Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,626 recruiting studies in this area right now.
By phase
- Not applicable7,647
- Phase 4471
- Phase 2470
- Phase 3439
- Phase 1350
- Phase 1/Phase 2161
- Phase 2/Phase 388
Top conditions
- Stroke798
- Heart Failure538
- Hypertension390
- Cardiovascular Diseases374
- Coronary Artery Disease361
- Multiple Myeloma328
- Atrial Fibrillation258
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke138
- Pulmonary Hypertension105
- Myocardial Infarction96
- Congenital Heart Disease83
- Peripheral Arterial Disease80
- Stroke, Ischemic77
- Aortic Valve Stenosis76
- Acute Coronary Syndrome74
- Obesity74
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital67
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine57
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California449
- Alabama195
- Arizona183
- Massachusetts174
- New York165
- Florida141
- Texas122
- Maryland119
- Minnesota118
- Illinois111
Recruiting studies9,626 total
- NCT07192029Recruiting
Balloon catheter for stroke clot removal in the carotid artery
This trial tests whether using a special balloon-guided catheter during clot removal (mechanical thrombectomy) improves outcomes for people with a severe stroke caused by a blockage in the internal carotid artery. The study aims to see if this tool helps remove the clot more safely and effectively.
Fuzhou, FujianAges 18 years+ - NCT07185100Recruiting
Finding early heart failure in at-risk adults across Germany
This study uses heart MRI scans to find unrecognized heart failure in people who have risk factors like diabetes, kidney disease, high blood pressure, or obesity but haven't been diagnosed with heart failure yet. If you join, you will help researchers learn how common hidden heart failure is and take an important step for your own heart health.
BerlinAges 40–69 - NCT07190690Recruiting
Comparing two drug-coated stents for heart attack patients
This trial compares two types of drug-coated stents (one with sirolimus, one with everolimus) in people who have had a heart attack or unstable angina and need a stent. It aims to see which stent works better for new blockages in the heart arteries.
AlicanteAges 18 years+ - NCT07190079Recruiting
New way to diagnose blood clots in the lungs using saline
This study tests a new method using a saline solution and a special imaging belt to quickly diagnose pulmonary embolism (a blood clot in the lungs) in people with acute breathing problems. If successful, it could provide a faster, safer alternative to standard CT scans.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07184892Recruiting
Swallowing therapy after stroke
This study tests if watching swallowing movements (action observation therapy) helps people recover swallowing function after a first-time stroke. It uses a brain imaging technique called fNIRS to see how the brain responds.
Jinan, ShandongAges 18–80 - NCT07188090RecruitingPhase 2
Mozobil for stem cell transplant study
This study tests if adding Mozobil (a drug that helps release stem cells) before stem cell transplant can improve outcomes for people with multiple myeloma, Hodgkin's lymphoma, or non-Hodgkin lymphoma. If you are eligible, you will receive Mozobil along with standard stem cell mobilization medicines.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07185204Recruiting
Early detection and treatment of postpartum preeclampsia in Nepal
This study tests a new way to find and treat women at high risk for preeclampsia after childbirth. It uses a blood test and a medicine called nifedipine to prevent serious complications.
Milwaukee, WisconsinAges 18 years+ - NCT07190781Enrolling by invitation
Building a stent registry for unruptured brain aneurysms
This trial is collecting information from people who already received a specific type of stent (Lattice Flow-Diverting Dense-Mesh Stent) to treat an unruptured brain aneurysm. The goal is to learn how well the stent works and improve future treatments.
Beijing, Beijing MunicipalityAges 18–80 - NCT07184723Recruiting
How doctors treat abdominal aortic aneurysms in Europe
This trial looks at how doctors manage a specific type of enlarged artery in the belly that hasn't burst but is causing symptoms. The goal is to understand current treatment patterns across Europe.
Vienna, State of ViennaAges 18 years+ - NCT07184476Recruiting
Measuring small blood vessels in kids having heart surgery
This study looks at tiny blood vessels in children with specific heart defects during surgery. It may help doctors better understand circulation and improve care.
Boston, MassachusettsAges 1 day–17 years - NCT07184814Recruiting
Takayasu's arteritis with lung artery involvement study
This study looks at people with Takayasu's arteritis that also affects the lungs' blood vessels. Researchers want to understand the disease's behavior and outcomes over time.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07191730Recruiting
Heart risk prediction for cancer patients on certain chemotherapies
This trial uses a special scoring system (ML Score) to predict if you might develop heart problems while receiving anthracycline chemotherapy or HER2-targeted therapies. It helps doctors decide on the best heart monitoring plan before starting treatment.
CaenAges 18 years+ - NCT07188285Enrolling by invitation
Immune system study for active autoimmune diseases
This study uses a blood test called mass spectrometry to look at the immune system in people with active autoimmune diseases. It aims to find patterns that could help doctors better understand and treat these conditions.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06653348RecruitingPhase 2/Phase 3
Ticagrelor-based therapy for recent mild stroke or high-risk TIA
This trial tests whether switching to a simpler antiplatelet medication (ticagrelor) after a mild stroke or high-risk TIA can prevent another stroke while reducing the risk of bleeding. It is for people who have not received clot-busting treatment or had a large stroke.
Sari, MazandaranAges 40 years+ - NCT06734065Recruiting
Heart failure monitoring with a non-invasive lung fluid sensor
This trial tests a new device that measures fluid in your lungs without needles or surgery. It may help your doctor manage heart failure better, especially if you've been in the hospital recently or have symptoms like shortness of breath.
FlenAges 18 years+ - NCT06831825RecruitingPhase 1
Gene therapy for heart failure recovery trial
This trial tests a gene therapy injected into the heart to help it recover after a previous heart attack. It may be an option for people with stable heart failure who are not eligible for standard procedures like stents or bypass surgery.
Houston, TexasAges 18–79 - NCT06946381Recruiting
Study of a stent-graft for aortic and iliac aneurysms
This trial is testing a specific stent-graft system, called E-liac, to treat aneurysms in the aorta or iliac arteries. It may be used alone or with other devices. The study will track how well it works.
Bari, BAAges Any age - NCT06946082Recruiting
Stroke study: arm and language skills in Turkish speakers
This study looks at how arm movement, body control, and mental imagery (imagining movement without actually doing it) relate to Turkish language abilities after a stroke. It aims to understand how these functions work together to help recovery.
IzmirAges 18 years+ - NCT06947707Recruiting
Blood thinners for brain blood clot in Chinese patients
This trial tests two blood thinner medicines, edoxaban and rivaroxaban, in Chinese patients with a blood clot in a brain vein (cerebral venous thrombosis). It aims to see if these medicines are safe and work well.
Beijing, Beijing MunicipalityAges 18–80 - NCT06947174Recruiting
Using CT scans to choose the right balloon pump size
This study looks at whether measurements from a CT scan can help doctors choose the right size of a balloon pump placed in the aorta to support the heart. If you're having an angiography and have had a recent CT scan, you might be able to join.
Bangkok Noi, BangkokAges 18 years+ - NCT06947343Recruiting
Action observation vs motor relearning for stroke balance
This study compares two types of therapy—watching actions and a standard motor relearning program—to see which helps stroke survivors improve their balance and walking. If you are able to stand briefly, you may benefit from this extra rehab.
IslamabadAges 45 years+ - NCT06946732Recruiting
Acostream for high-risk and intermediate-risk pulmonary embolism
This trial is testing a device (called the Acostream) to break up blood clots in the lungs for people with serious pulmonary embolism who cannot receive standard clot-busting drugs or surgery. It may be an option if you have high-risk or intermediate-risk PE and are between 18 and 85.
Shanghai, Shanghai MunicipalityAges 18–85 - NCT06494501RecruitingPhase 3
Preventing heart attacks in middle-aged adults with early plaque
This study tests whether starting cholesterol-lowering treatment early can prevent heart attacks in people aged 30-50 who already have early signs of artery plaque but no history of heart disease.
New York, New YorkAges 30–50 - NCT05300971Recruiting
Heat therapy to lower blood pressure in midlife and older adults
This study tests whether regularly using passive heat can lower your systolic blood pressure (the top number) and improve how your blood vessels work. If you’re eligible, you may be randomly assigned to try the heat therapy as a 6-month program.
Boulder, ColoradoAges 40 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,626 recruiting cardiology studies from the U.S. registry right now, out of 14,734 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.