Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,989 recruiting studies in this area right now.
By phase
- Not applicable7,969
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke845
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,986 total
- NCT06038838Recruiting
Tioga TMVR system feasibility study for mitral regurgitation
This trial tests a new device called the Tioga TMVR system to treat moderate to severe mitral regurgitation (leaky heart valve). It is for people who cannot have standard surgery or other less invasive treatments.
São PauloAges 18 years+ - NCT06039176Recruiting
Learning from the HeartMate 3 device
This study looks at information from the HeartMate 3 LVAD device to learn more about how it works and what it can tell us about the future. It may help people with advanced heart failure who need this specific device.
San Francisco, CaliforniaAges 18–100 - NCT06039735Recruiting
Heart ultrasound study in multiple myeloma treated with RVd
This study looks at how a new heart ultrasound test can measure heart side effects and overall outcomes in people with multiple myeloma who are treated with the RVd drug combination. It may help doctors better understand heart risks during treatment.
Jinan, ShandongAges 18–70 - NCT06040242Recruiting
Exercise and heart rhythm study for ARVC patients
This study looks at how exercise affects heart rhythm in people with ARVC, a genetic heart condition. Participation involves supervised exercise sessions and heart monitoring to better understand safe activity levels.
Zurich, Canton of ZurichAges 14 years+ - NCT06040528Recruiting
Early discharge after heart attack: a registry study
This study looks at patients who go home early after a heart attack. It collects information to see how safe and effective early discharge is.
LondonAges 16 years+ - NCT06041685Recruiting
Warming for artery catheter in children under 2
This trial tests if warming the skin before placing an artery line helps children having heart surgery. It may make the procedure easier and more comfortable.
Yangsan, Gyeongsangnam-doAges Up to 2 years - NCT06041659Recruiting
Brain network changes during moyamoya bypass surgery
This study uses MRI scans to watch how brain networks work while you are asleep during moyamoya bypass surgery. It may help doctors understand how the brain adjusts after the procedure.
Beijing, Beijing MunicipalityAges 18–65 - NCT06041880Recruiting
Calf Stretching for Better Walking in PAD
This study tests whether a simple daily calf-stretching routine can improve walking ability and blood flow in people with peripheral artery disease. It offers a non-drug, non-surgical approach that you can do at home.
University Park, PennsylvaniaAges 40–85 - NCT06043011Recruiting
Registry for non-Hodgkin lymphoma patients on systemic therapy
This registry tracks people with non-Hodgkin lymphoma who are starting a new line of systemic therapy. It collects information to better understand how treatments work in real life, and optionally asks you to fill out surveys about your symptoms and quality of life.
Freiburg im BreisgauAges 18 years+ - NCT06042439Recruiting
Morning vs evening exercise for blood pressure
This study looks at whether doing your exercise in the morning or the evening is better for lowering blood pressure in women after menopause who have high blood pressure. You will be asked to do a supervised exercise program at either time of day for several weeks.
East Lansing, MichiganAges 55–80 - NCT06044259Recruiting
Comparing two surgeries for acute aortic dissection
This trial compares two surgical methods for repairing the main artery (aorta) after a tear (dissection) that starts in the upper chest. One method replaces part of the aorta, and the other adds a stent. The goal is to find which approach works better for patients.
Hong Kong, Hong KongAges 18–80 - NCT06045091RecruitingEarly Phase 1
BCMA-targeted CAR-NK cells for multiple myeloma or plasma cell leukemia
This trial tests an experimental therapy using immune cells (CAR-NK cells) designed to target and kill cancer cells in people with multiple myeloma or plasma cell leukemia that has returned or stopped responding to treatment. The goal is to see if it is safe and effective.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06044922Recruiting
Using heart rate to predict brain injury after cardiac arrest
This study looks at how your heart rate changes (heart rate variability) to predict brain injury after a cardiac arrest. It may help doctors identify brain damage earlier so they can provide better care.
Brest, Brittany RegionAges 18 years+ - NCT06045156Recruiting
Tirofiban after clot-busting for stroke
This trial tests whether giving tirofiban (a blood thinner) shortly after the standard clot-busting drug tenecteplase can improve recovery from a moderate stroke. It is for people who have had a stroke within the last few hours and do not have certain risk factors like irregular heart rhythm or recent bleeding.
Changchun, JilinAges 18 years+ - NCT06045455Recruiting
CT scan to tell stroke from stroke mimics
This trial is testing whether a special type of CT scan can help doctors tell the difference between a stroke and other conditions that look like a stroke (called stroke mimics). If you have a sudden neurologic symptom within the past 24 hours, this study may help get a clearer diagnosis.
Ostrava, Moravian-Silesian RegionAges 18 years+ - NCT06047028Recruiting
Heart MRI scan to assess tissue health
This study uses a special MRI scan to look at heart muscle metabolism in people with heart failure caused by blocked arteries. It may help doctors better understand which heart tissue is still alive and could recover.
Dallas, TexasAges 20–80 - NCT06047106Recruiting
MRI study for kidney transplant from living donor
This study uses special MRI scans after a living-donor kidney transplant to check how well the kidney is working. It aims to see if MRI can help monitor kidney health without needing a biopsy.
LyonAges 18 years+ - NCT06047561Recruiting
Scottish Aortic Stenosis Imaging Study
This study looks at how aortic stenosis (a narrowing of the heart valve) changes over time using imaging and blood tests. It may help doctors better understand and treat this condition.
EdinburghAges 50 years+ - NCT06047782Recruiting
MRI study of atrial scarring and stroke risk
This study uses a special heart MRI to look for scarring in the upper chambers of the heart (atria) that might cause hidden atrial fibrillation after a stroke with no known cause. It may help explain why the stroke happened and guide future treatment.
DijonAges 18 years+ - NCT06047717Recruiting
Virtual reality navigation study for stroke survivors
This study uses virtual reality to understand how vision loss from a stroke affects navigation. You may help researchers learn more by wearing a VR headset and doing simple tasks.
Rochester, New YorkAges 21–75 - NCT06048159Recruiting
Brain stimulation to improve memory after stroke-related aphasia
This study tests a safe, non-invasive brain stimulation called tACS to see if it can help improve short-term memory for sounds and words in people who have trouble speaking after a stroke. If you have aphasia from a left-brain stroke, this treatment might help your brain relearn how to remember and repeat what you hear.
Milwaukee, WisconsinAges 18 years+ - NCT06048250RecruitingPhase 1
Mezigdomide after Abecma for multiple myeloma
This trial tests a new drug called mezigdomide (CC-92480) for people with multiple myeloma who have already received the CAR T-cell therapy Abecma. The goal is to see if mezigdomide can help keep the cancer under control after Abecma.
Duarte, CaliforniaAges 18 years+ - NCT06049420Recruiting
Lifestyle medicine for rural patients with chronic disease
This trial tests whether exercise therapy can help people with two or more chronic conditions like obesity, diabetes, or heart disease. It's designed for rural patients and requires a referral from your doctor.
Lewisburg, West VirginiaAges 18–64 - NCT06048796Recruiting
Early stopping of sedation after cardiac arrest with normal EEG
This study is testing whether it is safe to stop sedation and temperature management early in cardiac arrest patients who have a normal-looking brain wave test (EEG). If you qualify, you would stop sedation sooner than usual, which may help you wake up faster.
Arnhem, GelderlandAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,989 recruiting cardiology studies from the U.S. registry right now, out of 15,300 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.