Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,989 recruiting studies in this area right now.
By phase
- Not applicable7,969
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke845
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,986 total
- NCT06009588Recruiting
Comparing Two Heart Valve Types for Aortic Stenosis with Aorta Dilation
This trial tests two types of artificial heart valves—one that expands on its own and one expanded with a balloon—in people with a widened upper aorta. The goal is to see which works better for your condition.
Beijing, Beijing MunicipalityAges 65 years+ - NCT06009718Recruiting
Heart sound and heartbeat analysis study
This study uses artificial intelligence to analyze your heart sounds and heartbeat together to see if this can help understand heart health better. It might lead to easier heart checkups in the future.
ShanghaiAges 18–100 - NCT06010199Recruiting
Biomarker risk study for myocarditis patients
This study looks at certain markers in your blood to better understand the risk level of myocarditis (inflammation of the heart muscle). It may help doctors know how to best monitor and treat your condition.
Xi'an, ShaanxiAges 3–80 - NCT06010641Recruiting
Head-down position for stroke from large artery blockage
This trial tests if lying with the head lower than the body (head-down position) can help people who are having a stroke caused by a blockage in a large artery in the front part of the brain. The goal is to see if this simple position improves blood flow and reduces disability.
ShenyangAges 18 years+ - NCT06010511Recruiting
White matter changes and brain fluid study in older adults
This study uses special MRI scans to look at white matter changes in the brain (often linked to memory problems). It may help doctors understand more about these changes in older adults visiting memory or geriatric clinics.
LeidenAges 65 years+ - NCT06010563Recruiting
Study of a new heart valve for severe pulmonary valve leakage
This study tests a new less-invasive heart valve (VenusP-Valve) for people whose own pulmonary valve is leaking severely. If you qualify, you could get the new valve without open-heart surgery.
Irvine, CaliforniaAges 12 years+ - NCT06010628RecruitingPhase 4
Tenecteplase for stroke 4.5 to 6 hours after onset
This trial tests a medicine called tenecteplase (a clot-buster) for people who have a moderate or severe stroke caused by a clot and can be treated 4.5 to 6 hours after symptoms start. It aims to see if this medicine can help improve recovery.
Shenyang, None SelectedAges 18 years+ - NCT06011018Recruiting
Mirror Therapy with Electrical Stimulation or Sound Beats after Stroke
This study tests if combining mirror therapy with either gentle electrical stimulation or special sound beats can help improve leg movement and brain activity after a stroke. It is designed for people who had their first stroke at least 6 months ago and have some movement in their leg.
Kaohsiung CityAges 20–80 - NCT06013020RecruitingPhase 4
Blood thinner to prevent heart clots after a heart attack
This trial tests a blood thinner, rivaroxaban, to see if it can prevent blood clots from forming in the heart after a specific type of heart attack (STEMI) that affects the front part of the heart.
Zunyi, GuizhouAges 18–75 - NCT06014112Recruiting
Glucose monitor test for heart attack recovery
This study tests a continuous glucose monitor (FSL Pro iQ) in people with heart attack to see if blood sugar patterns can predict recovery. It may help doctors better manage your care after a heart attack.
BéziersAges 18–85 - NCT06014060Recruiting
Shorter vs. longer blood thinner therapy after stenting for high Lp(a)
This trial compares 12 months versus 24 months of dual antiplatelet therapy (two blood thinners) after a stent placement in people with high lipoprotein(a) levels. It aims to see if longer treatment reduces heart risks without increasing bleeding.
Beijing, Beijing MunicipalityAges 18–75 - NCT06014515RecruitingEarly Phase 1
Single injection PET scan to study body metabolism
This study uses a single injection and a special type of PET scan to look at how your body's tissues use fuel (metabolism). It helps researchers learn more about normal and disease-related changes in the heart, liver, and other organs.
Sacramento, CaliforniaAges 18 years+ - NCT06014723Recruiting
Balloon angioplasty for recent minor stroke or TIA
This study tests a balloon procedure to open a narrowed artery in the brain to prevent further strokes. It is for people who recently had a mild stroke or high-risk TIA from a significant blockage.
Changchun, JilinAges 30–80 - NCT06015542RecruitingPhase 2
Giving Elranatamab at Home for Relapsed Multiple Myeloma
This study tests if people with relapsed multiple myeloma can safely give themselves a medicine called elranatamab at home. It aims to make treatment more convenient while still being safe and effective.
OdenseAges 18 years+ - NCT06015620Recruiting
Health changes after mini gastric bypass surgery
This study looks at how mini gastric bypass surgery helps with obesity-related health problems and changes in body composition. It aims to see if patients experience improvements in conditions like diabetes or high blood pressure.
Bhubaneswar, OdishaAges 18–65 - NCT06015776Recruiting
Heart cell signals after menopause
This trial studies how heart cells communicate after menopause. Researchers are looking at a chemical signal called purinergic signaling during heart surgery.
Boston, MassachusettsAges 30–88 - NCT06019845Recruiting
MAGiC heart ablation study with magnetic navigation
This study tests a new magnetic system (MAGiC) to guide heart ablation procedures for people with irregular heartbeats. It aims to see if using magnets to steer catheters is safe and effective.
CopenhagenAges 18 years+ - NCT06021808Recruiting
LAA clip vs. blood thinners to prevent stroke in non-paroxysmal AF
This study compares two ways to prevent stroke in people with persistent or long-standing atrial fibrillation (AF): taking a blood thinner (NOAC) or having a minimally invasive procedure to clip off the left atrial appendage (LAA). The goal is to see which approach works better at preventing stroke without causing major bleeding.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06022328Recruiting
Epigenetic age and prognosis in blood cancers
This study looks at how 'epigenetic age' (a measure of certain changes in your DNA) relates to the way blood cancers called myeloproliferative neoplasms (MPNs) develop and progress. It may help doctors better understand and predict the course of these diseases.
BordeauxAges 18 years+ - NCT06022653Recruiting
Aorta and peripheral artery disease registry
This study collects information from people who have had treatment for aorta or peripheral artery disease at Asan Medical Center since 2011. It helps researchers understand how patients are doing over time.
SeoulAges 19 years+ - NCT06023186Recruiting
Effect of mavacamten on heart blood flow in HCM
This study tests whether the drug mavacamten (Camzyos) improves blood flow in the heart's small vessels for people with obstructive hypertrophic cardiomyopathy. You will take mavacamten as prescribed and have a PET/CT scan to measure your heart's blood flow reserve.
Charlottesville, VirginiaAges 18–85 - NCT06023576RecruitingPhase 2
Blood pressure control during breast cancer chemo
This study tests whether careful blood pressure management can help protect the heart during certain types of chemotherapy (anthracyclines) for breast cancer. Participants will use a smart blood pressure device and may also do an exercise test.
Basking Ridge, New JerseyAges 18 years+ - NCT06023888Recruiting
Heart rhythm analysis for persistent atrial fibrillation
This study tests a new way to analyze heart signals in people with long-standing atrial fibrillation that hasn't gotten better with medication. It may help doctors understand your heart rhythm better and guide future treatments.
TaipeiAges 20–80 - NCT06025123Recruiting
Cooling treatment for cardiac arrest before hospital
This trial tests whether cooling the brain through the nose right after a cardiac arrest improves survival. Paramedics will start a cooling treatment within 20 minutes of arriving, and it may help protect your brain while you are unconscious.
ViennaAges 18–79
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,989 recruiting cardiology studies from the U.S. registry right now, out of 15,300 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
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- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.