack or unstable angina and need a stent. It aims to see which stent works better for new blockages in the heart arteries.
AlicanteAges 18 years+ - NCT07189637Recruiting
Mediterranean diet and intermittent fasting for high blood pressure
This study tests if combining the Mediterranean diet with intermittent fasting can help lower blood pressure in people recently diagnosed with hypertension. It may be a good option if you are looking for a diet-based approach to manage your blood pressure.
IstanbulAges 40–65 - NCT07184892Recruiting
Swallowing therapy after stroke
This study tests if watching swallowing movements (action observation therapy) helps people recover swallowing function after a first-time stroke. It uses a brain imaging technique called fNIRS to see how the brain responds.
Jinan, ShandongAges 18–80 - NCT07188285Enrolling by invitation
Immune system study for active autoimmune diseases
This study uses a blood test called mass spectrometry to look at the immune system in people with active autoimmune diseases. It aims to find patterns that could help doctors better understand and treat these conditions.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07188090RecruitingPhase 2
Mozobil for stem cell transplant study
This study tests if adding Mozobil (a drug that helps release stem cells) before stem cell transplant can improve outcomes for people with multiple myeloma, Hodgkin's lymphoma, or non-Hodgkin lymphoma. If you are eligible, you will receive Mozobil along with standard stem cell mobilization medicines.
Philadelphia, PennsylvaniaAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,626 recruiting cardiology studies from the U.S. registry right now, out of 14,734 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.