Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,626 recruiting studies in this area right now.
By phase
- Not applicable7,647
- Phase 4471
- Phase 2470
- Phase 3439
- Phase 1350
- Phase 1/Phase 2161
- Phase 2/Phase 388
Top conditions
- Stroke798
- Heart Failure538
- Hypertension390
- Cardiovascular Diseases374
- Coronary Artery Disease361
- Multiple Myeloma328
- Atrial Fibrillation258
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke138
- Pulmonary Hypertension105
- Myocardial Infarction96
- Congenital Heart Disease83
- Peripheral Arterial Disease80
- Stroke, Ischemic77
- Aortic Valve Stenosis76
- Acute Coronary Syndrome74
- Obesity74
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital67
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine57
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California449
- Alabama195
- Arizona183
- Massachusetts174
- New York165
- Florida141
- Texas122
- Maryland119
- Minnesota118
- Illinois111
Recruiting studies9,626 total
- NCT05257629RecruitingPhase 3
Aggressive smoking quit program after heart problems
This trial tests whether a strong quit plan using varenicline (a quit pill) plus nicotine e-cigarettes, along with counseling, helps people stop smoking after a recent heart-related event. It’s aimed at people who want to quit and can safely stay involved for about a year.
New Westminster, British ColumbiaAges 18 years+ - NCT07181512Recruiting
AI screening for coronary artery disease on chest CT
This trial uses artificial intelligence (AI) to look at chest CT scans for signs of coronary artery disease. It may help find blockages without needing a separate heart-specific CT scan.
Hangzhou, ZhejiangAges 18 years+ - NCT07181213Enrolling by invitation
Genetic links to high blood pressure
This trial is for people who took part in a large study (SCAPIS) and have both a certain genetic trait and high blood pressure. The goal is to understand how your genes may affect blood pressure.
Linköping, Östergötland CountyAges 50 years+ - NCT06322017Recruiting
Early vein isolation for atrial fibrillation in older adults
This study compares doing vein isolation soon after diagnosis versus usual care in people 75+ with new or early atrial fibrillation. The goal is to see if early treatment prevents the condition from getting worse and improves quality of life.
Nantes, Loire AtlantiqueAges 75 years+ - NCT07178509Recruiting
Heart artery study using stress ultrasound
This study uses a stress echocardiogram (ultrasound of the heart during exercise or medicine) to look at blood flow in people who have had a spontaneous tear in a heart artery (SCAD) and in healthy volunteers. It aims to learn more about how SCAD affects the heart.
Rochester, MinnesotaAges 18 years+ - NCT07181434Recruiting
Virtual reality for pain relief during leg artery repair
This trial tests whether using a virtual reality headset during a leg artery repair procedure can reduce pain. If you have peripheral artery disease and are having a minimally invasive leg artery surgery under local anesthesia with sedation, you may be able to participate.
PoitiersAges 18 years+ - NCT07176260Recruiting
Blood cell function and stress in pulmonary hypertension
This study looks at how blood cells work and handle stress in people with certain types of pulmonary hypertension. By understanding these processes, doctors hope to improve diagnosis and treatment.
Strasbourg, Bas-RhinAges 18 years+ - NCT07181317Recruiting
Long-term study of young women after heart attack
This study continues to follow young women who had a heart attack to learn more about their long-term health. You can join if you already took part in the earlier WAMIF study.
ParisAges 18–60 - NCT07179705Recruiting
Predicting low blood pressure during dialysis in the ICU
This trial tests if a special tool can predict and prevent dangerous drops in blood pressure during dialysis in ICU patients with kidney problems. It might help make dialysis safer and more comfortable.
BangkokAges 18 years+ - NCT07179887Recruiting
Arm cuff treatment for better brain blood flow in older adults
This trial tests if a simple, at-home arm cuff treatment (Remote Ischaemic Conditioning) can improve blood flow regulation in the brain of older adults. It may help understand how to protect brain health as we age.
Derby, DerbyshireAges 65–85 - NCT07175532Recruiting
Registry for mitral stenosis balloon treatment
This study tracks patients with a heart valve condition called mitral stenosis who are getting a procedure called percutaneous mitral balloon commissurotomy, or PMBC. It aims to see how well the procedure helps improve their symptoms and health over time.
SeoulAges 18–89 - NCT07177612Enrolling by invitation
Testing the LILAC method for lipoprotein(a) education
This trial tests a new method called LILAC to help people learn about and manage high levels of lipoprotein(a), a type of fat in the blood. It is for anyone 16 or older who attends educational events or is part of a health group.
PerthAges 16 years+ - NCT07183605Recruiting
How different ways of drawing blood from a central line compare for heparin activity
This trial checks whether blood samples taken from a central line using either a syringe flush or a vacuum tube give the same heparin activity results as blood from a vein in the arm. It is designed for patients in the ICU who are on a steady heparin drip.
OrléansAges 18 years+ - NCT07179536Recruiting
Early Walking After Artery Closure Device
This trial tests if patients can safely walk sooner after a leg artery procedure when a special closure device (ProGlide) is used. It aims to find the best time to get up and move, which could mean faster recovery.
Beijing, Beijing MunicipalityAges 18–75 - NCT07181941RecruitingPhase 1/Phase 2
Testing lower doses of linvoseltamab for multiple myeloma
This trial tests if a lower dose of linvoseltamab can still work well for people with multiple myeloma that has come back or not responded to treatment. It aims to reduce side effects while keeping the cancer under control.
Seattle, WashingtonAges 18 years+ - NCT07180992Recruiting
Monocytes and CART cell response in multiple myeloma
This trial looks at how certain immune cells (monocytes) affect the success of CART cell therapy for multiple myeloma. It may help doctors improve treatment for future patients.
AmiensAges 18 years+ - NCT07179991Recruiting
DDAVP (desmopressin) for bleeding during heart surgery
This study tests whether a medicine called desmopressin (DDAVP) can reduce bleeding during heart surgery. It uses a special blood test (TEG6) to decide who gets the medicine.
London, OntarioAges 18 years+ - NCT07178145RecruitingPhase 4
Heart fat and heart failure with preserved pumping ability study
This study looks at fat around the heart in people with heart failure where the heart still pumps normally. It uses MRI scans to understand this fat better, and may help find new treatments.
Charlottesville, VirginiaAges 18–90 - NCT07176546RecruitingPhase 2/Phase 3
Testing TAVNEOS for ear, nose, and throat symptoms in GPA
This trial tests a new drug called TAVNEOS (avacopan) for people with Granulomatosis with Polyangiitis (GPA) whose symptoms affect the ears, nose, or throat. The goal is to see if this drug can reduce inflammation and improve these symptoms better than current treatments.
Edison, New JerseyAges 18 years+ - NCT07176507Recruiting
Study of multiple and mixed heart valve disease
This study looks at people who have two or more heart valve problems that are moderate to severe. It aims to learn more about this condition and how to best manage it.
LilleAges 18 years+ - NCT07174986RecruitingPhase 2/Phase 3
Double defibrillation for out-of-hospital cardiac arrest
This trial tests whether giving two shocks in a row (instead of one) helps restart the heart in people who have a cardiac arrest outside the hospital and need a defibrillator.
AmsterdamAges 18 years+ - NCT07177989Recruiting
Breathing and exercise for better blood pressure
This study tests whether combining a special breathing technique with aerobic interval training (short bursts of exercise) can help lower blood pressure and heart strain in people with hypertension. It may offer a safe, drug-free way to manage your condition.
RawalpindiAges 25–50 - NCT07179029Recruiting
Can anesthesia affect the heart during non-cardiac surgery?
This study looks at whether anesthesia can cause heart damage during non-cardiac surgeries. If you have certain health risks, participating may help doctors learn how to better protect your heart.
TübingenAges 40–80 - NCT07178600Recruiting
Eye drops for surgery: side effects study
This study looks at how patients react to a common eye drop used before surgery. It helps understand side effects and who might be affected.
Mexico City, Mexico CiyAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,626 recruiting cardiology studies from the U.S. registry right now, out of 14,734 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.