Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,989 recruiting studies in this area right now.
By phase
- Not applicable7,969
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke845
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,986 total
- NCT06049654Recruiting
Comparing Allegra and Sapien valves for valve-in-valve procedure
This trial tests two different replacement heart valves (Allegra and Sapien) to see which works better for people who need a new valve placed inside a previously implanted surgical valve. It aims to help patients with a failing biological aortic valve who are already scheduled for this procedure.
AlessandriaAges 18 years+ - NCT06051032Recruiting
Comparing balloon vs. suction for clotted dialysis fistulas
This study compares two ways to clear a sudden clot in a dialysis fistula (AVF). It uses either a balloon (to push the clot out) or a suction device (to pull the clot out) to restore blood flow.
Valencia, ValenciaAges 18 years+ - NCT06052826RecruitingPhase 2
Geriatric support to speed recovery after CAR-T for older adults
This study tests whether extra geriatric support before and after CAR-T cell therapy helps people 60 and older recover faster. It is for patients with B-cell non-Hodgkin lymphoma or multiple myeloma who are scheduled for an FDA-approved CAR-T treatment.
Duarte, CaliforniaAges 60 years+ - NCT06052475Recruiting
Pacemaker upgrade study for heart failure
This trial is for people with a standard pacemaker that stimulates the right ventricle most of the time. It tests whether a newer type of pacemaker (CRT) can improve heart function and symptoms. If you have a weakened heart (LVEF between 35-50%) and your heart failure has gotten worse, this study may be a good fit.
CambridgeAges 18 years+ - NCT06052969Recruiting
Pulse NanoMED MicroBeads after clot removal for stroke
This trial tests a new treatment called Pulse NanoMED MicroBeads for people who still have a blocked brain artery after a standard clot removal procedure (mechanical thrombectomy). The goal is to see if these tiny beads can clear the remaining blockage and improve blood flow to the brain.
Columbia, South CarolinaAges 18–85 - NCT06053320Recruiting
Stroke rehab study using brain stimulation and movement training
This study tests whether a type of brain stimulation combined with movement training can help people who have had a right-side stroke improve their arm and hand function. It also includes healthy adults to compare results.
Atlanta, GeorgiaAges 18–90 - NCT06053580RecruitingPhase 2
Valsartan for pulmonary hypertension: protection study
This trial tests whether a blood pressure medicine called valsartan can help protect the lungs and heart in people with a specific type of pulmonary hypertension (Group 1 PAH). If you have PAH and are stable enough to walk 50 meters, you may be able to join.
Seattle, WashingtonAges 18–80 - NCT06053619Recruiting
Virtual reality walking rehab for stroke patients who cannot walk
This trial tests whether adding virtual reality to robot-assisted walking therapy helps people who have had a stroke and cannot walk. It is for patients who had a first stroke in the past 15 days to 6 months.
LimogesAges 35–75 - NCT06053645Recruiting
Weight and heart disease study
This study looks at how being overweight affects heart health. It tests a program that includes monthly check-ins and surveys, and is for people with a BMI of 30 or higher who also have a heart condition. The goal is to learn more about how to help people with both weight and heart concerns.
Rochester, MinnesotaAges 18 years+ - NCT06054516Recruiting
Study of heart metabolism in ischemic heart disease using advanced imaging
This trial uses a special imaging technique (hyperpolarized MRSI) to study metabolism in the heart muscle of people with chronic heart failure caused by ischemic heart disease. It aims to help doctors better understand how the heart uses energy.
Aarhus, Central JutlandAges 18–90 - NCT06055894Recruiting
Plant-based diet and supplements for smoldering myeloma or MGUS
This study tests whether a plant-based diet and certain supplements can help people with smoldering multiple myeloma (SMM) or monoclonal gammopathy of undetermined significance (MGUS). Participants will learn to cook plant-based recipes and track their meals using a phone app.
Basking Ridge, New JerseyAges 18 years+ - NCT06055036Recruiting
Stress reduction for heart health in Black men
This study looks at how reducing stress can improve cardiovascular health in Black men. It involves lifestyle changes and support to help lower your risk of heart disease.
Columbus, OhioAges 18 years+ - NCT06055452RecruitingPhase 4
SGLT2 Inhibitors for Pre-Heart Failure with Hypertension
This trial tests if a medicine (SGLT2 inhibitor) given to people with high blood pressure and early signs of heart stress can help prevent heart failure. You may join if your blood pressure is controlled but tests show your heart is beginning to struggle.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06055569Recruiting
Rehabilitation for arm recovery after stroke using observation and muscle stimulation
This trial tests if observing arm movements paired with muscle stimulation helps stroke survivors regain arm function. It may be an option if your stroke affected one arm and you are between two weeks and six months post-stroke.
Milan, ItaliaAges 18 years+ - NCT06055751Recruiting
Heart rhythm monitoring after aortic valve replacement
This trial studies people who had a heart valve procedure called TAVI and later had a heart rhythm problem. You will get a tiny heart monitor placed under your skin to track your heart rhythm over time and help doctors understand how common these problems are.
Kansas City, MissouriAges 18 years+ - NCT06056271Recruiting
Tracking AI use during AF ablation in real-world care
This trial is for people with atrial fibrillation (AF) who are having or recently had a catheter ablation procedure. It looks at how using a special artificial intelligence tool, called VX1, during the procedure affects patient outcomes.
Evanston, IllinoisAges 21 years+ - NCT06056297RecruitingPhase 3
Study of Mavorixafor for chronic neutropenia with infections
This trial tests if mavorixafor can help people with certain types of long-term low neutrophil counts (chronic neutropenia) who still get frequent or serious infections. It aims to reduce infection risk by boosting your body's infection-fighting cells.
Phoenix, ArizonaAges 12 years+ - NCT06056921RecruitingPhase 1
CAR T-cell therapy for hard-to-treat autoimmune diseases
This trial tests a new treatment using your own immune cells (CAR T-cells) targeting a protein called CD19 to control severe autoimmune diseases like lupus, Sjogren's, scleroderma, dermatomyositis, or vasculitis. The goal is to see if it's safe and can improve symptoms when other treatments haven't worked.
Taiyuan, ShanxiAges 18 years+ - NCT06057844Recruiting
PET scan to detect active blood clots
This study uses a special PET scan to see if it can detect active blood clots. It is looking for healthy volunteers to help test the imaging method, not people who already have a clot.
BrestAges 18 years+ - NCT06057129Recruiting
Hand therapy at home after stroke using the ReHandyBot
This trial tests a home-use hand device (ReHandyBot) to help you practice hand movements after a recent stroke. It is designed for people who can still move their arm a little but need more therapy, and who can set up the device in their own home.
Brissago, Canton TicinoAges 18–90 - NCT06057584Recruiting
Sensory and motor training for arm recovery after stroke
This study tests a special training program that combines touch and movement exercises to help people who have had a stroke improve the use of their affected arm and hand. It is designed for those who still have some movement but also have trouble with sensation.
Taipei, TaiwanAges 20 years+ - NCT06057402RecruitingPhase 4
Continued access to elranatamab for multiple myeloma
This trial offers continued access to elranatamab for people with multiple myeloma who were already benefiting from it in a previous study and whose earlier study ended.
Irvine, CaliforniaAges 18 years+ - NCT06058182Recruiting
Rna biomarkers for heart attack patients
This study looks at RNA markers in the blood of people having their first heart attack to see if they can predict recovery. If you are scheduled for a procedure to open blocked arteries, you may be able to join.
Milan, MilanAges 18 years+ - NCT06059053Recruiting
Study of the Semibranch device for aortic problems
This study is testing a new stent-graft device (Semibranch) to treat aneurysms or other problems in the main artery near the kidneys or in the chest and belly. It follows patients who get this treatment to see how well it works.
MünsterAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,989 recruiting cardiology studies from the U.S. registry right now, out of 15,300 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.