Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,609 recruiting studies in this area right now.
By phase
- Not applicable7,632
- Phase 4472
- Phase 2469
- Phase 3439
- Phase 1350
- Phase 1/Phase 2160
- Phase 2/Phase 387
Top conditions
- Stroke797
- Heart Failure534
- Hypertension388
- Cardiovascular Diseases373
- Coronary Artery Disease363
- Multiple Myeloma327
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction97
- Congenital Heart Disease84
- Peripheral Arterial Disease79
- Stroke, Ischemic78
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital68
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California453
- Alabama196
- Arizona181
- Massachusetts173
- New York168
- Florida140
- Texas122
- Maryland118
- Minnesota117
- Illinois112
Recruiting studies9,609 total
- NCT04674969Recruiting
Register patients receiving a drug-eluting device for leg arteries
This study is a real-world registry that follows adults who receive a drug-eluting device for narrowed or blocked blood vessels in the legs (peripheral vasculature). It helps researchers understand how these devices perform in everyday care.
Jonesboro, ArkansasAges 18 years+ - NCT06948084RecruitingPhase 2
New drug combo vs usual care for high-risk multiple myeloma
This trial tests whether a new combination of drugs (daratumumab and teclistamab) works better than the usual treatments for multiple myeloma that has come back or stopped responding, especially in people with a high-risk form of the disease. Participants will be randomly assigned to get either the new combo or one of the standard combos.
Coeur d'Alene, IdahoAges 18 years+ - NCT03409159Recruiting
Left atrial appendage closure registry in Austria
This study keeps records of people who already had a procedure to close a part of the heart called the left atrial appendage in Austria. It helps doctors understand outcomes and safety for patients after the procedure.
GrazAges 18 years+ - NCT06471036Recruiting
Improving cholesterol testing and treatment after a heart attack
This study tests whether giving extra education to doctors and patients can help improve cholesterol management after a heart-related hospitalization. It aims to see if a simple program can make sure patients get the right testing and treatment for high cholesterol.
Minneapolis, MinnesotaAges 18 years+ - NCT07574593Recruiting
Heart Failure Sensor Implant Study
This study tests a small sensor placed in a vein to help monitor and manage heart failure. The sensor tracks fluid buildup in your heart and may help doctors adjust your treatment to keep you feeling better and out of the hospital.
Chula Vista, CaliforniaAges 18 years+ - NCT07727304Enrolling by invitation
Acute heart failure checklist in the emergency department
This study tests a checklist to help doctors better manage patients who come to the emergency department with sudden or worsening shortness of breath caused by acute heart failure. The goal is to improve care and outcomes for these patients.
Ottawa, OntarioAges 18 years+ - NCT07862933Recruiting
AI chat support for older adults with heart failure
This study tests an AI-powered chat system that offers social support to older adults with chronic heart failure. It may help you feel more supported and manage your condition better.
New Taipei City, New Taipei CityAges 60 years+ - NCT06917378Recruiting
Study on blocked heart arteries over 3 months
This trial tests a procedure for people with a completely blocked heart artery that has been present for at least 3 months. It aims to see if opening the blockage can improve blood flow and heart function.
New Taipei CityAges 20–120 - NCT05376267Recruiting
Testing how long cooling lasts after pediatric cardiac arrest
This study tests whether using body cooling for different lengths of time helps children recover better after an out-of-hospital cardiac arrest. It focuses on children who remain very unresponsive after resuscitation and need a breathing tube and steady temperature control.
Birmingham, AlabamaAges 2 days–17 years - NCT07249853RecruitingPhase 3
Cilostazol to prevent brain damage after aneurysm surgery
This trial tests if a medicine called cilostazol can reduce the risk of a delayed shortage of blood in the brain after having a bleeding aneurysm treated. It aims to improve recovery by preventing a common complication called delayed cerebral ischemia.
Beijing, Beijing MunicipalityAges 18–80 - NCT06154395Recruiting
Improving heart blood flow after a first heart attack
This study tests a way to improve blood flow in the small vessels of the heart after a first heart attack. It is for people who have a specific type of heart attack in the front part of the heart and are treated quickly with a catheter procedure.
Harbin, HeilongjiangAges 18 years+ - NCT03197363Enrolling by invitation
Long-term study of adults living in Białystok
This study follows adults living in Białystok over time to learn about health and life patterns. If you’re invited to take part and agree, it may help researchers better understand community health.
BialystokAges 20–80 - NCT07830758RecruitingPhase 1
Resmetirom for fatty liver disease with heart failure
This trial tests a drug called resmetirom for people who have both a type of fatty liver disease (MASH) and a type of heart failure (HFpEF). It aims to see if the drug can help both conditions. You may be able to join if you have both conditions and meet certain health criteria.
Peoria, ArizonaAges 18 years+ - NCT06904066RecruitingPhase 1
Personalized T cell therapy for blood cancers
This trial tests a treatment that takes your own immune cells, modifies them to attack cancer cells, and gives them back to you. It is for people with certain blood cancers who have specific gene changes.
Bethesda, MarylandAges 18–120 - NCT07462741Recruiting
Education program for diabetic hemodialysis patients
This study tests if a special education program helps people with diabetes who are on hemodialysis (a type of kidney treatment). The goal is to see if learning more about managing their health can improve their overall well-being.
Elâzığ, MerkezAges 18 years+ - NCT06307262Recruiting
European registry for tricuspid valve repair
This trial is a registry that collects information on patients who have had a minimally invasive procedure to fix a leaky tricuspid valve. By joining, you help doctors learn more about how well these devices work over time.
Munich, BavariaAges 18 years+ - NCT07192952RecruitingPhase 3
Long-term safety of finerenone for children with heart failure
This trial tests a medicine called finerenone to see if it is safe for children and young adults with heart failure when taken for a long time. It may help improve heart function and manage symptoms.
Aurora, ColoradoAges Up to 18 years - NCT06321302RecruitingPhase 2
Study of BI 764524 for diabetic retinopathy
This study tests an investigational drug called BI 764524 for people with moderate to severe diabetic retinopathy, a complication of diabetes that can damage the retina. The goal is to see if the treatment can help prevent vision loss.
Phoenix, ArizonaAges 18 years+ - NCT07200102RecruitingPhase 1
Selinexor after CAR-T for high-risk multiple myeloma
This study tests whether taking selinexor after CAR-T cell therapy can help keep multiple myeloma from coming back. It is for people whose myeloma is high-risk or still has signs of disease after CAR-T.
St Louis, MissouriAges 18 years+ - NCT07141251Recruiting
Custom stent-graft procedure for complex aortic aneurysm repair
This study tests a new way to repair a complex aortic aneurysm (a bulge in the main artery) using a special procedure that helps keep blood flowing to your vital organs. It may help people who are not candidates for standard surgery. The goal is to see if this approach is safe and works well.
Beijing, Beijing MunicipalityAges 18–80 - NCT07188805RecruitingPhase 3
Finerenone for children with heart failure
This study tests a medicine called finerenone in children with heart failure. It looks at whether finerenone helps the heart work better and is safe compared to a placebo (a dummy pill), when taken with the usual heart-failure medicines.
Aurora, ColoradoAges 6 months–17 years - NCT05735704Recruiting
Blood cancer early detection study
This study looks for early signs of blood cancers in people who have them or are at higher risk, like family members or older adults. It aims to find cancer sooner, which may lead to better outcomes.
OlomoucAges 18 years+ - NCT07874594Recruiting
Brain training to improve sleep after a first stroke
This study tests a treatment that may help reduce brain inflammation and improve sleep in people who have had a first stroke and now have trouble sleeping. It uses a non-invasive technique called remote ischemic conditioning, which involves brief, repeated cycles of a blood pressure cuff on the arm.
Chengdu, SichuanAges 18–80 - NCT07562932Recruiting
Norepinephrine vs dopamine for cardiogenic shock
This study compares two blood pressure support medicines (norepinephrine and dopamine) in adults with cardiogenic shock, a condition where the heart cannot pump enough blood. It aims to find which medicine works better for patients with this severe heart condition.
Gwangju, Jeollanam-doAges 19 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,609 recruiting cardiology studies from the U.S. registry right now, out of 14,617 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.